Spots Global Cancer Trial Database for precancerous condition
Every month we try and update this database with for precancerous condition cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Green Tea Extract in Treating Current or Former Smokers With Bronchial Dysplasia | NCT00611650 | Lung Cancer Precancerous Co... Tobacco Use Dis... | defined green t... placebo | 45 Years - 74 Years | British Columbia Cancer Agency | |
| Oral HPV Infection in Young Men | NCT00897273 | Head and Neck C... Infection Precancerous Co... | comparative gen... gene expression... study of socioe... evaluation of c... study of high r... | 18 Years - 21 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Photodynamic Therapy in Treating Patients With Skin Cancer | NCT00002975 | Non-melanomatou... Precancerous Co... | aminolevulinic ... | - | Roswell Park Cancer Institute | |
| Tethered Capsule Endoscope in Screening Participants for Barrett Esophagus | NCT00903136 | Esophageal Canc... Precancerous Co... | questionnaire a... comparison of s... diagnostic endo... esophagogastrod... tethered capsul... | 18 Years - 80 Years | National Cancer Institute (NCI) | |
| Zoledronate in Treating Patients With Cervical Intraepithelial Neoplasia 2/3 or 3 | NCT00278434 | Cervical Cancer Precancerous Co... | Zoledronate Placebo (Saline... | 18 Years - 120 Years | University of California, San Francisco | |
| Study of Pap Smears From Patients Enrolled on Clinical Trial GOG-171 | NCT00898144 | Cervical Cancer Precancerous Co... | Papanicolaou te... laboratory biom... | - | National Cancer Institute (NCI) | |
| Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple Myeloma | NCT00942422 | Multiple Myelom... Precancerous Co... | defined green t... gene expression... protein analysi... laboratory biom... | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Systemic Mastocytosis | NCT00132015 | Chronic Myelopr... Leukemia Lymphoma Nonneoplastic C... Precancerous Co... | tanespimycin | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Spectroscopy in Diagnosing Dysplasia and Neoplasia in the Cervix in Women Undergoing Colposcopy | NCT00632190 | Cervical Cancer Precancerous Co... | fluorophotometr... colposcopic bio... colposcopy light-scatterin... | 18 Years - | National Cancer Institute (NCI) | |
| Beta Alethine in Treating Patients With Myeloma | NCT00006466 | Multiple Myelom... Precancerous Co... | beta alethine | 18 Years - | National Cancer Institute (NCI) | |
| T4N5 Liposome Lotion Compared With Placebo Lotion for Preventing Actinic Keratoses in Patients With Xeroderma Pigmentosum | NCT00002811 | Precancerous Co... | liposomal T4N5 ... | 2 Years - 60 Years | National Cancer Institute (NCI) | |
| Digital Colposcopy in Finding Cervical Intraepithelial Neoplasia in Patients With An Abnormal Pap Smear | NCT00610662 | Cervical Cancer Precancerous Co... | 18 Years - | British Columbia Cancer Agency | ||
| Omega-3 Fatty Acids in Treating Women With Newly Diagnosed Ductal Carcinoma In Situ and/or Atypical Ductal Hyperplasia | NCT00627276 | Breast Cancer Precancerous Co... | omega-3 fatty a... placebo | 21 Years - 120 Years | OHSU Knight Cancer Institute | |
| Spectroscopy in Diagnosing Dysplasia and Neoplasia in the Cervix in Women Undergoing Colposcopy | NCT00632190 | Cervical Cancer Precancerous Co... | fluorophotometr... colposcopic bio... colposcopy light-scatterin... | 18 Years - | National Cancer Institute (NCI) | |
| Photodynamic Therapy in Treating Patients With Premalignant or Early Stage Head and Neck Tumors | NCT00978081 | Head and Neck C... Precancerous Co... | aminolevulinic ... | 18 Years - 120 Years | Abramson Cancer Center at Penn Medicine | |
| Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer | NCT00675636 | Colorectal Canc... Hereditary Non-... Precancerous Co... | study of socioe... evaluation of c... study of high r... | - 100 Years | Vanderbilt University Medical Center | |
| Celecoxib in Preventing Skin Cancer in Patients With Actinic Keratoses | NCT00027976 | Precancerous Co... | celecoxib Placebo | 18 Years - | University of Alabama at Birmingham | |
| Digital Colposcopy in Finding Cervical Intraepithelial Neoplasia in Patients With An Abnormal Pap Smear | NCT00610662 | Cervical Cancer Precancerous Co... | 18 Years - | British Columbia Cancer Agency | ||
| Sulindac in Preventing Melanoma in Healthy Participants Who Are at Increased Risk of Melanoma | NCT00841204 | Precancerous Co... | sulindac placebo laboratory biom... | 18 Years - 65 Years | National Cancer Institute (NCI) | |
| Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers | NCT00900419 | Esophageal Canc... Head and Neck C... Lung Cancer Precancerous Co... | immunohistochem... laboratory biom... sputum cytology biopsy | 21 Years - 90 Years | University of Colorado, Denver | |
| PS-341 in Treating Patients With Advanced Cancer | NCT00006362 | Leukemia Lymphoma Multiple Myelom... Precancerous Co... Unspecified Adu... | bortezomib | 18 Years - | Mayo Clinic | |
| Diindolylmethane in Treating Patients With Abnormal Cervical Cells | NCT00462813 | Cervical Cancer Precancerous Co... | oral microencap... polymerase chai... cervical Papani... cytology specim... colposcopic bio... | - | National Cancer Institute (NCI) | |
| Induction Chemotherapy Followed By Cetuximab and Radiation in HPV-Associated Resectable Stage III/IV Oropharynx Cancer | NCT01084083 | Head and Neck C... Precancerous Co... | cetuximab intensity-modul... Paclitaxel Cisplatin | 18 Years - | Eastern Cooperative Oncology Group | |
| Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia | NCT00335504 | Colon Cancer Precancerous Co... Rectal Cancer | oligofructose-e... sulindac placebo atorvastatin ca... laboratory biom... | 40 Years - | National Cancer Institute (NCI) | |
| Vaccine Therapy in Preventing Human Papillomavirus Infection in Young HIV-Positive Male Patients Who Have Sex With Males | NCT01209325 | Anal Cancer Nonneoplastic C... Penile Cancer Precancerous Co... | quadrivalent hu... laboratory biom... | 13 Years - 26 Years | AIDS Malignancy Consortium | |
| Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple Myeloma | NCT00942422 | Multiple Myelom... Precancerous Co... | defined green t... gene expression... protein analysi... laboratory biom... | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| Self-Sampling in Women Who Do Not Undergo Routine Cervical Screening | NCT00977392 | Health Status U... Precancerous Co... | compliance moni... cervical Papani... educational int... screening quest... survey administ... colposcopy | 25 Years - | National Cancer Institute (NCI) | |
| Sulindac in Preventing Melanoma in Healthy Participants Who Are at Increased Risk of Melanoma | NCT00841204 | Precancerous Co... | sulindac placebo laboratory biom... | 18 Years - 65 Years | National Cancer Institute (NCI) | |
| Cyclooxygenase-2 Expression in Tissue Samples From Patients With a Normal Cervix, Cervical Intraepithelial Neoplasia, or Early Invasive Cervical Cancer | NCT00900081 | Cervical Cancer Precancerous Co... | immunohistochem... laboratory biom... medical chart r... | 18 Years - 120 Years | Wake Forest University Health Sciences | |
| Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas | NCT00030264 | Neurofibromatos... Precancerous Co... | Methotrexate Vinblastine | - 25 Years | Children's Hospital of Philadelphia | |
| Sulindac in Preventing Melanoma in Healthy Participants Who Are at Increased Risk of Melanoma | NCT00841204 | Precancerous Co... | sulindac placebo laboratory biom... | 18 Years - 65 Years | National Cancer Institute (NCI) | |
| Losartan in Treating Patients With Idiopathic Pulmonary Fibrosis | NCT00879879 | Precancerous Co... | losartan | 21 Years - | University of South Florida | |
| Diindolylmethane in Treating Patients With Abnormal Cervical Cells | NCT00462813 | Cervical Cancer Precancerous Co... | oral microencap... polymerase chai... cervical Papani... cytology specim... colposcopic bio... | - | National Cancer Institute (NCI) | |
| Study of Blood Samples From Older Patients at High Risk of Developing Prostate Cancer and From Healthy Male Participants | NCT00898274 | Precancerous Co... Prostate Cancer | immunoenzyme te... laboratory biom... | 45 Years - 65 Years | Case Comprehensive Cancer Center | |
| Photodynamic Therapy in Treating Patients With Precancerous Esophageal Conditions or Early Stage Esophageal Cancer | NCT00281736 | Esophageal Canc... Precancerous Co... | HPPH | 18 Years - | Roswell Park Cancer Institute | |
| Celecoxib in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia | NCT00101335 | Head and Neck C... Precancerous Co... | celecoxib | 18 Years - | Fox Chase Cancer Center | |
| Human Papillomavirus Vaccine Therapy in Treating Men With HIV-1 Infection | NCT00513526 | Infection Precancerous Co... | Gardasil | 18 Years - | AIDS Malignancy Consortium | |
| Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients | NCT00899626 | Colorectal Canc... Esophageal Canc... Gastric Cancer Pancreatic Canc... Precancerous Co... | protein analysi... proteomic profi... biologic sample... laboratory biom... medical chart r... diagnostic colo... diagnostic endo... diagnostic endo... diagnostic surg... endoscopic surg... screening colon... | 18 Years - | Vanderbilt University Medical Center | |
| Rituximab in Treating Patients With Peripheral Neuropathy Caused by Monoclonal Gammopathy of Undetermined Significance | NCT00588822 | Precancerous Co... | Rituximab | 21 Years - 90 Years | Mayo Clinic | |
| Identifying Biomarkers for Early Detection of Cancer in Patients With Cervical Dysplasia or Carcinoma in Situ of the Cervix | NCT00601601 | Cervical Cancer Precancerous Co... | 19 Years - | British Columbia Cancer Agency | ||
| Optical Coherence Tomography of the Airway for Lung Cancer or Lung Disease | NCT00733252 | Lung Cancer Malignant Mesot... Metastatic Canc... Nonmalignant Ne... Precancerous Co... | bronchoscopic a... diagnostic bron... histopathologic... optical coheren... | - | Case Comprehensive Cancer Center | |
| Eflornithine To Prevent Cervical Cancer in Patients With Cervical Intraepithelial Neoplasia | NCT00006079 | Cervical Cancer Precancerous Co... | Eflornithine Placebo | 18 Years - | M.D. Anderson Cancer Center | |
| Biomarkers in the Nose, Throat, and Lung Tissue of Smokers and Non-Smokers | NCT00897364 | Lung Cancer Precancerous Co... | 45 Years - | University of Colorado, Denver | ||
| Endoscopy Every 2 Years or Only as Needed in Monitoring Patients With Barrett Esophagus | NCT00987857 | Esophageal Canc... Precancerous Co... | 2 yearly endosc... comparison of s... diagnostic endo... endoscopic biop... endoscopic proc... quality-of-life... screening metho... | 18 Years - 120 Years | Gloucestershire Hospitals NHS Foundation Trust | |
| Urine Cadmium Levels in Predicting Pancreatic Cancer Risk in Patients With Chronic Pancreatitis | NCT00489671 | Pancreatic Canc... Precancerous Co... | - 120 Years | Wake Forest University Health Sciences | ||
| Human Papillomavirus Vaccine Therapy in Treating Men With HIV-1 Infection | NCT00513526 | Infection Precancerous Co... | Gardasil | 18 Years - | AIDS Malignancy Consortium | |
| Fenretinide in Treating Patients With Cervical Neoplasia | NCT00003075 | Cervical Cancer Precancerous Co... | Fenretinide Placebo | 18 Years - | M.D. Anderson Cancer Center | |
| Fenretinide in Treating Patients With Cervical Neoplasia | NCT00003075 | Cervical Cancer Precancerous Co... | Fenretinide Placebo | 18 Years - | M.D. Anderson Cancer Center | |
| Imiquimod in Preventing Cervical Cancer in Women With Cervical Neoplasia | NCT00031759 | Cervical Cancer Precancerous Co... | imiquimod Ablative or exc... | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia | NCT01164722 | Anal Cancer Neoplasm of Unc... Nonneoplastic C... Precancerous Co... | clinical observ... infrared photoc... | 27 Years - | AIDS Malignancy Consortium | |
| Factors Affecting Patient Participation in AIDS Malignancy Clinical Trials Consortium Clinical Trials | NCT01946217 | HIV Infection Malignant Neopl... Precancerous Co... | questionnaire a... | 18 Years - | AIDS Malignancy Consortium | |
| Vaccine To Prevent Cervical Intraepithelial Neoplasia or Cervical Cancer in Younger Healthy Participants | NCT00128661 | Cervical Cancer Precancerous Co... | human papilloma... hepatitis A ina... | 18 Years - 25 Years | GlaxoSmithKline | |
| Cetuximab in Treating Patients With Ménétrier Disease at High Risk of Developing Stomach Cancer | NCT00477880 | Gastric Cancer Precancerous Co... | Cetuximab | 18 Years - 80 Years | Vanderbilt University Medical Center | |
| Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging | NCT00445718 | Adrenocortical ... Localized Resec... Precancerous Co... | computed tomogr... 3-Tesla magneti... Abdominal Sonog... | - 6 Months | Children's Oncology Group | |
| The Effects of MBSR in Improving Immune Response to Human Papillomavirus in Patients With Cervical Dysplasia | NCT00653146 | Cervical Cancer Precancerous Co... | Mindfulness-Bas... Healthy Lifesty... | 18 Years - | Fox Chase Cancer Center | |
| Fish Oil and Green Tea Extract in Preventing Prostate Cancer in Patients Who Are at Risk for Developing Prostate Cancer | NCT00253643 | Precancerous Co... Prostate Cancer | green tea catec... fish oil placebo placebo | 21 Years - 120 Years | OHSU Knight Cancer Institute | |
| Cetuximab in Treating Patients With Ménétrier Disease at High Risk of Developing Stomach Cancer | NCT00477880 | Gastric Cancer Precancerous Co... | Cetuximab | 18 Years - 80 Years | Vanderbilt University Medical Center | |
| Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas | NCT00053937 | Neurofibromatos... Precancerous Co... | pirfenidone | 3 Years - 21 Years | National Cancer Institute (NCI) | |
| Cyclooxygenase-2 Expression in Tissue Samples From Patients With a Normal Cervix, Cervical Intraepithelial Neoplasia, or Early Invasive Cervical Cancer | NCT00900081 | Cervical Cancer Precancerous Co... | immunohistochem... laboratory biom... medical chart r... | 18 Years - 120 Years | Wake Forest University Health Sciences | |
| Study to Evaluate Safety and Tolerability of BF-200 ALA (Ameluz®) for Photodynamic Therapy in the Treatment of the Expanded Field of Actinic Keratosis on Face and Scalp | NCT05060237 | Actinic Keratos... Keratosis, Acti... Keratosis | BF-200 ALA and ... | 18 Years - | Biofrontera Bioscience GmbH | |
| Infrared Coagulation in Preventing Anal Cancer in Patients With HIV Who Have Anal Neoplasia | NCT00066430 | Anal Cancer Precancerous Co... | infrared photoc... Infrared Coagul... | 18 Years - | AIDS Malignancy Consortium | |
| SGN-00101 Immunotherapy in Treating Patients With Grade III Cervical Intraepithelial Neoplasia | NCT00075569 | Cervical Cancer Precancerous Co... | HspE7 | 18 Years - 120 Years | Albert Einstein College of Medicine | |
| Papilloma Virus Vaccine Therapy in Treating Young Patients With Recurrent Papilloma of the Larynx | NCT00002454 | Precancerous Co... | autologous tumo... | 1 Year - | National Cancer Institute (NCI) | |
| Biological, Genetic, and Lifestyle Risk Factors for Developing Colorectal Adenomas or Polyps in Participants Undergoing Colonoscopy | NCT00625066 | Colorectal Canc... Precancerous Co... | biologic sample... cytology specim... medical chart r... questionnaire a... survey administ... biopsy evaluation of c... screening colon... | 40 Years - 75 Years | Vanderbilt University Medical Center | |
| Zoledronate in Treating Patients With Cervical Intraepithelial Neoplasia 2/3 or 3 | NCT00278434 | Cervical Cancer Precancerous Co... | Zoledronate Placebo (Saline... | 18 Years - 120 Years | University of California, San Francisco | |
| Aspirin Mouthwash in Treating Patients With Oral Leukoplakia | NCT01238185 | Precancerous Co... | acetylsalicylic... gene expression... protein express... laboratory biom... questionnaire a... biopsy | - | National Cancer Institute (NCI) | |
| Optical Coherence Tomography in Tissue Samples From Women Undergoing Mastectomy for the Treatment or Prevention of Breast Ductal Intraepithelial Neoplasia | NCT00807404 | Precancerous Co... | histopathologic... optical coheren... | 18 Years - | City of Hope Medical Center | |
| Gene Expression Profiling of Cervical Cancer Progression in Biopsies and Tissue Samples | NCT00629577 | Cervical Cancer Precancerous Co... | microarray anal... flow cytometry biopsy colposcopy | 19 Years - | British Columbia Cancer Agency | |
| Beta Alethine in Treating Patients With Myeloma | NCT00006466 | Multiple Myelom... Precancerous Co... | beta alethine | 18 Years - | National Cancer Institute (NCI) | |
| Biomarkers in the Nose, Throat, and Lung Tissue of Smokers and Non-Smokers | NCT00897364 | Lung Cancer Precancerous Co... | 45 Years - | University of Colorado, Denver | ||
| Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple Myeloma | NCT00942422 | Multiple Myelom... Precancerous Co... | defined green t... gene expression... protein analysi... laboratory biom... | 18 Years - | Barbara Ann Karmanos Cancer Institute | |
| Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia | NCT01164722 | Anal Cancer Neoplasm of Unc... Nonneoplastic C... Precancerous Co... | clinical observ... infrared photoc... | 27 Years - | AIDS Malignancy Consortium | |
| Folic Acid Clinical Trial for the Prevention of Cervical Cancer | NCT00703196 | Cervical Cancer Precancerous Co... | folic acid placebo | 19 Years - 120 Years | University of Alabama at Birmingham | |
| Celecoxib in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia | NCT00101335 | Head and Neck C... Precancerous Co... | celecoxib | 18 Years - | Fox Chase Cancer Center | |
| A Study to Evaluate the Efficacy and Safety of Tirbanibulin Ointment in Adult Participants With Actinic Keratosis | NCT06135415 | Keratosis, Acti... | Tirbanibulin Vehicle ointmen... | 18 Years - | Almirall, S.A. | |
| Human Papilloma Virus Infection in HIV-Positive Indian Men Who Have Sex With Men | NCT00919997 | Nonneoplastic C... Precancerous Co... | DNA analysis polymerase chai... fluorescence ac... questionnaire a... study of socioe... study of high r... | 18 Years - | AIDS Malignancy Consortium | |
| Erlotinib in Treating Patients With Barrett Esophagus | NCT00566800 | Esophageal Canc... Precancerous Co... | erlotinib hydro... laboratory biom... biopsy | 18 Years - | National Cancer Institute (NCI) | |
| Risk Factors for Barrett's Esophagus in Patients With BE, Gastroesophageal Reflux, or Gastrointestinal Bleeding | NCT00445653 | Precancerous Co... | 18 Years - 90 Years | Massachusetts General Hospital | ||
| Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer | NCT00675636 | Colorectal Canc... Hereditary Non-... Precancerous Co... | study of socioe... evaluation of c... study of high r... | - 100 Years | Vanderbilt University Medical Center | |
| Rituximab in Treating Patients With Peripheral Neuropathy Caused by Monoclonal Gammopathy of Undetermined Significance | NCT00588822 | Precancerous Co... | Rituximab | 21 Years - 90 Years | Mayo Clinic |
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