Spots Global Cancer Trial Database for signet ring adenocarcinoma of the rectum

Every month we try and update this database with for signet ring adenocarcinoma of the rectum cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Cetuximab and/or Dasatinib in Patients With Colorectal Cancer and Liver Metastases That Can Be Removed by Surgery	NCT00835679	Liver Metastase... Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IV Colon ... Stage IV Rectal...	cetuximab dasatinib therapeutic con... laboratory biom...	18 Years -	National Cancer Institute (NCI)
Panitumumab and Chemotherapy in Patients With Advanced Colorectal Cancer After Prior Therapy With Bevacizumab	NCT01814501	Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IV Colon ... Stage IV Rectal...	panitumumab irinotecan hydr... fluorouracil leucovorin calc...	18 Years -	Ohio State University Comprehensive Cancer Center
Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer	NCT00002796	Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta...	fluorouracil sodium phenylbu... indomethacin recombinant int...	-	National Cancer Institute (NCI)
Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies	NCT01643499	Acinar Cell Ade... Adenocarcinoma ... Adenocarcinoma ... Adult Primary C... Advanced Adult ... Cholangiocarcin... Cholangiocarcin... Diffuse Adenoca... Duct Cell Adeno... Intestinal Aden... Localized Unres... Metastatic Carc... Metastatic Extr... Mixed Adenocarc... Mucinous Adenoc... Mucinous Adenoc... Newly Diagnosed... Signet Ring Ade... Signet Ring Ade... Stage III Pancr... Stage IIIA Colo... Stage IIIA Gall... Stage IIIA Gast... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Gall... Stage IIIB Gast... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Gast... Stage IIIC Rect... Stage IV Gastri... Stage IV Pancre... Stage IVA Colon... Stage IVA Gallb... Stage IVA Recta... Stage IVB Colon... Stage IVB Gallb... Stage IVB Recta... Unresectable Ex...	oxaliplatin irinotecan hydr... leucovorin calc... fluorouracil laboratory biom...	18 Years -	University of Chicago
Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer	NCT01871571	Mucinous Adenoc... Signet Ring Ade... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	bevacizumab oxaliplatin leucovorin calc... fluorouracil laboratory biom...	18 Years -	University of Southern California
A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal Cancer	NCT00060411	Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta...	erlotinib hydro... fluorouracil leucovorin calc... oxaliplatin bevacizumab	18 Years -	National Cancer Institute (NCI)
Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer	NCT01923337	Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IIIA Colo... Unspecified Adu...	irinotecan hydr... alisertib	18 Years -	University of California, Davis
Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver	NCT02110953	Liver Metastase... Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta...	irinotecan-elut... hepatic artery ...	18 Years -	Fox Chase Cancer Center
Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer	NCT00002796	Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta...	fluorouracil sodium phenylbu... indomethacin recombinant int...	-	National Cancer Institute (NCI)
Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer	NCT00005036	Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta...	irinotecan hydr... oxaliplatin leucovorin calc... fluorouracil quality-of-life...	18 Years -	National Cancer Institute (NCI)
Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy	NCT01079780	Colorectal Canc...	cetuximab ramucirumab irinotecan hydr...	18 Years -	Eastern Cooperative Oncology Group
Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy	NCT01079780	Colorectal Canc...	cetuximab ramucirumab irinotecan hydr...	18 Years -	Eastern Cooperative Oncology Group
Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer	NCT00005036	Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta...	irinotecan hydr... oxaliplatin leucovorin calc... fluorouracil quality-of-life...	18 Years -	National Cancer Institute (NCI)
Ziv-Aflibercept Followed by Ziv-Aflibercept, Fluorouracil, and Leucovorin Calcium in Treating Patients With Stage IV Colorectal Cancer	NCT02235324	Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta...	ziv-aflibercept leucovorin calc... fluorouracil laboratory biom...	18 Years -	University of Southern California
Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal Malignancies	NCT01643499	Acinar Cell Ade... Adenocarcinoma ... Adenocarcinoma ... Adult Primary C... Advanced Adult ... Cholangiocarcin... Cholangiocarcin... Diffuse Adenoca... Duct Cell Adeno... Intestinal Aden... Localized Unres... Metastatic Carc... Metastatic Extr... Mixed Adenocarc... Mucinous Adenoc... Mucinous Adenoc... Newly Diagnosed... Signet Ring Ade... Signet Ring Ade... Stage III Pancr... Stage IIIA Colo... Stage IIIA Gall... Stage IIIA Gast... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Gall... Stage IIIB Gast... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Gast... Stage IIIC Rect... Stage IV Gastri... Stage IV Pancre... Stage IVA Colon... Stage IVA Gallb... Stage IVA Recta... Stage IVB Colon... Stage IVB Gallb... Stage IVB Recta... Unresectable Ex...	oxaliplatin irinotecan hydr... leucovorin calc... fluorouracil laboratory biom...	18 Years -	University of Chicago
Cholecalciferol(25-[OH]-Vitamin D) in Treating Patients With Colorectal Cancer	NCT01403103	Mucinous Adenoc... Mucinous Adenoc... Signet Ring Ade... Signet Ring Ade... Stage I Colon C... Stage I Rectal ...	cholecalciferol biopsy protein express... enzyme-linked i... laboratory biom... reverse transcr...	18 Years -	Case Comprehensive Cancer Center
Cholecalciferol(25-[OH]-Vitamin D) in Treating Patients With Colorectal Cancer	NCT01403103	Mucinous Adenoc... Mucinous Adenoc... Signet Ring Ade... Signet Ring Ade... Stage I Colon C... Stage I Rectal ...	cholecalciferol biopsy protein express... enzyme-linked i... laboratory biom... reverse transcr...	18 Years -	Case Comprehensive Cancer Center
Gene Therapy in Treating Patients With Cancer	NCT00004178	Cancer	therapeutic aut...	18 Years -	Roger Williams Medical Center
Chemoembolization Using Irinotecan in Treating Patients With Liver Metastases From Metastatic Colon or Rectal Cancer	NCT01285102	Liver Metastase... Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IV Colon ... Stage IV Rectal...	irinotecan-elut... hepatic artery ...	18 Years -	Fox Chase Cancer Center
CPI-613 and Fluorouracil in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed by Surgery	NCT02232152	Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IIIA Colo... Stage IIIA Rect... Stage IIIB Colo... Stage IIIB Rect... Stage IIIC Colo... Stage IIIC Rect... Stage IVA Colon... Stage IVA Recta... Stage IVB Colon... Stage IVB Recta...	6,8-bis(benzylt... fluorouracil pharmacological... laboratory biom...	18 Years -	Wake Forest University Health Sciences
Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation	NCT02132858	Mucinous Adenoc... Recurrent Recta... Signet Ring Ade... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	cytology specim... laboratory biom...	18 Years -	Fox Chase Cancer Center
Bevacizumab, Fluorouracil, Leucovorin Calcium, and Oxaliplatin Before Surgery in Treating Patients With Stage II-III Rectal Cancer	NCT01871571	Mucinous Adenoc... Signet Ring Ade... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	bevacizumab oxaliplatin leucovorin calc... fluorouracil laboratory biom...	18 Years -	University of Southern California
Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Locally Advanced Rectal Cancer	NCT00003799	Adenocarcinoma ... Mucinous Adenoc... Signet Ring Ade... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	fluorouracil oxaliplatin radiation thera... leucovorin calc... therapeutic con...	18 Years -	National Cancer Institute (NCI)
Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer	NCT02270606	Mucinous Adenoc... Recurrent Recta... Signet Ring Ade... Rectal Adenocar... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect...	intensity-modul... fluorouracil oxaliplatin leucovorin calc... therapeutic con...	18 Years -	Virginia Commonwealth University
Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer	NCT01652196	Mucinous Adenoc... Mucinous Adenoc... Signet Ring Ade... Signet Ring Ade... Stage IV Colon ... Stage IV Rectal...	aflibercept oxaliplatin leucovorin fluorouracil Correlative Stu... DCE MRI f18FDG-PET PET (positron e...	18 Years -	Ohio State University Comprehensive Cancer Center
Gefitinib and Combination Chemotherapy in Treating Patients With Advanced or Recurrent Colorectal Cancer	NCT00052585	Adenocarcinoma ... Adenocarcinoma ... Mucinous Adenoc... Mucinous Adenoc... Recurrent Colon... Recurrent Recta... Signet Ring Ade... Signet Ring Ade... Stage IV Colon ... Stage IV Rectal...	irinotecan hydr... gefitinib leucovorin calc... fluorouracil	18 Years -	National Cancer Institute (NCI)
Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer	NCT01652196	Mucinous Adenoc... Mucinous Adenoc... Signet Ring Ade... Signet Ring Ade... Stage IV Colon ... Stage IV Rectal...	aflibercept oxaliplatin leucovorin fluorouracil Correlative Stu... DCE MRI f18FDG-PET PET (positron e...	18 Years -	Ohio State University Comprehensive Cancer Center

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