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Brief Title: Prevention of Colorectal Cancer Through Multiomics Blood Testing
Official Title: Prevention of Colorectal Cancer Through Multiomics Blood Testing
Study ID: NCT04369053
Brief Summary: The PREEMPT CRC study is a prospective multi-center observational study to validate a blood-based test for the early detection of colorectal cancer by collecting blood samples from average-risk participants who will undergo a routine screening colonoscopy.
Detailed Description: Freenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early. The purpose of this prospective multi-center observational study is to validate a blood-based test for the detection of colorectal cancer by collecting blood samples from average-risk participants who will undergo a routine screening colonoscopy.
Minimum Age: 45 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Pinnacle Research Group LLC, Anniston, Alabama, United States
Birmingham VA Medical Center - Alabama, Birmingham, Alabama, United States
University of Alabama at Birmingham, Birmingham, Alabama, United States
Birmingham Gastroenterology Associates, Homewood, Alabama, United States
Advanced Gastroenterology PC, Chandler, Arizona, United States
Southeast Valley Gastro (SEVG), Chandler, Arizona, United States
Associated Gastroenterology Medical Group, Anaheim, California, United States
Matrix Clinical Research, Beverly Hills, California, United States
Precision Research Institute, LLC, Chula Vista, California, United States
Citrus Valley Gastroenterology, Covina, California, United States
Kaiser Permanente Southern California, Downey, California, United States
Paragon Rx Clinical - Garden Grove, Garden Grove, California, United States
Gastro Care Institute, Lancaster, California, United States
Science 37, Los Angeles, California, United States
UCLA Medical Center, Los Angeles, California, United States
St. Joseph Heritage Healthcare, Mission Viejo, California, United States
Inland Empire GI, Murrieta, California, United States
Los Angeles Gastroenterology Institute, Northridge, California, United States
East Bay Center for Digestive Health, Oakland, California, United States
Knowledge Research Center, Orange, California, United States
Sutter Institute for Medical Research, Sacramento, California, United States
University of California San Diego Medical Center, San Diego, California, United States
Precision Research Institute, LLC, San Diego, California, United States
UCSF Mount Zion Medical Center, San Francisco, California, United States
Paragon Rx Clinical - Santa Ana, Santa Ana, California, United States
Digestive Health Associates, Santa Monica, California, United States
Kaiser Permanente Northern California, Walnut Creek, California, United States
Clinical Research of California LLC, Walnut Creek, California, United States
The Center for Gastrointestinal Medicine of Fairfield and Westchester, P.C, Greenwich, Connecticut, United States
Naugatuck Valley GI Consultants, Prospect, Connecticut, United States
Delaware Center for Digestive Care, Newark, Delaware, United States
Veterans Affairs Medical Center, Washington, District of Columbia, United States
Bay Pines VA Healthcare System, Bay Pines, Florida, United States
Hillel Cohen, MD, Boca Raton, Florida, United States
Universal Axon Clinical Research, Doral, Florida, United States
Palmetto Research, LLC, Hialeah, Florida, United States
The Center for Gastrointestinal Disorders, Hollywood, Florida, United States
ENCORE, Jacksonville, Florida, United States
IHS Health, Kissimmee, Florida, United States
Central Florida Gastro Research, Kissimmee, Florida, United States
Pharmax Research Clinic, Miami, Florida, United States
Ocala GI Research, Ocala, Florida, United States
St. Johns Center for Clinical Research, Saint Augustine, Florida, United States
Florida Medical Clinic, LLC, Zephyrhills, Florida, United States
Morehouse, Atlanta, Georgia, United States
Metro Atlanta Gastroenterology, LLC, Atlanta, Georgia, United States
Augusta University, Augusta, Georgia, United States
IACT Health, Columbus, Georgia, United States
Emory University School of Medicine, Conyers, Georgia, United States
Gastroenterology Consultants of Augusta, Evans, Georgia, United States
Gastrointestinal Specialists of Georgia, Marietta, Georgia, United States
Pramukh Clinical Research, Roswell, Georgia, United States
Gastroenterology Consultants of Savannah, PC, Savannah, Georgia, United States
Southeast Georgia Gastroenterology, P.C., Waycross, Georgia, United States
University of Chicago, Chicago, Illinois, United States
Digestive Health Services, a Division of GI Partners of Illinios, Downers Grove, Illinois, United States
NorthShore University Health System, Evanston, Illinois, United States
Edward Hines, Jr. VA Hospital, Hines, Illinois, United States
Suburban Gastroenterology, Naperville, Illinois, United States
Digestive Diseases Consultants of Kankakee, New Lenox, Illinois, United States
GI Partners of Illinois - Southwest Gastroenerology, Oak Lawn, Illinois, United States
Quincy Medical Group, Quincy, Illinois, United States
Springfield Clinic, LLP, Springfield, Illinois, United States
American Health Network of Indiana, LLC, Muncie, Indiana, United States
Digestive Research Alliance of Michiana, South Bend, Indiana, United States
University of Kansas Medical Center Research Institute, Inc., Kansas City, Kansas, United States
Cotton-O'Neil Clinical Research Center, Digestive Health, Topeka, Kansas, United States
Kansas Gastroenterology, LLC, Wichita, Kansas, United States
Tri-State Gastroenterology Associates, PSC, Crestview Hills, Kentucky, United States
Delta Research Partners - Bastrop, Bastrop, Louisiana, United States
Northlake Gastroenterology Associates, Hammond, Louisiana, United States
Delta Research Parnters - Monroe, Monroe, Louisiana, United States
Ochsner Clinic Foundation, New Orleans, Louisiana, United States
Louisiana Research Center, LLC, Shreveport, Louisiana, United States
Woodholme Gastroenterology Associates, Baltimore, Maryland, United States
Chevy Chase Clinical Research, Chevy Chase, Maryland, United States
Gastro Center of Maryland, Columbia, Maryland, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Greater Boston Gastroenterology, Framingham, Massachusetts, United States
South Suburban Gastroenterology, South Weymouth, Massachusetts, United States
University of Minnesota, Minneapolis, Minnesota, United States
Gastroenterology Associates of Mississippi, Columbus, Mississippi, United States
Gastrointestinal Associates, Flowood, Mississippi, United States
Gastrointestinal Associates, Columbia, Missouri, United States
Kansas City VA Medical Center, Kansas City, Missouri, United States
Mercy Washington, Washington, Missouri, United States
LV Gastroenterology Associates, Las Vegas, Nevada, United States
VA Southern Nevada, North Las Vegas, Nevada, United States
VA Sierra Nevada, Reno, Nevada, United States
Advanced Research Institute, Reno, Nevada, United States
Gastroenterology Associates in NJ, Dover, New Jersey, United States
AIG Digestive Disease Research, Florham Park, New Jersey, United States
Digestive Healthcare Center, Hillsborough, New Jersey, United States
Gastroenterology Medical Associates, North Bergen, New Jersey, United States
Dr. Howard N. Guss and Dr. Gagan Beri, Ocean City, New Jersey, United States
Princeton GI Associates, Princeton, New Jersey, United States
Teaneck Gastroenterology Associates, Teaneck, New Jersey, United States
Ocean Family Gastroenterology, Toms River, New Jersey, United States
Advanced Gasteroenterology Group, Union, New Jersey, United States
Center for Digestive Diseases, Union, New Jersey, United States
Samuel S. Stratton VA Medical Center, Albany, New York, United States
Sam Moskowitz, MD, Brooklyn, New York, United States
Associated Gastroenterologists of Central NY, Camillus, New York, United States
North Shore Gastroenterology Associates, Great Neck, New York, United States
South Island Gastro, Lawrence, New York, United States
Mark Coronel, MD, Manorville, New York, United States
Gastrointestinal Associates of Rockland, New City, New York, United States
Mid Hudson Medical Research, PLLC, New Windsor, New York, United States
NYU Grossman School of Medicine, New York, New York, United States
Icahn School of Medicine at Mount Sinai, New York, New York, United States
Cornell, New York, New York, United States
Syracuse Gastroenterological Associates, PC, Syracuse, New York, United States
GastroCare LI, Valley Stream, New York, United States
Long Island Gastrointestinal Specialist, Wantagh, New York, United States
William S. Silver MD & Eric L. Tatar MD PC., West Nyack, New York, United States
Cary Gastro Associates, Cary, North Carolina, United States
University of North Carolina, Chapel Hill, North Carolina, United States
Duke Clinic, Durham, North Carolina, United States
Carolina's GI Research, LLC, Raleigh, North Carolina, United States
PMG Research of Winston-Salem, LLC, Winston-Salem, North Carolina, United States
Trinity Health Center Medical Arts, Minot, North Dakota, United States
Cincinnati GI, Cincinnati, Ohio, United States
Cleveland Clinic Foundation - Central, Cleveland, Ohio, United States
The Ohio State University Wexner Medical Center, Columbus, Ohio, United States
Great Lakes Gastroenterology Research, LLC, Mentor, Ohio, United States
DSI Research, Springboro, Ohio, United States
Summit Medical Group Oregon - BMC, Bend, Oregon, United States
Oregon Health & Science University, Portland, Oregon, United States
The Oregon Clinic, P.C., Portland, Oregon, United States
Eastern Pennsylvania GI & Liver Specialist, Allentown, Pennsylvania, United States
Blair Gastroenterology Associates, Altoona, Pennsylvania, United States
Valley Gastroenterology Associates, Beaver Falls, Pennsylvania, United States
Susquehanna Research Group, LLC, Camp Hill, Pennsylvania, United States
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
UPMC Digestive Diseases Center GAS, Pittsburgh, Pennsylvania, United States
Southeast Medical Research II, LLC, Charleston, South Carolina, United States
Gastroenterology Associates, PA, Greenville, South Carolina, United States
Digestive Disease Research Center, Greenwood, South Carolina, United States
Consultants in GI, West Columbia, South Carolina, United States
ARCare Center of Clinical Research, Franklin, Tennessee, United States
Gastrointestinal Associates of NorthEast Tenn, Johnson City, Tennessee, United States
Tri-Cities Gastroenterology, Kingsport, Tennessee, United States
Gastroenterology Associates, PC, Knoxville, Tennessee, United States
Meharry Medical College, Nashville, Tennessee, United States
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Advanced Gastroenterology, Union City, Tennessee, United States
Texas Oncology, Amarillo, Texas, United States
Gastroenterology Practice Associates, Arlington, Texas, United States
Mohan, Uma Yanamadala, Cypress, Texas, United States
University of Texas Southwestern Medical Center, Dallas, Texas, United States
Ertan Digestive Disease Center, Houston, Texas, United States
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Gastroenterology Consults, Houston, Texas, United States
Hope Digestive and Liver Disease Clinic of Houston, Houston, Texas, United States
Panamericana Family Medicine Clinic, Houston, Texas, United States
Rio Grande Gastroenterology, McAllen, Texas, United States
Gastroenterology Consultants, Pasadena, Texas, United States
Digestive System Healthcare, Pasadena, Texas, United States
Gastroenterology Partners of North Houston, Shenandoah, Texas, United States
Texas Gastro Consultants, Tomball, Texas, United States
Texas Oncology, Tyler, Texas, United States
University of Texas Health Science Center at Tyler, Tyler, Texas, United States
Digestive Health Research of North Texas, Wichita Falls, Texas, United States
Advanced Research Institute, Ogden, Utah, United States
Intermountain, Salt Lake City, Utah, United States
Digestive and Liver Disease Specialists, Ltd., Norfolk, Virginia, United States
Gastroenterology Consultants of SW Virginia, Roanoke, Virginia, United States
UW Medical Center, Seattle, Washington, United States
Washington Gastroenterology - Tacoma Clinic, Tacoma, Washington, United States
GastroIntestinal Associates, S.C., Wausau, Wisconsin, United States
Gastroenterology Associates of Wyoming, Casper, Wyoming, United States
Cleveland Clinic Abu Dhabi, Abu Dhabi, , United Arab Emirates
Name: Aasma Shaukat, MD MPH
Affiliation: University of Minnesota
Role: PRINCIPAL_INVESTIGATOR
Name: Theodore R Levin, MD
Affiliation: The Permanente Medical Group
Role: PRINCIPAL_INVESTIGATOR
Name: Lance Baldo, MD
Affiliation: Freenome Holdings Inc.
Role: STUDY_CHAIR