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Brief Title: Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial.
Official Title: Effect of Simvastatin and Metformin on Clinical, Endocrine, Metabolic and Endothelial Function of Women With Polycystic Ovary Syndrome: Prospective Randomised Trial
Study ID: NCT00396513
Brief Summary: The purpose of this study is to compare effects of statins (simvastatin) and metformin on clinical (menstrual cycle, excessive hair, skin problems), endocrine (androgens), metabolic (lipids, markers of systemic inflammation), and endothelial function parameters in women with polycystic ovary syndrome (PCOS).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: FEMALE
Healthy Volunteers: No
Division of Infertility and Reproductive Endocrinology, Department of Gynecology and Obstetrics, Poznan, , Poland
Name: Leszek Pawelczyk, MD PhD
Affiliation: Poznan University of Medical Scienses
Role: PRINCIPAL_INVESTIGATOR
Name: Antoni J Duleba, MD
Affiliation: Yale University
Role: STUDY_DIRECTOR