Spots Global Cancer Trial Database for precision oncology

Every month we try and update this database with for precision oncology cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry	NCT03452774	Cancer, Metasta... Cancer Cancer of Pancr... Cancer of Liver Cancer of Stoma... Cancer Liver Cancer of Rectu... Cancer of Kidne... Cancer of Esoph... Cancer of Cervi... Cancer of Colon Cancer of Laryn... Cancer, Lung Cancer, Breast Cancer, Advance... Cancer Prostate Cancer of Neck Cancer of Skin Neuroendocrine ... Carcinoma Mismatch Repair... BRCA Gene Rearr... Non Hodgkin Lym... Leukemia Non Small Cell ... Cholangiocarcin... Glioblastoma Central Nervous... Melanoma Urothelial Carc... Bladder Cancer Ovarian Cancer Endometrial Can... Testicular Canc... Breast Cancer COVID Myelofibrosis Myeloproliferat... Myeloproliferat... Follicular Lymp... Mantle Cell Lym... Marginal Zone L... Myelodysplastic...	Clinical Trial ...	-	Massive Bio, Inc.
Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies	NCT04541108	Solid Tumor	Rilvegostomig Volrustomig Sabestomig Pembrolizumab	18 Years -	Presage Biosciences
Phase 1/2a Study of SQ3370 in Patients With Advanced Solid Tumors	NCT04106492	Cancer	SQ3370	18 Years -	Shasqi, Inc.
PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, and Sabestomig in HNSCC	NCT06366451	Head and Neck S...	Rilvegostomig Volrustomig Sabestomig Pembrolizumab	18 Years -	Presage Biosciences
A Phase II Randomized Therapeutic Optimization Trial for Subjects With Refractory Metastatic Colorectal Cancer Using ctDNA: Rapid 1 Trial	NCT04786600	Metastatic Colo...	Signatera ctDNA... pre-specified s...	18 Years - 99 Years	University of Florida
Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors	NCT04683939	Solid Tumor Gastric Cancer Gastroesophagea... Esophageal Aden... Pancreatic Canc... Biliary Tract C... Cholangiocarcin... Metastatic Canc...	BNT141 Nab-paclitaxel Gemcitabine	18 Years -	BioNTech SE
Intratumoral Microdosing of TAK-981 in Head and Neck Cancer	NCT04065555	Head and Neck C...	TAK-981 Cetuximab Avelumab TAK-981 + Cetux... TAK-981 + Avelu...	18 Years -	Presage Biosciences
Phase II Study Using Genomic & Proteomic Profiling to Influence Treatments for Patients With Metastatic Breast Cancer	NCT02008994	Metastatic Brea...	Genomic and Pro...	18 Years -	Sanford Health
Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies	NCT04541108	Solid Tumor	Rilvegostomig Volrustomig Sabestomig Pembrolizumab	18 Years -	Presage Biosciences
Phase 1/2a Study of SQ3370 in Patients With Advanced Solid Tumors	NCT04106492	Cancer	SQ3370	18 Years -	Shasqi, Inc.
Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies	NCT04541108	Solid Tumor	Rilvegostomig Volrustomig Sabestomig Pembrolizumab	18 Years -	Presage Biosciences
A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations	NCT05199584	Solid Tumors Wi...	ENV-101 (talade...	18 Years -	Endeavor Biomedicines, Inc.
CIVO Intratumoural Microdosing of Anti-Cancer Therapies in Australia	NCT04891718	Solid Tumour	MVC-101 Nivolumab MVC-101 + Nivol...	18 Years -	Presage Biosciences
PBI-MST-01(NCT04541108) Substudy TAK-02: Intratumoral Microdosing of TAK-676 in HNSCC	NCT06062602	Head and Neck S...	TAK-676 Carboplatin 5-FU Paclitaxel TAK-676 + Carbo... Carboplatin + P... Carboplatin + 5... TAK-676 + Carbo... TAK-676 + Carbo...	18 Years -	Presage Biosciences
Precise Local Injection of Anti-cancer Drugs Using Presage's CIVO Device in Soft Tissue Sarcoma	NCT03056599	Soft Tissue Sar...	Multiple drug m... CIVO device	18 Years -	Presage Biosciences
Intratumoral Microdosing of TAK-981 in Head and Neck Cancer	NCT04065555	Head and Neck C...	TAK-981 Cetuximab Avelumab TAK-981 + Cetux... TAK-981 + Avelu...	18 Years -	Presage Biosciences

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