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Brief Title: Concomitant Radiation and Cisplatin With and Without Tirapazamine in Treatment of Advanced Head and Neck Cancer
Official Title: Phase III Randomized Trial of Concomitant Radiation, Cisplatin, and Tirapazamine Versus Concomitant Radiation and Cisplatin in Patients With Advanced Head and Neck Cancer
Study ID: NCT00094081
Brief Summary: The trial will compare the efficacy and safety of concomitant chemoradiation with tirapazamine, cisplatin and radiation versus cisplatin and radiation.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Foundation for Cancer Research and Education, Phoenix, Arizona, United States
Stanford University Medical Center, Palo Alto, California, United States
H-Lee Moffitt Cancer Center and Research, Tampa, Florida, United States
University of Chicago Medical Center, Chicago, Illinois, United States
Johns Hopkins Hospital, Baltimore, Maryland, United States
Harper Hospital, Detroit, Michigan, United States
VA New Jersey Health Care Medical Center, East Orange, New Jersey, United States
University of Rochester Medical Center, Rochester, New York, United States
Medical University of South Carolina, Charleston, South Carolina, United States
Eastern Virginia Medical School, Norfolk, Virginia, United States
Name: ICD CSD
Affiliation: Sanofi
Role: STUDY_DIRECTOR