Spots Global Cancer Trial Database for clinimacs
Every month we try and update this database with for clinimacs cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid Tumors | NCT00640796 | Leukemia, Myelo... Leukemia, Lymph... Juvenile Myelom... T-cell Lymphobl... Myelodysplastic... | Haploidentical ... Chemotherapy CliniMACS | - 18 Years | St. Jude Children's Research Hospital | |
| Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia | NCT04881240 | Acute Lymphobla... Acute Lymphobla... Pediatric ALL | CD19-CAR(Mem) T... Cyclophosphamid... Fludarabine Mesna CliniMACS Leukapheresis | - 21 Years | St. Jude Children's Research Hospital | |
| Clofarabine Plus Cytarabine Versus Conventional Induction Therapy And A Study Of NK Cell Transplantation In Newly Diagnosed Acute Myeloid Leukemia | NCT00703820 | Acute Myeloid L... | Cytarabine Daunorubicin Etoposide Clofarabine CliniMACS | - 21 Years | St. Jude Children's Research Hospital | |
| Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies With Alpha Beta TCell and B Cell Depletion Using the CliniMACS Device | NCT02600208 | Hematologic Mal... | CliniMACs | - 23 Years | Medical College of Wisconsin | |
| Autologous Stem Cell Rescue With CD133+ Selected Cells in High-Risk Neuroblastoma | NCT00539500 | Neuroblastoma | Carboplatin Etoposide Melphalan Stem Cell Infus... ClinicMACS | - | M.D. Anderson Cancer Center | |
| Haploidentical Donor Hematopoietic Progenitor Cell and NK Cell Transplantation for Hematologic Malignancy | NCT01807611 | Leukemia Lymphoma | Total Lymphoid ... Fludarabine Cyclophosphamid... Thiotepa Melphalan HPC,A Infusion TC-NK Infusion G-CSF Mesna CliniMACS Mycophenolate m... | - 21 Years | St. Jude Children's Research Hospital | |
| Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma | NCT01700946 | Recurrent B-Cel... Recurrent Child... | dexamethasone vincristine sul... rituximab clofarabine cyclophosphamid... etoposide aldesleukin pegaspargase methotrexate mercaptopurine cytarabine mitoxantrone teniposide vinblastine natural killer ... laboratory biom... therapeutic hyd... allogeneic hema... CliniMACS | - 21 Years | St. Jude Children's Research Hospital | |
| Bulk Versus Fractionated Stem Cell Infusions in Patients With Hematologic Malignancies Undergoing Stem Cell Transplantation | NCT01596257 | Leukemia | allogeneic hema... CliniMACS | - 75 Years | Memorial Sloan Kettering Cancer Center | |
| TCDαβ/CD45RA Haploidentical Transplantation in Children With Leukemia | NCT04033627 | Relapsed Pediat... Acute Graft-Ver... Relapsed Pediat... | In Vitro T cell... | 2 Months - 18 Years | Shanghai Children's Medical Center | |
| A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas | NCT01625351 | Ewing Sarcoma Gastrointestina... Germ Cell Tumor Hepatic Tumor Lymphoma Wilms Tumor Rhabdoid Tumor Clear Cell Carc... Renal Cell Carc... Melanoma Neuroblastoma Rhabdomyosarcom... Non-rhabdomyosa... | alemtuzumab fludarabine sirolimus Busulfan melphalan stem cells CliniMACS | 2 Years - 21 Years | St. Jude Children's Research Hospital | |
| Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies | NCT00566696 | Leukemia, Acute... Leukemia, Myelo... Leukemia, Myelo... Juvenile Myelom... Hemoglobinuria,... Hodgkin Lymphom... Lymphoma, Non-H... Myelodysplastic... | CliniMACS Stem cell trans... Fludarabine Thioplex® L-phenylalanine... Mycophenolate m... Rituxan™ Alemtuzumab Cyclophosphamid... Anti-thymocyte ... G-CSF Muromonab | - 21 Years | St. Jude Children's Research Hospital | |
| Evaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia | NCT03573700 | Acute Lymphobla... Acute Lymphobla... | Cyclophosphamid... Fludarabine Mesna CliniMACS CD19- specific ... | - 21 Years | St. Jude Children's Research Hospital | |
| Peripheral Blood Stem Cell Transplantation for Hematologic Malignancies With Alpha Beta TCell and B Cell Depletion Using the CliniMACS Device | NCT02600208 | Hematologic Mal... | CliniMACs | - 23 Years | Medical College of Wisconsin | |
| Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies | NCT00566696 | Leukemia, Acute... Leukemia, Myelo... Leukemia, Myelo... Juvenile Myelom... Hemoglobinuria,... Hodgkin Lymphom... Lymphoma, Non-H... Myelodysplastic... | CliniMACS Stem cell trans... Fludarabine Thioplex® L-phenylalanine... Mycophenolate m... Rituxan™ Alemtuzumab Cyclophosphamid... Anti-thymocyte ... G-CSF Muromonab | - 21 Years | St. Jude Children's Research Hospital | |
| Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen | NCT02199041 | Hematological M... | Cyclophosphamid... Thiotepa Fludarabine Melphalan Mesna G-CSF Mycophenolate m... Tacrolimus Methylprednisol... Total lymphoid ... Lymphocyte infu... CliniMACS | - 21 Years | St. Jude Children's Research Hospital | |
| Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastoma | NCT01576692 | Neuroblastoma | Humanized anti-... Chemotherapy Cytokines Natural killer ... CliniMACS | - 21 Years | St. Jude Children's Research Hospital | |
| Therapy for Children With Advanced Stage Neuroblastoma | NCT01857934 | Neuroblastoma | cyclophosphamid... topotecan hu14.18K322A peripheral bloo... surgical resect... cisplatin etoposide doxorubicin vincristine busulfan melphalan peripheral bloo... natural killer ... radiation thera... GM-CSF G-CSF mesna levetiracetam interleukin-2 Isotretinoin CliniMACS | - 18 Years | St. Jude Children's Research Hospital | |
| Pilot Study of Expanded, Donor Natural Killer Cell Infusions for Refractory Non-B Lineage Hematologic Malignancies and Solid Tumors | NCT00640796 | Leukemia, Myelo... Leukemia, Lymph... Juvenile Myelom... T-cell Lymphobl... Myelodysplastic... | Haploidentical ... Chemotherapy CliniMACS | - 18 Years | St. Jude Children's Research Hospital | |
| Study of CD19-directed Allogeneic Memory T-cell Therapy for Relapsed/Refractory CD19+ Leukemia | NCT04881240 | Acute Lymphobla... Acute Lymphobla... Pediatric ALL | CD19-CAR(Mem) T... Cyclophosphamid... Fludarabine Mesna CliniMACS Leukapheresis | - 21 Years | St. Jude Children's Research Hospital | |
| Combination Chemotherapy, Monoclonal Antibody, and Natural Killer Cells in Treating Young Patients With Recurrent or Refractory Neuroblastoma | NCT01576692 | Neuroblastoma | Humanized anti-... Chemotherapy Cytokines Natural killer ... CliniMACS | - 21 Years | St. Jude Children's Research Hospital | |
| CD34+ Enriched Transplants From HLA-Compatible Patients With Hematologic Malignancies | NCT04282174 | Hematologic Dis... Hematologic Mal... Acute Lymphobla... Acute Myeloid L... Chronic Myeloge... Chronic Lymphoc... | CliniMACS Bone Marrow Tra... Hyperfractionat... Thiotepa Cyclophosphamid... Busulfan Melphalan Fludarabine | - 74 Years | Baptist Health South Florida | |
| Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior Transplantation | NCT02790515 | Acute Lymphobla... Acute Myeloid L... Myeloid Sarcoma Chronic Myeloid... Juvenile Myelom... Myelodysplastic... Non-Hodgkin Lym... | Anti-thymocyte ... Blinatumomab Cyclophosphamid... Fludarabine G-CSF Melphalan Mesna Rituximab Tacrolimus Thiotepa HPC,A Infusion CliniMACS Sirolimus | - 21 Years | St. Jude Children's Research Hospital | |
| Therapy for Children With Advanced Stage Neuroblastoma | NCT01857934 | Neuroblastoma | cyclophosphamid... topotecan hu14.18K322A peripheral bloo... surgical resect... cisplatin etoposide doxorubicin vincristine busulfan melphalan peripheral bloo... natural killer ... radiation thera... GM-CSF G-CSF mesna levetiracetam interleukin-2 Isotretinoin CliniMACS | - 18 Years | St. Jude Children's Research Hospital | |
| A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas | NCT02130869 | Neuroblastoma Lymphoma High-risk Tumor | CD133+ selected... IL-2 hu14.18K322A Busulfan Melphalan GM-CSF Bendamustine Etoposide Cytarabine Carboplatin Haploidentical ... G-CSF Etoposide phosp... CliniMACS | - 21 Years | St. Jude Children's Research Hospital | |
| Cord Blood With T-Cell Depleted Haplo-identical Peripheral Blood Stem Cell Transplantation for Hematological Malignancies | NCT01682226 | Leukemia Myelodysplastic... Lymphoma | CliniMACS Fract... CliniMACS Fract... Haploidentical ... | 2 Years - 70 Years | Memorial Sloan Kettering Cancer Center |
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