Spots Global Cancer Trial Database for acute leukemia of ambiguous lineage

Every month we try and update this database with for acute leukemia of ambiguous lineage cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases	NCT06013423	Acute Leukemia ... Acute Lymphobla... Acute Myeloid L... Blastic Plasmac... Hematopoietic a... Mixed Phenotype... Myelodysplastic... Myeloproliferat... Non-Hodgkin Lym... Chronic Myeloid...	Biospecimen Col... Bone Marrow Asp... Cyclophosphamid... Cyclosporine Diagnostic Imag... Echocardiograph... Fludarabine Pho... Multigated Acqu... Mycophenolate M... Survey Administ... Thiotepa Total-Body Irra... Umbilical Cord ...	6 Months - 65 Years	Fred Hutchinson Cancer Center
Venetoclax Basket Trial for High Risk Hematologic Malignancies	NCT05292664	Myelodysplastic... Myelodysplastic... Myelodysplastic... Treatment-Relat... Therapy-Related... Acute Lymphobla... Acute Lymphobla... Lymphoblastic L... Lymphoblastic L... Acute Leukemia ... Acute Leukemia ...	Venetoclax Azacitidine Cytarabine Methotrexate Hydrocortisone Leucovorin Dexamethasone Vincristine Doxorubicin Dexrazoxane Calaspargase Pe... Erwinia asparag...	1 Year - 40 Years	Dana-Farber Cancer Institute
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children	NCT01858740	Accelerated Pha... Acute Biphenoty... Acute Leukemia ... Acute Undiffere... Adult Acute Lym... Adult Acute Mye... Blast Phase Chr... Childhood Acute... Childhood Acute... Chronic Myeloge... Myelodysplastic... Myelodysplastic... Recurrent Adult... Recurrent Adult... Recurrent Child... Recurrent Child... Refractory Adul... Refractory Chil...	Allogeneic Hema... Fludarabine Pho... Laboratory Biom... Methotrexate Peripheral Bloo... T Cell-Depleted... Tacrolimus Thiotepa Total-Body Irra...	- 21 Years	Fred Hutchinson Cancer Center
Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage	NCT04440267	Acute Leukemia ...	vincristine daunorubicin cyclophosphamid... L-Asparaginase prednisone mercaptopurine methotrexate dexamethasone Tyrosine kinase...	14 Years -	Institute of Hematology & Blood Diseases Hospital, China
Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement	NCT02828358	Acute Leukemia ... B Acute Lymphob... Mixed Phenotype...	Azacitidine Cyclophosphamid... Cytarabine Daunorubicin Daunorubicin Hy... Dexamethasone Hydrocortisone ... Laboratory Biom... Leucovorin Leucovorin Calc... Mercaptopurine Methotrexate Pegaspargase Pharmacological... Prednisolone Thioguanine Vincristine Vincristine Sul...	- 364 Days	National Cancer Institute (NCI)
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation	NCT04065399	Acute Myeloid L... Acute Lymphobla... Mixed Lineage A... Mixed Phenotype... Acute Leukemia ...	revumenib cobicistat	30 Days -	Syndax Pharmaceuticals
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD	NCT02220985	Accelerated Pha... Acute Biphenoty... Acute Leukemia ... Acute Undiffere... Allogeneic Hema... Blast Phase Chr... Blastic Plasmac... Childhood Acute... Childhood Acute... Donor Lymphoblastic L... Myelodysplastic... Myelodysplastic... Myelodysplastic... Recurrent Acute... Recurrent Acute... Recurrent Child... Recurrent Child... Recurrent Chron... Refractory Acut... Refractory Acut... Acute Lymphobla... Acute Myeloid L...	Allogeneic Hema... Cyclophosphamid... Fludarabine Pho... Laboratory Biom... Methotrexate Mycophenolate M... Peripheral Bloo... Peripheral Bloo... Tacrolimus Thiotepa Total-Body Irra...	- 60 Years	Fred Hutchinson Cancer Center
First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia	NCT04067336	Advanced Malign... Acute Myeloid L... Mixed Lineage L... Mixed Lineage A... Acute Leukemia ... Mixed Phenotype...	Ziftomenib	18 Years -	Kura Oncology, Inc.
Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial	NCT06355583	Acute Lymphobla... Acute Leukemia ... Chronic Myeloid... Chronic Myelomo... Myelodysplastic... Acute Myeloid L...	EBX-102 Placebo	18 Years -	Imperial College London
Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasm	NCT03012672	Acute Leukemia ... Acute Myeloid L... Myeloid Neoplas...	Cladribine Cytarabine Granulocyte Col... Mitoxantrone Hy... Quality-of-Life... Questionnaire A...	18 Years -	University of Washington
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children	NCT01858740	Accelerated Pha... Acute Biphenoty... Acute Leukemia ... Acute Undiffere... Adult Acute Lym... Adult Acute Mye... Blast Phase Chr... Childhood Acute... Childhood Acute... Chronic Myeloge... Myelodysplastic... Myelodysplastic... Recurrent Adult... Recurrent Adult... Recurrent Child... Recurrent Child... Refractory Adul... Refractory Chil...	Allogeneic Hema... Fludarabine Pho... Laboratory Biom... Methotrexate Peripheral Bloo... T Cell-Depleted... Tacrolimus Thiotepa Total-Body Irra...	- 21 Years	Fred Hutchinson Cancer Center
First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia	NCT04067336	Advanced Malign... Acute Myeloid L... Mixed Lineage L... Mixed Lineage A... Acute Leukemia ... Mixed Phenotype...	Ziftomenib	18 Years -	Kura Oncology, Inc.
Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasm	NCT03012672	Acute Leukemia ... Acute Myeloid L... Myeloid Neoplas...	Cladribine Cytarabine Granulocyte Col... Mitoxantrone Hy... Quality-of-Life... Questionnaire A...	18 Years -	University of Washington
Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia	NCT06177067	Refractory Acut... Relapsed Acute ... Acute Leukemia ...	Revumenib Venetoclax Azacitidine intrathecal (IT... Cytarabine Methotrexate	1 Year - 30 Years	St. Jude Children's Research Hospital
Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage	NCT04440267	Acute Leukemia ...	vincristine daunorubicin cyclophosphamid... L-Asparaginase prednisone mercaptopurine methotrexate dexamethasone Tyrosine kinase...	14 Years -	Institute of Hematology & Blood Diseases Hospital, China
Venetoclax Combined With Azactidine in the Treatment of ALAL	NCT05901974	Acute Leukemia ...	Venetoclax azactidine	15 Years - 65 Years	The First Affiliated Hospital of Soochow University
Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous Lineage	NCT04440267	Acute Leukemia ...	vincristine daunorubicin cyclophosphamid... L-Asparaginase prednisone mercaptopurine methotrexate dexamethasone Tyrosine kinase...	14 Years -	Institute of Hematology & Blood Diseases Hospital, China
Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement	NCT02828358	Acute Leukemia ... B Acute Lymphob... Mixed Phenotype...	Azacitidine Cyclophosphamid... Cytarabine Daunorubicin Daunorubicin Hy... Dexamethasone Hydrocortisone ... Laboratory Biom... Leucovorin Leucovorin Calc... Mercaptopurine Methotrexate Pegaspargase Pharmacological... Prednisolone Thioguanine Vincristine Vincristine Sul...	- 364 Days	National Cancer Institute (NCI)
Venetoclax Basket Trial for High Risk Hematologic Malignancies	NCT05292664	Myelodysplastic... Myelodysplastic... Myelodysplastic... Treatment-Relat... Therapy-Related... Acute Lymphobla... Acute Lymphobla... Lymphoblastic L... Lymphoblastic L... Acute Leukemia ... Acute Leukemia ...	Venetoclax Azacitidine Cytarabine Methotrexate Hydrocortisone Leucovorin Dexamethasone Vincristine Doxorubicin Dexrazoxane Calaspargase Pe... Erwinia asparag...	1 Year - 40 Years	Dana-Farber Cancer Institute
Higher or Lower Dose Cladribine, Cytarabine, and Mitoxantrone in Treating Medically Less Fit Patients With Newly Diagnosed Acute Myeloid Leukemia or Myeloid Neoplasm	NCT03012672	Acute Leukemia ... Acute Myeloid L... Myeloid Neoplas...	Cladribine Cytarabine Granulocyte Col... Mitoxantrone Hy... Quality-of-Life... Questionnaire A...	18 Years -	University of Washington

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