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Brief Title: The Efficacy of Primary Total Mesorectal Excision (TME) Surgery Versus Neoadjuvant Chemotherapy Combined With TME Surgery in Low-risk Locally Advanced Rectal Cancer
Official Title: TME vs TME+nCT in Low-risk LARC
Study ID: NCT05984485
Brief Summary: Comparative analysis of the clinical efficacy between primary Total Mesorectal Excision (TME) surgery and neoadjuvant chemotherapy combined with TME surgery for low-risk locally advanced rectal cancer. Randomly enrolling eligible patients into either the control group receiving neoadjuvant chemotherapy combined with TME surgery or the experimental group receiving primary TME surgery, and subsequently comparing the clinical outcomes of the two groups
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Daping Hospital, Amy Medeical Univerisity, Chongqing, Chongqing, China
Sun yat-sen University, the Sixth Affiliated Hospital, Guangzhou, Guangdong, China
The First Affiliated Hospital of University of South China, Hengyang, Hunan, China
Shengjing Hospital of China Medical University, Shenyang, Liaoning, China
The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China
The Affiliated Nanchong Central Hospital of North Sichuan Medical College, Nanchong, Sichuan, China
Name: Liang Kang, PhD,MD
Affiliation: Sun yat-sen University, sixth affiliated hospital
Role: PRINCIPAL_INVESTIGATOR