Spots Global Cancer Trial Database for gist
Every month we try and update this database with for gist cancer trials from around the world to help patients and their families find trials that might be right for them.
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| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Treatment Patterns in Gastrointestinal Stromal Tumors in the Community Oncology Setting | NCT00877045 | Gastrointestina... | 18 Years - | SCRI Development Innovations, LLC | ||
| Efficacy and Safety of Dovitinib in Patients With Gastrointestinal Stromal Tumors Refractory and/or Intolerant to Imatinib | NCT01478373 | Gastrointestina... | Dovitinib (TKI2... | 18 Years - | Novartis | |
| Masitinib in First Line Treatment of Gastro-Intestinal Stromal Tumor (GIST) | NCT00812240 | Gastrointestina... | Masitinib Imatinib | 18 Years - | AB Science | |
| Radiation Therapy as Palliative Treatment of GIST | NCT00515931 | Sarcoma | Radiation thera... | - | University of Helsinki | |
| A Clinical Trial to Compare the Pharmacokinetics of Imatinib Mesylate Tablet 400mg (1 Tablet) and Glivec Film-coated Tablet 100mg (4 Tablets)(Phase I) | NCT01751919 | Chronic Myeloid... Gastrointestina... | Imatinib mesyla... Glivec film-coa... | 20 Years - 50 Years | Dong-A ST Co., Ltd. | |
| Nilotinib in Advanced Gastrointestinal Stromal Tumors (GIST) | NCT00782834 | Gastrointestina... | Nilotinib | 18 Years - | Fox Chase Cancer Center | |
| Liver Transplantation for Unresectable GIST Liver Metastases | NCT04825470 | Liver Diseases Liver Cancer Liver Metastase... Liver Neoplasms Liver Mass Liver Carcinoma Liver Transplan... Liver Transplan... GIST GIST, Malignant Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Metastases to L... Metastatic Live... Metastasis Metastases Liver Transplan... Transplant Onco... | Liver Transplan... | 18 Years - | Hospital Universitario Virgen de la Arrixaca | |
| A Phase 2 Trial of Ponatinib in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumor | NCT01874665 | GIST | Ponatinib | 18 Years - | Takeda | |
| Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World | NCT05381753 | Gastrointestina... | Avapritinib Tyrosine kinase... | 18 Years - | CStone Pharmaceuticals | |
| A Prospective, Randomized, Multicenter, Comparative Study of the Efficacy of Imatinib Resumption Combined With Atezolizumab Versus Imatinib Resumption Alone in Patients With Unresectable Advanced Gastrointestinal Stromal Tumors (GIST) After Failure of Standard Treatments | NCT05152472 | Unresectable Ga... Locally Advance... Metastatic Gast... | Atezolizumab 12... Imatinib 400 MG | 18 Years - | Centre Leon Berard | |
| A Drug-drug Interaction Study of Avapritinib and Midazolam | NCT04908176 | Gastrointestina... GIST Non-resectable ... Recurrent or Un... | Avapritinib midazolam | 18 Years - | Blueprint Medicines Corporation | |
| Preoperative and Postoperative Imatinib Mesylate Study in Patients With c-Kit Positive GIST | NCT00500188 | Gastrointestina... | Imatinib Mesyla... | - | M.D. Anderson Cancer Center | |
| Study of AMN107 With Imatinib in Gastrointestinal Stromal Tumors (GIST) | NCT00135005 | Gastrointestina... | AMN107, STI571 | 18 Years - | Novartis | |
| Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas | NCT03715933 | Solid Tumors Malignant Pleur... Gastric Adenoca... Colorectal Aden... Sarcoma Pancreatic Aden... Ewing Sarcoma Chondrosarcoma GIST SDH-deficient S... | INBRX-109 Carboplatin Cisplatin Pemetrexed 5-fluorouracil Irinotecan Temozolomide | 12 Years - 85 Years | Inhibrx Biosciences, Inc | |
| A Study to Evaluate the Safety of Intuvax Administered Intra-tumorally in Patients With Gastrointestinal Stromal Tumors | NCT02686944 | Gastrointestina... | Intuvax (ilixad... | 18 Years - | Mendus | |
| Liver Transplantation for Unresectable GIST Liver Metastases | NCT04825470 | Liver Diseases Liver Cancer Liver Metastase... Liver Neoplasms Liver Mass Liver Carcinoma Liver Transplan... Liver Transplan... GIST GIST, Malignant Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Metastases to L... Metastatic Live... Metastasis Metastases Liver Transplan... Transplant Onco... | Liver Transplan... | 18 Years - | Hospital Universitario Virgen de la Arrixaca | |
| A Dose-finding Study of a Combination of Imatinib and BYL719 in the Treatment of 3rd Line GIST Patients | NCT01735968 | 3rd Line GIST | ST571 + BYL719 | 18 Years - | Novartis | |
| Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal Tumors | NCT02015065 | GIST | Vandetanib | 3 Years - 99 Years | National Institutes of Health Clinical Center (CC) | |
| Early Access Program (EAP) for Avapritinib in Patients With Locally Advanced Unresectable or Metastatic GIST | NCT03862885 | GIST | Avapritinib | 16 Years - | Blueprint Medicines Corporation | |
| Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors | NCT01381822 | Advanced Renal ... Gastrointestina... Pancreatic Neur... | TH-302 | 18 Years - | Threshold Pharmaceuticals | |
| (VOYAGER) Study of Avapritinib vs Regorafenib in Patients With Locally Advanced Unresectable or Metastatic GIST | NCT03465722 | GIST | avapritinib regorafenib | 18 Years - | Blueprint Medicines Corporation | |
| Phase II Clinical Study of Imatinib Mesylate in Patients With Malignant Gastrointestinal Stromal Tumors (Extension Study) | NCT00237172 | Gastrointestina... | Imatinib Mesyla... | 20 Years - 74 Years | Novartis | |
| A Study of the Efficacy and Safety of Imatinib Mesylate in Patients With Unresectable or Metastatic Gastrointestinal Stromal Tumors Expressing C-kit Gene | NCT00237185 | Unresectable or... | Imatinib mesyla... | 18 Years - | Novartis | |
| Evaluation of Cognitive Function of Patients With Sunitinib or Sorafenib | NCT01246843 | Metastatic Rena... GIST | 18 Years - | Radboud University Medical Center | ||
| Masitinib in Patients With Gastro-Intestinal Stromal Tumour Resistant to Imatinib | NCT01506336 | Gastro Intestin... | masitinib sunitinib | 18 Years - | AB Science | |
| A Clinical Trial With a New Needle Device Comparing Two Needles for EUS_FNA of Solid Lesions. | NCT02246322 | Pancreatic Canc... Neuroendocrine ... Lymphadenopathi... GIST Gastric Wall Tu... | 25G needle 22G needle | 18 Years - | Istituto Clinico Humanitas | |
| Distress, Medication Adherence and Care Needs in Patients With CML and GIST Receiving Oral Targeted Therapy | NCT03880617 | CML GIST | - | National Taiwan University Hospital | ||
| Study to the Optimal Duration of Therapy With Oral Angiogenesis Inhibitors | NCT00777504 | Renal Cell Carc... Gastrointestina... | usage oral angi... stop oral angio... | 18 Years - | Radboud University Medical Center | |
| Study Comparing 12 Months Versus 36 Months of Imatinib in the Treatment of Gastrointestinal Stromal Tumor (GIST) | NCT00116935 | Sarcoma | imatinib mesyla... imatinib imatinib | 18 Years - | Scandinavian Sarcoma Group | |
| Submucosal Tumor Removal by Endoscopic Excision Therapy | NCT04913077 | Submucosal Tumo... | removal of subm... | 18 Years - 80 Years | Universitätsklinikum Hamburg-Eppendorf | |
| Study of Dose Escalation Versus no Dose Escalation of Imatinib in Metastatic Gastrointestinal Stromal Tumors (GIST) Patients | NCT01031628 | Gastrointestina... | Imatinib mesyla... Imatinib mesyla... Imatinib mesyla... | 18 Years - | Sarcoma Alliance for Research through Collaboration | |
| GIST in Hematopoietic Stem Cell Transplantation/Bone Marrow Transplantation | NCT03959046 | Liquid Tumor Cancer Psychological F... | GIST | 21 Years - 99 Years | Weill Medical College of Cornell University | |
| A Clinical Trial to Compare the Pharmacokinetics of Imatinib Mesylate Tablet 400mg (1 Tablet) and Glivec Film-coated Tablet 100mg (4 Tablets)(Phase I) | NCT01751919 | Chronic Myeloid... Gastrointestina... | Imatinib mesyla... Glivec film-coa... | 20 Years - 50 Years | Dong-A ST Co., Ltd. | |
| SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST | NCT06208748 | Gastrointestina... GIST | Bezuclastinib i... | 18 Years - | Sarcoma Alliance for Research through Collaboration | |
| A Study of THE-630 in Patients With Advanced Gastrointestinal Stromal Tumors (GIST) | NCT05160168 | Gastrointestina... Neoplasms, Conn... Neoplasms, Conn... Neoplasms by Hi... Neoplasms Gastrointestina... Digestive Syste... Digestive Syste... Gastrointestina... | THE-630 | 18 Years - | Theseus Pharmaceuticals | |
| Masitinib in Locally Advanced/Metastatic Gastro-intestinal Stromal Tumour (GIST) | NCT00998751 | Gastro-intestin... | oral masitinib | 18 Years - | AB Science | |
| A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib | NCT05734105 | GIST | Ripretinib Sunitinib | 18 Years - | Deciphera Pharmaceuticals LLC | |
| GIST in Hematopoietic Stem Cell Transplantation/Bone Marrow Transplantation | NCT03959046 | Liquid Tumor Cancer Psychological F... | GIST | 21 Years - 99 Years | Weill Medical College of Cornell University | |
| Masitinib in Patients With Gastro-Intestinal Stromal Tumour Resistant to Imatinib | NCT01506336 | Gastro Intestin... | masitinib sunitinib | 18 Years - | AB Science | |
| Efficacy of Pazopanib in Gastrointestinal Stromal Tumors (GIST) | NCT01323400 | GIST | Pazopanib Best supportive... | 18 Years - 90 Years | Centre Leon Berard | |
| Study to the Optimal Duration of Therapy With Oral Angiogenesis Inhibitors | NCT00777504 | Renal Cell Carc... Gastrointestina... | usage oral angi... stop oral angio... | 18 Years - | Radboud University Medical Center | |
| Entacapone Combination With Imatinib for Treatment of GIST | NCT04006769 | Gastrointestina... | Entacapone Imatinib Mesyla... | 18 Years - | Xiangya Hospital of Central South University | |
| 11C-Acetate PET/CT Non-FDG-Avid Tumors | NCT00687778 | Soft Tissue Sar... Thyroid Cancer Lung Cancer Indolent Lympho... Neuroendocrine ... GIST Uterine Maligna... Carcinoma, Hepa... Carcinoma, Lobu... Teratoma | 18 Years - 90 Years | Tel-Aviv Sourasky Medical Center | ||
| Prospective Database of Gastrointestinal Stromal Cell Tumors (GISTs) | NCT02147145 | Gastrointestina... Foregut Subepit... | 18 Years - | Washington University School of Medicine | ||
| Perifosine + Sunitinib Malate for Patients With Advanced Cancers | NCT00399152 | Renal Cancer GIST | Perifosine Sunitinib Malat... | 18 Years - | AEterna Zentaris | |
| Clinical Registry of nCLE in Masses and Cystic Tumors of the Pancreas, Lymph Nodes, Submucosal Lesions of the GI Tract | NCT01770405 | Pancreatic Cyst Pancreatic Neop... Pancreatic Aden... Pancreatic Canc... Pancreatic Isle... Lymph Node Mass Lymphadenopathy GIST | Endoscopic ultr... | 18 Years - | Mauna Kea Technologies | |
| Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas | NCT03715933 | Solid Tumors Malignant Pleur... Gastric Adenoca... Colorectal Aden... Sarcoma Pancreatic Aden... Ewing Sarcoma Chondrosarcoma GIST SDH-deficient S... | INBRX-109 Carboplatin Cisplatin Pemetrexed 5-fluorouracil Irinotecan Temozolomide | 12 Years - 85 Years | Inhibrx Biosciences, Inc | |
| Current Management of Gastrointestinal Stromal Tumors (GIST) in the Region of Coquimbo | NCT00564265 | Gastrointestina... | Observation | 15 Years - | Cirujanos la Serena | |
| Distress, Medication Adherence and Care Needs in Patients With CML and GIST Receiving Oral Targeted Therapy | NCT03880617 | CML GIST | - | National Taiwan University Hospital | ||
| Tasigna Neoadjuvant Gastrointestinal Stromal Tumor (GIST) | NCT01270893 | Gastrointestina... | Nilotinib | 18 Years - | M.D. Anderson Cancer Center | |
| Study in Low Risk Gastrointestinal Stromal Tumor (GISTs) | NCT04599660 | GIST | Treatment of Lo... | 19 Years - | Italian Sarcoma Group | |
| A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies | NCT05957367 | Colorectal Canc... GIST | DCC-3116 Ripretinib Cetuximab Encorafenib | 18 Years - | Deciphera Pharmaceuticals LLC | |
| Surgery for Locally Unresectable Advanced GISTs Without Metastasis After Imatinib Therapy | NCT01865565 | Gastrointestina... | 18 Years - | Chang Gung Memorial Hospital | ||
| Study to Compare Pathologic Type, NIH and WHO Criteria,and Mechanism of GIST Malignant Transformation | NCT03381053 | Method of Diffe... | Imatinib 400mg | 14 Years - 80 Years | Shanghai Zhongshan Hospital | |
| Evaluation of Patients With Bulky GIST Using Sunitinib | NCT01054911 | Tumor | Sunitinib Surgery | 19 Years - | University of Alabama at Birmingham | |
| Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site | NCT03716089 | GIST of Stomach Gastric Cancer Surgery Complication | Laparoscopic re... | 18 Years - 75 Years | Fujian Medical University | |
| Sorafenib for Imatinib/Sunitinib-failed GIST | NCT01091207 | Gastrointestina... | Sorafenib | 18 Years - | Samsung Medical Center | |
| Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors | NCT01381822 | Advanced Renal ... Gastrointestina... Pancreatic Neur... | TH-302 | 18 Years - | Threshold Pharmaceuticals | |
| Prospective Database of Gastrointestinal Stromal Cell Tumors (GISTs) | NCT02147145 | Gastrointestina... Foregut Subepit... | 18 Years - | Washington University School of Medicine | ||
| Phase I Study of OSI-930 and Erlotinib in Cancer Tumors | NCT00603356 | Advanced Solid ... | OSI-930 and erl... | 18 Years - | Astellas Pharma Inc | |
| NIR Fluorescence Imaging With ICG for the Intraoperative Identification of Gastrointestinal Stromal Cell Tumours | NCT04761172 | GIST | Intraoperative ... | 18 Years - | Leiden University Medical Center | |
| Kinase Genotyping of Gastro Intestinal Stomach Tumors (GISTs) From Patients Enrolled in Pfizer A6181112 Phase IIIb Trial | NCT00640692 | Gastrointestina... | 18 Years - 80 Years | Oregon Health and Science University | ||
| A Study of XmAb®18087 in Subjects With NET and GIST | NCT03411915 | Neuroendocrine ... Gastrointestina... | XmAb18087 | 12 Years - | Xencor, Inc. | |
| EUS-FNA Versus KHB in Diagnostics of Upper Gastrointestinal Submucosal Tumors | NCT02025244 | Other Specified... | Key Hole Biopsy... EUS-FNA | 18 Years - 95 Years | Vitkovice Hospital | |
| A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies | NCT05957367 | GIST | DCC-3116 Ripretinib | 18 Years - | Deciphera Pharmaceuticals LLC | |
| Study of Dose Escalation Versus no Dose Escalation of Imatinib in Metastatic Gastrointestinal Stromal Tumors (GIST) Patients | NCT01031628 | Gastrointestina... | Imatinib mesyla... Imatinib mesyla... Imatinib mesyla... | 18 Years - | Sarcoma Alliance for Research through Collaboration | |
| Dovitinib for Patients With Tumor Pathway Activations Inhibited by Dovitinib | NCT01831726 | Tumor Pathway A... | Dovitinib (TKI2... | 18 Years - 100 Years | Novartis | |
| Comparison of Tumor Efficacy Safety in Laparoscopic Resection of Gastrointestinal Stromal Tumors Between Favorable and Unfavorable Site | NCT03716089 | GIST of Stomach Gastric Cancer Surgery Complication | Laparoscopic re... | 18 Years - 75 Years | Fujian Medical University | |
| Clinical Evaluation of Genetron D842V PCR Kit in GIST Patients | NCT05400018 | GIST Gastrointestina... | - | Genetron Health | ||
| Evaluation of Cognitive Function of Patients With Sunitinib or Sorafenib | NCT01246843 | Metastatic Rena... GIST | 18 Years - | Radboud University Medical Center | ||
| Efficacy of Nilotinib in Adult Patients With Gastrointestinal Stromal Tumors Resistant to Imatinib and Sunitinib. | NCT01289028 | Gastrointestina... | Nilotinib | 18 Years - | Novartis | |
| Nilotinib in Advanced Gastrointestinal Stromal Tumors (GIST) | NCT00782834 | Gastrointestina... | Nilotinib | 18 Years - | Fox Chase Cancer Center | |
| A Clinical Trial With a New Needle Device Comparing Two Needles for EUS_FNA of Solid Lesions. | NCT02246322 | Pancreatic Canc... Neuroendocrine ... Lymphadenopathi... GIST Gastric Wall Tu... | 25G needle 22G needle | 18 Years - | Istituto Clinico Humanitas | |
| A Randomised Trial of Imatinib Alternating With Regorafenib Compared to Imatinib Alone for the First Line Treatment of Advanced Gastrointestinal Stromal Tumour (GIST) | NCT02365441 | Gastrointestina... | Regorafenib imatinib | 18 Years - | Australasian Gastro-Intestinal Trials Group | |
| Jejunoileal vs Gastric GIST in the Era of Imatinib. | NCT03923400 | Disease-free Su... Overall Surviva... Recurrence | 18 Years - | Hospital Universitario Virgen de la Arrixaca | ||
| EUS-FNA Versus KHB in Diagnostics of Upper Gastrointestinal Submucosal Tumors | NCT02025244 | Other Specified... | Key Hole Biopsy... EUS-FNA | 18 Years - 95 Years | Vitkovice Hospital | |
| Study of AMG 706 in Subjects With Advanced Gastrointestinal Stromal Tumors (GISTs) | NCT00089960 | Gastrointestina... | AMG 706 | 18 Years - | Amgen | |
| Masitinib in First Line Treatment of Gastro-Intestinal Stromal Tumor (GIST) | NCT00812240 | Gastrointestina... | Masitinib Imatinib | 18 Years - | AB Science | |
| Post-Marketing Clinical Study of Postoperative Adjuvant Therapy With Imatinib Mesylate in Patients With Gastrointestinal Stromal Tumors (GIST) | NCT00171977 | Gastrointestina... | Imatinib Mesyla... | 20 Years - 74 Years | Novartis | |
| The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology) | NCT03896958 | Cancer, All Typ... Cancer of Liver Cancer of Stoma... Cancer of Head ... Cancer of Rectu... Cancer of Kidne... Cancer of Esoph... Cancer of Colon Cancer Skin Cancer of Cervi... Cancer, Metasta... Cancer of Laryn... Cancer of Neck Cancer of Lung Cancer of Brain... Cancer of Vulva... Cancer of Pancr... Sarcoma GIST Small-cell Lung... Adenocarcinoma ... Cancer of Prost... Cancer, Advance... Adrenal Cancer Testicular Canc... Uterine Cancer Bronchoalveolar... Cancer Unknown ... Glioblastoma Mu... Oligodendroglio... Breast Cancer Renal Cell Carc... Hepatocellular ... Cholangiocarcin... Squamous Cell C... Transitional Ce... Cancer, Other Cancer, Anal Melanoma Cancer, Bile Du... Cancer, Bladder Cancer Cords Vo... Cancers Cell Ne... Cancer Differen... Cancer, Anaplas... | 1 Month - 99 Years | SpeciCare |
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