Spots Global Cancer Trial Database for aflibercept
Every month we try and update this database with for aflibercept cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Trial in Metastatic Colorectal Cancer With FOLFIRI Plus Aflibercept as First Line Treatment | NCT02624726 | Metastatic Colo... | 5 Fluorouracil Leucovorin Irinotecan Aflibercept | 18 Years - | Hellenic Oncology Research Group | |
| Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer | NCT02340949 | Rectal Cancer | Aflibercept 5-Fluoruracil Oxaliplatin Leucovorin | 18 Years - 69 Years | Grupo Espanol Multidisciplinario del Cancer Digestivo | |
| PERMAD: Personalized Marker-driven Early Switch to Aflibercept in Patients With Metastatic Colorectal Cancer | NCT02331927 | Metastatic Colo... | Aflibercept | 18 Years - | University of Ulm | |
| Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer | NCT02340949 | Rectal Cancer | Aflibercept 5-Fluoruracil Oxaliplatin Leucovorin | 18 Years - 69 Years | Grupo Espanol Multidisciplinario del Cancer Digestivo | |
| Aflibercept and 5-FU vs. FOLFOX as 1st Line Treatment for Elderly or Frail Elderly Patients With Met. Colorectal Cancer | NCT03530267 | Colorectal Canc... | Aflibercept + m... mFOLFOX7 | 70 Years - | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | |
| mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer | NCT03043729 | Rectal Cancer Rectosigmoid Ca... | Oxaliplatin 5-FU Leucovorin Aflibercept | 18 Years - | AIO-Studien-gGmbH | |
| mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer | NCT03043729 | Rectal Cancer Rectosigmoid Ca... | Oxaliplatin 5-FU Leucovorin Aflibercept | 18 Years - | AIO-Studien-gGmbH | |
| Aflibercept in Combination With Docetaxel in Metastatic Androgen Independent Prostate Cancer | NCT00519285 | Prostatic Neopl... Neoplasm Metast... | Aflibercept Placebo (for af... Docetaxel Prednisone or P... | 18 Years - | Sanofi | |
| VEGF Trap and Docetaxel in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer | NCT00436501 | Fallopian Tube ... Malignant Tumor... Recurrent Ovari... | docetaxel ziv-aflibercept laboratory biom... pharmacological... | 18 Years - | National Cancer Institute (NCI) | |
| VEGF Trap and Docetaxel in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer | NCT00436501 | Fallopian Tube ... Malignant Tumor... Recurrent Ovari... | docetaxel ziv-aflibercept laboratory biom... pharmacological... | 18 Years - | National Cancer Institute (NCI) | |
| Standard Chemotherapy vs Immunotherapie in 2nd Line Treatment of MSI Colorectal Mestastatic Cancer | NCT03186326 | Metastatic Colo... MSI | FOLFOX regimen FOLFIRI Protoco... Avelumab Panitumumab Cetuximab Bevacizumab Aflibercept | 18 Years - | Federation Francophone de Cancerologie Digestive | |
| Aflibercept +/- LV5FU2 in First Line of Non-resectalbe Metastatic Colorectal Cancers | NCT02384759 | Colorectal Neop... | aflibercept LV5FU2 | 65 Years - | Federation Francophone de Cancerologie Digestive | |
| Colorectal Cancer Metastatic | NCT01670721 | Colorectal Canc... | AFLIBERCEPT Irinotecan Fluorouracil Leucovorin | 18 Years - | Sanofi | |
| Aflibercept and 5-FU vs. FOLFOX as 1st Line Treatment for Elderly or Frail Elderly Patients With Met. Colorectal Cancer | NCT03530267 | Colorectal Canc... | Aflibercept + m... mFOLFOX7 | 70 Years - | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | |
| Colorectal Cancer Metastatic | NCT01670721 | Colorectal Canc... | AFLIBERCEPT Irinotecan Fluorouracil Leucovorin | 18 Years - | Sanofi | |
| A Prospective Observational Cohort Study Evaluating Resection Rate in Patients With Metastatic Colorectal Cancer Treated With Aflibercept in Combination With FOLFIRI - Observatoire résection | NCT05178745 | Metastatic Colo... Colorectal Neop... | Fluorouracil Aflibercept Irinotecan | 18 Years - | Sanofi | |
| Aflibercept and Standard Chemotherapy (R-CHOP) in First Line of Non Hodgkin B-cell Lymphoma | NCT00644124 | Lymphoma, Non-H... | aflibercept | 18 Years - | Sanofi | |
| Study to Identify Biomarkers of Clinical Response to Aflibercept in Patients With Metastatic Colorectal Cancer | NCT02045030 | Metastatic Colo... | aflibercept + F... | 18 Years - | CR-CSSS Champlain-Charles-Le Moyne | |
| Adjuvant Aflibercept for Metastatic Colorectal Cancer | NCT01669720 | Metastatic Colo... | Aflibercept | 18 Years - | Brown University | |
| A Study of Aflibercept in Combination With FOLFIRI in Patients With Second-Line Metastatic Colorectal Cancer in Japan | NCT01882868 | Colorectal Canc... | Aflibercept Levofolinate Irinotecan 5-FU | 20 Years - | Sanofi | |
| Aflibercept +/- LV5FU2 in First Line of Non-resectalbe Metastatic Colorectal Cancers | NCT02384759 | Colorectal Neop... | aflibercept LV5FU2 | 65 Years - | Federation Francophone de Cancerologie Digestive | |
| OPTIMOX-aflibercept as First-line Therapy in Patients With Unresectable Metastatic Colorectal Cancer | NCT01802684 | Unresectable Me... | aflibercept | 18 Years - | GERCOR - Multidisciplinary Oncology Cooperative Group | |
| Clinical Trial of Combination Chemotherapy With Aflibercept in Patients With Advanced Colorectal Cancer | NCT02129257 | Metastatic Colo... | AFLIBERCEPT Irinotecan 5-Fluorouracil Folinic Acid | 18 Years - | Hellenic Cooperative Oncology Group | |
| 5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer | NCT01749956 | Rectal Cancer | Radiation Aflibercept Surgery FOLFOX6 | 18 Years - | SCRI Development Innovations, LLC | |
| Study to Assess the Efficacy and Safety of Treatment With FOLFIRI-aflibercept Compared to Initial Treatment With FOLFIRI-aflibercept (for 6 Cycles) Followed by Maintenance With 5FU-aflibercept, in an Elderly Population With mCRC After Failure of an Oxaliplatin-based Regimen | NCT03279289 | Metastatic Colo... | Aflibercept Irinotecan folinic acid (d... 5Fluorouracil 5-FU | 70 Years - | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) | |
| VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer | NCT00407654 | Recurrent Colon... Recurrent Recta... Stage IV Colon ... Stage IV Rectal... | aflibercept | 18 Years - | National Cancer Institute (NCI) | |
| Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases | NCT01646554 | Colorectal Canc... Liver Metastase... KRAS Mutated Co... | Modified FOLFOX... Aflibercept Surgery | 18 Years - 75 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Aflibercept and Standard Chemotherapy (R-CHOP) in First Line of Non Hodgkin B-cell Lymphoma | NCT00644124 | Lymphoma, Non-H... | aflibercept | 18 Years - | Sanofi | |
| Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers | NCT01843725 | Metastatic Colo... Metastatic Gast... Metastatic Oeso... Metastatic Panc... Metastatic Bili... Metastatic Brea... | capecitabine aflibercept Capecitabine | 18 Years - | Jules Bordet Institute | |
| Study of Aflibercept And Modified FOLFOX6 As First-Line Treatment In Patients With Metastatic Colorectal Cancer | NCT00851084 | Colorectal Neop... Neoplasm Metast... | aflibercept oxaliplatin 5-FU Folinic Acid | 18 Years - | Sanofi | |
| TWICE-IRI: Optimization of Second-line Therapy With Aflibercept, Irinotecan (Day 1 or Day 1,3), 5-Fluorouracile and Folinic Acid in Patients With Metastatic Colorectal Cancer. A Randomized Phase III Study. | NCT04392479 | Cancer Colorect... Metastasis | Aflibercept-FOL... Aflibercept-mFO... | 18 Years - | Hôpital Franco-Britannique-Fondation Cognacq-Jay | |
| Aflibercept for Relapsed Multiple Myeloma | NCT00437034 | Stage II Multip... Stage III Multi... | aflibercept | 18 Years - | National Cancer Institute (NCI) | |
| Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer | NCT01652196 | Mucinous Adenoc... Mucinous Adenoc... Signet Ring Ade... Signet Ring Ade... Stage IV Colon ... Stage IV Rectal... | aflibercept oxaliplatin leucovorin fluorouracil Correlative Stu... DCE MRI f18FDG-PET PET (positron e... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers | NCT01843725 | Metastatic Colo... Metastatic Gast... Metastatic Oeso... Metastatic Panc... Metastatic Bili... Metastatic Brea... | capecitabine aflibercept Capecitabine | 18 Years - | Jules Bordet Institute | |
| A Study of Aflibercept Administered in Combination With Pemetrexed and Cisplatin in Participants With Advanced Carcinoma | NCT00794417 | Advanced Carcin... Non-small Cell ... | Aflibercept Pemetrexed Cisplatin | 18 Years - | Regeneron Pharmaceuticals | |
| A Study of Aflibercept Versus Placebo With FOLFIRI in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin Chemotherapy | NCT01661270 | Colorectal Canc... | Aflibercept Placebo | 18 Years - | Sanofi | |
| A Non-Interventional Follow-Up to the VELOUR Study - Translational Research | NCT01754272 | Metastatic Colo... | 18 Years - | KU Leuven | ||
| Study to Identify Biomarkers of Clinical Response to Aflibercept in Patients With Metastatic Colorectal Cancer | NCT02045030 | Metastatic Colo... | aflibercept + F... | 18 Years - | CR-CSSS Champlain-Charles-Le Moyne | |
| Aflibercept and 5-FU vs. FOLFOX as 1st Line Treatment for Elderly or Frail Elderly Patients With Met. Colorectal Cancer | NCT03530267 | Colorectal Canc... | Aflibercept + m... mFOLFOX7 | 70 Years - | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | |
| Aflibercept and FOLFOX6 Treatment for Previously Untreated Stage IV Colorectal Cancer | NCT01652196 | Mucinous Adenoc... Mucinous Adenoc... Signet Ring Ade... Signet Ring Ade... Stage IV Colon ... Stage IV Rectal... | aflibercept oxaliplatin leucovorin fluorouracil Correlative Stu... DCE MRI f18FDG-PET PET (positron e... | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| A Study of Aflibercept Administered in Combination With Pemetrexed and Cisplatin in Participants With Advanced Carcinoma | NCT00794417 | Advanced Carcin... Non-small Cell ... | Aflibercept Pemetrexed Cisplatin | 18 Years - | Regeneron Pharmaceuticals | |
| Use of Eylea for the Treatment of an Optic Nerve Hemangioma | NCT01714115 | Retinal Hemangi... | Aflibercept | 18 Years - | Vitreous -Retina- Macula Consultants of New York | |
| Study to Assess the Efficacy and Safety of Treatment With FOLFIRI-aflibercept Compared to Initial Treatment With FOLFIRI-aflibercept (for 6 Cycles) Followed by Maintenance With 5FU-aflibercept, in an Elderly Population With mCRC After Failure of an Oxaliplatin-based Regimen | NCT03279289 | Metastatic Colo... | Aflibercept Irinotecan folinic acid (d... 5Fluorouracil 5-FU | 70 Years - | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD) |
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