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Spots Global Cancer Trial Database for A Study of Famitinib in Patients With Advanced Colorectal Cancer

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: A Study of Famitinib in Patients With Advanced Colorectal Cancer

Official Title: A Randomized, Placebo-controlled, Double-blind, Multicenter, Phase IIb Study of Famitinib as Third Line Treatment in Patients With Advanced Colorectal Cancer

Study ID: NCT01762293

Interventions

Famitinib
placebo

Study Description

Brief Summary: Famitinib is a tyrosin-inhibitor agent targeting at c-Kit, VEGFR2, PDGFR, VEGFR3, Flt1 and Flt3, and it's anti-angiogenesis effect has been viewed in preclinical tests. Phase I study has shown that the toxicity is manageable. The purpose of this study is to determine whether Famitinib can improve progression free survival compared with placebo in patients with advanced colorectal cancer who failed in previous at least two lines of chemotherapy.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Cancer center, Sun Yet-sen University, Guangzhou, Guangdong, China

Beijing Cancer Hospital, Peking University, Beijing, , China

Contact Details

Name: Shen Lin, M.D

Affiliation: Beijing Cancer Hospital, Peking University

Role: PRINCIPAL_INVESTIGATOR

Name: Ruihua Xu, M.D

Affiliation: Cancer Center, Sun Yet-sen University

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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