Spots Global Cancer Trial Database for A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy
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Trial Identification
Brief Title: A Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy
Official Title: A Randomized, Multicenter, Adaptive Phase 3 Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab Versus Bevacizumab Alone in Patients With Recurrent or Progressive Glioblastoma Following Initial Therapy (WIZARD 201G)
Study ID: NCT03149003
Conditions
Study Description
Brief Summary: This is an event driven, adaptive design, a randomized, active-controlled, multicenter, open-label, parallel groups, Phase 3 study of DSP-7888 Dosing Emulsion plus Bevacizumab versus Bevacizumab alone in patients with recurrent or progressive glioblastoma multiforme (GBM) following treatment with first line therapy consisting of surgery and radiation with or without chemotherapy.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Alabama at Birmingham, Birmingham, Alabama, United States
Center for Neurosciences, Tucson, Arizona, United States
Highlands Oncology Group, Fayetteville, Arkansas, United States
UCSD- Moores Cancer Center, La Jolla, California, United States
Kaiser Permanente Los Angeles Medical Center, Los Angeles, California, United States
Cedars Sinai Medical Center, Los Angeles, California, United States
Neuro-Oncology/ US Irvine Medical Center, Orange, California, United States
Sansum Clinic, Santa Barbara, California, United States
John Wayne Cancer Institute, Santa Monica, California, United States
Rocky Mountain Cancer Center, Denver, Colorado, United States
Piedmont brain tumor center, Atlanta, Georgia, United States
Rush University Medical Center, Chicago, Illinois, United States
University of Kentucky / Department of Internal Medicine / Markey Cancer Center, Lexington, Kentucky, United States
Norton Cancer Institute, Louisville, Kentucky, United States
Tufts Medical Center, Boston, Massachusetts, United States
Henry Ford Health System, Detroit, Michigan, United States
Abbott Northwestern Hospital, Minneapolis, Minnesota, United States
Hackensack University Medical Center, Hackensack, New Jersey, United States
Dent Neurosciences Research Center, Amherst, New York, United States
Weill Cornell Medicine, New York, New York, United States
Columbia University Medical Center/ Neurological Institute of NY, New York, New York, United States
University of Rochester Medical Center, Rochester, New York, United States
University Hospitals of Cleveland, Cleveland, Ohio, United States
Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio, United States
University of Toledo, Toledo, Ohio, United States
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
University of Pittsburgh Medical Center (UPMC), Pittsburgh, Pennsylvania, United States
Rhode Island Hospital, Providence, Rhode Island, United States
University of Tennessee Academic Medical Center Cancer Institute, Knoxville, Tennessee, United States
Texas Oncology Austin Midtown, Austin, Texas, United States
Baylor Scott and White, Dallas, Texas, United States
Houston Methodist, Houston, Texas, United States
Mischer Neuroscience Associates/Memorial Hermann Hospital, Houston, Texas, United States
Renovatio Clinical, The Woodlands, Texas, United States
Virginia Cancer Specialists, PC, Fairfax, Virginia, United States
Swedish Medical Center, Seattle, Washington, United States
University of Wisconsin Hospital, Madison, Wisconsin, United States
CancerCare Manitoba, Winnipeg, Manitoba, Canada
Montreal Neurological Institute and Hospital, Montreal, Quebec, Canada
University of Sherbrooke, Sherbrooke, Quebec, Canada
Hokkaido University Hospital, Sapporo, Hokkaido, Japan
Kagoshima University Hospital, Kagoshima-shi, Kagoshima, Japan
Niigata University Medical and Dental Hospital, Chuo Ku, Niigata, Japan
Osaka International Cancer Institute, Chuo Ku, Osaka, Japan
The University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan
National Cancer Center Hospital, Chuo-ku, Tokyo, Japan
Hiroshima University Hospital, Hiroshima, , Japan
Kumamoto University Hospital, Kumamoto, , Japan
University Hospital, Kyoto Prefectural University of Medicine, Kyoto, , Japan
National Hospital Organization Kyoto Medical Center, Kyoto, , Japan
Tokyo Women's Medical University Hospital, Shinjuku-Ku, , Japan
Yamagata University Hospital, Yamagata, , Japan
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Seoul, , Korea, Republic of
Gangnam Severance Hospital, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, , Korea, Republic of
China Medical University Hospital, Taichung, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Chang Gung Memorial Hospital, Taoyuan City, , Taiwan
Contact Details
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