Spots Global Cancer Trial Database for central nervous system tumors
Every month we try and update this database with for central nervous system tumors cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects | NCT00187226 | Central Nervous... Brain Tumors | Radiation Thera... Radiation Thera... | 8 Months - 25 Years | St. Jude Children's Research Hospital | |
| Durvalumab in Pediatric and Adolescent Patients | NCT02793466 | Solid Tumor Lymphoma Central Nervous... | Durvalumab; MED... | 1 Year - 17 Years | Children's Hospital Los Angeles | |
| Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors | NCT05081180 | Central Nervous... | Avelumab Lenvatinib | 2 Years - 18 Years | EMD Serono | |
| Combination Chemotherapy in Treating Children With Progressive Brain Tumors | NCT00002944 | Brain Tumors Central Nervous... | carboplatin lomustine procarbazine hy... thioguanine vincristine sul... | - 9 Years | Children's Oncology Group | |
| Bevacizumab in Recurrent Grade II and III Glioma | NCT01164189 | Central Nervous... | Bevacizumab Temozolomide | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Topotecan, G-CSF, and Radiation Therapy in Treating Young Patients With Newly Diagnosed Brain Stem Glioma | NCT00107471 | Brain Tumors Central Nervous... | filgrastim topotecan hydro... radiation thera... | 3 Years - 21 Years | Children's Oncology Group | |
| Rare CNS Tumors Outcomes &Risk | NCT03251989 | High Grade Meni... Ependymoma Medulloblastoma PNET Primary CNS Sar... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors | NCT00003203 | Brain Tumors Central Nervous... Neuroblastoma | filgrastim carboplatin cisplatin cyclophosphamid... vincristine sul... adjuvant therap... radiation thera... | 3 Years - 21 Years | Children's Oncology Group | |
| Cabozantinib for Patients With Recurrent or Progressive Meningioma | NCT05425004 | Meningioma | Cabozantinib | 18 Years - | Baptist Health South Florida | |
| Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma | NCT00031590 | Brain Tumors Central Nervous... Medulloblastoma | Cisplatin Cyclophosphamid... Etoposide Lomustine Vincristine Craniospinal Ra... | 3 Years - 30 Years | Children's Hospital of Philadelphia | |
| Temozolomide, Nedaplatin, Vincristine, and Radiotherapy as First-line Treatment in Newly Diagnosed Primary CNS Lymphoma | NCT01735747 | Central Nervous... | Radiotherapy nedaplatin vincristine Temozolomide | 20 Years - 75 Years | Shandong Cancer Hospital and Institute | |
| Study of ONO-7579 in Patients With Advanced Solid Tumors/ NTRK Gene Fusion Positive Advanced Solid Tumors | NCT03182257 | Solid Tumor | ONO-7579 | 18 Years - | Ono Pharmaceutical Co. Ltd | |
| Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma | NCT00003935 | Brain Tumors Central Nervous... | etoposide vincristine sul... radiation thera... | 3 Years - 21 Years | Children's Oncology Group | |
| Nuclear Imaging of Human CSF Flow Using Ga-67 Citrate and In-111 DTPA | NCT00477503 | Central Nervous... Brain Tumors | Gallium-67 Citr... In-111 DTPA (In... | 2 Years - | M.D. Anderson Cancer Center | |
| Cabozantinib for Patients With Recurrent or Progressive Meningioma | NCT05425004 | Meningioma | Cabozantinib | 18 Years - | Baptist Health South Florida | |
| Bevacizumab in Recurrent Grade II and III Glioma | NCT01164189 | Central Nervous... | Bevacizumab Temozolomide | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors | NCT00876993 | Central Nervous... | Bevacizumab Irinotecan Temozolomide | 18 Months - 23 Years | Johns Hopkins All Children's Hospital | |
| Assessing the Effectiveness of Individual Education Plans for Childhood Cancer Survivors | NCT00945828 | Acute Lymphobla... Central Nervous... Lymphoma | Annual Interven... Quarterly Monit... | 6 Years - 12 Years | University of Miami | |
| Pemetrexed and Temozolomide in Treating Patients With Relapsed Primary Central Nervous System Lymphoma （PCNSL） | NCT01985451 | Central Nervous... | Pemetrexe Temozolomide | 20 Years - 75 Years | Shandong Cancer Hospital and Institute | |
| Carboplatin and Vincristine Plus Radiation Therapy Followed By Adjuvant Chemotherapy in Treating Young Patients With Newly Diagnosed CNS Embryonal Tumors | NCT00003203 | Brain Tumors Central Nervous... Neuroblastoma | filgrastim carboplatin cisplatin cyclophosphamid... vincristine sul... adjuvant therap... radiation thera... | 3 Years - 21 Years | Children's Oncology Group | |
| Study of Lenalidomide With Vorinostat in Pediatric Patients With High Grade or Progressive CNS Tumors | NCT03050450 | Central Nervous... | 25 mg/m2 Lenali... 50 mg/m2 Lenali... 100 mg/m2 Lenal... 150 mg/m2 Lenal... 150 mg/m2 Lenal... | 1 Year - 21 Years | Johns Hopkins All Children's Hospital | |
| Study of BLZ-100 in Pediatric Subjects With CNS Tumors | NCT02462629 | Central Nervous... | BLZ-100 | 1 Month - 30 Years | Blaze Bioscience Inc. | |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma | NCT00003625 | Brain Tumors Central Nervous... | cyclosporine etoposide vincristine sul... radiation thera... | 3 Years - 21 Years | Children's Oncology Group | |
| OXC401-PO1s/WVU 1309 - A Pilot Study of Fosbretabulin With Bevacizumab in Recurrent High-Grade Gliomas | NCT01052363 | Central Nervous... | Bevacizumab, CA... | 18 Years - | West Virginia University | |
| Combination Chemotherapy in Treating Children With Progressive Brain Tumors | NCT00002944 | Brain Tumors Central Nervous... | carboplatin lomustine procarbazine hy... thioguanine vincristine sul... | - 9 Years | Children's Oncology Group | |
| Combination Chemotherapy Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma | NCT00003935 | Brain Tumors Central Nervous... | etoposide vincristine sul... radiation thera... | 3 Years - 21 Years | Children's Oncology Group | |
| Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma | NCT00031590 | Brain Tumors Central Nervous... Medulloblastoma | Cisplatin Cyclophosphamid... Etoposide Lomustine Vincristine Craniospinal Ra... | 3 Years - 30 Years | Children's Hospital of Philadelphia | |
| Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors | NCT05599984 | Advanced Solid ... | ABBV-706 Cisplatin Budigalimab Carboplatin | 18 Years - | AbbVie | |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma | NCT00003625 | Brain Tumors Central Nervous... | cyclosporine etoposide vincristine sul... radiation thera... | 3 Years - 21 Years | Children's Oncology Group | |
| Chemotherapy With CD133+ Select Autologous Hematopoietic Stem Cells for Children With Solid Tumors and Lymphomas | NCT00152126 | Neuroblastoma Central Nervous... Lymphomas Wilms Tumor | Stem Cell Trans... Busulfan, Melph... | - 25 Years | St. Jude Children's Research Hospital | |
| Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Newly Diagnosed Brain Stem Glioma | NCT00003625 | Brain Tumors Central Nervous... | cyclosporine etoposide vincristine sul... radiation thera... | 3 Years - 21 Years | Children's Oncology Group | |
| Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors | NCT00876993 | Central Nervous... | Bevacizumab Irinotecan Temozolomide | 18 Months - 23 Years | Johns Hopkins All Children's Hospital | |
| OH2 Oncolytic Viral Therapy in Central Nervous System Tumors | NCT05235074 | Central Nervous... | OH2 injection | 18 Years - | Binhui Biopharmaceutical Co., Ltd. | |
| Study of Avelumab in Combination With Lenvatinib for Children With Primary CNS Tumors | NCT05081180 | Central Nervous... | Avelumab Lenvatinib | 2 Years - 18 Years | EMD Serono | |
| OXC401-PO1s/WVU 1309 - A Pilot Study of Fosbretabulin With Bevacizumab in Recurrent High-Grade Gliomas | NCT01052363 | Central Nervous... | Bevacizumab, CA... | 18 Years - | West Virginia University | |
| Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma | NCT00002875 | Brain Tumors Central Nervous... | filgrastim cisplatin cyclophosphamid... lomustine mesna vincristine sul... low-LET electro... low-LET photon ... | 3 Years - 22 Years | Children's Oncology Group | |
| Nuclear Imaging of Human CSF Flow Using Ga-67 Citrate and In-111 DTPA | NCT00477503 | Central Nervous... Brain Tumors | Gallium-67 Citr... In-111 DTPA (In... | 2 Years - | M.D. Anderson Cancer Center | |
| Neoadjuvant Chemotherapy With or Without Second-Look Surgery Followed by Radiation Therapy With or Without Peripheral Stem Cell Transplantation in Treating Patients With Intracranial Germ Cell Tumors | NCT00047320 | Brain Tumor Central Nervous... Childhood Germ ... | carboplatin etoposide ifosfamide thiotepa adjuvant therap... conventional su... neoadjuvant the... peripheral bloo... radiation thera... | 3 Years - 24 Years | Children's Oncology Group | |
| Temozolomide and Topotecan in Treating Patients With Primary CNS Lymphoma | NCT00109798 | Central Nervous... Lymphoma | temozolomide topotecan hydro... | 18 Years - 75 Years | The Methodist Hospital Research Institute | |
| Rare CNS Tumors Outcomes &Risk | NCT03251989 | High Grade Meni... Ependymoma Medulloblastoma PNET Primary CNS Sar... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Etoposide Plus Radiation Therapy Followed by Combination Chemotherapy in Treating Children With Newly Diagnosed Advanced Medulloblastoma | NCT00003573 | Brain Tumors Central Nervous... | filgrastim cisplatin cyclophosphamid... etoposide vincristine sul... radiation thera... | 3 Years - 21 Years | Children's Oncology Group | |
| OH2 Oncolytic Viral Therapy in Central Nervous System Tumors | NCT05235074 | Central Nervous... | OH2 injection | 18 Years - | Binhui Biopharmaceutical Co., Ltd. | |
| POWER UP: Participating Online While Exercising to Recover Using Play | NCT05308407 | Exercise Central Nervous... Tumors | Focus Groups Pilot randomize... | 18 Years - | M.D. Anderson Cancer Center | |
| Study of BLZ-100 in Pediatric Subjects With CNS Tumors | NCT02462629 | Central Nervous... | BLZ-100 | 1 Month - 30 Years | Blaze Bioscience Inc. | |
| Study of Lenalidomide With Vorinostat in Pediatric Patients With High Grade or Progressive CNS Tumors | NCT03050450 | Central Nervous... | 25 mg/m2 Lenali... 50 mg/m2 Lenali... 100 mg/m2 Lenal... 150 mg/m2 Lenal... 150 mg/m2 Lenal... | 1 Year - 21 Years | Johns Hopkins All Children's Hospital | |
| Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma | NCT00002875 | Brain Tumors Central Nervous... | filgrastim cisplatin cyclophosphamid... lomustine mesna vincristine sul... low-LET electro... low-LET photon ... | 3 Years - 22 Years | Children's Oncology Group | |
| Bevacizumab in Recurrent Grade II and III Glioma | NCT01164189 | Central Nervous... | Bevacizumab Temozolomide | 18 Years - | European Organisation for Research and Treatment of Cancer - EORTC | |
| Administration of High Dose Thiotepa and Melphalan With Autologous Hematopoietic Stem Cell Transplant in Children and Adolescents With Solid Tumors | NCT00607984 | Central Nervous... Tumors | thiotepa melpha... | 1 Year - 21 Years | Rabin Medical Center | |
| Study of ONO-7579 in Patients With Advanced Solid Tumors/ NTRK Gene Fusion Positive Advanced Solid Tumors | NCT03182257 | Solid Tumor | ONO-7579 | 18 Years - | Ono Pharmaceutical Co. Ltd | |
| DNA Analysis of Tumor Tissue Samples From Patients With Diffuse Brain Stem Glioma | NCT00899834 | Brain Tumors Central Nervous... | - 18 Years | St. Jude Children's Research Hospital |
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