Spots Global Cancer Trial Database for pleomorphic xanthoastrocytoma

Every month we try and update this database with for pleomorphic xanthoastrocytoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy	NCT05180825	Grade 1 Glioma Mixed Glio-neur... Pleomorphic Xan...	Trametinib Vinblastine	1 Month - 25 Years	University Hospital, Strasbourg, France
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors	NCT02684058	Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Ipon...	Dabrafenib trametinib Carboplatin Vincristine	12 Months - 17 Years	Novartis
Pediatric Long-Term Follow-up and Rollover Study	NCT03975829	Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Lipo... Neurofibromatos...	dabrafenib trametinib	1 Year -	Novartis
Pediatric Long-Term Follow-up and Rollover Study	NCT03975829	Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Lipo... Neurofibromatos...	dabrafenib trametinib	1 Year -	Novartis
A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas	NCT01837862	Pilomyxoid Astr... Pilocytic Astro... Glioma, Astrocy... Optic Nerve Gli... Pleomorphic Xan... Glioblastoma Mu... Anaplastic Astr... Gliosarcoma Diffuse Intrins... DIPG Low-grade Gliom... Brainstem Gliom...	Mebendazole Vincristine Carboplatin Temozolomide Bevacizumab Irinotecan	1 Year - 21 Years	Northwell Health
Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy	NCT05180825	Grade 1 Glioma Mixed Glio-neur... Pleomorphic Xan...	Trametinib Vinblastine	1 Month - 25 Years	University Hospital, Strasbourg, France
Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Pediatric Patients With BRAF V600 Mutation Positive LGG or Relapsed or Refractory HGG Tumors	NCT02684058	Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Ipon...	Dabrafenib trametinib Carboplatin Vincristine	12 Months - 17 Years	Novartis
Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms	NCT04541082	Central Nervous... Glioblastoma Gliosarcoma, Ad... Anaplastic Olig... Anaplastic Astr... Pilocytic Astro... Oligodendroglio... Gliomatosis Cer... Pleomorphic Xan... Anaplastic Pleo... Diffuse Midline... Ependymoma Ependymoma, Ana... Medulloblastoma Teratoid Rhabdo... Neuroectodermal... Neuroectodermal... Anaplastic Meni... Atypical Mening... Choroid Plexus ... Pineal Tumor Diffuse Astrocy... Glial Tumor	ONC206	18 Years -	Chimerix
Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy	NCT05180825	Grade 1 Glioma Mixed Glio-neur... Pleomorphic Xan...	Trametinib Vinblastine	1 Month - 25 Years	University Hospital, Strasbourg, France
Pediatric Long-Term Follow-up and Rollover Study	NCT03975829	Diffuse Astrocy... Anaplastic Astr... Astrocytoma Oligodendroglio... Anaplastic Olig... Glioblastoma Pilocytic Astro... Giant Cell Astr... Pleomorphic Xan... Anaplastic Pleo... Angiocentric Gl... Chordoid Glioma... Gangliocytoma Ganglioglioma Anaplastic Gang... Dysplastic Gang... Desmoplastic In... Papillary Glion... Rosette-forming... Central Neurocy... Extraventricula... Cerebellar Lipo... Neurofibromatos...	dabrafenib trametinib	1 Year -	Novartis
Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma	NCT04065776	Glioma Pilocytic Astro... Pilomyxoid Astr... Pleomorphic Xan... Ganglioglioma Optic Pathway G... Diffuse Astrocy...	Hippocampal-avo...	6 Years - 21 Years	St. Jude Children's Research Hospital
Social Determinants of Health in Glioblastoma Population	NCT03900689	Glioma Astrocytoma Oligodendroglio... Ependymoma Ganglioglioma Pleomorphic Xan...	Part 1 Survey G... Part 2 Focus Gr...	18 Years -	Wake Forest University Health Sciences
Social Determinants of Health in Glioblastoma Population	NCT03900689	Glioma Astrocytoma Oligodendroglio... Ependymoma Ganglioglioma Pleomorphic Xan...	Part 1 Survey G... Part 2 Focus Gr...	18 Years -	Wake Forest University Health Sciences

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