Spots Global Cancer Trial Database for oral cavity
Every month we try and update this database with for oral cavity cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Prevention of Radiation-induced Severe Oral Mucositis in Oral Cavity, Oropharynx, Hypopharynx, and Cavum Cancer | NCT01066741 | Oropharynx Canc... Hypopharynx Can... | Homeodent® 1.4% Sodium Bic... | 18 Years - 85 Years | Centre Leon Berard | |
| Pembrolizumab in Combination With CRT for LA-SCCHN | NCT02586207 | Head and Neck C... Squamous Cell C... Oral Cavity Can... Oropharynx Canc... Hypopharynx Can... Larynx Cancer Laryngeal Cance... | pembrolizumab (... Cisplatin Radiation | 18 Years - | Sanford Health | |
| Cytological Screening for Early Diagnosis of Precancerous or Cancerous Lesions of Oral Cavity | NCT02604121 | Mouth Neoplasms | Orcellex® Rover... | 20 Years - | University Hospital, Toulouse | |
| ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients | NCT03689712 | Oral Mucositis | GC4419 90mg Placebo | 18 Years - | Galera Therapeutics, Inc. | |
| Concomitant Radiation and Cisplatin With and Without Tirapazamine in Treatment of Advanced Head and Neck Cancer | NCT00094081 | Head and Neck N... | tirapazamine (S... cisplatin Radiation Thera... | 18 Years - | Sanofi | |
| The Head and Neck Tumor Biobank | NCT01644786 | Head and Neck S... | 18 Years - | Maastricht Radiation Oncology | ||
| Post-Operative Adjuvant Concurrent Chemoradiotherapy For High Risk Oral Cavity Squamous Cell Carcinoma Patients | NCT00201383 | Oral Cavity Squamous Cell C... | cisplatin | - | National Health Research Institutes, Taiwan | |
| Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor | NCT00377247 | Primary Advance... Squamous Cell C... | autologous mono... | 37 Years - | University of Pittsburgh | |
| Detecting Lesions in the Oral Cavity With Thermal Imaging | NCT00868725 | Carcinoma, Squa... | no intervention... | - | Sheba Medical Center | |
| Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION) | NCT05386550 | Head and Neck C... | Xevinapant (Deb... IMRT Placebo | 18 Years - | EMD Serono | |
| S0329, Gemcitabine and Paclitaxel in Treating Patients With Persistent, Recurrent, or Metastatic Head and Neck Cancer | NCT00100789 | Head and Neck C... | gemcitabine paclitaxel | 18 Years - | SWOG Cancer Research Network | |
| Evaluation of Efficacy and Mechanisms of an Antiinflammatory Intervention for Chemotherapy Related Mucosal Injury | NCT00031551 | Stomatitis | Etanercept Placebo | 16 Years - | National Institutes of Health Clinical Center (CC) | |
| Study to Evaluate the Natural History of Head and Neck Cancer Precursors in Taiwan | NCT02017288 | Head and Neck N... | 21 Years - 100 Years | National Institutes of Health Clinical Center (CC) | ||
| Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck | NCT02158234 | Squamous Cell C... | Cisplatin Stereotactic Bo... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Spectroscopic Analysis of Tongue Tumor Samples. | NCT05104619 | Mass Spectrosco... Molecular Profi... Surgical Margin... Squamous Cell C... Oral Cavity Tongue | tongue surgery | 18 Years - | Centre Hospitalier Universitaire, Amiens | |
| Contribution of Residual Tumour DNA Testing on the Surgical Bed | NCT05934929 | Squamous Cell C... | Circulating tum... | 18 Years - | Centre Henri Becquerel | |
| Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer | NCT03109873 | Larynx Lip Oral Cavity Pharynx | External Beam R... Metformin Hydro... Placebo | 18 Years - 90 Years | Thomas Jefferson University | |
| Phase III Xevinapant (Debio 1143) and Radiotherapy in Resected LA SCCHN, High Risk, Cisplatin-ineligible Participants (XRAY VISION) | NCT05386550 | Head and Neck C... | Xevinapant (Deb... IMRT Placebo | 18 Years - | EMD Serono | |
| Evaluation of an Active Swallowing Rehabilitation on Quality of Life of Patients Treated by Radiotherapy for Head and Neck Cancer | NCT02892487 | Cancer of Head ... | Swallowing ther... | 18 Years - | Rennes University Hospital | |
| Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck | NCT02158234 | Squamous Cell C... | Cisplatin Stereotactic Bo... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Detecting Lesions in the Oral Cavity With Thermal Imaging | NCT00868725 | Carcinoma, Squa... | no intervention... | - | Sheba Medical Center | |
| Organ Preservation in the Multispeciality Therapy of Stage II-IV Locally Advanced Head and Neck Cancer | NCT01187472 | Head and Neck C... | 59 Years - | University of Chicago | ||
| Clonidine HCl MBT vs. Placebo to Prevent Chemoradiotherapy-Induced Severe Oral Mucositis in Oropharyngeal Cancer. | NCT04648020 | Chemoradiothera... | Clonidine HCl M... Placebo Mucoadh... | 18 Years - | Monopar Therapeutics | |
| Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery | NCT03076281 | Larynx LIP Oral Cavity Pharynx | Metformin Hydro... Doxycycline Metformin +Doxy... | 18 Years - | Thomas Jefferson University | |
| Phase II Trial of Allovectin-7® for Head and Neck Cancer | NCT00050388 | Head and Neck C... Squamous Cell C... Head and Neck N... Carcinoma of th... | Allovectin-7® | 18 Years - | Vical | |
| The Effect of Oral Care Protocol on Prevention of Oral Mucositis in Pediatric Cancer Patients | NCT04586491 | Mucositis Pediatric Cance... Oral Cavity | Oral care proto... | 1 Year - 17 Years | Dokuz Eylul University | |
| Phase II Study of Cetuximab With or Without OSI-906 in Head and Neck Squamous Cell Carcinoma (HNSCC) | NCT01427205 | Head and Neck C... | Cetuximab OSI-906 Placebo | 18 Years - | M.D. Anderson Cancer Center | |
| Organ Preservation in the Multispeciality Therapy of Stage II-IV Locally Advanced Head and Neck Cancer | NCT01187472 | Head and Neck C... | 59 Years - | University of Chicago | ||
| Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery | NCT03076281 | Larynx LIP Oral Cavity Pharynx | Metformin Hydro... Doxycycline Metformin +Doxy... | 18 Years - | Thomas Jefferson University | |
| The Head and Neck Tumor Biobank | NCT01644786 | Head and Neck S... | 18 Years - | Maastricht Radiation Oncology | ||
| Induction Chemo Then Concurrent Chemoradiotherapy With Cetuximab in Locally Advanced Head and Neck Squamous Cell Cancer | NCT01326923 | Head and Neck S... | Cetuximab | 18 Years - | Louisiana State University Health Sciences Center Shreveport | |
| Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer | NCT00101582 | Mucositis Solid Tumors Stomatitis Head and Neck C... Squamous Cell C... | Placebo palifermin cisplatin chemo... Radiotherapy | 18 Years - | Swedish Orphan Biovitrum | |
| Perioperative Gabapentin Use In Head And Neck Mucosal Surgery Patients | NCT02926573 | Head and Neck C... Acute Pain Postoperative P... | Gabapentin Placebo | 18 Years - | Washington University School of Medicine | |
| Adaptive, Image-guided, Intensity-modulated Radiotherapy for Head and Neck Cancer in the Reduced Volumes of Elective Neck | NCT01287390 | Primary Non-ope... Primary Non-ope... Primary Non-ope... Primary Non-ope... | video fluorosco... extra imaging scoring acute t... scoring of late... scoring quality... | 18 Years - | University Hospital, Ghent | |
| A Phase 1 Dose Escalation Study of GC4419 in Combination With Chemoradiation for Squamous Cell Cancer of the Head & Neck | NCT01921426 | Squamous Cell C... Squamous Cell C... | GC4419 | 18 Years - | Galera Therapeutics, Inc. | |
| Chemoprevention Study of Oral Cavity Squamous Cell Carcinoma | NCT00201279 | Oral Cavity Squamous Cell C... | 13-cis Retino A... | 20 Years - 65 Years | National Health Research Institutes, Taiwan | |
| Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer | NCT04590963 | Squamous Cell C... | Monalizumab Cetuximab Placebo | 18 Years - 130 Years | AstraZeneca | |
| A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function Mutations | NCT05199584 | Solid Tumors Wi... | ENV-101 (talade... | 18 Years - | Endeavor Biomedicines, Inc. | |
| Evaluation of an Active Swallowing Rehabilitation on Quality of Life of Patients Treated by Radiotherapy for Head and Neck Cancer | NCT02892487 | Cancer of Head ... | Swallowing ther... | 18 Years - | Rennes University Hospital | |
| Spectroscopic Analysis of Tongue Tumor Samples. | NCT05104619 | Mass Spectrosco... Molecular Profi... Surgical Margin... Squamous Cell C... Oral Cavity Tongue | tongue surgery | 18 Years - | Centre Hospitalier Universitaire, Amiens | |
| Concomitant Radiation and Cisplatin With and Without Tirapazamine in Treatment of Advanced Head and Neck Cancer | NCT00094081 | Head and Neck N... | tirapazamine (S... cisplatin Radiation Thera... | 18 Years - | Sanofi | |
| Post-Operative Adjuvant Concurrent Chemoradiotherapy For High Risk Oral Cavity Squamous Cell Carcinoma Patients | NCT00201383 | Oral Cavity Squamous Cell C... | cisplatin | - | National Health Research Institutes, Taiwan | |
| Interventional Study Collecting Quantitative and Qualitative Data About Patient With Non Treated Cancer | NCT01647477 | Upper Aerodiges... | interview questionnaires | 18 Years - | Centre Oscar Lambret | |
| Enoblituzumab Plus MGA012 or MGD013 in Squamous Cell Carcinoma of the Head and Neck | NCT04129320 | Head and Neck C... Squamous Cell C... | enoblituzumab MGA012 MGD013 | 18 Years - | MacroGenics | |
| S0329, Gemcitabine and Paclitaxel in Treating Patients With Persistent, Recurrent, or Metastatic Head and Neck Cancer | NCT00100789 | Head and Neck C... | gemcitabine paclitaxel | 18 Years - | SWOG Cancer Research Network | |
| Prevention of Radiation-induced Severe Oral Mucositis in Oral Cavity, Oropharynx, Hypopharynx, and Cavum Cancer | NCT01066741 | Oropharynx Canc... Hypopharynx Can... | Homeodent® 1.4% Sodium Bic... | 18 Years - 85 Years | Centre Leon Berard | |
| Contribution of Residual Tumour DNA Testing on the Surgical Bed | NCT05934929 | Squamous Cell C... | Circulating tum... | 18 Years - | Centre Henri Becquerel | |
| Selection Pressure and Evolution Induced by Immune Checkpoint Inhibitors and Other Immunologic Therapies | NCT02724488 | Head and Neck C... Melanoma | 18 Years - | University Health Network, Toronto | ||
| Assessment of Efficacy and Safety of Monalizumab Plus Cetuximab Compared to Placebo Plus Cetuximab in Recurrent or Metastatic Head and Neck Cancer | NCT04590963 | Squamous Cell C... | Monalizumab Cetuximab Placebo | 18 Years - 130 Years | AstraZeneca |
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