Spots Global Cancer Trial Database for Proteases in Patients With Prostate Cancer That Has Spread to the Bone
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Trial Identification
Brief Title: Proteases in Patients With Prostate Cancer That Has Spread to the Bone
Official Title: Proteases in Prostate Cancer Bone Metastasis
Study ID: NCT00899665
Study Description
Brief Summary: RATIONALE: Collecting and storing samples of bone marrow and tissue from patients to test in the laboratory may help the study of cancer. PURPOSE: This laboratory study is comparing proteases (enzymes that break down protein) in patients with prostate cancer that has spread to the bone with patients who do not have cancer that has spread to the bone.
Detailed Description: OBJECTIVES: * Examine the roles of proteases and protease-associated molecules in bone metastases in patients with metastatic prostate cancer. OUTLINE: Patients undergo bone marrow aspiration and core bone biopsies. Tissues are analyzed by immunohistochemistry methods, in situ hybridization assays, gelatin zymography and/or Western blot analysis, and gene profiling analysis in order to visualize and quantitate protease or protease-related levels. PROJECTED ACCRUAL: A total of 50 patients will be accrued for this study.
Eligibility
Minimum Age: 40 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Locations
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, United States
Contact Details
Name: Michael L. Cher, MD
Affiliation: Barbara Ann Karmanos Cancer Institute
Role: STUDY_CHAIR
Take Control of Your Skin and Body Changes Today.
Try out Spots for free, set up only takes 2 mins.
Join others from around the world:
