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Spots Global Cancer Trial Database for btk inhibitor

Every month we try and update this database with for btk inhibitor cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell MalignanciesNCT05275504
B-Cell Malignan...
TT-01488
18 Years - TransThera Sciences (Nanjing), Inc.
Acalabrutinib in Combination With R-miniCHOP in Older Adults With Untreated Diffuse Large B-Cell LymphomaNCT05820841
Large B-cell Ly...
Diffuse Large B...
R-miniCHOP + Ac...
R-miniCHOP
61 Years - Universität des Saarlandes
Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell MalignanciesNCT05275504
B-Cell Malignan...
TT-01488
18 Years - TransThera Sciences (Nanjing), Inc.
Bendamustine, Rituximab and Acalabrutinib in Waldenstrom's MacroglobulinemiaNCT04624906
Waldenstrom Mac...
Acalabrutinib
Bendamustine
Rituximab
18 Years - Sunnybrook Health Sciences Centre
A Study of NX-5948 in Adults With Relapsed/Refractory B-cell MalignanciesNCT05131022
Chronic Lymphoc...
Small Lymphocyt...
Diffuse Large B...
Follicular Lymp...
Mantle Cell Lym...
Marginal Zone L...
Waldenstrom Mac...
Primary Central...
NX-5948
18 Years - Nurix Therapeutics, Inc.
Escalating Dose Study in Subjects With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's MacroglobulinemiaNCT01351935
B Cell Non-Hodg...
Chronic Lymphoc...
Waldenstrom Mac...
AVL-292
18 Years - Celgene
Escalating Dose Study in Subjects With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's MacroglobulinemiaNCT01351935
B Cell Non-Hodg...
Chronic Lymphoc...
Waldenstrom Mac...
AVL-292
18 Years - Celgene
Orelabrutinib Combined With Pemetrexed For Relapsed/Refractory Central Nervous System LymphomaNCT05209620
Central Nervous...
ICP-022
Pemetrexed
18 Years - 75 YearsHenan Cancer Hospital
Expanded Access Program for Pirtobrutinib for Participants With B-Cell CancerNCT05172700
Leukemia, Lymph...
Lymphoma, Lymph...
Lymphoma, Mantl...
Waldenstrom Mac...
Ritcher's Trans...
Pirtobrutinib
18 Years - Eli Lilly and Company
LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell MalignanciesNCT05990465
Non Hodgkin Lym...
Diffuse Large B...
Follicular Lymp...
Marginal Zone L...
Mantle Cell Lym...
Burkitt Lymphom...
Pirtobrutinib
LV20.19 CAR T c...
18 Years - 81 YearsMedical College of Wisconsin
Study to Evaluate the Safety and Tolerability of TT-01488 in Patients With B-Cell MalignanciesNCT05275504
B-Cell Malignan...
TT-01488
18 Years - TransThera Sciences (Nanjing), Inc.
Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLLNCT01752426
Leukemia
Heavy Water (2H...
PCI-32765
18 Years - M.D. Anderson Cancer Center
Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell LymphomaNCT04002947
Non-Hodgkin's L...
Diffuse Large B...
DLBCL
NHL
DA-EPOCH
Rituximab
CHOP
Acalabrutinib
18 Years - National Institutes of Health Clinical Center (CC)
Acalabrutinib in Combination With R-miniCHOP in Older Adults With Untreated Diffuse Large B-Cell LymphomaNCT05820841
Large B-cell Ly...
Diffuse Large B...
R-miniCHOP + Ac...
R-miniCHOP
61 Years - Universität des Saarlandes
Ibrutinib With Rituximab in Adults With Waldenström's MacroglobulinemiaNCT02165397
Waldenström's M...
Ibrutinib
Placebo
Rituximab
18 Years - Pharmacyclics LLC.
A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)NCT05023980
Chronic Lymphoc...
Small Lymphocyt...
Pirtobrutinib
Bendamustine
Rituximab
18 Years - Eli Lilly and Company
Bendamustine, Rituximab and Acalabrutinib in Waldenstrom's MacroglobulinemiaNCT04624906
Waldenstrom Mac...
Acalabrutinib
Bendamustine
Rituximab
18 Years - Sunnybrook Health Sciences Centre
Ibrutinib With Rituximab in Adults With Waldenström's MacroglobulinemiaNCT02165397
Waldenström's M...
Ibrutinib
Placebo
Rituximab
18 Years - Pharmacyclics LLC.
A Prospective Clinical Study of BTK Inhibitor, PD-1 and Formustine in the First-line Treatment of Primary Central Nervous System LymphomaNCT04831658
Primary Central...
the dose-escala...
18 Years - 69 YearsZhengzhou University
A Prospective Clinical Study of BTK Inhibitor, PD-1 and Formustine in the First-line Treatment of Primary Central Nervous System LymphomaNCT04831658
Primary Central...
the dose-escala...
18 Years - 69 YearsZhengzhou University
Clinical Study of the Safety and Efficacy of the R/R B-NHL Regimen With BTK Inhibitor+Anti-CD19 CAR-T CellsNCT05744037
B-cell Non Hodg...
regimen with BT...
18 Years - 70 YearsThe Affiliated Hospital of Xuzhou Medical University
A Combination Study of CAR-T Therapy in r/r B-NHLNCT05871684
Diffuse Large B...
BTK inhibitor
PD-1 inhibitor
18 Years - Ruijin Hospital
A Study of Pirtobrutinib (LOXO-305) Versus Bendamustine Plus Rituximab (BR) in Untreated Patients With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)NCT05023980
Chronic Lymphoc...
Small Lymphocyt...
Pirtobrutinib
Bendamustine
Rituximab
18 Years - Eli Lilly and Company
A Study of NX-2127 in Adults With Relapsed/Refractory B-cell MalignanciesNCT04830137
Chronic Lymphoc...
Small Lymphocyt...
Waldenstrom Mac...
Mantle Cell Lym...
Marginal Zone L...
Follicular Lymp...
Diffuse Large B...
Primary Central...
NX-2127
18 Years - Nurix Therapeutics, Inc.
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