Spots Global Cancer Trial Database for Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients
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Trial Identification
Brief Title: Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients
Official Title: Low-dose Neuroleptanalgesia Reduce the Occurrences of Postoperative Delirium in Elderly Patients Undergoing Non-cardiac Major Surgery : a Randomized Controlled Trial
Study ID: NCT05068180
Study Description
Brief Summary: Postoperative delirium（POD）is a common complication that can directly affect important clinical outcomes, and exert an enormous burden on patients, their families, hospitals, and public resources. In order to evaluate whether an intraoperative administration of low-dose neuroleptanalgesia reduces postoperative delirium, droperidol 1.25 mg and fentanyl 0.025 mg or normal saline is used by intravenous injection 30 minutes before the end of the operation, in elderly patients with non-cardiac major surgery under general anesthesia. The efficiency and safety of neuroleptanalgesia on the incidence of POD would be evaluated in elderly patients.
Detailed Description:
Eligibility
Minimum Age: 65 Years
Eligible Ages: OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China
Shanghai Eighth People's Hospital, Shanghai, Shanghai, China
Contact Details
Name: Diansan Su, Doctor
Affiliation: RenJi Hospital
Role: STUDY_CHAIR
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