Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial) NCT05564403 Recurrent Bilia...
Recurrent Dista...
Recurrent Gallb...
Recurrent Intra...
Stage III Dista...
Stage III Hilar...
Stage III Intra...
Stage IV Distal...
Stage IV Hilar ...
Stage IV Intrah...
Unresectable Bi...
Unresectable Di...
Unresectable Ga...
Unresectable In...
Binimetinib
Biopsy
Biospecimen Col...
Bone Scan
Computed Tomogr...
Echocardiograph...
Fluorouracil
Leucovorin Calc...
Magnetic Resona...
Multigated Acqu...
Oxaliplatin
18 Years - National Cancer Institute (NCI) View Testing the Combination of New Anti-cancer Drug Peposertib With Avelumab and Radiation Therapy for Advanced/Metastatic Solid Tumors and Hepatobiliary Malignancies NCT04068194 Cholangiocarcin...
Gallbladder Car...
Stage III Gallb...
Stage III Hilar...
Stage III Intra...
Stage IV Gallbl...
Stage IV Hilar ...
Stage IV Intrah...
Avelumab
Biopsy
Biospecimen Col...
Computed Tomogr...
Hypofractionate...
Peposertib
18 Years - National Cancer Institute (NCI) View NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma NCT06420349 Advanced Cholan...
Metastatic Chol...
Refractory Chol...
Stage III Hilar...
Stage III Intra...
Stage IV Hilar ...
Stage IV Intrah...
Biospecimen Col...
Computed Tomogr...
Heat Shock Fact...
Magnetic Resona...
Positron Emissi...
Ultrasound-Guid...
18 Years - Mayo Clinic View Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma NCT04708067 Locally Advance...
Metastatic Intr...
Stage III Intra...
Stage IIIA Intr...
Stage IIIB Intr...
Stage IV Intrah...
Bintrafusp Alfa
Biopsy
Hypofractionate...
18 Years - M.D. Anderson Cancer Center View Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver NCT04175912 Metastatic Chol...
Metastatic Hepa...
Stage III Hepat...
Stage III Intra...
Stage IIIA Hepa...
Stage IIIA Intr...
Stage IIIB Hepa...
Stage IIIB Intr...
Stage IV Hepato...
Stage IV Intrah...
Stage IVA Hepat...
Stage IVB Hepat...
Unresectable Ch...
Unresectable He...
Unresectable In...
Carboplatin
Paclitaxel
Pevonedistat
18 Years - National Cancer Institute (NCI) View Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma NCT06058663 Locally Advance...
Oligometastatic...
Stage III Intra...
Stage IV Intrah...
Unresectable In...
Angiography
Biopsy
Biospecimen Col...
Computed Tomogr...
Durvalumab
Magnetic Resona...
Positron Emissi...
Tremelimumab
Yttrium-90 Micr...
18 Years - Mayo Clinic View Sacituzumab Govitecan for the Treatment for Patients With Locally Advanced, Recurrent, or Metastatic Cholangiocarcinoma NCT06178588 Locally Advance...
Metastatic Chol...
Recurrent Chola...
Stage III Hilar...
Stage III Intra...
Stage IV Hilar ...
Stage IV Intrah...
Biopsy
Biospecimen Col...
Computed Tomogr...
Magnetic Resona...
Positron Emissi...
Sacituzumab Gov...
18 Years - University of Kansas Medical Center View Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer NCT03579771 Resectable Chol...
Stage IB Intrah...
Stage II Intrah...
Stage III Intra...
Stage IIIA Intr...
Stage IIIB Intr...
Cisplatin
Gemcitabine
Nab-paclitaxel
19 Years - Emory University View Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma NCT06058663 Locally Advance...
Oligometastatic...
Stage III Intra...
Stage IV Intrah...
Unresectable In...
Angiography
Biopsy
Biospecimen Col...
Computed Tomogr...
Durvalumab
Magnetic Resona...
Positron Emissi...
Tremelimumab
Yttrium-90 Micr...
18 Years - Mayo Clinic View Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers NCT03768414 Stage III Dista...
Stage III Gallb...
Stage III Intra...
Stage IIIA Dist...
Stage IIIA Gall...
Stage IIIA Intr...
Stage IIIB Dist...
Stage IIIB Gall...
Stage IIIB Intr...
Stage IV Distal...
Stage IV Gallbl...
Stage IV Intrah...
Stage IVA Gallb...
Stage IVB Gallb...
Unresectable Ex...
Unresectable Ga...
Unresectable In...
Cisplatin
Gemcitabine Hyd...
Nab-paclitaxel
18 Years - SWOG Cancer Research Network View Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma NCT04708067 Locally Advance...
Metastatic Intr...
Stage III Intra...
Stage IIIA Intr...
Stage IIIB Intr...
Stage IV Intrah...
Bintrafusp Alfa
Biopsy
Hypofractionate...
18 Years - M.D. Anderson Cancer Center View Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial) NCT05564403 Recurrent Bilia...
Recurrent Dista...
Recurrent Gallb...
Recurrent Intra...
Stage III Dista...
Stage III Hilar...
Stage III Intra...
Stage IV Distal...
Stage IV Hilar ...
Stage IV Intrah...
Unresectable Bi...
Unresectable Di...
Unresectable Ga...
Unresectable In...
Binimetinib
Biopsy
Biospecimen Col...
Bone Scan
Computed Tomogr...
Echocardiograph...
Fluorouracil
Leucovorin Calc...
Magnetic Resona...
Multigated Acqu...
Oxaliplatin
18 Years - National Cancer Institute (NCI) View Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers NCT03768414 Stage III Dista...
Stage III Gallb...
Stage III Intra...
Stage IIIA Dist...
Stage IIIA Gall...
Stage IIIA Intr...
Stage IIIB Dist...
Stage IIIB Gall...
Stage IIIB Intr...
Stage IV Distal...
Stage IV Gallbl...
Stage IV Intrah...
Stage IVA Gallb...
Stage IVB Gallb...
Unresectable Ex...
Unresectable Ga...
Unresectable In...
Cisplatin
Gemcitabine Hyd...
Nab-paclitaxel
18 Years - SWOG Cancer Research Network View Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma NCT04708067 Locally Advance...
Metastatic Intr...
Stage III Intra...
Stage IIIA Intr...
Stage IIIB Intr...
Stage IV Intrah...
Bintrafusp Alfa
Biopsy
Hypofractionate...
18 Years - M.D. Anderson Cancer Center View NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma NCT06420349 Advanced Cholan...
Metastatic Chol...
Refractory Chol...
Stage III Hilar...
Stage III Intra...
Stage IV Hilar ...
Stage IV Intrah...
Biospecimen Col...
Computed Tomogr...
Heat Shock Fact...
Magnetic Resona...
Positron Emissi...
Ultrasound-Guid...
18 Years - Mayo Clinic View Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer NCT03942328 Stage III Hepat...
Stage III Intra...
Stage IV Hepato...
Stage IV Intrah...
Unresectable He...
Unresectable In...
Atezolizumab
Bevacizumab
External Beam R...
Pheresis
Pneumococcal 13...
Therapeutic Aut...
18 Years - Mayo Clinic View mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma NCT04251715 Liver and Intra...
Stage III Intra...
Stage IIIA Intr...
Stage IIIB Intr...
Stage IV Intrah...
Unresectable In...
Dexamethasone
Floxuridine
Implanted Medic...
Irinotecan
Leucovorin
Oxaliplatin
Quality-of-Life...
18 Years - OHSU Knight Cancer Institute View