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Brief Title: LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)
Official Title: Laser Interstitial Thermal Therapy Followed By Hypofractionated Radiation Therapy For Treatment Of Newly Diagnosed High-Grade Gliomas
Study ID: NCT04699773
Brief Summary: The purpose of this study is to evaluate the treatment regimen of using Laser Interstitial Thermal Therapy (LITT) and Hypo-fractionated Radiation Therapy to treat patients with newly diagnosed gliomas.
Detailed Description: Radiation therapy is preferably used as an adjunct to surgery for patients with a newly diagnosed or recurrent glioblastoma. LITT offers an alternative to surgical resection, and due to its minimally invasive nature, does not delay initiating radiation therapy. Another advantage of LITT prior to radiation therapy is the ability to obtain a tissue diagnosis of the tumor prior to initiating radiation therapy.
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Maryland Proton Treatment Center, Baltimore, Maryland, United States
University of Maryland Greenebaum Cancer Center, Baltimore, Maryland, United States
UCH Kaufman Cancer Center, Bel Air, Maryland, United States
Central Maryland Radiation Oncology, Columbia, Maryland, United States
Baltimore Washington Medical Center, Glen Burnie, Maryland, United States