Spots Global Cancer Trial Database for central nervous system tumor
Every month we try and update this database with for central nervous system tumor cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Longitudinal Study of Biomarkers | NCT01595126 | Central Nervous... | 1 Day - 21 Years | Ann & Robert H Lurie Children's Hospital of Chicago | ||
| Tissue Collection for Drug Screening and Bioanalysis | NCT04852354 | Pediatric Centr... Central Nervous... | - | Weill Medical College of Cornell University | ||
| Somatic Mosaicism in Twins Discordant for Childhood Cancer | NCT06054295 | Pediatric Centr... Central Nervous... Discordant Twin Somatic Mutatio... | Biospecimen col... Questionnaire A... | - 18 Years | Children's Oncology Group | |
| SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry | NCT03452774 | Cancer, Metasta... Cancer Cancer of Pancr... Cancer of Liver Cancer of Stoma... Cancer Liver Cancer of Rectu... Cancer of Kidne... Cancer of Esoph... Cancer of Cervi... Cancer of Colon Cancer of Laryn... Cancer, Lung Cancer, Breast Cancer, Advance... Cancer Prostate Cancer of Neck Cancer of Skin Neuroendocrine ... Carcinoma Mismatch Repair... BRCA Gene Rearr... Non Hodgkin Lym... Leukemia Non Small Cell ... Cholangiocarcin... Glioblastoma Central Nervous... Melanoma Urothelial Carc... Bladder Cancer Ovarian Cancer Endometrial Can... Testicular Canc... Breast Cancer COVID Myelofibrosis Myeloproliferat... Myeloproliferat... Follicular Lymp... Mantle Cell Lym... Marginal Zone L... Myelodysplastic... | Clinical Trial ... | - | Massive Bio, Inc. | |
| Somatic Mosaicism in Twins Discordant for Childhood Cancer | NCT06054295 | Pediatric Centr... Central Nervous... Discordant Twin Somatic Mutatio... | Biospecimen col... Questionnaire A... | - 18 Years | Children's Oncology Group | |
| Carboplatin, Vincristine, and Temozolomide in Treating Children With Progressive and/or Symptomatic Low-Grade Glioma | NCT00077207 | Brain Tumor Central Nervous... | carboplatin temozolomide vincristine sul... | - 10 Years | Children's Oncology Group | |
| Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System | NCT04743310 | Central Nervous... | tozuleristide Canvas imaging ... Surgical resect... | 18 Years - | Cedars-Sinai Medical Center | |
| Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations | NCT05267106 | Glioblastoma Adult-type Diff... | Pemigatinib | 18 Years - 99 Years | Incyte Corporation | |
| National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry | NCT04351035 | Tumors, Central... Pediatric Brain... Malignant Brain... Benign Brain Tu... | Tumour resectio... | - 18 Years | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | |
| High-Dose Chemotherapy Plus Autologous Stem Cell Transplantation Compared With Intermediate-Dose Chemotherapy Plus Autologous Stem Cell Transplantation With or Without Isotretinoin in Treating Young Patients With Recurrent High-Grade Gliomas | NCT00078988 | Brain Tumor Central Nervous... | filgrastim carboplatin etoposide isotretinoin thiotepa autologous bone... peripheral bloo... | - 20 Years | Children's Oncology Group | |
| Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment | NCT02932280 | Solid Tumor Central Nervous... Lymphoma Leukemia | Neratinib | 3 Years - 21 Years | Memorial Sloan Kettering Cancer Center | |
| Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma | NCT00006024 | Brain Tumor Central Nervous... | lomustine temozolomide | 3 Years - 21 Years | Children's Oncology Group | |
| A Study of Avutometinib for People With Solid Tumor Cancers | NCT06104488 | Refractory Canc... CNS Tumors CNS Tumor, Adul... CNS Tumor, Chil... MAP Kinase Fami... NF1 Plexiform Neuro... Low-grade Gliom... Optic Pathway G... Neuroblastoma Primary Brain T... Solid Tumor Solid Tumor, Ad... Solid Carcinoma Central Nervous... | Avutometinib | 3 Years - 30 Years | Memorial Sloan Kettering Cancer Center | |
| Safety and Dose Finding Study of Neratinib in Children and Young Adults With Cancer That Has Returned or Not Responded to Treatment | NCT02932280 | Solid Tumor Central Nervous... Lymphoma Leukemia | Neratinib | 3 Years - 21 Years | Memorial Sloan Kettering Cancer Center | |
| Dendritic Cell-based Immunotherapy for Advanced Solid Tumours of Children and Young Adults | NCT02496520 | Sarcoma Central Nervous... | dendritic cells Surgery as need... Chemotherapy as... Radiation thera... | 3 Years - 40 Years | Clinica Universidad de Navarra, Universidad de Navarra | |
| Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours | NCT06363201 | Advanced Cancer Advanced Solid ... Lymphoma, Hodgk... Central Nervous... Sarcoma Germ Cell Tumor Pediatric Cance... | Ocoxin Oral sol... | 7 Years - 18 Years | Catalysis SL | |
| Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours | NCT06363201 | Advanced Cancer Advanced Solid ... Lymphoma, Hodgk... Central Nervous... Sarcoma Germ Cell Tumor Pediatric Cance... | Ocoxin Oral sol... | 7 Years - 18 Years | Catalysis SL | |
| Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors | NCT00002594 | Brain Tumor Central Nervous... | Sargramostim cyclophosphamid... melphalan autologous bone... bone marrow abl... peripheral bloo... | 2 Years - 25 Years | Children's Oncology Group | |
| Study of BLZ-100 in Pediatric Subjects With CNS Tumors | NCT02462629 | Central Nervous... | BLZ-100 | 1 Month - 30 Years | Blaze Bioscience Inc. | |
| Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors | NCT01445288 | Diffuse Intrins... PNET Ependymoma Germinoma Medulloblastoma | 1 Month - 21 Years | National Institutes of Health Clinical Center (CC) | ||
| Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations | NCT05267106 | Glioblastoma Adult-type Diff... | Pemigatinib | 18 Years - 99 Years | Incyte Corporation | |
| Radiation Therapy in Treating Young Patients With Gliomas | NCT00238264 | Brain Tumor Central Nervous... | radiation thera... | 3 Years - 20 Years | Children's Oncology Group | |
| Brain Slice Explants to Predict Drug Response in Brain Tumors | NCT05978557 | Central Nervous... | Biospecimen col... | - | UNC Lineberger Comprehensive Cancer Center | |
| ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors | NCT04732065 | Diffuse Midline... Glioblastoma Recurrent Epend... Recurrent Malig... Spinal Cord Gli... World Health Or... CNS Tumor Central Nervous... | ONC206 Standard of Car... Optional Proton... | 2 Years - 21 Years | University of California, San Francisco | |
| Radiation Therapy Compared With Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Primary Central Nervous System (CNS) Germ Cell Tumor | NCT00085098 | Brain Tumor Central Nervous... | filgrastim carboplatin cisplatin cyclophosphamid... etoposide radiation thera... | 3 Years - 25 Years | Children's Oncology Group | |
| Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas System | NCT04743310 | Central Nervous... | tozuleristide Canvas imaging ... Surgical resect... | 18 Years - | Cedars-Sinai Medical Center | |
| Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours | NCT06363201 | Advanced Cancer Advanced Solid ... Lymphoma, Hodgk... Central Nervous... Sarcoma Germ Cell Tumor Pediatric Cance... | Ocoxin Oral sol... | 7 Years - 18 Years | Catalysis SL | |
| Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma | NCT04977375 | Glioblastoma Mu... | Pembrolizumab Stereotactic Ra... Surgical Resect... | 18 Years - | Cedars-Sinai Medical Center | |
| Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy | NCT00716976 | Brain Tumor Central Nervous... Childhood Germ ... Extragonadal Ge... Liver Cancer Neuroblastoma Ototoxicity Ovarian Cancer Sarcoma | sodium thiosulf... examination | 1 Year - 18 Years | Children's Oncology Group | |
| Temozolomide Plus Lomustine Followed by Radiation Therapy in Treating Patients With High-Grade Malignant Glioma | NCT00006024 | Brain Tumor Central Nervous... | lomustine temozolomide | 3 Years - 21 Years | Children's Oncology Group | |
| National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry | NCT04351035 | Tumors, Central... Pediatric Brain... Malignant Brain... Benign Brain Tu... | Tumour resectio... | - 18 Years | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | |
| Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO) | NCT03496402 | Neuroblastoma Rhabdomyosarcom... Ewing Sarcoma F... Osteosarcoma Leukemia Central Nervous... | Sampling on blo... | 1 Year - 25 Years | Institut Curie | |
| Combination Chemotherapy Followed by Bone Marrow and/or Peripheral Stem Cell Transplantation in Treating Patients With Recurrent Medulloblastoma or CNS Germ Cell Tumors | NCT00002594 | Brain Tumor Central Nervous... | Sargramostim cyclophosphamid... melphalan autologous bone... bone marrow abl... peripheral bloo... | 2 Years - 25 Years | Children's Oncology Group | |
| Observation or Radiation Therapy and/or Chemotherapy and Second Surgery in Treating Children Who Have Undergone Surgery for Ependymoma | NCT00027846 | Brain Tumor Central Nervous... | filgrastim carboplatin cyclophosphamid... etoposide vincristine sul... radiation thera... Mesna therapeutic con... | 1 Year - 21 Years | Children's Oncology Group | |
| Tissue Collection for Drug Screening and Bioanalysis | NCT04852354 | Pediatric Centr... Central Nervous... | - | Weill Medical College of Cornell University | ||
| Study of BLZ-100 in Pediatric Subjects With CNS Tumors | NCT02462629 | Central Nervous... | BLZ-100 | 1 Month - 30 Years | Blaze Bioscience Inc. | |
| Integrated Cancer Repository for Cancer Research | NCT02012699 | Pancreatic Canc... Thyroid Cancer Lung Cancer Esophageal Canc... Thymus Cancer Colon Cancer Rectal Cancer Gastrointestina... Anal Cancer Bile Duct Cance... Duodenal Cancer Gallbladder Can... Gastric Cancer Liver Cancer Small Intestine... Peritoneal Surf... Familial Adenom... Lynch Syndrome Bladder Cancer Kidney Cancer Penile Cancer Prostate Cancer Testicular Canc... Ureter Cancer Urethral Cancer Hypopharyngeal ... Laryngeal Cance... Lip Cancer Oral Cavity Can... Nasopharyngeal ... Oropharyngeal C... Paranasal Sinus... Nasal Cavity Ca... Salivary Gland ... Skin Cancer Central Nervous... Central Nervous... Mesothelioma Breast Cancer Leukemia Melanoma Sarcoma Unknown Primary... Multiple Myelom... Ovarian Cancer Endometrial Can... Vaginal Cancer Neuroendocrine ... Plasma Cell Dys... Healthy Control | 19 Years - 110 Years | University of Nebraska |
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