Spots Global Cancer Trial Database for National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry
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Trial Identification
Brief Title: National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry
Official Title: Retrospective, Multi-center Cross-sectional Study on Paediatric Central Nervous Systerm Tumours by CNOG-MC001 Collaborative Group
Study ID: NCT04351035
Interventions
Study Description
Brief Summary: Tumours of central nervous system (CNS) is the most common type of solid tumour in childhood. In China, there is limited epidemiology information. Released data from Chinese CDC did not include types of CNS tumours and geographic contribution. As the Children's Neuro-Oncology Group (CNOG) was established in China in May 2017, it makes studies from multiple centers in children's brain tumors become practical. This retrospective cross-sectional study was aligned on CNOG annual meeting in 2018 and research group was named as CNOG-MC001 (MC, multicenter) collaborative group.
Detailed Description: CNS tumours are mostly seen solid tumours in childhood , as the second common malignancy following leukemia in children. The annual age-standardized incidence rate per 1,000,000 person-years (ASR) of CNS tumour in international children's cancer incidence study is 20-30. In Asia, ASR of paediatric CNS tumours is around 15.0-24.9 in Japan, Korea, Singapore. For Chinese races including mainland of China, Taiwan and Hong Kong, ASRs of paediatric CNS tumour are 15.0, 17.4 and 23.8. In 2017 in Shanghai, Children's Neuro-Oncology Group (CNOG) was found in 5th CSPN (Chinese Society of Pediatric Neurosurgery) / 9th CPNF (China Pediatric Neurosurgery Forum) conference, with 35 founding member institutions and 30 founding observation member institutions in mainland of China. Based on this progress, national wide registry (CNOG-MC001) was settled to obtain basic information about CNS tumour cases, combined with available epidemiology data from publications to assess current medical situation on paediatric CNS tumours in China. The protocol of CNOG-MC001 was aligned by CSPN and CNOG member institutions in CNOG annual meeting in 2018 and the study ofiicially started right after the meeting on 20181027. The first step of this study is a national wide pre-survey to all 35 CNOG member institutions and other 22 CSPN members. The pre-survey data sheet included number of annual surgically treated paediatric CNS tumour cases (age ranging from 0 to 18 years old, classified by WHO Classification of Tumours of the Central Nervous System 2016 version), to assess the proper sites to be involved in this study. After retrieving the pre-survey results, large-scale, detailed case data sheets will be sent to participating institutions as members of CNOG-MC001 collaborative group.
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Anhui Provincial Children's Hospital, Hefei, Anhui, China
Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China
Children's Hospital of Chongqing Medical University, Chongqing, Chongqing, China
the First Hospital Affiliated To Army Medical University, Chongqing, Chongqing, China
Army Medical Center of PLA, Chongqing, Chongqing, China
the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China
900 Hospital of the Joint Logistics Team of PLA, Fuzhou, Fujian, China
Lanzhou University Second Hospital, Lanzhou, Gansu, China
Guangdong 999 Brain Hospital, Guangzhou, Guangdong, China
Affiliated Hospital of Guilin Medical University, Guilin, Guangxi Zhuang Autonomous Region, China
Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou, China
the Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China
the First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang, China
Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, China
the Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, China
Renmin Hospital of Wuhan University / Hubei General Hospital, Wuhan, Hubei, China
the Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Hunan, China
the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
Jiangxi Provincial Children's Hospital, Nanchang, Jiangxi, China
the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China
the First Bethune Hospital of Jilin University, Ch'ang-ch'un, Jilin, China
Shengjing Hospital Affiliated to China Medical University, Shenyang, Liaoning, China
the General Hospital of Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, China
Xi'an Children's Hospital, Xi'an, Shaanxi, China
Xijing Hospital of Air Force Military Medical University, Xi'an, Shaanxi, China
Qilu Hospital of Shandong University, Jinan, Shandong, China
Qilu Children's Hospital of Shandong University, Jinan, Shandong, China
Huashan Hospital, Fudan University, Shanghai, Shanghai, China
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai, China
Children's Hospital of Fudan University, Shanghai, Shanghai, China
the Children's Hospital of Shanxi Province, Taiyuan, Shanxi, China
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan, China
Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China
People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang Uygur Autonomous Region, China
Kunming Children's Hospital, Kunming, Yunnan, China
the Children's Hospital, Zhejiang University School of Medicine, Hanzhou, Zhejiang, China
Contact Details
Name: Jie MA, M.D., Ph.D.
Affiliation: Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Role: STUDY_CHAIR
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