Spots Global Cancer Trial Database for dna methylation
Every month we try and update this database with for dna methylation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
Plasma-based Colorectal Cancer Screening Research & Development | NCT04027790 | Colo-rectal Can... | Epi proColon | 45 Years - 84 Years | Epigenomics, Inc | |
Parental One-carbon Folate and Choline Nutrition Modulates Risk of Off-spring Cancer Development: Human Cohort Study | NCT02266641 | Off-spring Canc... | nutrition couns... multivitamin su... | 21 Years - 40 Years | National Taiwan University Hospital | |
FdCyd and THU for Advanced Solid Tumors | NCT01534598 | Neoplasms | FdCyd + THU | 18 Years - | National Institutes of Health Clinical Center (CC) | |
DNA Methylation for Screening Uterine Cervical Lesions | NCT03960879 | DNA Methylation Uterine Cervica... High Grade Squa... Low Grade Squam... | DNA methylation High-risk HPV TCT | 18 Years - | Peking Union Medical College Hospital | |
DNA Methylation Biomarkers and Metastasis of Gastric Carcinoma | NCT02159339 | Gastric Carcino... | - | Peking University Cancer Hospital & Institute | ||
Developing Novel Circulating Epigenetic Biomarkers for Early Detection of Lung Cancer | NCT04814407 | Lung Cancer | Blood-derived D... | 20 Years - | National Taiwan University Hospital | |
Precision Medicine for Every Child With Cancer | NCT05504772 | Childhood Cance... Childhood Solid... Childhood Brain... Childhood Leuke... Refractory Canc... Relapsed Cancer | Whole Genome Se... RNA seq DNA Methylation Targeted Panel ... High Throughput... Patient Derived... Liquid Biopsy | 0 Years - 25 Years | Australian & New Zealand Children's Haematology/Oncology Group | |
Liquid Biopsy for Early Non-small Lung Cancer Detection | NCT05462795 | Non Small-cell ... | Liquid biopsy f... Liquid biopsy f... Liquid biopsy f... Liquid biopsy f... | 18 Years - | University of Arizona | |
Validation of DNA Methylation Biomarkers for Oral Cancer Detection | NCT02648789 | Oral Cancer Recurrence | 20 Years - 75 Years | Taipei Veterans General Hospital, Taiwan | ||
Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid Samples | NCT05737953 | Pancreatic Neop... DNA Methylation Proteome | cfDNA methylati... | 18 Years - | Changhai Hospital | |
Breast Cancer, Omics, and Precision Medicine | NCT04996836 | Breast Cancer | Next Generation... | 18 Years - | University of Campania "Luigi Vanvitelli" | |
DNA CDO1 and CELF4 Methylation for Endometrial Cancer Screening | NCT05290922 | Endometrial Can... Cancer Screenin... DNA Methylation Testing Accurac... Cervical Cytolo... | DNA methylation... | 18 Years - | Peking Union Medical College Hospital | |
DNA PAX1 and JAM3 Methylation for Cervical Cancer Screening | NCT05290428 | Cervical Cancer Cervical Intrae... DNA Methylation Cancer Screenin... Detection Accur... | DNA methylation... | 18 Years - | Peking Union Medical College Hospital | |
DNA Methylation Biomarkers for Cervical Cancer Screening | NCT02605941 | Cervical Intrae... Cervical Cancer | 20 Years - | iStat Biomedical CO., Ltd. | ||
Validation of DNA Methylation Biomarkers for Oral Cancer Detection | NCT02648789 | Oral Cancer Recurrence | 20 Years - 75 Years | Taipei Veterans General Hospital, Taiwan | ||
PaCIFiC-CUP Classifies Cancer of Unknown Primary | NCT06140992 | Unknown Primary... DNA Methylation | 18 Years - 80 Years | Sun Yat-sen University | ||
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors | NCT02423057 | Neoplasms Solid Tumors | TdCyd | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
DNA Methylation and Cancer Prevention: Duration and Intensity of Exercise | NCT02032628 | DNA Methylation | Exercise | 30 Years - 45 Years | University of Colorado, Boulder | |
PaCIFiC-CUP Classifies Cancer of Unknown Primary | NCT06140992 | Unknown Primary... DNA Methylation | 18 Years - 80 Years | Sun Yat-sen University | ||
Cell-free DNA Methylation for Epithelial Ovarian Cancer | NCT04651946 | Epithelial Ovar... DNA Methylation Benign Ovarian ... Training Set Validation Set Cell-free DNA Liquid Biopsy | DNA methylation... | 18 Years - | Peking Union Medical College Hospital | |
The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal Cancer | NCT03923335 | Colorectal Neop... | DNA methylation... | 40 Years - 70 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
Longitudinal Performance of Epi proColon | NCT03218423 | Colorectal Canc... Colorectal Neop... | Epi proColon | 50 Years - 74 Years | Epigenomics, Inc | |
DNA Methylation Biomarkers and Metastasis of Gastric Carcinoma | NCT02159339 | Gastric Carcino... | - | Peking University Cancer Hospital & Institute | ||
DNA Methylation for Screening Uterine Cervical Lesions | NCT03960879 | DNA Methylation Uterine Cervica... High Grade Squa... Low Grade Squam... | DNA methylation High-risk HPV TCT | 18 Years - | Peking Union Medical College Hospital | |
Cell-free DNA Methylation for Epithelial Ovarian Cancer | NCT04651946 | Epithelial Ovar... DNA Methylation Benign Ovarian ... Training Set Validation Set Cell-free DNA Liquid Biopsy | DNA methylation... | 18 Years - | Peking Union Medical College Hospital | |
Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity | NCT05791149 | Oral Squamous C... Maxillo-facial ... Biomarkers Saliva DNA Methylation Epigenetics | saliva tube | 18 Years - | Centre Hospitalier Universitaire, Amiens | |
5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer | NCT00359606 | Neoplasms | 5-Fluoro-2-Deox... Laboratory Biom... Pharmacological... Tetrahydrouridi... | 18 Years - | City of Hope Medical Center | |
Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for Upper Tract Urothelial Carcinoma Detection | NCT04948528 | Upper Tract Uro... | Active Comparat... Active Comparat... | 18 Years - | AnchorDx Medical Co., Ltd. | |
The Role of FAM19A4 and Hsa-mir-124 Methylation in Predicting Prognosis of Untreated Cervical Intraepithelial Neoplasia 2 (CIN 2) | NCT05624827 | Cervical Intrae... DNA Methylation | Testing DNA met... | 20 Years - 36 Years | University Medical Centre Maribor | |
DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct Stricture | NCT04568512 | Cholangiocarcin... Biliary Strictu... DNA Methylation Brush Cytology | Control Cholangiocarcin... | 18 Years - | Mahidol University | |
Epigenetic Changes in Hepatocellular Carcinoma Developed After Direct Acting Antiviral Therapy for Chronic Hepatitis C | NCT04220151 | Hepatocellular ... | DNA methylation | 20 Years - 75 Years | Assiut University | |
The Application of Serum DNA Methylation for Patients With HCC | NCT05764551 | Hepatocellular ... | Serum DNA methy... | 20 Years - | Chiayi Christian Hospital | |
Breast Cancer, Omics, and Precision Medicine | NCT04996836 | Breast Cancer | Next Generation... | 18 Years - | University of Campania "Luigi Vanvitelli" | |
Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid Samples | NCT05737953 | Pancreatic Neop... DNA Methylation Proteome | cfDNA methylati... | 18 Years - | Changhai Hospital | |
Novel Urine-Based DNA Methylation Biomarkers for Urothelial Bladder Carcinoma Detection in Patients With Hematuria | NCT05362539 | Bladder Cancer | Cystoscopy Computed tomogr... DNA hypermethyl... Urine cytology | 18 Years - | Mansoura University | |
Novel Urine-Based DNA Methylation Biomarkers for Urothelial Bladder Carcinoma Detection in Patients With Hematuria | NCT05362539 | Bladder Cancer | Cystoscopy Computed tomogr... DNA hypermethyl... Urine cytology | 18 Years - | Mansoura University | |
Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for Upper Tract Urothelial Carcinoma Detection | NCT04948528 | Upper Tract Uro... | Active Comparat... Active Comparat... | 18 Years - | AnchorDx Medical Co., Ltd. | |
Cell-free DNA Methylation for Endometrial Cancer | NCT04651738 | Endometrial Can... Liquid Biopsy DNA Methylation Cervical Cytolo... Diagnostic Accu... Training Set Validation Set | DNA methylation... | 18 Years - | Peking Union Medical College Hospital | |
Host DNA Methylation for Endometrial Cancer Screening | NCT05290415 | Cancer Screenin... Endometrial Can... DNA Methylation Cervical Cytolo... Liquid Biopsy Cohort Study | DNA methylation... | 18 Years - | Peking Union Medical College Hospital | |
Precision Medicine for Every Child With Cancer | NCT05504772 | Childhood Cance... Childhood Solid... Childhood Brain... Childhood Leuke... Refractory Canc... Relapsed Cancer | Whole Genome Se... RNA seq DNA Methylation Targeted Panel ... High Throughput... Patient Derived... Liquid Biopsy | 0 Years - 25 Years | Australian & New Zealand Children's Haematology/Oncology Group | |
Self Collected Sampling in Non-attendees Cervical Cancer Screening: DNA Test and Molecular Triage for HPV Positive Women | NCT03183700 | Cervical Cancer | Self sampling d... Cervical ThinPr... | 34 Years - 64 Years | Cancer Prevention and Research Institute, Italy | |
Optimization of Cervical Cancer Screening Among Women Living With HIV in Latin American Countries | NCT06002126 | Cervix Cancer HPV Infection Cervical High G... HIV Infections | Xpert HPV S5 DNA methylat... | 25 Years - 65 Years | Weill Medical College of Cornell University | |
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors | NCT02423057 | Neoplasms Solid Tumors | TdCyd | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity | NCT05791149 | Oral Squamous C... Maxillo-facial ... Biomarkers Saliva DNA Methylation Epigenetics | saliva tube | 18 Years - | Centre Hospitalier Universitaire, Amiens | |
DNA Methylation and Cancer Prevention: Duration and Intensity of Exercise | NCT02032628 | DNA Methylation | Exercise | 30 Years - 45 Years | University of Colorado, Boulder | |
Liquid Biopsy for Early Non-small Lung Cancer Detection | NCT05462795 | Non Small-cell ... | Liquid biopsy f... Liquid biopsy f... Liquid biopsy f... Liquid biopsy f... | 18 Years - | University of Arizona | |
DNA Mutation Detection in Circulating Tumor DNA and Tissue by mmADPS for Pancreatic Cancer | NCT05604573 | Pancreatic Canc... | cell free DNA i... | 18 Years - | Seoul National University Hospital | |
DNA Methylation Biomarkers and Metastasis of Gastric Carcinoma | NCT02159339 | Gastric Carcino... | - | Peking University Cancer Hospital & Institute | ||
Detection of Methylated Reprimo in Plasma for Asymptomatic Gastric Cancer | NCT01774266 | Early Gastric C... | 40 Years - 70 Years | Pontificia Universidad Catolica de Chile | ||
Development of Free DNA Multi-target Methylated PCR for Auxiliary Diagnosis of Gastric Cancer | NCT05336058 | Stomach Cancer | No intervention | 18 Years - | Singlera Genomics Inc. | |
DNA CDO1 and CELF4 Methylation for Endometrial Cancer Screening | NCT05290922 | Endometrial Can... Cancer Screenin... DNA Methylation Testing Accurac... Cervical Cytolo... | DNA methylation... | 18 Years - | Peking Union Medical College Hospital | |
Diet and Nutrition Pilot Study for Chinese Adolescents and Their Mothers | NCT01517139 | Methylation Body Compositio... Physical Activi... Puberty | 15 Years - 45 Years | National Institutes of Health Clinical Center (CC) | ||
Non-Invasive ctDNA Methylation Detection for Lung Nodule Patients | NCT03685669 | Lung Nodule | 18 Years - | Shanghai Chest Hospital | ||
DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct Stricture | NCT04568512 | Cholangiocarcin... Biliary Strictu... DNA Methylation Brush Cytology | Control Cholangiocarcin... | 18 Years - | Mahidol University | |
Diet and Nutrition Pilot Study for Chinese Adolescents and Their Mothers | NCT01517139 | Methylation Body Compositio... Physical Activi... Puberty | 15 Years - 45 Years | National Institutes of Health Clinical Center (CC) | ||
5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer | NCT00359606 | Neoplasms | 5-Fluoro-2-Deox... Laboratory Biom... Pharmacological... Tetrahydrouridi... | 18 Years - | City of Hope Medical Center | |
Stage II/III Colorectal Cancer Recurrence | NCT06314958 | Colorectal Canc... Colorectal Aden... Colorectal Canc... Colorectal Canc... Colorectal Canc... | CENSURE | 18 Years - | City of Hope Medical Center | |
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus | NCT00431756 | Barrett Esophag... Esophageal Neop... Gastroesophagea... | 18 Years - 95 Years | Johns Hopkins University | ||
Exploration of DNA Methylation as a Marker for Early Detection of High Grade Serous Epithelial Ovarian Cancer | NCT03622385 | Epithelial Ovar... | DNA Methylation | 18 Years - | Baylor Research Institute | |
Using a Blood Test to Monitor Metastatic Breast Cancer Treatment | NCT05804578 | Metastatic Brea... | 18 Years - | Queen's University | ||
Cell-free DNA Methylation for Endometrial Cancer | NCT04651738 | Endometrial Can... Liquid Biopsy DNA Methylation Cervical Cytolo... Diagnostic Accu... Training Set Validation Set | DNA methylation... | 18 Years - | Peking Union Medical College Hospital | |
The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal Cancer | NCT03923335 | Colorectal Neop... | DNA methylation... | 40 Years - 70 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
Plasma-based Colorectal Cancer Screening Research & Development | NCT04027790 | Colo-rectal Can... | Epi proColon | 45 Years - 84 Years | Epigenomics, Inc |