Spots Global Cancer Trial Database for unresectable intrahepatic cholangiocarcinoma

Every month we try and update this database with for unresectable intrahepatic cholangiocarcinoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)	NCT05564403	Recurrent Bilia... Recurrent Dista... Recurrent Gallb... Recurrent Intra... Stage III Dista... Stage III Hilar... Stage III Intra... Stage IV Distal... Stage IV Hilar ... Stage IV Intrah... Unresectable Bi... Unresectable Di... Unresectable Ga... Unresectable In...	Binimetinib Biopsy Biospecimen Col... Bone Scan Computed Tomogr... Echocardiograph... Fluorouracil Leucovorin Calc... Magnetic Resona... Multigated Acqu... Oxaliplatin	18 Years -	National Cancer Institute (NCI)
Testing the Combination of Pevonedistat With Chemotherapy for Bile Duct Cancer of the Liver	NCT04175912	Metastatic Chol... Metastatic Hepa... Stage III Hepat... Stage III Intra... Stage IIIA Hepa... Stage IIIA Intr... Stage IIIB Hepa... Stage IIIB Intr... Stage IV Hepato... Stage IV Intrah... Stage IVA Hepat... Stage IVB Hepat... Unresectable Ch... Unresectable He... Unresectable In...	Carboplatin Paclitaxel Pevonedistat	18 Years -	National Cancer Institute (NCI)
Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma	NCT06058663	Locally Advance... Oligometastatic... Stage III Intra... Stage IV Intrah... Unresectable In...	Angiography Biopsy Biospecimen Col... Computed Tomogr... Durvalumab Magnetic Resona... Positron Emissi... Tremelimumab Yttrium-90 Micr...	18 Years -	Mayo Clinic
Durvalumab and SNDX-6532 Following Chemo or Radio-Embolization for Patients With Intrahepatic Cholangiocarcinoma	NCT04301778	Unresectable In...	Durvalumab SNDX-6352	18 Years -	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma	NCT05913661	Carcinoma Intrahepatic Ch... Digestive Syste... PD-1 Inhibitor First-line Trea...	Pemigatinib PD-1 Inhibitors	18 Years -	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma	NCT06058663	Locally Advance... Oligometastatic... Stage III Intra... Stage IV Intrah... Unresectable In...	Angiography Biopsy Biospecimen Col... Computed Tomogr... Durvalumab Magnetic Resona... Positron Emissi... Tremelimumab Yttrium-90 Micr...	18 Years -	Mayo Clinic
Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers	NCT03768414	Stage III Dista... Stage III Gallb... Stage III Intra... Stage IIIA Dist... Stage IIIA Gall... Stage IIIA Intr... Stage IIIB Dist... Stage IIIB Gall... Stage IIIB Intr... Stage IV Distal... Stage IV Gallbl... Stage IV Intrah... Stage IVA Gallb... Stage IVB Gallb... Unresectable Ex... Unresectable Ga... Unresectable In...	Cisplatin Gemcitabine Hyd... Nab-paclitaxel	18 Years -	SWOG Cancer Research Network
Drug-Eluting Bead, Irinotecan Therapy for Unresectable Intrahepatic Cholangiocarcinoma w/Concomitant Gemcitabine and Cisplatin or Carboplatin	NCT01648023	Unresectable In...	LC or ONCOZENE ... Gem-Cis or Gem-...	18 Years -	University of Louisville
Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)	NCT05564403	Recurrent Bilia... Recurrent Dista... Recurrent Gallb... Recurrent Intra... Stage III Dista... Stage III Hilar... Stage III Intra... Stage IV Distal... Stage IV Hilar ... Stage IV Intrah... Unresectable Bi... Unresectable Di... Unresectable Ga... Unresectable In...	Binimetinib Biopsy Biospecimen Col... Bone Scan Computed Tomogr... Echocardiograph... Fluorouracil Leucovorin Calc... Magnetic Resona... Multigated Acqu... Oxaliplatin	18 Years -	National Cancer Institute (NCI)
Pemigatinib Combined With PD-1 Inhibitor in Unresectable or Metastatic Intrahepatic Cholangiocarcinoma	NCT05913661	Carcinoma Intrahepatic Ch... Digestive Syste... PD-1 Inhibitor First-line Trea...	Pemigatinib PD-1 Inhibitors	18 Years -	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Combined Therapy Using D-TACE, Gemcitabine and Cisplatin, and PD1 Antibody in Advanced and Unresectable Intrahepatic Cholangiocarcinoma	NCT05738057	Unresectable In...	Camrelizumab Gemcitabine Inj... Cisplatin injec... Cisplatin-Eluti... D-TACE	18 Years -	Third Affiliated Hospital, Sun Yat-Sen University
Gemcitabine Hydrochloride and Cisplatin With or Without Nab-Paclitaxel in Treating Patients With Newly Diagnosed Advanced Biliary Tract Cancers	NCT03768414	Stage III Dista... Stage III Gallb... Stage III Intra... Stage IIIA Dist... Stage IIIA Gall... Stage IIIA Intr... Stage IIIB Dist... Stage IIIB Gall... Stage IIIB Intr... Stage IV Distal... Stage IV Gallbl... Stage IV Intrah... Stage IVA Gallb... Stage IVB Gallb... Unresectable Ex... Unresectable Ga... Unresectable In...	Cisplatin Gemcitabine Hyd... Nab-paclitaxel	18 Years -	SWOG Cancer Research Network
Drug-Eluting Bead, Irinotecan Therapy for Unresectable Intrahepatic Cholangiocarcinoma w/Concomitant Gemcitabine and Cisplatin or Carboplatin	NCT01648023	Unresectable In...	LC or ONCOZENE ... Gem-Cis or Gem-...	18 Years -	University of Louisville
Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer	NCT03942328	Stage III Hepat... Stage III Intra... Stage IV Hepato... Stage IV Intrah... Unresectable He... Unresectable In...	Atezolizumab Bevacizumab External Beam R... Pheresis Pneumococcal 13... Therapeutic Aut...	18 Years -	Mayo Clinic
mFOLFIRINOX Followed by Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic mFOLFIRI for Unresectable Liver-dominant Intrahepatic Cholangiocarcinoma	NCT04251715	Liver and Intra... Stage III Intra... Stage IIIA Intr... Stage IIIB Intr... Stage IV Intrah... Unresectable In...	Dexamethasone Floxuridine Implanted Medic... Irinotecan Leucovorin Oxaliplatin Quality-of-Life...	18 Years -	OHSU Knight Cancer Institute

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