Spots Global Cancer Trial Database for Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo

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Trial Identification

Brief Title: Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo

Official Title: Incidence of Melanoma and Non-melanoma Skin Cancer in People With Vitiligo: A Case-control Study in the United Kingdom, 2009-2020

Study ID: NCT04969419

Conditions

Vitiligo

Melanoma (Skin)

Nonmelanoma Skin Cancer

Squamous Cell Carcinoma

Basal Cell Carcinoma

Actinic Keratoses

Interventions

Exposure of skin cancer of interest

Study Description

Brief Summary: This study examines melanoma and nonmelanoma skin cancer in people diagnosed with vitiligo compared to matched controls.

Detailed Description: For the primary analysis, this study examines the risk of melanoma and nonmelanoma skin cancers: squamous cell carcinoma and basal cell carcinoma in people diagnosed with vitiligo. It also examines actinic keratoses. In secondary analysis, this study examines the prevalence of skin cancer in people diagnosed with vitiligo compared to matched controls. This study also examines whether the susceptibility to melanoma and nonmelanoma skin cancer may vary between different patient subgroups, e.g. ethnicity, those who undergo phototherapy or treatment with the new targeted biologic immunosuppressive therapies.