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Brief Title: Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors
Official Title: Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors
Study ID: NCT04889742
Brief Summary: This study investiagates deep-regional or superficial hyperthermia to enhance radiotherapy or chemoradiation in patients that suffer recurrent disease after previous radiotherapy.
Detailed Description: patients that present a relapse within the previously irradiated volume can be included in this trial. These patients will receive re-irradiation according to clinical guidelines and hyperthermia as study intervention. According to tumor location hyperthermia can either be performed by microwave or by capacitive devices. The primary endpoint of this study is non-inferiority of re-irradiation compared to the initial course of radiotherapy (calculated as time to local failure).
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Klinik für Radioonkologie und Strahlentherapie, Berlin, , Germany
Name: Sebastian Zschaeck, MD
Affiliation: Charité
Role: PRINCIPAL_INVESTIGATOR