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Spots Global Cancer Trial Database for m7824

Every month we try and update this database with for m7824 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast CancerNCT04489940
Triple Negative...
Bintrafusp alfa
18 Years - EMD Serono
Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical CancerNCT04246489
Uterine Cervica...
Bintrafusp alfa
18 Years - EMD Serono
M7824 (MSB0011359C) in Combination With Gemcitabine in Adults With Previously Treated Advanced Adenocarcinoma of the PancreasNCT03451773
Cancer of Pancr...
Pancreas Cancer
Pancreatic Aden...
Pancreatic Canc...
Pancreatic Neop...
M7824
Gemcitabine
18 Years - National Institutes of Health Clinical Center (CC)
BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)NCT04296942
Breast Cancer
Triple Negative...
HER2+ Breast Ca...
Hormone Recepto...
Metastatic Brea...
Brachyury-TRICO...
Entinostat
M7824
Ado-trastuzumab...
18 Years - National Institutes of Health Clinical Center (CC)
Bioimaging Study of 89Zr-M7824 in NSCLCNCT04297748
Non-Small Cell ...
89Zirconium-M78...
M7824
18 Years - Olivia Newton-John Cancer Research Institute
Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination With TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated With Human Papillomavirus InfectionNCT04247282
Head and Neck C...
Head and Neck N...
M7824
N803
TriAd vaccine
18 Years - National Institutes of Health Clinical Center (CC)
M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)NCT03833661
Biliary Tract C...
Cholangiocarcin...
Gallbladder Can...
M7824
18 Years - EMD Serono
M7824 in Combination With Chemotherapy in Stage IV Non-small Cell Lung Cancer (NSCLC)NCT03840915
Carcinoma, Non-...
Cisplatin
Carboplatin
Pemetrexed
Nab-paclitaxel
Gemcitabine
Docetaxel
M7824
Carboplatin
Carboplatin
Bintrafusp alfa
Paclitaxel
18 Years - EMD Serono
Aerosolized Azacytidine as Epigenetic Priming for Bintrafusp Alfa-Mediated Immune Checkpoint Blockade in Patients With Unresectable Pulmonary Metastases From Sarcomas, Germ Cell Tumors, or Epithelial MalignanciesNCT04648826
Sarcomas
Melanomas
Germ Cell Tumor...
Epithelial Mali...
Pulmonary Metas...
AeroEclipse II ...
Bintrafusp alfa
Azacytidine
18 Years - National Institutes of Health Clinical Center (CC)
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi SarcomaNCT04303117
Kaposi Sarcoma
NHS-IL12
M7824
18 Years - National Institutes of Health Clinical Center (CC)
Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination With BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) With CV301 TRICOM in Advanced Solid Tumors (STAT)NCT04574583
Metastatic Canc...
Solid Tumors
SX-682
M7824
MVA-BN-CV301
recombinant fow...
18 Years - National Institutes of Health Clinical Center (CC)
HPV Vaccine PRGN-2009 Alone or in Combination With Anti-PDL1/TGF-Beta Trap (M7824) in Subjects With HPV Associated CancersNCT04432597
HPV Positive Ca...
Vulvar, Vaginal...
Anal Cancer
Oropharyngeal C...
Cervical Cancer
PRGN-2009 (Phas...
PRGN-2009 (Phas...
M7824
MRI
Bone scan
CT scan
Brain CT
Brain MRI
Biopsy (Phase I...
Biopsy (Phase I...
18 Years - National Institutes of Health Clinical Center (CC)
NHS-IL12 Monotherapy and in Combination With M7824 in Advanced Kaposi SarcomaNCT04303117
Kaposi Sarcoma
NHS-IL12
M7824
18 Years - National Institutes of Health Clinical Center (CC)
M7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)NCT03631706
Non-small Cell ...
M7824
Pembrolizumab
18 Years - EMD Serono
BN-Brachyury, Entinostat, Adotrastuzumab Emtansine and M7824 in Advanced Stage Breast Cancer (BrEAsT)NCT04296942
Breast Cancer
Triple Negative...
HER2+ Breast Ca...
Hormone Recepto...
Metastatic Brea...
Brachyury-TRICO...
Entinostat
M7824
Ado-trastuzumab...
18 Years - National Institutes of Health Clinical Center (CC)
M9241 in Combination With Docetaxel in Adults With Metastatic Castration Sensitive and Castration Resistant Prostate CancerNCT04633252
Cancer Of Prost...
Prostate Neopla...
ADT
Prednisone
M7824
Docetaxel
M9241
18 Years - National Institutes of Health Clinical Center (CC)
M7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)NCT03631706
Non-small Cell ...
M7824
Pembrolizumab
18 Years - EMD Serono
A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial CancerNCT04349280
Neoplasms
Bintrafusp alfa
18 Years - GlaxoSmithKline
Bintrafusp Alfa Combination Therapy in Participants With Cervical Cancer (INTR@PID 046)NCT04551950
Cervical Cancer
M7824
Carboplatin
Paclitaxel
Bevacizumab
Cisplatin
Radiotherapy
18 Years - EMD Serono
Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTCNCT04066491
Biliary Tract C...
Cholangiocarcin...
Gallbladder Can...
M7824
Placebo
Gemcitabine
Cisplatin
18 Years - EMD Serono
Bintrafusp Alfa Monotherapy in Platinum-Experienced Cervical CancerNCT04246489
Uterine Cervica...
Bintrafusp alfa
18 Years - EMD Serono
Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast CancerNCT04489940
Triple Negative...
Bintrafusp alfa
18 Years - EMD Serono
M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer)NCT03833661
Biliary Tract C...
Cholangiocarcin...
Gallbladder Can...
M7824
18 Years - EMD Serono
Bintrafusp Alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary MalignanciesNCT04235777
Urothelial Canc...
Bladder Cancer
Genitourinary C...
Urogenital Neop...
Urogenital Canc...
M7824
M9241
Stereotactic bo...
18 Years - National Institutes of Health Clinical Center (CC)
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