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Spots Global Cancer Trial Database for central nervous system lymphoma

Every month we try and update this database with for central nervous system lymphoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Molecular Prognosis of Lymphomas of the Central Nervous System (ALYCE-molecular)NCT03859544
Central Nervous...
Retrospective s...
18 Years - Hospices Civils de Lyon
Chemotherapy and HAART to Treat AIDS-related Primary Brain LymphomaNCT00267865
AIDS-Related-Pr...
Methotrexate
Rituximab
Leucovorin
18 Years - 99 YearsNational Institutes of Health Clinical Center (CC)
A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS LymphomasNCT04548648
Central Nervous...
Acalabrutinib
Isavuconazole
18 Years - 99 YearsUNC Lineberger Comprehensive Cancer Center
Lenalidomide Maintenance Treatment in Patients With Primary Central Nervous System LymphomaNCT05260619
Central Nervous...
lenalidomide
19 Years - Seoul National University Bundang Hospital
Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral MetastasesNCT00103038
Central Nervous...
Malignant Gliom...
Metastatic Mali...
3 Tesla Magneti...
Dynamic Contras...
Dynamic Suscept...
Ferumoxytol
Gadolinium
MRI-Based Angio...
18 Years - OHSU Knight Cancer Institute
Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma or Newly Diagnosed or Relapsed or Refractory Intraocular LymphomaNCT01722305
B-Cell Lymphoma...
Central Nervous...
Intraocular Lym...
Primary Diffuse...
Recurrent Adult...
Retinal Lymphom...
Dexamethasone
Laboratory Biom...
Pharmacological...
Pomalidomide
18 Years - Mayo Clinic
Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS)NCT03964090
Central Nervous...
Secondary Centr...
TEDD-R
TEDDI-R
Ibrutinib
Cytarabine
Isavuconazole
Methotrexate
18 Years - National Institutes of Health Clinical Center (CC)
Molecular Prognosis of Lymphomas of the Central Nervous System (ALYCE-molecular)NCT03859544
Central Nervous...
Retrospective s...
18 Years - Hospices Civils de Lyon
Study on Pembrolizumab for Recurrent Primary Central Nervous System Lymphoma (PCNSL)NCT02779101
Primary Central...
pembrolizumab
18 Years - Medical University of Vienna
Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom MacroglobulinemiaNCT02952508
Waldenstrom Mac...
Multiple Myelom...
Chronic Lymphoc...
Small Lymphocyt...
Lymphoplasmacyt...
Marginal Zone L...
Mantle Cell Lym...
Diffuse Large B...
Central Nervous...
Iopofosine I 13...
Iopofosine I 13...
Iopofosine I 13...
18 Years - Cellectar Biosciences, Inc.
Study of Tissue Samples From Patients With Glioma or Other Brain TumorsNCT00967200
Central Nervous...
laboratory biom...
pharmacogenomic...
18 Years - 120 YearsUniversity Hospital, Montpellier
Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System LymphomaNCT00293475
Central Nervous...
Carboplatin
Mannitol
Methotrexate
Quality-of-Life...
Rituximab
Sodium Thiosulf...
18 Years - 75 YearsOHSU Knight Cancer Institute
Treatment of Recurrent Primary or Secondary Central Nervous System (CNS) Lymphoma With ALIMTA (Pemetrexed)NCT00916630
Central Nervous...
pemetrexed
18 Years - Massachusetts General Hospital
Secondary Central Nervous System Lymphoma Registry - CharitéNCT05114330
Central Nervous...
Non-Hodgkin Lym...
- Charite University, Berlin, Germany
Methotrexate, Mannitol, Rituximab, and Carboplatin in Treating Patients With Newly Diagnosed Primary Central Nervous System LymphomaNCT00293475
Central Nervous...
Carboplatin
Mannitol
Methotrexate
Quality-of-Life...
Rituximab
Sodium Thiosulf...
18 Years - 75 YearsOHSU Knight Cancer Institute
Intermediate Dose of IV MTX as CNS Prophylaxis for High Risk DLBCLNCT05054426
Diffuse Large B...
Central Nervous...
Methotrexate
18 Years - Peking Union Medical College Hospital
Orelabrutinib Combined With Pemetrexed For Relapsed/Refractory Central Nervous System LymphomaNCT05209620
Central Nervous...
ICP-022
Pemetrexed
18 Years - 75 YearsHenan Cancer Hospital
Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom MacroglobulinemiaNCT02952508
Waldenstrom Mac...
Multiple Myelom...
Chronic Lymphoc...
Small Lymphocyt...
Lymphoplasmacyt...
Marginal Zone L...
Mantle Cell Lym...
Diffuse Large B...
Central Nervous...
Iopofosine I 13...
Iopofosine I 13...
Iopofosine I 13...
18 Years - Cellectar Biosciences, Inc.
Long-term Outcome of AIDS-related Primary Central Nervous System Lymphoma Treated With High Dose Methotrexate and Combined Antiretroviral TherapyNCT03690895
Central Nervous...
AIDS Related Ly...
Retrospective s...
18 Years - Fondation Ophtalmologique Adolphe de Rothschild
Long-term Outcome of AIDS-related Primary Central Nervous System Lymphoma Treated With High Dose Methotrexate and Combined Antiretroviral TherapyNCT03690895
Central Nervous...
AIDS Related Ly...
Retrospective s...
18 Years - Fondation Ophtalmologique Adolphe de Rothschild
Rituximab,Zanubrutinib in Combination With Lenalidomide, Followed by Zanubrutinib or Lenalidomide Maintenance in Patients With Primary or Secondary CNS LymphomaNCT04938297
Central Nervous...
Rituximab, Lena...
Lenalidomide, Z...
Lenalidomide
18 Years - Henan Cancer Hospital
Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral MetastasesNCT00103038
Central Nervous...
Malignant Gliom...
Metastatic Mali...
3 Tesla Magneti...
Dynamic Contras...
Dynamic Suscept...
Ferumoxytol
Gadolinium
MRI-Based Angio...
18 Years - OHSU Knight Cancer Institute
Nordic Study in Newly Diagnosed Primary Central Nervous System (CNS) LymphomaNCT01458730
Central Nervous...
Immunochemother...
18 Years - 75 YearsUniversity of Aarhus
Lenalidomide Maintenance Treatment in Patients With Primary Central Nervous System LymphomaNCT05260619
Central Nervous...
lenalidomide
19 Years - Seoul National University Bundang Hospital
Long-term Follow-up Study of Patients Receiving CAR-T CellsNCT03375619
Chronic Lymphoc...
Lymphomas Non-H...
Lymphoma, Small...
Mantle Cell Lym...
Central Nervous...
Diffuse Large B...
Follicular Lymp...
Burkitt Lymphom...
Multiple Myelom...
Long-Term Follo...
18 Years - 80 YearsMedical College of Wisconsin
Acalabrutinib in CNSLNCT04906902
Central Nervous...
Refractory Cent...
Recurrent Centr...
Acalabrutinib
18 Years - Dana-Farber Cancer Institute
Cognitive Functioning and Quality of Life in CNS LymphomaNCT00581737
Lymphoma
Central Nervous...
- Memorial Sloan Kettering Cancer Center
Trial for Patients With Newly Diagnosed Primary Central Nervous System (CNS) LymphomaNCT01011920
Central Nervous...
Methotrexate
Ara-C
Rituximab
Thiotepa
radiotherapy
BCNU
APBSCT
18 Years - 65 YearsInternational Extranodal Lymphoma Study Group (IELSG)
A Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain LymphomaNCT00221325
Central Nervous...
Intraocular Lym...
Intraventricula...
18 Years - University of California, San Francisco
Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic MalignanciesNCT05011045
Central Nervous...
Hematopoietic a...
Leukemia
Lymphoma
Plasma Cell Mye...
Secondary Centr...
Magnetic Resona...
Neurocognitive ...
Quality-of-Life...
Questionnaire A...
18 Years - M.D. Anderson Cancer Center
Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tcm-enriched T-lymphocytes) for the Treatment of Primary Central Nervous System LymphomaNCT05625594
Central Nervous...
Aspiration
Biospecimen Col...
Catheterization
CD19CAR-CD28-CD...
Computed Tomogr...
Cyclophosphamid...
Fludarabine
Leukapheresis
Lumbar Puncture
Magnetic Resona...
Positron Emissi...
18 Years - City of Hope Medical Center
Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Primary Central Nervous System Lymphoma or Newly Diagnosed or Relapsed or Refractory Intraocular LymphomaNCT01722305
B-Cell Lymphoma...
Central Nervous...
Intraocular Lym...
Primary Diffuse...
Recurrent Adult...
Retinal Lymphom...
Dexamethasone
Laboratory Biom...
Pharmacological...
Pomalidomide
18 Years - Mayo Clinic
Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral MetastasesNCT00103038
Central Nervous...
Malignant Gliom...
Metastatic Mali...
3 Tesla Magneti...
Dynamic Contras...
Dynamic Suscept...
Ferumoxytol
Gadolinium
MRI-Based Angio...
18 Years - OHSU Knight Cancer Institute
Selinexor in Combination With MTX+Ritu to Treat R/R CNSLNCT05698147
Central Nervous...
Selinexor
Rituximab
Methotrexate
18 Years - 75 YearsHuashan Hospital
Pharmacogenomics Effects on High-Dose Methotrexate Clearance in Patients With Diffuse Large B-Cell LymphomaNCT06031194
Central Nervous...
Diffuse Large B...
Non-Interventio...
18 Years - Ohio State University Comprehensive Cancer Center
Intermediate Dose of IV MTX as CNS Prophylaxis for High Risk DLBCLNCT05054426
Diffuse Large B...
Central Nervous...
Methotrexate
18 Years - Peking Union Medical College Hospital
Study on Pembrolizumab for Recurrent Primary Central Nervous System Lymphoma (PCNSL)NCT02779101
Primary Central...
pembrolizumab
18 Years - Medical University of Vienna
Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas With Secondary Involvement of the Central Nervous System (CNS)NCT03964090
Central Nervous...
Secondary Centr...
TEDD-R
TEDDI-R
Ibrutinib
Cytarabine
Isavuconazole
Methotrexate
18 Years - National Institutes of Health Clinical Center (CC)
A Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain LymphomaNCT00221325
Central Nervous...
Intraocular Lym...
Intraventricula...
18 Years - University of California, San Francisco
Whole Brain Irradiation in Primary Central Nervous System (CNS) Lymphoma (PCNSL)NCT00153530
Central Nervous...
methotrexate
radiotherapy
18 Years - Charite University, Berlin, Germany
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