Spots Global Cancer Trial Database for simvastatin
Every month we try and update this database with for simvastatin cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer | NCT04457089 | Recurrent Ovari... Platinum-sensit... | Simvastatin 40m... | 18 Years - | Cedars-Sinai Medical Center | |
| Irinotecan/Cisplatin Plus Simvastatin in Extensive Disease-Small Cell Lung Cancer (ED-SCLC) | NCT00452634 | Small Cell Lung... | Irinotecan Cisplatin Simvastatin | 18 Years - | National Cancer Center, Korea | |
| Phase II Study of Simvastatin Plus Irinotecan, Fluorouracil, and Leucovorin(FOLFIRI) for Metastatic CRC | NCT00313859 | Colorectal Canc... Metastasis | simvastatin | 18 Years - | Samsung Medical Center | |
| Permeability MRI in Cerebral Cavernous Malformations Type 1 in New Mexico: Effects of Statins | NCT01764451 | Cavernous Angio... Cerebral Cavern... Cerebral Cavern... | Simvastatin | 18 Years - | University of New Mexico | |
| Phase II Study of Simvastatin for Relapsed/Refractory Myeloma | NCT01332617 | Myeloma | Simvastatin,Zol... | 18 Years - | University of Louisville | |
| Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients | NCT02161822 | Adenocarcinoma ... | simvastatin | 20 Years - | Samsung Medical Center | |
| Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors | NCT02390843 | Retinoblastoma Clear Cell Sarc... Renal Cell Carc... Rhabdoid Tumor Wilms Tumor Hepatoblastoma Neuroblastoma Germ Cell Tumor... Ewings Sarcoma Non-rhabdomyosa... Osteosarcoma Rhabdomyosarcom... | Simvastatin Cyclophosphamid... Topotecan Myeloid growth ... | 1 Year - 29 Years | Emory University | |
| Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer | NCT04418089 | Breast Cancer Chemotherapy Ef... | Simvastatin 40m... Placebo oral ca... | - | Indonesia University | |
| Simvastatin Effect on Radiation Therapy of Brain Metastases | NCT02104193 | Brain Metastase... | simvastatin in ... radiation thera... | 18 Years - | Ain Shams University | |
| The Effect of Simvastatin on Breast Cancer Cell Growth in Women With Stage I-II Breast Cancer | NCT03454529 | Invasive Breast... Stage I Breast ... Stage IA Breast... Stage IB Breast... Stage II Breast... Stage IIA Breas... Stage IIB Breas... | Laboratory Biom... Simvastatin | 19 Years - | Barbara Ann Karmanos Cancer Institute | |
| Metformin and Simvastatin Use in Bladder Cancer | NCT02360618 | Bladder Cancer | Metformin Simvastatin | 18 Years - 85 Years | London Health Sciences Centre | |
| Gefitinib With or Without Simvastatin in Non-Small Cell Lung Cancer (NSCLC) | NCT00452244 | Lung Cancer | simvastatin gefitinib only | 18 Years - | National Cancer Center, Korea | |
| Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy | NCT04985201 | Small Cell Lung... | Irinotecan Simvastatin | 18 Years - 75 Years | Shanghai Pulmonary Hospital, Shanghai, China | |
| Assessing the Role of "Statin" Therapy and Perioperative Inflammatory Response in Patients Undergoing Major Orthopedic Surgery | NCT00656292 | Perioperative I... | Simvastatin Placebo | 18 Years - 80 Years | Mayo Clinic | |
| A Prevention Trial in Subjects at High Risk for Breast Cancer | NCT01500577 | Breast Cancer | nimesulide Simvastatin Placebo | 18 Years - 65 Years | European Institute of Oncology | |
| Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial. | NCT00396513 | Polycystic Ovar... | Simvastatin Simvastatin and... Metformin | 18 Years - 40 Years | Poznan University of Medical Sciences | |
| Simvastatin in Colorectal Surgery | NCT00994903 | Intestinal Neop... Perioperative C... | Simvastatin Placebo | 18 Years - 90 Years | University of Auckland, New Zealand | |
| Effects of Simvastatin on Biochemical Parameters and Outcome of IVF-ICSI in Pcos Patients | NCT00575601 | Polycystic Ovar... | SIMVASTATIN | 20 Years - 40 Years | Tehran University of Medical Sciences | |
| Simvastatin in Preventing a New Breast Cancer in Women at High Risk for a New Breast Cancer | NCT00334542 | Breast Cancer | simvastatin | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Simvastatin in Preventing a New Breast Cancer in Women at High Risk for a New Breast Cancer | NCT00334542 | Breast Cancer | simvastatin | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Investigation of Simvastatin in Secondary Progressive Multiple Sclerosis | NCT00647348 | Secondary Progr... | Simvastatin Placebo | 18 Years - 65 Years | Imperial College London | |
| Cetuximab and Simvastatin in Treating Patients With Advanced or Metastatic Colorectal Cancer | NCT01190462 | Colorectal Canc... | cetuximab simvastatin laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Simvastatin Therapy in Women With Polycystic Ovary Syndrome. | NCT00365638 | Polycystic Ovar... | simvastatin | 18 Years - 40 Years | Poznan University of Medical Sciences | |
| Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer | NCT06030622 | Pancreatic Canc... | Gemcitabine and... C3 (Metformin, ... | 18 Years - | State University of New York - Downstate Medical Center | |
| Simvastatin as Inhibitor of Cell Adhesion Mediated Drug Resistance in Patients With Refractory Multiple Myeloma. | NCT00399867 | Multiple Myelom... | Simvastatin | 18 Years - | Ludwig-Maximilians - University of Munich | |
| Simvastatin Therapy in Women With Polycystic Ovary Syndrome. | NCT00365638 | Polycystic Ovar... | simvastatin | 18 Years - 40 Years | Poznan University of Medical Sciences | |
| Letrozole With and Without Simvastatin for the Treatment of Stage I-III Hormone Receptor Positive, HER2 Negative Breast Cancer | NCT05464810 | Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... HER2-Negative B... Hormone Recepto... Invasive Breast... | Letrozole Simvastatin | 18 Years - | Emory University | |
| Anti-Platelet and Statin Therapy to Prevent Cancer-Associated Thrombosis | NCT02285738 | Solid Tumor Cancer | Aspirin Simvastatin Observation | 18 Years - | Case Comprehensive Cancer Center | |
| Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer | NCT01441349 | Small Cell Lung... | IP chemotherapy IP chemotherapy... | 18 Years - | National Cancer Center, Korea | |
| Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients | NCT02161822 | Adenocarcinoma ... | simvastatin | 20 Years - | Samsung Medical Center | |
| Combined Simvastatin and Albumin Paclitaxel in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy | NCT04698941 | Small Cell Lung... | Albumin Paclita... Simvastatin | 18 Years - 75 Years | Shanghai Pulmonary Hospital, Shanghai, China | |
| Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis | NCT02968810 | Cirrhosis Hepatocellular ... | Biospecimen Col... Computed Tomogr... Magnetic Resona... Placebo Adminis... Questionnaire A... Simvastatin | 18 Years - | National Cancer Institute (NCI) | |
| Multiple Sclerosis-Simvastatin Trial 2 | NCT03387670 | Secondary Progr... | Simvastatin Placebo | 25 Years - 65 Years | University College, London | |
| Capecitabine Plus Simvastatin in Locally Advanced Rectal Cancer Patients | NCT02161822 | Adenocarcinoma ... | simvastatin | 20 Years - | Samsung Medical Center | |
| Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer | NCT01441349 | Small Cell Lung... | IP chemotherapy IP chemotherapy... | 18 Years - | National Cancer Center, Korea | |
| Phase II Study of Simvastatin in Primary Breast Cancer; Test of Its Potential Selectivity on Basal Subtype Breast Cancer | NCT00807950 | Breast Cancer | Simvastatin | 18 Years - | National University Hospital, Singapore | |
| Simvastatin and Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ or Invasive Breast Cancer | NCT00354640 | Breast Cancer | anastrozole simvastatin pharmacological... adjuvant therap... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy | NCT04985201 | Small Cell Lung... | Irinotecan Simvastatin | 18 Years - 75 Years | Shanghai Pulmonary Hospital, Shanghai, China | |
| Simvastatin and Panitumumab in Treating Patients With Advanced or Metastatic Colorectal Cancer | NCT01110785 | Colorectal Canc... | panitumumab simvastatin laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Simvastatin in Waldenstrom's Macroglobulinemia | NCT00575965 | Waldenstrom's M... | Simvastatin | 18 Years - | Dana-Farber Cancer Institute | |
| Effects of Simvastatin on Uterine Leiomyoma Size | NCT03400826 | Fibroid Uterus Fibroid Tumor Leiomyoma Fibromyoma Leiomyoma, Uter... | Simvastatin 40m... Placebo 40 mg | 18 Years - 55 Years | Johns Hopkins University | |
| Effects of Simvastatin on Biochemical Parameters and Outcome of IVF-ICSI in Pcos Patients | NCT00575601 | Polycystic Ovar... | SIMVASTATIN | 20 Years - 40 Years | Tehran University of Medical Sciences | |
| Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer | NCT04418089 | Breast Cancer Chemotherapy Ef... | Simvastatin 40m... Placebo oral ca... | - | Indonesia University | |
| Effects of Simvastatin on Uterine Leiomyoma Size | NCT03400826 | Fibroid Uterus Fibroid Tumor Leiomyoma Fibromyoma Leiomyoma, Uter... | Simvastatin 40m... Placebo 40 mg | 18 Years - 55 Years | Johns Hopkins University | |
| Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer | NCT06030622 | Pancreatic Canc... | Gemcitabine and... C3 (Metformin, ... | 18 Years - | State University of New York - Downstate Medical Center | |
| The Effect of Simvastatin on Breast Cancer Cell Growth in Women With Stage I-II Breast Cancer | NCT03454529 | Invasive Breast... Stage I Breast ... Stage IA Breast... Stage IB Breast... Stage II Breast... Stage IIA Breas... Stage IIB Breas... | Laboratory Biom... Simvastatin | 19 Years - | Barbara Ann Karmanos Cancer Institute | |
| The Role of Simvastatin in The Epithelial-Mesenchymal Transition Process of Breast Cancer | NCT05550415 | Triple Negative... Chemotherapy Ef... Simvastatin Adv... | Simvastatin 40m... Placebo | 18 Years - | Indonesia University | |
| Phase II Study of Simvastatin for Relapsed/Refractory Myeloma | NCT01332617 | Myeloma | Simvastatin,Zol... | 18 Years - | University of Louisville | |
| Simvastatin and Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ or Invasive Breast Cancer | NCT00354640 | Breast Cancer | anastrozole simvastatin pharmacological... adjuvant therap... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Phase II Study of Simvastatin in Primary Breast Cancer; Test of Its Potential Selectivity on Basal Subtype Breast Cancer | NCT00807950 | Breast Cancer | Simvastatin | 18 Years - | National University Hospital, Singapore | |
| Study of Metformin With Simvastatin for Men With Prostate Carcinoma | NCT01561482 | Prostate Carcin... | Metformin Simvastatin | 18 Years - | Baylor College of Medicine | |
| Safety of Simvastatin in LAM and TSC | NCT02061397 | Lymphangioleiom... Tuberous Sclero... | Simvastatin Sirolimus Oral ... Everolimus Oral... | 18 Years - | University of Pennsylvania | |
| Simvastatin in Colorectal Surgery | NCT00994903 | Intestinal Neop... Perioperative C... | Simvastatin Placebo | 18 Years - 90 Years | University of Auckland, New Zealand | |
| Simvastatin and Metformin Therapy in PCOS Women. Prospective Randomised Trial. | NCT00396513 | Polycystic Ovar... | Simvastatin Simvastatin and... Metformin | 18 Years - 40 Years | Poznan University of Medical Sciences | |
| Simvastatin Therapy in Women With Polycystic Ovary Syndrome. | NCT00365638 | Polycystic Ovar... | simvastatin | 18 Years - 40 Years | Poznan University of Medical Sciences | |
| Anti-Platelet and Statin Therapy to Prevent Cancer-Associated Thrombosis | NCT02285738 | Solid Tumor Cancer | Aspirin Simvastatin Observation | 18 Years - | Case Comprehensive Cancer Center | |
| Simvastatin and Panitumumab in Treating Patients With Advanced or Metastatic Colorectal Cancer | NCT01110785 | Colorectal Canc... | panitumumab simvastatin laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| A Single Arm, Phase II Study of Simvastatin Plus XELOX and Bevacizumab as First-line Chemotherapy in Metastatic Colorectal Cancer Patients | NCT02026583 | Colorectal Canc... | Simvastatin | 20 Years - | Samsung Medical Center | |
| Effect of Aminobiphosphonates and Statins on Circulating Vgamma9Vdelta2-T Cells | NCT01179464 | Bone Metastases... | Aminobiphosphon... Simvastatin | - | Amsterdam UMC, location VUmc | |
| Assessing the Role of "Statin" Therapy and Perioperative Inflammatory Response in Patients Undergoing Major Orthopedic Surgery | NCT00656292 | Perioperative I... | Simvastatin Placebo | 18 Years - 80 Years | Mayo Clinic | |
| Trial of XELIRI/FOLFIRI + Simvastatin Followed by Simvastatin Maintenance in Metastatic Colorectal Cancer | NCT01238094 | Colorectal Canc... | Simvastatin | 18 Years - | Samsung Medical Center | |
| Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors | NCT02390843 | Retinoblastoma Clear Cell Sarc... Renal Cell Carc... Rhabdoid Tumor Wilms Tumor Hepatoblastoma Neuroblastoma Germ Cell Tumor... Ewings Sarcoma Non-rhabdomyosa... Osteosarcoma Rhabdomyosarcom... | Simvastatin Cyclophosphamid... Topotecan Myeloid growth ... | 1 Year - 29 Years | Emory University | |
| Statin Therapy to Reduce Progression in Women With Platinum Sensitive Ovarian Cancer | NCT04457089 | Recurrent Ovari... Platinum-sensit... | Simvastatin 40m... | 18 Years - | Cedars-Sinai Medical Center | |
| BIBW 2992 Plus Simvastatin vs. BIBW 2992 in Previously Treated Patients With Advanced Non-adenocarcinomatous NSCLC | NCT01156545 | Non-small Cell ... | BIBW 2992 simvastatin | 18 Years - | National Cancer Center, Korea | |
| A Phase I Study of High Dose Simvastatin in Patients With Gastrointestinal Tract Cancer Who Failed to Standard Chemotherapy | NCT03086291 | Stomach Cancer | Simvastatin | 20 Years - | Samsung Medical Center | |
| Combined Simvastatin and Irinotecan in Treating ES-SCLC Patients Relapsed From 1st Chemotherapy | NCT04985201 | Small Cell Lung... | Irinotecan Simvastatin | 18 Years - 75 Years | Shanghai Pulmonary Hospital, Shanghai, China | |
| Simvastatin and Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ or Invasive Breast Cancer | NCT00354640 | Breast Cancer | anastrozole simvastatin pharmacological... adjuvant therap... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Anti-Platelet and Statin Therapy to Prevent Cancer-Associated Thrombosis | NCT02285738 | Solid Tumor Cancer | Aspirin Simvastatin Observation | 18 Years - | Case Comprehensive Cancer Center | |
| Gefitinib With or Without Simvastatin in Non-Small Cell Lung Cancer (NSCLC) | NCT00452244 | Lung Cancer | simvastatin gefitinib only | 18 Years - | National Cancer Center, Korea | |
| Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer | NCT06030622 | Pancreatic Canc... | Gemcitabine and... C3 (Metformin, ... | 18 Years - | State University of New York - Downstate Medical Center | |
| Effects of Simvastatin on Biochemical Parameters and Outcome of IVF-ICSI in Pcos Patients | NCT00575601 | Polycystic Ovar... | SIMVASTATIN | 20 Years - 40 Years | Tehran University of Medical Sciences |
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