Neoplasms

Digestive System Diseases

Diseases and Abnormalities at or Before Birth

All Conditions

Symptoms and General Pathology

Wounds and Injuries

Skin and Connective Tissue Diseases

Rare Diseases

Adenomatous Polyposis Coli

Syndrome

Recurrence

Crohn Disease

Surgical Wound

Polyps

Adenomatous Polyps

Peutz-Jeghers Syndrome

Intestinal Polyposis

Colonic Neoplasms

Inflammatory Bowel Diseases

Intestinal Diseases

Gastroenteritis

Gastrointestinal Diseases

Colorectal Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Colonic Diseases

Adenoma

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Neoplastic Syndromes, Hereditary

Genetic Diseases, Inborn

Lentigo

Melanosis

Hyperpigmentation

Pigmentation Disorders

Skin Diseases

Familial Adenomatous Polyposis

MYH-associated Polyposis

Patients undergo single incision laparoscopic surgery with GelPort® attachment.

Undergo single incision laparoscopic surgery

therapeutic laparoscopic surgery

David Renton, MD

This study is being done to evaluate single incision laparoscopic surgery (SILS) for colorectal diseases, compared to multi-port laparoscopic surgery. This study is also intended to standardize the SILS technique for colorectal diseases

PRIMARY OBJECTIVES:

I. To report the experience of SILS procedure in the treatment of colorectal disease.

II. To standardize the SILS technique.

OUTLINE:

Patients undergo single incision laparoscopic surgery with GelPort® attachment.

After completion of study treatment, patients are followed up at 2 weeks, 3 and 6 months, and at 1 year.

Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease

Single Incision Laparoscopic Surgery (SILS) for Colorectal Disease - A Novel Approach

Summarized using descriptive statistics (i.e. means, standard deviations, 95% confidence intervals for continuous variables, and frequencies for discrete data).

Linear mixed model will be applied with repeated measures considering the observations from the same patient are correlated.

Ohio State University Comprehensive Cancer Center

patients with colorectal cancer and undergo single incision laparoscopic surgery

patients with colorectal cancer and undergo conventional laparoscopic surgery

Patients undergo single incision laparoscopic surgery

single incision laparoscopic surgery

Patients undergo conventional laparoscopic surgery

conventional laparoscopic surgery

Liu Kun, MD

Single incision laparoscopic surgery (SILS) is the further development of the concept of minimally invasive surgery for colorectal cancer,which rapidly developed in the field of colorectal surgery. Through the development of single hole laparoscopic colorectal cancer radical surgery and clinical study and follow up accordingly, evaluating the feasibility, surgical effectiveness and economy help to promote the popularization and application of single hole laparoscopic techniques in the field.

The patients with colorectal cancer will randomly divided into single incision laparoscopic surgery group and conditional laparoscopic surgery group. The operation time, blood loss, the incidence of lymph node , the number of postoperative complications, the gastrointestinal function recovery time, postoperative hospital stay，the number of local recurrence and distant metastasis, survival rate and the total cost of hospitalization will be evaluated to confirm the feasibility of single incision laparoscopic surgery is effective and economical. It is worthy of clinical application.

Single Incision Laparoscopic Colorectal Surgery

Single Incision Laparoscopic Surgery (SILS) for Colorectal Disease

Estimated blood loss（milliliters，ml）

Length of proximal and distal margin （centimeters，cm）

The diameter of tumors（centimeters，cm）

Duration of hospital stay（days after surgery）

Time to first ambulation, flatus, liquid diet and soft diet （hours after surgery）

Postoperative pain is recorded using the visual analog scale (VAS) pain score （0-10 points）tool on postoperative day 1, 2, 3 and the day of discharge

Ruijin Hospital

chief physicion

Rectal Neoplasms

Rectal Diseases

Patients with colorectal cancer undergo conventional laparoscopic surgery（multi-ports）.

Patients with colorectal cancer undergo single-incision laparoscopic surgery.

Patients undergo single-incision laparoscopic surgery. In this group，the surgery is performed through a transumbilical port. The surgeon will adjust surgical position to expose the operative field with the help of gravity. Besides，hand over hand cross and parallel techniques are needed to achieve the SILS. All the other operative procedures are the same as conventional laparoscopic surgery.

Single-incision Laparoscopic Surgery

Patients undergo conventional laparoscopic surgery. In this group，the surgery is performed through 3-5 ports according to the surgeons habits and specific conditions.

Conventional Laparoscopic Surgery

Kun Liu, MD

This study is designed to evaluate the short-term and long-term results after single incision laparoscopic surgery for colorectal cancer（SILSC） compared with conventional laparoscopic surgery for colorectal cancer（CLSC）.

In order to improve cosmetic effect and reduce postoperative pain, single-incision laparoscopic surgery (SILS) is attracting increasing attention. SILS is considered to be the next major advance in the progress of minimally invasive surgical approaches to colorectal disease that is more feasible in generalized use. In most previous studies, SILS for colorectal cancer was feasible and short-term safe compared to conventional laparoscopic surgery (CLS) . However, there is still controversy over its potential better cosmetic effect and less postoperative pain. Moreover, the long-term oncologic outcomes are still inconclusive as only a few studies showed long-term survival data. Up to now, most studies were limited to their retrospective nature and small samples. So more studies, especially large-scale, randomized controlled trials are needed to establish the best indications for SILS for colorectal cancer.

Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer

Multi-center Prospective Randomized Controlled Study of the Single-incision Laparoscopic Surgery Versus Conventional Laparoscopic Surgery for Colorectal Cancer

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Single Incision Laparoscopic Surgery in Treating Patients With Colorectal Disease	NCT01656746	Adenomatous Pol... Crohn Disease Familial Adenom... Hereditary Inte... Recurrent Colon... Stage I Colon C... Stage IIA Colon... Stage IIB Colon... Stage IIC Colon... Stage IIIA Colo... Stage IIIB Colo... Stage IIIC Colo...	therapeutic lap...	18 Years - 80 Years	Ohio State University Comprehensive Cancer Center
Single Incision Laparoscopic Colorectal Surgery	NCT03151733	Laparoscopic Co...	single incision... conventional la...	18 Years - 80 Years	Ruijin Hospital
Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer	NCT03633539	Colorectal Canc... Colonic Neoplas... Rectal Neoplasm... Colon Disease Colon Cancer Rectal Cancer Rectal Diseases	Single-incision... Conventional La...	18 Years - 85 Years	Ruijin Hospital
Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer	NCT03633539	Colorectal Canc... Colonic Neoplas... Rectal Neoplasm... Colon Disease Colon Cancer Rectal Cancer Rectal Diseases	Single-incision... Conventional La...	18 Years - 85 Years	Ruijin Hospital
Single Incision Laparoscopic Colorectal Surgery	NCT03151733	Laparoscopic Co...	single incision... conventional la...	18 Years - 80 Years	Ruijin Hospital

Spots Global Cancer Trial Database for sils

Every month we try and update this database with for sils cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for sils

Every month we try and update this database with for sils cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for sils cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.