Neoplasms

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All Conditions

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Rectal Neoplasms

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Genital Diseases

Genital Diseases, Male

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Female Urogenital Diseases and Pregnancy Complications

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Adjuvants, Anesthesia

Analgesics

Central Nervous System Depressants

All Drugs and Chemicals

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Gastrointestinal Agents

Fentanyl

Droperidol

Droperidol 1.25 mg and fentanyl 0.025 mg (diluted with normal saline up to 5ml) is to be administrated intravenously 30 minutes before the end of the procedure.

The same volume of normal saline is to be administrated intravenously 30 minutes before the end of the procedure.

low-dose neuroleptanalgesia

Placebo

Diansan Su, Doctor

Zhenling Huang, Doctor

Xiao Zhang, MS

Cuixia Song, BS

Postoperative delirium（POD）is a common complication that can directly affect important clinical outcomes, and exert an enormous burden on patients, their families, hospitals, and public resources. In order to evaluate whether an intraoperative administration of low-dose neuroleptanalgesia reduces postoperative delirium, droperidol 1.25 mg and fentanyl 0.025 mg or normal saline is used by intravenous injection 30 minutes before the end of the operation, in elderly patients with non-cardiac major surgery under general anesthesia. The efficiency and safety of neuroleptanalgesia on the incidence of POD would be evaluated in elderly patients.

Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients

Low-dose Neuroleptanalgesia Reduce the Occurrences of Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Major Surgery : a Randomized Controlled Trial

This outcome will be measured using a numeric rating scale from 1 ( dissatisfaction ) to 3 (very satisfied)

Shanghai 8th People's Hospital

RenJi Hospital

Herbal and Botanical

Cola

Intervention: Surgery: laparoscopic sigmoid resection without fast track postoperative care

Intervention: Surgery: conventional (open) sigmoid resection without fast track postoperative care

Conventional surgery compared to laparoscopic sigmoid resection

laparoscopic colonic resection

sigmoid resection by laparoscopic surgery

laparoscopic sigmoid resection

Britta Kaltoft, doctor

A blinded randomized trial. Length of hospital stay, nursing hours and recovery after laparoscopic versus open colonic resection without fast track.

CONTEXT: Our preliminary experience (unpublished) indicate that less nursing hours are needed after laparoscopic colon resection without fast track. Length of hospital stay and recovery seems to be reduced as well.

OBJEKTIVE: To compare laparoscopic and open colonic resection concerning nursing hours, length of hospital stay and recovery.

DESIGN, SETTING AND PATIENTS: triple blinded study (Patient, nursing staff and data collector) including 2 x 12 patients needing sigmoid resection due to cancer. Nursing hours, length of hospital stay and recovery (postoperative pain, questionnaire, actigraph ect.)

Length of Hospital Stay, Nursing Hours and Recovery After Laparoscopic Versus Open Colon Resection Without Fast Track

University Hospital, Gentofte, Copenhagen

Doctor Britta Kaltoft

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients	NCT05068180	Stomach Neoplas... Colonic Neoplas... Rectal Neoplasm... Sigmoid Neoplas... Liver Neoplasms Kidney Neoplasm... Urinary Bladder... Prostatic Neopl... Osteoarthropath... Fractures, Bone Gynecologic Can...	low-dose neurol... Placebo	65 Years - 85 Years	RenJi Hospital
Length of Hospital Stay, Nursing Hours and Recovery After Laparoscopic Versus Open Colon Resection Without Fast Track	NCT01127425	Sigmoid Neoplas...	laparoscopic co... laparoscopic si...	40 Years - 90 Years	University Hospital, Gentofte, Copenhagen
Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients	NCT05068180	Stomach Neoplas... Colonic Neoplas... Rectal Neoplasm... Sigmoid Neoplas... Liver Neoplasms Kidney Neoplasm... Urinary Bladder... Prostatic Neopl... Osteoarthropath... Fractures, Bone Gynecologic Can...	low-dose neurol... Placebo	65 Years - 85 Years	RenJi Hospital

Spots Global Cancer Trial Database for sigmoid neoplasms