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Brief Title: A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies
Official Title: A Master Protocol for the Multi-Cohort, Phase 1/2 Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies
Study ID: NCT05957367
Brief Summary: This is a Phase 1/2, multicenter, open-label (unless otherwise specified in a combination-specific module) study of DCC-3116 in combination with anticancer therapies. Modules within the master protocol are defined according to different combinations of DCC-3116 with other anticancer agents.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
UCLA Department of Medicine-Hematology/Oncology, Los Angeles, California, United States
Sylvester Comprehensive Cancer Center, Miami, Florida, United States
START Midwest, Grand Rapids, Michigan, United States
Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York, New York, United States
Memorial Sloan Kettering Cancer Center - Main Campus, New York, New York, United States
Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States
Oregon Health & Science University, Portland, Oregon, United States
Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States
Name: Clinical Team
Affiliation: Deciphera Pharmaceuticals LLC
Role: STUDY_DIRECTOR