Spots Global Cancer Trial Database for maintenance therapy
Every month we try and update this database with for maintenance therapy cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Rucaparib MAintenance After Bevacizumab Maintenance Following Carboplatin Based First Line Chemotherapy in Ovarian Cancer Patients | NCT04227522 | Ovarian Cancer Fallopian Tube ... Primary Periton... Clear Cell Carc... | Rucaparib Placebos | 18 Years - | North Eastern German Society of Gynaecological Oncology | |
| Tandem High Dose Melphalan Versus Triple Intermediate Dose Melphalan and Stem Cell Transplantation in Induction Phase and Prednisolone/IFN Versus IFN in Maintenance Therapy | NCT00205764 | Multiple Myelom... | Melphalan | 19 Years - 70 Years | Austrian Forum Against Cancer | |
| EMD 521873 Plus Radiotherapy in Non Small Cell Lung Cancer (NSCLC) | NCT00879866 | Lung Cancer Non Small Cell ... | EMD 521873 | 18 Years - | Merck KGaA, Darmstadt, Germany | |
| Orteronel Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents | NCT02053311 | Prostate Cancer | Orteronel Placebo | 18 Years - | Swiss Group for Clinical Cancer Research | |
| Efficacy Study of a Maintenance Therapy With Immunomodulator MGN1703 in Patients With Advanced Colorectal Carcinoma | NCT01208194 | Advanced Colore... | MGN1703 Placebo | 18 Years - | Mologen AG | |
| Maintenance Therapy With Autologous Cytokine-induced Killer Cells for Nonsquamous Non-small Cell Lung Cancer | NCT01481259 | Non-small Cell ... | Autologous cyto... Pemetrexed | 18 Years - 75 Years | People's Hospital of Guangxi | |
| ODM-201 Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents. | NCT02933801 | Prostate Cancer... Prostate Cancer | ODM-201 Placebo | 18 Years - | Swiss Group for Clinical Cancer Research | |
| Treatment With Acalabrutinib Post Blood or Marrow Transplantation in Subjects With Mantle Cell Lymphoma | NCT04402138 | Mantle Cell Lym... | Acalabrutinib | 18 Years - | SCRI Development Innovations, LLC | |
| Maintenance Gemcitabine in the Chinese Advanced Lung Cancer | NCT01336192 | Non Small Cell ... | Gemcitabine Best supportive... | 18 Years - 80 Years | Tongji University | |
| Randomized Study of Decitabine in Maintenance Therapy of Acute Myeloid Leukemia (AML) | NCT00398983 | Acute Myelogeno... | Decitabine | 18 Years - | M.D. Anderson Cancer Center | |
| Clinical Study of Chinese Medicine Plus Targeted Therapy Maintenance in Advanced Pulmonary Adenocarcinoma | NCT02889692 | Cancer | YiQiFang YangYinFang YiQiYangYinFang placebo granule... Erlotinib® Gefitinib® Icotinib® | 18 Years - | Shanghai University of Traditional Chinese Medicine | |
| Clinical Research of S-1 Versus Pemetrexed in the Maintenance Treatment of Advanced NSNSCLC | NCT03700333 | Carcinoma, Non-... | S-1 therapy Pemetrexed ther... | 18 Years - 74 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Rucaparib Maintenance Therapy in Advanced Cervical Cancer | NCT03795272 | Cervical Cancer | Rucaparib Placebo | 18 Years - 100 Years | Nordic Society of Gynaecological Oncology - Clinical Trials Unit | |
| Continued, Long-Term Follow-Up and Lenalidomide Maintenance Therapy for Patients on BMT CTN 0702 Protocol (BMT CTN 07LT) | NCT02322320 | Multiple Myelom... | Lenalidomide | 18 Years - 70 Years | National Heart, Lung, and Blood Institute (NHLBI) | |
| ODM-201 Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents. | NCT02933801 | Prostate Cancer... Prostate Cancer | ODM-201 Placebo | 18 Years - | Swiss Group for Clinical Cancer Research | |
| Durvalumab Combined With Surufatinib as Maintenance Therapy in Patients With Advanced Biliary Tract Cancer | NCT06255262 | Biliary Tract C... | Surufatinib Durvalumab | 18 Years - | China Medical University, China | |
| Panitumumab-based Maintenance in Patients With RAS Wild-type, Metastatic Colorectal Cancer (Valentino) | NCT02476045 | Metastatic Colo... | 5-fluorouracil,... panitumumab Oxaliplatin, 5-... | 18 Years - | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | |
| A Multicenter, Prospective, Phase II Study of Zanubrutinib for Maintenance in Patients With Mantle Cell Lymphoma | NCT06341556 | Mantle Cell Lym... Maintenance The... | Zanubrutinib | 18 Years - | Fudan University | |
| Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients | NCT04698785 | Bone Sarcoma Osteosarcoma | Treatment by re... Treatment by pl... | 12 Years - | Centre Leon Berard | |
| EDOCH Alternating With DHAP for New Diagnosed Younger MCL | NCT02858804 | Mantle Cell Lym... | Etoposide Doxorubicin Dexamethasone Vincristine Cyclophosphamid... Cytarabine Cisplatin Rituximab Thalidomide Prednisone | 18 Years - 65 Years | Institute of Hematology & Blood Diseases Hospital, China | |
| Intermittent and Maintenance of Icotinib in Combination With Pemetrexed/Carboplatin Compared With Icotinib Single Drug in Ⅲb/IV Non Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Mutation | NCT03151161 | Lung, Carcinoma | Icotinib,Pemetr... Icotinib | 18 Years - 75 Years | Sun Yat-sen University | |
| MM CAR-T to Upgrade Response BMTCTN1902 | NCT05032820 | Multiple Myelom... | Lenalidomide an... | 18 Years - 71 Years | Medical College of Wisconsin | |
| Holmium-166 TARE in Liver Limited Unresectable Colorectal Cancer Patients | NCT06332079 | Colorectal Canc... | 166Holmium TARE Cetuximab Panitumumab 5-Fluorouracil Bevacizumab Capecitabine | 18 Years - | Gruppo Oncologico del Nord-Ovest | |
| Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas | NCT04055220 | Bone Sarcoma Osteosarcoma Ewing Sarcoma Chondrosarcoma Undifferentiate... Leiomyosarcoma Angiosarcoma | Treatment by Re... Treatment by Pl... | 12 Years - | Centre Leon Berard | |
| Clinical Research of S-1 Versus Pemetrexed in the Maintenance Treatment of Advanced NSNSCLC | NCT03700333 | Carcinoma, Non-... | S-1 therapy Pemetrexed ther... | 18 Years - 74 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Intermittent and Maintenance of Erlotinib in Combination With Pemetrexed/Carboplatin in Ⅲb/IV Non Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Mutation | NCT02066038 | Lung, Carcinoma | Erlotinib | 18 Years - 75 Years | Sun Yat-sen University | |
| Zanubrutinib in Maintenance Therapy of DLBCL Patients With Initial Remission | NCT05596097 | Diffuse Large B... | Zanubrutinib | 18 Years - | LanZhou University | |
| Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma | NCT00992446 | Adult Diffuse L... B-Cell Non-Hodg... Follicular Lymp... Mantle Cell Lym... Non-Hodgkin Lym... T-Cell Non-Hodg... | Autologous Hema... Bortezomib Carmustine Cytarabine Etoposide Melphalan Rituximab Vorinostat | 18 Years - | Fred Hutchinson Cancer Center | |
| Holmium-166 TARE in Liver Limited Unresectable Colorectal Cancer Patients | NCT06332079 | Colorectal Canc... | 166Holmium TARE Cetuximab Panitumumab 5-Fluorouracil Bevacizumab Capecitabine | 18 Years - | Gruppo Oncologico del Nord-Ovest | |
| Rucaparib MAintenance After Bevacizumab Maintenance Following Carboplatin Based First Line Chemotherapy in Ovarian Cancer Patients | NCT04227522 | Ovarian Cancer Fallopian Tube ... Primary Periton... Clear Cell Carc... | Rucaparib Placebos | 18 Years - | North Eastern German Society of Gynaecological Oncology | |
| Comparison of 25mg Versus 5 mg Lenalidomide as Maintenance Therapy in Patients With Multiple Myeloma | NCT00891384 | Multiple Myelom... | Lenalidomide Lenalidomide | 18 Years - 75 Years | Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH | |
| Fulvestrant as Maintenance Therapy After First-line Chemotherapy in HER2 - Postmenopausal MBC Patients | NCT02383030 | Metastatic Brea... | Fulvestrant | 18 Years - | Consorzio Oncotech | |
| Determine if Either of 2 Doses of Study Drug Given With a Low-dose of Cyclophosphamide After a Complete or Partial Response to a Platinum-based Second-line Therapy in Women With Recurrent Ovarian Carcinoma Results in a Longer Time to Progression When Compared to the First Time to Progression. | NCT00408967 | Ovarian Cancer | Tucotuzumab cel... | 18 Years - | EMD Serono | |
| ODM-201 Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents. | NCT02933801 | Prostate Cancer... Prostate Cancer | ODM-201 Placebo | 18 Years - | Swiss Group for Clinical Cancer Research | |
| MAintenance Therapy With Aromatase Inhibitor in Epithelial Ovarian Cancer (MATAO) | NCT04111978 | Ovarian Neoplas... Fallopian Tube ... Peritoneal Neop... High-grade Sero... Low-grade Serou... Ovarian Endomet... | Letrozole 2.5mg Placebo | 18 Years - | Swiss GO Trial Group | |
| PankoMab-GEX™ Versus Placebo as Maintenance Therapy in Advanced Ovarian Cancer | NCT01899599 | Ovarian Epithel... Fallopian Tube ... Primary Periton... | PankoMab-GEX Placebo | 18 Years - | Glycotope GmbH | |
| A Study of Oral Venetoclax Tablets and Oral Azacitidine Versus Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy | NCT04102020 | Acute Myeloid L... | Venetoclax Azacitidine CC-486 | 18 Years - | AbbVie | |
| Decitabine, Venetoclax and Blinatumomab for Maintenance Following HSCT in Patients With Ph-Negative B-ALL | NCT06393985 | B-cell Acute Ly... | Decitabine, ven... | 18 Years - 65 Years | The First Affiliated Hospital of Soochow University | |
| Postoperation Maintenance Therapy for Resectable Liver Metastases of Colorectal Cancer Guided by ctDNA | NCT05797077 | Colorectal Canc... Liver Metastase... Circulating Tum... Cancer, Therapy... | Colorectal rese... FOLFOX chemothe... Capecitabine | 18 Years - 75 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
| Ph 2 Maintenance Trial: Ixazomib vs Ixazomib-Lenalidomide for MM Patients | NCT03733691 | Newly Diagnosed... | Ixazomib Lenalidomide | 18 Years - 100 Years | Oncotherapeutics | |
| Phase II Study of Maintenance Capecitabine to Treat Resectable Colorectal Cancer | NCT01880658 | Colorectal Neop... | Capecitabine | 18 Years - 80 Years | Sun Yat-sen University | |
| Treatment With Acalabrutinib Post Blood or Marrow Transplantation in Subjects With Mantle Cell Lymphoma | NCT04402138 | Mantle Cell Lym... | Acalabrutinib | 18 Years - | SCRI Development Innovations, LLC | |
| Efficacy of Regorafenib Combined With Best Supportive Care as Maintenance Treatment in High Grade Bone Sarcomas Patients | NCT04698785 | Bone Sarcoma Osteosarcoma | Treatment by re... Treatment by pl... | 12 Years - | Centre Leon Berard | |
| Niraparib Monotherapy as Maintain and Recurrent Treatment of Endometrial Serous Carcinoma | NCT04716686 | Endometrial Car... Serous Carcinom... | Niraparib | 18 Years - | Shandong University | |
| Maintenance Therapy Using Lenalidomide in Myeloma | NCT00430365 | Myeloma | lenalidomide placebo | 18 Years - 65 Years | University Hospital, Toulouse | |
| Maintenance Therapy With 5-FU/FA Plus Panitumumab vs. 5-FU/FA Alone After Prior Induction and Re-induction After Progress for 1st-line Treatment of Metastatic Colorectal Cancer | NCT01991873 | Metastatic Colo... | Maintenance Che... Panitumumab (Wi... mFOLFOX6 (Withi... Panitumumab (Wi... | 18 Years - | AIO-Studien-gGmbH | |
| IFM 99-02 Thalidomide in Myeloma | NCT00222053 | Multiple Myelom... | Thalidomide Biphosphonates | 18 Years - 65 Years | University Hospital, Toulouse | |
| Maintenance Gemcitabine in the Chinese Advanced Lung Cancer | NCT01336192 | Non Small Cell ... | Gemcitabine Best supportive... | 18 Years - 80 Years | Tongji University | |
| Intermittent and Maintenance of Erlotinib in Combination With Pemetrexed/Carboplatin in Ⅲb/IV Non Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Mutation | NCT02066038 | Lung, Carcinoma | Erlotinib | 18 Years - 75 Years | Sun Yat-sen University | |
| Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma | NCT00992446 | Adult Diffuse L... B-Cell Non-Hodg... Follicular Lymp... Mantle Cell Lym... Non-Hodgkin Lym... T-Cell Non-Hodg... | Autologous Hema... Bortezomib Carmustine Cytarabine Etoposide Melphalan Rituximab Vorinostat | 18 Years - | Fred Hutchinson Cancer Center | |
| Bendamustine Combined With Alemtuzumab in Pretreated Chronic Lymphocytic Leukemia (CLL) | NCT00951457 | Leukemia, Lymph... | Bendamustine Alemtuzumab | 18 Years - | Arbeitsgemeinschaft medikamentoese Tumortherapie | |
| Nab-paclitaxel Plus Carboplatin Versus Nab-paclitaxel Plus Capecitabine in the Treatment of Advanced Triple-negative Breast Cancer | NCT04159142 | Triple Negative... Nab-paclitaxel | Nab-paclitaxel ... Nab-paclitaxel ... | 18 Years - 70 Years | Hebei Medical University Fourth Hospital | |
| WT1 Analog Peptide Vaccine in Patients With Multiple Myeloma Following Autologous Stem Cell Transplantation | NCT01827137 | Multiple Myelom... Minimal Residua... High-Risk Cance... | WT1 Analog Pept... Sargramostim (G... lenalidomide | 18 Years - | Sellas Life Sciences Group | |
| EDOCH Alternating With DHAP for New Diagnosed Younger MCL | NCT02858804 | Mantle Cell Lym... | Etoposide Doxorubicin Dexamethasone Vincristine Cyclophosphamid... Cytarabine Cisplatin Rituximab Thalidomide Prednisone | 18 Years - 65 Years | Institute of Hematology & Blood Diseases Hospital, China | |
| Phase II Study of Maintenance Capecitabine to Treat Resectable Colorectal Cancer | NCT01880658 | Colorectal Neop... | Capecitabine | 18 Years - 80 Years | Sun Yat-sen University | |
| Rituximab and Autologous Effector Lymphocytes in Non-Hodgkin Follicular Lymphoma in Response to First Line Chemotherapy | NCT01329354 | Follicular Lymp... Follicular Non-... Autologous Effe... | Autologous effe... | 18 Years - 75 Years | Clinica Universidad de Navarra, Universidad de Navarra | |
| Fruquintinib as a Maintenance Therapy Following First-line Treatment for Metastatic Colorectal Cancer | NCT04296019 | Colo-rectal Can... | Fruquintinib | 18 Years - 75 Years | Shanghai Zhongshan Hospital | |
| Frontline Therapy in de Novo Multiple Myeloma Patients Under 65 | NCT01206205 | Multiple Myelom... | Lenalidomide, B... | 18 Years - 65 Years | University Hospital, Toulouse | |
| Efficacy of NF-kB Inhibition for Reducing Symptoms During Maintenance Therapy in Multiple Myeloma Patients | NCT01269203 | Multiple Myelom... | Curcumin Placebo | 18 Years - | M.D. Anderson Cancer Center | |
| Clinical Study of Chinese Medicine Plus Targeted Therapy Maintenance in Advanced Pulmonary Adenocarcinoma | NCT02889692 | Cancer | YiQiFang YangYinFang YiQiYangYinFang placebo granule... Erlotinib® Gefitinib® Icotinib® | 18 Years - | Shanghai University of Traditional Chinese Medicine | |
| Orteronel Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents | NCT02053311 | Prostate Cancer | Orteronel Placebo | 18 Years - | Swiss Group for Clinical Cancer Research | |
| Lenalidomide Dose Escalation Combined With Rituximab/Fludarabine in Untreated CLL | NCT00738829 | Leukemia, Lymph... | Lenalidomide Fludarabine Rituximab | 18 Years - | Arbeitsgemeinschaft medikamentoese Tumortherapie | |
| Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702) | NCT01109004 | Multiple Myelom... | Lenalidomide lenalidomide, b... Lenalidomide | - 70 Years | National Heart, Lung, and Blood Institute (NHLBI) | |
| Standard Maintenance Therapy (SMT) vs Local Consolidative Radiation Therapy and SMT in OM-NSCLC | NCT05278052 | Oligometastatic... Metastatic Non ... | Local consolida... Standard mainte... | 18 Years - 99 Years | Tata Memorial Hospital | |
| Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission | NCT01757535 | Leukemia, Myelo... | Oral Azacitidin... Placebo | 55 Years - | Celgene | |
| Bortezomib and Vorinostat as Maintenance Therapy After Autologous Stem Cell Transplant in Treating Patients With Non-Hodgkin Lymphoma | NCT00992446 | Adult Diffuse L... B-Cell Non-Hodg... Follicular Lymp... Mantle Cell Lym... Non-Hodgkin Lym... T-Cell Non-Hodg... | Autologous Hema... Bortezomib Carmustine Cytarabine Etoposide Melphalan Rituximab Vorinostat | 18 Years - | Fred Hutchinson Cancer Center | |
| Ofatumumab Maintenance Treatment vs No Further Treatment in Relapsed CLL Responding to Induction Therapy | NCT01039376 | Leukaemia, Lymp... | Ofatumumab Observation | - | Novartis | |
| Efficiency of Imatinib Treatment After 10 Years of Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) (Gist-Ten) | NCT05009927 | Metastatic Gast... C-KIT Mutation Advanced Gastro... | Imatinib tablet... | 18 Years - | Centre Leon Berard | |
| Single Agent Arsenic Trioxide in the Treatment of Newly Diagnosed Acute Promyelocytic Leukemia | NCT00517712 | Acute Promyeloc... | Single agent ar... | - | Christian Medical College, Vellore, India | |
| Physical Activity to Improve Patient Reported Outcomes for Adults With Acute Leukemia | NCT04552912 | Physical Activi... Exercise Acute Leukemia Consolidation Maintenance The... | Build Stamina P... | 18 Years - | Duke University | |
| Rucaparib MAintenance After Bevacizumab Maintenance Following Carboplatin Based First Line Chemotherapy in Ovarian Cancer Patients | NCT04227522 | Ovarian Cancer Fallopian Tube ... Primary Periton... Clear Cell Carc... | Rucaparib Placebos | 18 Years - | North Eastern German Society of Gynaecological Oncology | |
| Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702) | NCT01109004 | Multiple Myelom... | Lenalidomide lenalidomide, b... Lenalidomide | - 70 Years | National Heart, Lung, and Blood Institute (NHLBI) | |
| Maintenance Therapy: Lenalidomide Following Bendamustine and Rituximab Induction Therapy for Chronic Lymphocytic Leukemia | NCT01465230 | Chronic Lymphoc... | Maintenance len... | 18 Years - 90 Years | Yale University | |
| Newton Study (NEW Dosing mainTenance Therapy Ovarian caNcer) | NCT03891576 | Ovarian Cancer Fallopian Tube ... Primary Periton... | Niraparib | 18 Years - | Mario Negri Institute for Pharmacological Research | |
| Single Arm Study of Post-transplant Azacitidine and Chidamide for Prevention of Acute Myelogenous Leukemia Relapse | NCT05270200 | Leukemia, Myelo... | Azacitidine Chidamide | 18 Years - 60 Years | Zhujiang Hospital | |
| First-line R-CVP vs R-CHOP Induction Immunochemotherapy for Indolent Lymphoma and R Maintenance. | NCT00801281 | Follicular Lymp... Marginal Zone L... Small Lymphocyt... Lymphoplasmacyt... | Rituximab Cyclophosphamid... Doxorubicin Vincristine Prednisone 1 Prednisone 2 | 18 Years - | Polish Lymphoma Research Group | |
| Stem Cell Transplant With Lenalidomide Maintenance in Patients With Multiple Myeloma (BMT CTN 0702) | NCT01109004 | Multiple Myelom... | Lenalidomide lenalidomide, b... Lenalidomide | - 70 Years | National Heart, Lung, and Blood Institute (NHLBI) | |
| Orteronel Maintenance Therapy in Patients With Metastatic Castration Resistant Prostate Cancer and Non-progressive Disease After First-line Docetaxel Therapy | NCT01707966 | Prostate Cancer | Orteronel Placebo | 18 Years - | Swiss Group for Clinical Cancer Research | |
| EDOCH Alternating With DHAP for New Diagnosed Younger MCL | NCT02858804 | Mantle Cell Lym... | Etoposide Doxorubicin Dexamethasone Vincristine Cyclophosphamid... Cytarabine Cisplatin Rituximab Thalidomide Prednisone | 18 Years - 65 Years | Institute of Hematology & Blood Diseases Hospital, China | |
| Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas | NCT04055220 | Bone Sarcoma Osteosarcoma Ewing Sarcoma Chondrosarcoma Undifferentiate... Leiomyosarcoma Angiosarcoma | Treatment by Re... Treatment by Pl... | 12 Years - | Centre Leon Berard |
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