Spots Global Cancer Trial Database for brain cancer
Every month we try and update this database with for brain cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Study of Health Effects of Cosmetic Breast Augmentation | NCT00342953 | Brain Cancer Breast Cancer Lung Cancer Suicide | 21 Years - 69 Years | National Institutes of Health Clinical Center (CC) | ||
| Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas | NCT04869449 | Glioblastoma Glioblastoma Mu... Glioblastoma Mu... Glioblastoma Mu... | Ketoconazole | 18 Years - | Milton S. Hershey Medical Center | |
| Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study | NCT04962672 | Anesthesia Brain Cancer Survival | Propofol group Sevoflurane gro... | 18 Years - | University Health Network, Toronto | |
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer | NCT05106296 | Ependymoma Medulloblastoma Glioblastoma Primary Brain T... | Ibrutinib Indoximod Cyclophosphamid... Etoposide | 12 Years - 25 Years | Augusta University | |
| Genetically-informed Therapies for Patients With Metastatic Cancer | NCT02000739 | Metastatic Canc... | Genetically Inf... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
| Biomarker Analysis of Central Nervous System Tumors | NCT02692898 | Central Nervous... Primary Brain N... Neoplasms, Brai... Cancer of the B... Brain Cancer | - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma | NCT05954858 | Glioma, Maligna... Glioblastoma Glioblastoma Mu... Glioblastoma Mu... High Grade Glio... GBM Brain Cancer | Tissue autograf... | 18 Years - | Northwell Health | |
| Genetically-informed Therapies for Patients With Metastatic Cancer | NCT02000739 | Metastatic Canc... | Genetically Inf... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
| Efficacy of Nivolumab for Recurrent IDH Mutated High-Grade Gliomas | NCT03925246 | High Grade Glio... Brain Cancer | Nivolumab | 18 Years - 85 Years | Assistance Publique - Hôpitaux de Paris | |
| Assessment of Primary and Metastatic Brain Tumor Hypoxia With Fluoromisonidazole, FDG and Water | NCT01246869 | Brain Cancer | [18F]fluoro-2-d... 1H-1-(3-[18F]-f... [15O]water Magnetic Resona... | 18 Years - | University of Utah | |
| Phase I Trial of Arsenic Trioxide and Stereotactic Radiotherapy for Recurrent Malignant Glioma | NCT00185861 | Brain Cancer | Arsenic Trioxid... Stereotactic ra... | 18 Years - | Stanford University | |
| Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling | NCT05943262 | Brain Tumor Brain Cancer | mesoscale nonli... | 20 Years - | National Taiwan University Hospital | |
| A Pilot Study to Determine Nutrition Status in Glioblastoma Multiforme Patients | NCT01770626 | Brain Cancer | Nutrition | 19 Years - | University of Alabama at Birmingham | |
| Tumor Related Epilepsy | NCT02639325 | Epilepsy Cancer Brain Neoplasm | 8 Years - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Spectroscopic MRI, Proton Therapy, and Avastin for Recurrent Glioblastoma | NCT05284643 | Recurrent Gliob... | Intensity Modul... Bevacizumab | 18 Years - | University of Miami | |
| A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects | NCT00187226 | Central Nervous... Brain Tumors | Radiation Thera... Radiation Thera... | 8 Months - 25 Years | St. Jude Children's Research Hospital | |
| Research of Biomarkers of Response to Proton Beam Therapy in Pediatric and Adult Patients. | NCT04367779 | Brain Cancer Meningioma Sarcoma | - | Centre Leon Berard | ||
| Personalized Cellular Vaccine for Brain Metastases (PERCELLVAC3) | NCT02808416 | Brain Cancer Neoplasm Metast... | Personalized ce... | 18 Years - 65 Years | Guangdong 999 Brain Hospital | |
| Histopathologic Evaluation of High Grade Brain Tumors by High Order Diffusion Tensor Imaging | NCT01699269 | High Grade Brai... | peritumoral gli... | 18 Years - 85 Years | University Hospital, Clermont-Ferrand | |
| Convection Enhanced Localized Administration of PRX321 With Real-time Imaging for Therapy of Recurrent Glioblastoma (CLARITY-1) | NCT00797940 | Glioblastoma Mu... | IL-4PE | 18 Years - | Protox Inc. | |
| Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R | NCT02045368 | Breast Cancer Brain Cancer Gastrointestina... Genitourinary C... Gynecologic Can... Head and Neck C... Melanoma Thoracic Cancer... | IGF-Methotrexat... | 18 Years - | IGF Oncology, LLC | |
| Temodar (Temozolomide), Bevacizumab, Lithium and Radiation for High Grade Glioma | NCT01105702 | Brain Cancer | Temozolomide Bevacizumab Lithium Carbona... Radiation | 18 Years - | NYU Langone Health | |
| Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma | NCT02858895 | Glioblastoma Grade IV Astroc... Glioblastoma Mu... Grade IV Glioma | MDNA55 | 18 Years - | Medicenna Therapeutics, Inc. | |
| ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors | NCT01473485 | Glioma Metastatic Brai... | ExAblate Transc... | 18 Years - 75 Years | InSightec | |
| Efficacy Study of TLN-4601 in Patients With Recurring Glioblastoma Multiforme | NCT00730262 | Glioblastoma Mu... | TLN-4601 | 18 Years - | Thallion Pharmaceuticals | |
| Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma | NCT01392209 | Brain Cancer MALIGNANT GLIOM... Glioblastoma Anaplastic Astr... Anaplastic Olig... Anaplastic Olig... Anaplastic Mixe... Malignant Gliom... | Bevacizumab & S... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Study | NCT03951142 | Glioblastoma Brain Metastase... | Losartan | 18 Years - | Oslo University Hospital | |
| Standard Dose Bevacizumab Versus Low Dose Bevacizumab Plus Lomustine (CCNU) for Recurrent Glioblastoma Multiforme (GBM) | NCT01067469 | Brain Cancer Glioblastoma | Standard Dose B... Low Dose Bevaci... Lomustine | 18 Years - | M.D. Anderson Cancer Center | |
| Wearable Devices and Biomarkers Project (Healthiomics) | NCT05106725 | Brain Cancer Neurological Di... Neurological Ca... | 18 Years - | CureScience | ||
| Dendritic Cell Cancer Vaccine for High-grade Glioma | NCT01213407 | Glioblastoma Mu... | Trivax, Temozol... Temozolomide, S... | 3 Years - 70 Years | Activartis Biotech | |
| Biomarker Analysis of Central Nervous System Tumors | NCT02692898 | Central Nervous... Primary Brain N... Neoplasms, Brai... Cancer of the B... Brain Cancer | - 99 Years | National Institutes of Health Clinical Center (CC) | ||
| Radiosurgery Dose Reduction for Brain Metastases on Immunotherapy (RADREMI): A Prospective Pilot Study | NCT04047602 | Brain Tumor Brain Metastase... Brain Cancer | Reduced Dose SR... | 18 Years - | Indiana University | |
| Randomized Trial Comparing Radiosurgery With vs Without Whole Brain Radiotherapy | NCT00548756 | Brain Cancer | Whole Brain Rad... Observation Questionnaire | 18 Years - | M.D. Anderson Cancer Center | |
| Phase III Study of Rindopepimut/GM-CSF in Patients With Newly Diagnosed Glioblastoma | NCT01480479 | Glioblastoma Small Cell Glio... Giant Cell Glio... Gliosarcoma Glioblastoma Wi... | Rindopepimut (C... Temozolomide KLH | 18 Years - | Celldex Therapeutics | |
| Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors | NCT00870129 | Brain Cancer Glioma | MRI and advance... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Fatigue, Sleep and Cytokines in Primary Brain Tumor (PBT) Patients | NCT00876499 | Brain Cancer | Questionnaire | 18 Years - | M.D. Anderson Cancer Center | |
| A Study to Demonstrate the Safety and Preliminary Efficacy of 18F-FLT in Patients With Solid Tumours or Lymphoma | NCT01065805 | Brain Cancer Cancer Solid Tumor Lymphoma | 18F-FLT | 16 Years - | AHS Cancer Control Alberta | |
| Record Voxel Rate Nonlinear Optical Microscope to Unravel Brain Connectome and Signaling | NCT05943262 | Brain Tumor Brain Cancer | mesoscale nonli... | 20 Years - | National Taiwan University Hospital | |
| A Case-Referent Study of Brain Tumors in Adults | NCT00339300 | Brain Tumors | 18 Years - 90 Years | National Institutes of Health Clinical Center (CC) | ||
| Safety Study of Afatinib for Brain Cancer | NCT02423525 | Brain Cancer | Afatinib | 18 Years - | Saint John's Cancer Institute | |
| 3D Printed Mask for GBM and Brain Mets | NCT04114786 | Brain Cancer | 3D-printed mask Thermoplastic m... | 18 Years - | University Health Network, Toronto | |
| Cambridge Brain Mets Trial 1 | NCT02768337 | Lung Cancer Breast Cancer Brain Cancer Advanced Breast... Advanced Lung C... | Afatinib 2 Gy targeted r... 4 Gy targeted r... | 18 Years - | Cambridge University Hospitals NHS Foundation Trust | |
| Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors | NCT01014767 | Brain Cancer Choroid Plexus ... | Carboplatin Cisplatin Cyclophosphamid... Dactinomycin Doxorubicin Etoposide Irinotecan Leucovorin Methotrexate Temozolomide Vincristine | - | Tufts Medical Center | |
| A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients With Primary and Metastatic Brain Tumors | NCT00001574 | Brain Neoplasm Brain Cancer Brain Tumor, Pr... | - 21 Years | National Institutes of Health Clinical Center (CC) | ||
| Spectroscopy With Surface Coils and Decoupling | NCT00581815 | Adrenal Cortica... Brain Cancer Breast Cancer CNS Cancer Colon Cancer HEENT Cancer Hodgkin's Disea... Kaposi's Sarcom... Liver Cancer Lung Cancer Non-Hodgkin's L... Ovarian Cancer Pancreatic Canc... Prostate Cancer Rectal Cancer Renal Cancer Sarcoma Squamous Cell C... Thyroid Cancer | Proton-decouple... 1H Spectroscopy... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Phase II Sorafenib With Radiation and Temozolomide in Newly Diagnosed Glioblastoma or Gliosarcoma | NCT02599090 | Glioblastoma Gliosarcoma | Temozolomide Radiation Sorafenib | 18 Years - | M.D. Anderson Cancer Center | |
| Surgical Tissue Flap to Bypass the Blood Brain Barrier in GBM | NCT03630289 | Glioblastoma Glioblastoma Mu... GBM Brain Cancer | Tissue autograf... | 18 Years - | Northwell Health | |
| Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S | NCT04430842 | Astrocytoma Brain Cancer Brain Metastase... Bladder Cancer Breast Cancer Cervical Cancer Cholangiocarcin... Colorectal Canc... Esophagus Cance... Gastric Cancer Head and Neck C... Kidney Cancer Liver Cancer Lung Cancer Melanoma Ovarian Cancer Pancreatic Canc... Pleural Mesothe... Prostate Cancer Sarcoma Tongue Cancer Thymic Carcinom... Urinary Tract C... | QBS10072S | 18 Years - | Quadriga Biosciences, Inc. | |
| Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma | NCT03072134 | Glioma Anaplastic Astr... Anaplastic Olig... Anaplastic Olig... Glioblastoma Mu... Astrocytoma, Gr... Astrocytoma, Gr... Brain Cancer | Neural stem cel... | 18 Years - | Northwestern University | |
| A Prospective Cohort Study of Occupational Exposures and Cancer Risk Among Women | NCT00342004 | Lung Cancer Non-Hodgkin Lym... Breast Cancer Stomach Cancer Brain Cancer | 40 Years - 70 Years | National Institutes of Health Clinical Center (CC) | ||
| Re-craniotomy and Complications After Elective Neurosurgery | NCT03910556 | Brain Tumor Brain Metastase... Brain Cancer Brain Neoplasms | Propofol | 18 Years - 75 Years | Chiang Mai University | |
| Natural History of and Specimen Banking for People With Tumors of the Central Nervous System | NCT02851706 | Brain Cancer Brain Tumor Spine Cancer Spine Tumor Neoplasm | No Treatment | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| EGFR Inhibition Using Weekly Erlotinib for Recurrent Malignant Gliomas | NCT01257594 | Brain Cancer | erlotinib Cytoreductive S... | 18 Years - | Columbia University | |
| BP31510 (Ubidecarenone,USP) Nanosuspension for Intravenous Injection to Patients With Solid Tumors | NCT01957735 | Metastatic Canc... Cancer Solid Tumor | BP31510 monothe... BP31510 in comb... | 18 Years - | Berg, LLC | |
| Mind Over Matter for Black and African American Women: A Single Arm Trial Examining Feasibility and Acceptability of a Supportive Intervention | NCT06168825 | Cancer Breast Cancer Brain Cancer Central Nervous... Colorectal Canc... Esophageal Canc... Gynecologic Can... Head and Neck C... Gastrointestina... Genitourinary C... Melanoma Blood Cancer Lung Cancer Acceptance and ... Mind-Body Thera... Psychosocial In... | Mind Over Matte... | 18 Years - | Inova Health Care Services | |
| Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM | NCT05271240 | Glioblastoma Glioblastoma Mu... Glioma, Maligna... GBM Brain Cancer Glioblastoma, I... Glioblastoma Mu... | Repeated Supers... Temozolomide an... | 18 Years - | Northwell Health | |
| A Study of Bevacizumab in Combination With First- or Second-Line Therapy in Subjects With Treated Brain Metastases Due to Non-Squamous NSCLC (PASSPORT) | NCT00312728 | Non-Small Cell ... Brain Neoplasms | bevacizumab First-Line Chem... Second-Line Che... | 18 Years - | Genentech, Inc. | |
| Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab | NCT02330562 | Malignant Gliom... Glioblastoma | MRZ BEV | 18 Years - | Celgene | |
| Bevacizumab in the Radiation Treatment of Recurrent Malignant Glioma | NCT00595322 | Brain Cancer Recurrent Malig... Primary Brain T... | bevacizumab and... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors | NCT04478279 | Glioblastoma Melanoma Stage ... Breast Cancer Prostate Cancer Glioblastoma Mu... GBM Brain Cancer Metastatic Brea... Metastatic Mela... Metastatic Pros... Melanoma Recurr... Prostate Cancer... Recurrent Gliob... Newly Diagnosed... | ST101 Temozolomide Radiation | 18 Years - | Sapience Therapeutics | |
| IDH1 Peptide Vaccine for Recurrent Grade II Glioma | NCT02193347 | Brain Cancer Brain Neoplasm,... Brain Neoplasms... Brain Tumor Cancer of the B... | PEPIDH1M vaccin... Tetanus-Diphthe... Temozolomide | 18 Years - | Duke University | |
| Bevacizumab and Lapatinib in Children With Recurrent or Refractory Ependymoma | NCT00883688 | Brain Cancer Pediatric Cance... | Bevacizumab Lapatinib | - 21 Years | M.D. Anderson Cancer Center | |
| A Phase I Trial Using Combination Irinotecan and Thalidomide for Recurrent CNS Tumors | NCT00251797 | Brain and Nervo... Cancer | Irinotecan Thalidomide | 18 Years - | University of New Mexico | |
| Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT) | NCT01906385 | Glioma | Rhenium Liposom... | 18 Years - | Plus Therapeutics | |
| The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors | NCT05116137 | Glioblastoma Mu... Brain Cancer | Circuit-based r... | 18 Years - | Nova Scotia Health Authority | |
| Trastuzumab Deruxtecan (T-DXd) for People With Brain Cancer | NCT06058988 | Brain Cancer Glioblastoma Metastatic Canc... Leptomeningeal ... Recurrent Gliob... | Trastuzumab der... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor Survivors | NCT00594633 | Brain Tumor Brain Cancer Cns Cancer Cognitive Dysfu... | donepezil and q... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| An Investigational Immuno-therapy Study of Nivolumab Compared to Temozolomide, Each Given With Radiation Therapy, for Newly-diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) | NCT02617589 | Brain Cancer | Nivolumab Temozolomide Radiotherapy | 18 Years - | Bristol-Myers Squibb | |
| Refining and Testing the Electronic Social Network Assessment Program (eSNAP) | NCT03026699 | Brain Cancer | eSNAP Questionnaires | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Genetically-informed Therapies for Patients With Metastatic Cancer | NCT02000739 | Metastatic Canc... | Genetically Inf... | 18 Years - | Dartmouth-Hitchcock Medical Center | |
| Bevacizumab (Avastin) Into the Tumor Resection Cavity in Subjects With Glioblastoma Multiforme at First Recurrence | NCT01526837 | Glioblastoma Mu... | Avastin | 18 Years - | Brain & Spine Surgeons of New York | |
| Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas | NCT04869449 | Glioblastoma Glioblastoma Mu... Glioblastoma Mu... Glioblastoma Mu... | Ketoconazole | 18 Years - | Milton S. Hershey Medical Center | |
| More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery | NCT01445691 | Benign Neoplasm... Brain Cancer Brain Neoplasms... Brain Neoplasms... Brain Tumor, Pr... Brain Tumor, Re... Brain Tumors Intracranial Ne... Neoplasms, Brai... Neoplasms, Intr... Primary Brain N... Primary Maligna... Primary Maligna... Gliomas Glioblastoma | 5-ALA (Gliolan) | 18 Years - 80 Years | Icahn School of Medicine at Mount Sinai | |
| Adjunctive Donepezil Therapy and Genetic Risk Factors of Cognitive Dysfunction in Brain Tumor Survivors | NCT00594633 | Brain Tumor Brain Cancer Cns Cancer Cognitive Dysfu... | donepezil and q... | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Glioblastoma Multiforme (GBM) Proton vs. Intensity Modulated Radiotherapy (IMRT) | NCT01854554 | Brain Cancer | IMPT IMRT Cognitive Tests Questionnaires | 18 Years - | M.D. Anderson Cancer Center | |
| Study of Insulin-like Growth Factor (IGF)-Methotrexate Conjugate in the Treatment of Advanced Tumors Expressing IGF-1R | NCT02045368 | Breast Cancer Brain Cancer Gastrointestina... Genitourinary C... Gynecologic Can... Head and Neck C... Melanoma Thoracic Cancer... | IGF-Methotrexat... | 18 Years - | IGF Oncology, LLC | |
| Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma | NCT00589784 | CNS Cancer Meningioma Intracranial He... Hemangioblastom... Neurofibromatos... | Sunitinib | 18 Years - | Memorial Sloan Kettering Cancer Center | |
| Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma | NCT03223103 | Glioblastoma | Poly-ICLC Tumor Treating ... Peptides | 18 Years - | Albert Einstein College of Medicine | |
| Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM | NCT05271240 | Glioblastoma Glioblastoma Mu... Glioma, Maligna... GBM Brain Cancer Glioblastoma, I... Glioblastoma Mu... | Repeated Supers... Temozolomide an... | 18 Years - | Northwell Health | |
| VAL-083 Phase 3 Study in Temozolomide-Avastin (Bevacizumab) Recurrent GBM | NCT03149575 | Glioblastoma Mu... Glioblastoma Glioma GBM Brain Cancer | VAL-083, Dianhy... Physician's Cho... Physician's Cho... Physician's Cho... | 18 Years - | Kintara Therapeutics, Inc. |
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