Spots Global Cancer Trial Database for untreated childhood acute lymphoblastic leukemia

Every month we try and update this database with for untreated childhood acute lymphoblastic leukemia cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Rituximab in Treating Young Patients Who Are Receiving Chemotherapy for B-Cell Non-Hodgkin's Lymphoma or B-Cell Acute Lymphoblastic Leukemia	NCT00324779	Leukemia Lymphoma	rituximab	- 18 Years	National Cancer Institute (NCI)
Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia	NCT00002785	Leukemia	filgrastim asparaginase cyclophosphamid... cyclosporine cytarabine daunorubicin hy... dexamethasone etoposide leucovorin calc... mercaptopurine mesna methotrexate methylprednisol... pegaspargase prednisone therapeutic hyd... vincristine sul... allogeneic bone... low-LET cobalt-... low-LET photon ...	- 1 Year	Children's Oncology Group
Molecular Genetic Lesions and Clinical Outcomes in Children With Acute Lymphoblastic Leukemia	NCT00003291	Leukemia	cytogenetic ana... mutation analys... laboratory biom...	- 17 Years	Children's Oncology Group
Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia	NCT00002756	Leukemia	filgrastim asparaginase cyclophosphamid... cytarabine daunorubicin hy... etoposide leucovorin calc... mercaptopurine methotrexate prednisone therapeutic hyd... vincristine sul...	- 1 Year	Children's Oncology Group
Combination Chemotherapy in Treating Children With Stage III or Stage IV Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia	NCT00003217	Leukemia Lymphoma	filgrastim cyclophosphamid... cytarabine dexamethasone doxorubicin hyd... methotrexate vincristine sul...	- 21 Years	Children's Oncology Group
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia	NCT00002744	Leukemia	asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... mercaptopurine methotrexate pegaspargase prednisone therapeutic hyd... thioguanine vincristine sul... low-LET cobalt-... low-LET photon ...	1 Year - 9 Years	Children's Oncology Group
Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia	NCT00550992	Leukemia	anti-thymocyte ... asparaginase busulfan cyclophosphamid... cyclosporine cytarabine daunorubicin hy... etoposide leucovorin calc... melphalan mercaptopurine methotrexate mitoxantrone hy... pegaspargase prednisolone prednisone therapeutic hyd... thioguanine vincristine sul... allogeneic bone... allogeneic hema... umbilical cord ...	- 1 Year	Dutch Childhood Oncology Group
Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer	NCT00027820	Adult Acute Mye... Childhood Acute... Childhood Acute... Childhood Myelo... Childhood Renal... Chronic Myelomo... Clear Cell Rena... de Novo Myelody... Metastatic Rena... Previously Trea... Progression of ... Recurrent Adult... Recurrent Adult... Recurrent Adult... Recurrent Adult... Recurrent Adult... Recurrent Child... Recurrent Child... Recurrent Child... Recurrent Child... Refractory Anem... Refractory Anem... Refractory Chil... Refractory Chro... Renal Medullary... Type 1 Papillar... Type 2 Papillar... Untreated Adult... Untreated Adult... Untreated Child...	Fludarabine Pho... Total-Body Irra... Peripheral Bloo... Nonmyeloablativ... Cyclosporine Mycophenolate M...	-	Fred Hutchinson Cancer Center
Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia	NCT00437060	Childhood B Acu... Childhood T Acu... Cognitive Side ... Long-Term Effec... Neurotoxicity S... Psychological I... Untreated Child...	Cognitive Asses... Diffusion Tenso... Laboratory Biom... Pharmacological... Psychosocial As...	1 Year - 17 Years	Children's Oncology Group
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia	NCT00002744	Leukemia	asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... mercaptopurine methotrexate pegaspargase prednisone therapeutic hyd... thioguanine vincristine sul... low-LET cobalt-... low-LET photon ...	1 Year - 9 Years	Children's Oncology Group
TITLE:Less Intensive Therapy for Children With Non-Hodgkin's Lymphoma	NCT00002757	Leukemia Lymphoma	filgrastim cyclophosphamid... cytarabine doxorubicin hyd... etoposide methotrexate prednisolone prednisone therapeutic hyd... vincristine sul...	- 20 Years	Children's Oncology Group
Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia	NCT01625143	B-cell Childhoo... Recurrent Child... Untreated Child...	laboratory biom...	- 21 Years	Children's Oncology Group
DNA Analysis of Tissue From Patients With T-Cell Acute Lymphoblastic Leukemia	NCT00899366	Leukemia	microarray anal... mutation analys... immunologic tec...	18 Years - 120 Years	Eastern Cooperative Oncology Group
Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia or Advanced Lymphoblastic Non-Hodgkin's Lymphoma	NCT01230983	Cardiac Toxicit... Leukemia Lymphoma	asparaginase cytarabine dexrazoxane hyd... doxorubicin hyd... leucovorin calc... mercaptopurine methotrexate prednisone therapeutic hyd... vincristine sul... radiation thera...	- 21 Years	Children's Oncology Group
Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia	NCT01625143	B-cell Childhoo... Recurrent Child... Untreated Child...	laboratory biom...	- 21 Years	Children's Oncology Group
Risk-Group Classification of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia	NCT00482352	Untreated Adult... Untreated Child...	laboratory biom...	1 Year - 30 Years	Children's Oncology Group
Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia	NCT00002812	Leukemia	asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... idarubicin mercaptopurine methotrexate pegaspargase prednisone thioguanine vincristine sul... radiation thera...	1 Year - 21 Years	Children's Oncology Group
Alemtuzumab and Combination Chemotherapy in Treating Patients With Untreated Acute Lymphoblastic Leukemia	NCT00061945	Acute Undiffere... B-cell Adult Ac... B-cell Childhoo... L1 Adult Acute ... L1 Childhood Ac... L2 Adult Acute ... L2 Childhood Ac... Philadelphia Ch... Philadelphia Ch... Philadelphia Ch... T-cell Adult Ac... T-cell Childhoo... Untreated Adult... Untreated Child...	allopurinol cyclophosphamid... daunorubicin hy... vincristine sul... dexamethasone asparaginase filgrastim imatinib mesyla... methotrexate cytarabine trimethoprim-su... mercaptopurine leucovorin calc... alemtuzumab acyclovir laboratory biom... pharmacological...	15 Years -	National Cancer Institute (NCI)
Molecular Genetic Lesions and Clinical Outcomes in Children With Acute Lymphoblastic Leukemia	NCT00003291	Leukemia	cytogenetic ana... mutation analys... laboratory biom...	- 17 Years	Children's Oncology Group
Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia	NCT00022126	Leukemia	asparaginase cyclophosphamid... cyclosporine cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... mercaptopurine methotrexate methylprednisol... pegaspargase thioguanine vincristine sul... allogeneic bone... radiation thera...	- 1 Year	Children's Oncology Group
Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphocytic Leukemia	NCT00003671	Leukemia	asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone leucovorin calc... mercaptopurine methotrexate thioguanine vincristine sul...	- 18 Years	Children's Oncology Group
Studying Genes in Samples From Younger Patients With Acute Lymphoblastic Leukemia	NCT01653613	Leukemia	DNA analysis fluorescence in... gene expression... microarray anal... mutation analys... polymorphism an... reverse transcr... laboratory biom...	16 Years - 39 Years	National Cancer Institute (NCI)
Genetic Test in Detecting Minimal Residual Disease in Samples From Younger Patients Registered on the COG-AALL08B1 Trial	NCT01629745	Leukemia	gene expression... flow cytometry laboratory biom...	- 30 Years	Children's Oncology Group
Studying Samples From Patients With T-Cell Acute Lymphoblastic Leukemia	NCT01581528	Leukemia	gene expression... cell culture pr... flow cytometry laboratory biom... metabolic asses...	-	Children's Oncology Group
Helical Tomotherapy, Fludarabine Phosphate, and Melphalan Followed By Allo-HSCT in Hematological Malignancies	NCT00544466	Leukemia Myelodysplastic...	fludarabine pho... melphalan allogeneic hema... intensity-modul...	7 Years -	City of Hope Medical Center
Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia and Diffuse Non-Hodgkin's Lymphoma	NCT00018954	Leukemia Lymphoma	asparaginase cyclophosphamid... cytarabine daunorubicin hy... doxorubicin hyd... etoposide ifosfamide mercaptopurine methotrexate prednisone vincristine sul... conventional su... radiation thera...	-	National Institutes of Health Clinical Center (CC)
Studying Genes in Samples From Younger Patients With Acute Lymphoblastic Leukemia	NCT01653613	Leukemia	DNA analysis fluorescence in... gene expression... microarray anal... mutation analys... polymorphism an... reverse transcr... laboratory biom...	16 Years - 39 Years	National Cancer Institute (NCI)
Hormone Therapy Plus Chemotherapy in Treating Children With Acute Lymphoblastic Leukemia	NCT00003437	Leukemia	asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... mercaptopurine methotrexate pegaspargase prednisolone thioguanine vincristine sul... radiation thera...	1 Year - 18 Years	National Cancer Institute (NCI)
Radiation Therapy to the Head or Intrathecal Chemotherapy Plus High Dose Cytarabine in Preventing CNS Disease in Children With Acute Lymphoblastic Leukemia	NCT00019409	Leukemia	asparaginase cyclophosphamid... cytarabine daunorubicin hy... mercaptopurine methotrexate prednisone therapeutic hyd... vincristine sul... radiation thera...	1 Year - 20 Years	National Institutes of Health Clinical Center (CC)
Risk-Adjusted Combination Chemotherapy in Treating Young Patients With Acute Lymphoblastic Leukemia	NCT00764907	Leukemia	asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... etoposide ifosfamide leucovorin calc... mercaptopurine methotrexate prednisone thioguanine vincristine sul... vindesine	- 18 Years	National Cancer Institute (NCI)
Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma	NCT00003728	Leukemia Lymphoma	asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... etoposide leucovorin calc... mercaptopurine methotrexate methylprednisol... mitoxantrone hy... prednisolone therapeutic hyd... thioguanine vincristine sul... vindesine allogeneic bone... peripheral bloo...	- 17 Years	National Cancer Institute (NCI)
DNA Analysis of Bone Marrow and Blood Samples From Young Patients With Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia	NCT00899652	Leukemia	Southern blotti... chromosomal tra... cytogenetic ana... gene rearrangem... mutation analys...	- 21 Years	Children's Oncology Group
TITLE:Less Intensive Therapy for Children With Non-Hodgkin's Lymphoma	NCT00002757	Leukemia Lymphoma	filgrastim cyclophosphamid... cytarabine doxorubicin hyd... etoposide methotrexate prednisolone prednisone therapeutic hyd... vincristine sul...	- 20 Years	Children's Oncology Group
Studying DNA in Blood and Bone Marrow Samples From Young Patients With Acute Lymphoblastic Leukemia	NCT01016379	Leukemia	DNA analysis biologic sample... laboratory biom...	1 Year - 30 Years	Children's Oncology Group
Growth Factor to Prevent Oral Mucositis in Patients With Hematologic Cancer	NCT00004132	Drug/Agent Toxi... Leukemia Lymphoma Multiple Myelom... Oral Complicati... Radiation Toxic...	filgrastim palifermin cyclophosphamid... etoposide ifosfamide quality-of-life... radiation thera...	12 Years - 65 Years	National Cancer Institute (NCI)
Two Combination Chemotherapy Regimens in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia	NCT00707083	Leukemia	dexamethasone mercaptopurine methotrexate vincristine sul...	- 17 Years	Prince of Wales Hospital, Shatin, Hong Kong
Study of Long-Term Outcomes of Patients With Acute Lymphoblastic Leukemia Who Were Enrolled as Children on Clinical Trials EORTC-58741, EORTC-58831, EORTC-58832, or EORTC-58881 Between 1971 and 1998	NCT01298388	Cancer Survivor Leukemia Long-term Effec...	medical chart r... questionnaire a... study of socioe...	- 17 Years	National Cancer Institute (NCI)
Combination Chemotherapy in Treating Children With Very High Risk Acute Lymphocytic Leukemia	NCT00003783	Leukemia	filgrastim asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone etoposide idarubicin leucovorin calc... mercaptopurine methotrexate prednisone vincristine sul... radiation thera...	- 17 Years	Children's Oncology Group
Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma	NCT00057811	Childhood Burki... Childhood Diffu... Childhood Immun... Stage I Childho... Stage I Childho... Stage II Childh... Stage II Childh... Stage III Child... Stage III Child... Stage IV Childh... Stage IV Childh... Untreated Child...	doxorubicin hyd... cyclophosphamid... methotrexate rasburicase leucovorin calc... prednisone methylprednisol... filgrastim rituximab cytarabine etoposide vincristine sul... hydrocortisone ... laboratory biom...	1 Year - 29 Years	Children's Oncology Group
Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia	NCT00005945	Leukemia	cyclophosphamid... cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... mercaptopurine methotrexate pegaspargase thioguanine vincristine sul... radiation thera...	1 Year - 9 Years	Children's Oncology Group
Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia	NCT00550992	Leukemia	anti-thymocyte ... asparaginase busulfan cyclophosphamid... cyclosporine cytarabine daunorubicin hy... etoposide leucovorin calc... melphalan mercaptopurine methotrexate mitoxantrone hy... pegaspargase prednisolone prednisone therapeutic hyd... thioguanine vincristine sul... allogeneic bone... allogeneic hema... umbilical cord ...	- 1 Year	Dutch Childhood Oncology Group
Studying Body Mass Index in Younger Patients Who Are Receiving Treatment for High-Risk Acute Lymphoblastic Leukemia	NCT00900445	Acute Lymphobla... Untreated Child...	Daunorubicin Hy... Pharmacological... Prednisolone Prednisone Vincristine Sul...	10 Years - 19 Years	Children's Oncology Group
Treosulfan, Fludarabine Phosphate, and Total-Body Irradiation Before Donor Stem Cell Transplant in Treating Patients With High-Risk Acute Myeloid Leukemia, Myelodysplastic Syndrome, Acute Lymphoblastic Leukemia	NCT00860574	Accelerated Pha... Adult Acute Lym... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Blastic Phase C... Childhood Acute... Childhood Acute... Childhood Chron... Childhood Myelo... Chronic Myelomo... de Novo Myelody... Previously Trea... Recurrent Adult... Recurrent Adult... Recurrent Child... Recurrent Child... Secondary Myelo... Untreated Adult... Untreated Child...	treosulfan fludarabine pho... total-body irra... peripheral bloo... tacrolimus allogeneic bone... allogeneic hema... methotrexate	- 60 Years	Fred Hutchinson Cancer Center
DNA Analysis of Tissue From Patients With T-Cell Acute Lymphoblastic Leukemia	NCT00899366	Leukemia	microarray anal... mutation analys... immunologic tec...	18 Years - 120 Years	Eastern Cooperative Oncology Group
Combination Chemotherapy With or Without Donor Bone Marrow Transplantation in Treating Infants With Previously Untreated Acute Lymphoblastic Leukemia	NCT00022126	Leukemia	asparaginase cyclophosphamid... cyclosporine cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... mercaptopurine methotrexate methylprednisol... pegaspargase thioguanine vincristine sul... allogeneic bone... radiation thera...	- 1 Year	Children's Oncology Group
Studying Dexamethasone and Prednisone Sensitivity in Samples From Younger Patients With High-Risk B-Cell Precursor Acute Lymphoblastic Leukemia	NCT01553162	Leukemia	DNA analysis RNA analysis gene expression... laboratory biom...	1 Year - 21 Years	Children's Oncology Group
Comparison of Different Combination Chemotherapy Regimens in Treating Infants With Acute Lymphoblastic Leukemia	NCT00015873	Leukemia	asparaginase cytarabine mercaptopurine methotrexate prednisolone vincristine sul...	- 1 Year	Dutch Childhood Oncology Group
Studying Genes in Samples From Younger Patients With Relapsed Acute Lymphoblastic Leukemia	NCT01625143	B-cell Childhoo... Recurrent Child... Untreated Child...	laboratory biom...	- 21 Years	Children's Oncology Group

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