Spots Global Cancer Trial Database for pediatric brain tumor
Every month we try and update this database with for pediatric brain tumor cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma | NCT00880061 | Brain Neoplasm Glioma | IL13-PE38QQR | - 17 Years | National Institutes of Health Clinical Center (CC) | |
| Fitness to Aid the Brain and Cognitive Skills | NCT05367076 | Pediatric Brain... Cognitive Impai... | Web-based Aerob... | 6 Years - 18 Years | The Hospital for Sick Children | |
| A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG | NCT03330197 | Pediatric Brain... Diffuse Intrins... | Ad-RTS-hIL-12 Oral Veledimex ... Oral Veledimex ... | 0 Years - 21 Years | Alaunos Therapeutics | |
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma | NCT03615404 | Glioblastoma Malignant Gliom... Medulloblastoma... Pediatric Gliob... Pediatric Brain... Pediatric Brain... | CMV-DCs with GM... Td (tetanus tox... | 0 Years - 35 Years | Duke University | |
| Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma | NCT03478462 | Pediatric Solid... Pediatric Lymph... Pediatric Brain... DIPG Neuroblastoma Ewing Sarcoma Rhabdomyosarcom... Osteosarcoma | CLR 131 | 2 Years - 25 Years | Cellectar Biosciences, Inc. | |
| National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry | NCT04351035 | Tumors, Central... Pediatric Brain... Malignant Brain... Benign Brain Tu... | Tumour resectio... | - 18 Years | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | |
| Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Brain Tumors | NCT05887882 | Pediatric Brain... Recurrent Pedia... Pediatric Supra... | Universal Donor... Implantation | 1 Year - 39 Years | University of California, San Francisco | |
| International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma | NCT02066220 | Brain Tumors | Radiotherapy wi... Reduced-intensi... Radiotherapy wi... Maintenance che... WNT-HR < 16 yea... WNT-HR >= 16 ye... Induction Chemo... SHH-TP53 M0 SHH-TP53 M+ (ge... SHH-TP53 (somat... Vinblastin Main... | 3 Years - 21 Years | Universitätsklinikum Hamburg-Eppendorf | |
| Prospective Cohort Study Depending on the Use of Palliative Care for Advanced Stage of Cancer Patients | NCT03222258 | Stage IV Breast... Stage IV Pancre... Stage IV Colon ... Stage IV Gastri... Stage IV Lung C... Stage IV Liver ... Malignant Hemat... Biliary Cancer ... Pediatric Leuke... Pediatric Lymph... Pediatric Brain... Pediatric Solid... | Early palliativ... Routine hospice... | - | Seoul National University Hospital | |
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma | NCT03615404 | Glioblastoma Malignant Gliom... Medulloblastoma... Pediatric Gliob... Pediatric Brain... Pediatric Brain... | CMV-DCs with GM... Td (tetanus tox... | 0 Years - 35 Years | Duke University | |
| High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study | NCT05740839 | Pediatric Brain... | HIIT Exercise P... Control Group | 18 Years - 39 Years | Dana-Farber Cancer Institute | |
| Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy | NCT06051240 | Cognitive Impai... Cognitive Decli... Radiotherapy Si... Radiotherapy; C... Brain Tumor Memory Impairme... Late Effect of ... | Lithium Placebo | 5 Years - | Region Stockholm | |
| Targeting Pediatric Brain Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i) | NCT05521984 | Pediatric Brain... | Dapagliflozin Carmustine | 6 Years - 21 Years | Washington University School of Medicine | |
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma | NCT03615404 | Glioblastoma Malignant Gliom... Medulloblastoma... Pediatric Gliob... Pediatric Brain... Pediatric Brain... | CMV-DCs with GM... Td (tetanus tox... | 0 Years - 35 Years | Duke University | |
| Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy | NCT06051240 | Cognitive Impai... Cognitive Decli... Radiotherapy Si... Radiotherapy; C... Brain Tumor Memory Impairme... Late Effect of ... | Lithium Placebo | 5 Years - | Region Stockholm | |
| A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma | NCT01878617 | Medulloblastoma | Craniospinal Ir... Cyclophosphamid... Cisplatin Vincristine Vismodegib Pemetrexed Gemcitabine Aerobic Trainin... Neurocognitive ... | 3 Years - 39 Years | St. Jude Children's Research Hospital | |
| Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China | NCT05672043 | Medulloblastoma Central Nervous... Ependymoma Germ Cell Tumor Glioma Brain Tumor, Pe... | 0 Years - 18 Years | Beijing Tiantan Hospital | ||
| Neurofibromatosis Type 1 Brain Tumor Genetic Risk | NCT01707836 | Neurofibromatos... Pediatric Brain... | - 18 Years | Washington University School of Medicine | ||
| Therapeutic Targeting of Sex Differences in Pediatric Brain Tumor Glycolysis | NCT03591861 | Pediatric Brain... | Ketogenic diet BCNU | - 21 Years | Washington University School of Medicine | |
| Visual Telerehabilitation in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain Tumour | NCT06362434 | Hemianopsia | Audiovisual sti... | 10 Years - 40 Years | University Health Network, Toronto | |
| Lithium Treatment to Prevent Cognitive Impairment After Brain Radiotherapy | NCT06051240 | Cognitive Impai... Cognitive Decli... Radiotherapy Si... Radiotherapy; C... Brain Tumor Memory Impairme... Late Effect of ... | Lithium Placebo | 5 Years - | Region Stockholm | |
| Neoepitope-based Personalized Vaccine Approach in Pediatric Patients With Recurrent Brain Tumors | NCT03068832 | Pediatric Brain... | Personalized pe... Poly ICLC Peripheral bloo... | - 21 Years | Washington University School of Medicine | |
| Phase I Study of Marizomib + Panobinostat for Children With DIPG | NCT04341311 | Diffuse Intrins... Pediatric Brain... Pediatric Brain... Pediatric Cance... Pediatric Brain... Diffuse Glioma | Marizomib Panobinostat | - 21 Years | Dana-Farber Cancer Institute | |
| Effects of Music and Maternal Voice on Sedation Depth and Sedative Use During Pediatric Magnetic Resonance Imaging. | NCT04944875 | Pediatric Solid... Pediatric Brain... Pediatric Cance... | Group headphone Group music Group maternal ... | 3 Years - 12 Years | TC Erciyes University | |
| Neurocognitive and Psychosocial Outcomes Among Pediatric Brain Tumor and Blood Cancer Patients | NCT05709522 | Brain Tumor, Pe... Blood Cancer | Neurocognitive ... | 5 Years - 21 Years | Aga Khan University | |
| Neurofibromatosis Type 1 Brain Tumor Genetic Risk | NCT01707836 | Neurofibromatos... Pediatric Brain... | - 18 Years | Washington University School of Medicine | ||
| Prospective Cohort Study Depending on the Use of Palliative Care for Advanced Stage of Cancer Patients | NCT03222258 | Stage IV Breast... Stage IV Pancre... Stage IV Colon ... Stage IV Gastri... Stage IV Lung C... Stage IV Liver ... Malignant Hemat... Biliary Cancer ... Pediatric Leuke... Pediatric Lymph... Pediatric Brain... Pediatric Solid... | Early palliativ... Routine hospice... | - | Seoul National University Hospital | |
| National Wide Cross-sectional Study in Paediatric Central Nervous System Tumours in China -- the CNOG-MC001 Registry | NCT04351035 | Tumors, Central... Pediatric Brain... Malignant Brain... Benign Brain Tu... | Tumour resectio... | - 18 Years | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | |
| High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study | NCT05740839 | Pediatric Brain... | HIIT Exercise P... Control Group | 18 Years - 39 Years | Dana-Farber Cancer Institute | |
| A Study of Ad-RTS-hIL-12 + Veledimex in Pediatric Subjects With Brain Tumors Including DIPG | NCT03330197 | Pediatric Brain... Diffuse Intrins... | Ad-RTS-hIL-12 Oral Veledimex ... Oral Veledimex ... | 0 Years - 21 Years | Alaunos Therapeutics | |
| Targeting Pediatric Brain Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i) | NCT05521984 | Pediatric Brain... | Dapagliflozin Carmustine | 6 Years - 21 Years | Washington University School of Medicine | |
| A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma | NCT01878617 | Medulloblastoma | Craniospinal Ir... Cyclophosphamid... Cisplatin Vincristine Vismodegib Pemetrexed Gemcitabine Aerobic Trainin... Neurocognitive ... | 3 Years - 39 Years | St. Jude Children's Research Hospital | |
| Visual Telerehabilitation in Children, Adolescents and Young Adults With Hemianopsia Consecutive to a Brain Tumour | NCT06362434 | Hemianopsia | Audiovisual sti... | 10 Years - 40 Years | University Health Network, Toronto | |
| Playful Sensorimotor Training in Pediatric Brain Tumor Patients | NCT03334162 | Pediatric Cance... Pediatric Brain... Chemotherapy-in... Sensorimotor Po... | Sensorimotor tr... | 6 Years - 18 Years | University of Basel | |
| Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma | NCT03739372 | Glioma Glioma of Brain Cancer Pediatric Cance... Pediatric Brain... Astrocytoma Glioblastoma Hemispheric | Specialized tum... | - 21 Years | University of California, San Francisco | |
| Neurocognitive and Psychosocial Outcomes Among Pediatric Brain Tumor and Blood Cancer Patients | NCT05709522 | Brain Tumor, Pe... Blood Cancer | Neurocognitive ... | 5 Years - 21 Years | Aga Khan University | |
| High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study | NCT05740839 | Pediatric Brain... | HIIT Exercise P... Control Group | 18 Years - 39 Years | Dana-Farber Cancer Institute | |
| An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-grade Glioma | NCT00880061 | Brain Neoplasm Glioma | IL13-PE38QQR | - 17 Years | National Institutes of Health Clinical Center (CC) | |
| Compassionate Treatment in Children With Brain Tumors With the Cytotron® | NCT03577600 | Pediatric Brain... | QMRT with the C... | 3 Years - 16 Years | Hospital Infantil de Mexico Federico Gomez | |
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma | NCT03615404 | Glioblastoma Malignant Gliom... Medulloblastoma... Pediatric Gliob... Pediatric Brain... Pediatric Brain... | CMV-DCs with GM... Td (tetanus tox... | 0 Years - 35 Years | Duke University |
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