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Spots Global Cancer Trial Database for dna methylation

Every month we try and update this database with for dna methylation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Plasma-based Colorectal Cancer Screening Research & DevelopmentNCT04027790
Colo-rectal Can...
Epi proColon
45 Years - 84 YearsEpigenomics, Inc
Parental One-carbon Folate and Choline Nutrition Modulates Risk of Off-spring Cancer Development: Human Cohort StudyNCT02266641
Off-spring Canc...
nutrition couns...
multivitamin su...
21 Years - 40 YearsNational Taiwan University Hospital
FdCyd and THU for Advanced Solid TumorsNCT01534598
Neoplasms
FdCyd + THU
18 Years - National Institutes of Health Clinical Center (CC)
DNA Methylation for Screening Uterine Cervical LesionsNCT03960879
DNA Methylation
Uterine Cervica...
High Grade Squa...
Low Grade Squam...
DNA methylation
High-risk HPV
TCT
18 Years - Peking Union Medical College Hospital
DNA Methylation Biomarkers and Metastasis of Gastric CarcinomaNCT02159339
Gastric Carcino...
- Peking University Cancer Hospital & Institute
Developing Novel Circulating Epigenetic Biomarkers for Early Detection of Lung CancerNCT04814407
Lung Cancer
Blood-derived D...
20 Years - National Taiwan University Hospital
Precision Medicine for Every Child With CancerNCT05504772
Childhood Cance...
Childhood Solid...
Childhood Brain...
Childhood Leuke...
Refractory Canc...
Relapsed Cancer
Whole Genome Se...
RNA seq
DNA Methylation
Targeted Panel ...
High Throughput...
Patient Derived...
Liquid Biopsy
0 Years - 25 YearsAustralian & New Zealand Children's Haematology/Oncology Group
Liquid Biopsy for Early Non-small Lung Cancer DetectionNCT05462795
Non Small-cell ...
Liquid biopsy f...
Liquid biopsy f...
Liquid biopsy f...
Liquid biopsy f...
18 Years - University of Arizona
Validation of DNA Methylation Biomarkers for Oral Cancer DetectionNCT02648789
Oral Cancer
Recurrence
20 Years - 75 YearsTaipei Veterans General Hospital, Taiwan
Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid SamplesNCT05737953
Pancreatic Neop...
DNA Methylation
Proteome
cfDNA methylati...
18 Years - Changhai Hospital
Breast Cancer, Omics, and Precision MedicineNCT04996836
Breast Cancer
Next Generation...
18 Years - University of Campania "Luigi Vanvitelli"
DNA CDO1 and CELF4 Methylation for Endometrial Cancer ScreeningNCT05290922
Endometrial Can...
Cancer Screenin...
DNA Methylation
Testing Accurac...
Cervical Cytolo...
DNA methylation...
18 Years - Peking Union Medical College Hospital
DNA PAX1 and JAM3 Methylation for Cervical Cancer ScreeningNCT05290428
Cervical Cancer
Cervical Intrae...
DNA Methylation
Cancer Screenin...
Detection Accur...
DNA methylation...
18 Years - Peking Union Medical College Hospital
DNA Methylation Biomarkers for Cervical Cancer ScreeningNCT02605941
Cervical Intrae...
Cervical Cancer
20 Years - iStat Biomedical CO., Ltd.
Validation of DNA Methylation Biomarkers for Oral Cancer DetectionNCT02648789
Oral Cancer
Recurrence
20 Years - 75 YearsTaipei Veterans General Hospital, Taiwan
PaCIFiC-CUP Classifies Cancer of Unknown PrimaryNCT06140992
Unknown Primary...
DNA Methylation
18 Years - 80 YearsSun Yat-sen University
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid TumorsNCT02423057
Neoplasms
Solid Tumors
TdCyd
18 Years - 120 YearsNational Institutes of Health Clinical Center (CC)
DNA Methylation and Cancer Prevention: Duration and Intensity of ExerciseNCT02032628
DNA Methylation
Exercise
30 Years - 45 YearsUniversity of Colorado, Boulder
PaCIFiC-CUP Classifies Cancer of Unknown PrimaryNCT06140992
Unknown Primary...
DNA Methylation
18 Years - 80 YearsSun Yat-sen University
Cell-free DNA Methylation for Epithelial Ovarian CancerNCT04651946
Epithelial Ovar...
DNA Methylation
Benign Ovarian ...
Training Set
Validation Set
Cell-free DNA
Liquid Biopsy
DNA methylation...
18 Years - Peking Union Medical College Hospital
The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal CancerNCT03923335
Colorectal Neop...
DNA methylation...
40 Years - 70 YearsSixth Affiliated Hospital, Sun Yat-sen University
Longitudinal Performance of Epi proColonNCT03218423
Colorectal Canc...
Colorectal Neop...
Epi proColon
50 Years - 74 YearsEpigenomics, Inc
DNA Methylation Biomarkers and Metastasis of Gastric CarcinomaNCT02159339
Gastric Carcino...
- Peking University Cancer Hospital & Institute
DNA Methylation for Screening Uterine Cervical LesionsNCT03960879
DNA Methylation
Uterine Cervica...
High Grade Squa...
Low Grade Squam...
DNA methylation
High-risk HPV
TCT
18 Years - Peking Union Medical College Hospital
Cell-free DNA Methylation for Epithelial Ovarian CancerNCT04651946
Epithelial Ovar...
DNA Methylation
Benign Ovarian ...
Training Set
Validation Set
Cell-free DNA
Liquid Biopsy
DNA methylation...
18 Years - Peking Union Medical College Hospital
Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral CavityNCT05791149
Oral Squamous C...
Maxillo-facial ...
Biomarkers
Saliva
DNA Methylation
Epigenetics
saliva tube
18 Years - Centre Hospitalier Universitaire, Amiens
5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced CancerNCT00359606
Neoplasms
5-Fluoro-2-Deox...
Laboratory Biom...
Pharmacological...
Tetrahydrouridi...
18 Years - City of Hope Medical Center
Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for Upper Tract Urothelial Carcinoma DetectionNCT04948528
Upper Tract Uro...
Active Comparat...
Active Comparat...
18 Years - AnchorDx Medical Co., Ltd.
The Role of FAM19A4 and Hsa-mir-124 Methylation in Predicting Prognosis of Untreated Cervical Intraepithelial Neoplasia 2 (CIN 2)NCT05624827
Cervical Intrae...
DNA Methylation
Testing DNA met...
20 Years - 36 YearsUniversity Medical Centre Maribor
DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct StrictureNCT04568512
Cholangiocarcin...
Biliary Strictu...
DNA Methylation
Brush Cytology
Control
Cholangiocarcin...
18 Years - Mahidol University
Epigenetic Changes in Hepatocellular Carcinoma Developed After Direct Acting Antiviral Therapy for Chronic Hepatitis CNCT04220151
Hepatocellular ...
DNA methylation
20 Years - 75 YearsAssiut University
The Application of Serum DNA Methylation for Patients With HCCNCT05764551
Hepatocellular ...
Serum DNA methy...
20 Years - Chiayi Christian Hospital
Breast Cancer, Omics, and Precision MedicineNCT04996836
Breast Cancer
Next Generation...
18 Years - University of Campania "Luigi Vanvitelli"
Construction of Molecular Diagnostic Marker Model for Pancreatic Cystic Tumors Based on Pancreatic Cystic Fluid SamplesNCT05737953
Pancreatic Neop...
DNA Methylation
Proteome
cfDNA methylati...
18 Years - Changhai Hospital
Novel Urine-Based DNA Methylation Biomarkers for Urothelial Bladder Carcinoma Detection in Patients With HematuriaNCT05362539
Bladder Cancer
Cystoscopy
Computed tomogr...
DNA hypermethyl...
Urine cytology
18 Years - Mansoura University
Novel Urine-Based DNA Methylation Biomarkers for Urothelial Bladder Carcinoma Detection in Patients With HematuriaNCT05362539
Bladder Cancer
Cystoscopy
Computed tomogr...
DNA hypermethyl...
Urine cytology
18 Years - Mansoura University
Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for Upper Tract Urothelial Carcinoma DetectionNCT04948528
Upper Tract Uro...
Active Comparat...
Active Comparat...
18 Years - AnchorDx Medical Co., Ltd.
Cell-free DNA Methylation for Endometrial CancerNCT04651738
Endometrial Can...
Liquid Biopsy
DNA Methylation
Cervical Cytolo...
Diagnostic Accu...
Training Set
Validation Set
DNA methylation...
18 Years - Peking Union Medical College Hospital
Host DNA Methylation for Endometrial Cancer ScreeningNCT05290415
Cancer Screenin...
Endometrial Can...
DNA Methylation
Cervical Cytolo...
Liquid Biopsy
Cohort Study
DNA methylation...
18 Years - Peking Union Medical College Hospital
Precision Medicine for Every Child With CancerNCT05504772
Childhood Cance...
Childhood Solid...
Childhood Brain...
Childhood Leuke...
Refractory Canc...
Relapsed Cancer
Whole Genome Se...
RNA seq
DNA Methylation
Targeted Panel ...
High Throughput...
Patient Derived...
Liquid Biopsy
0 Years - 25 YearsAustralian & New Zealand Children's Haematology/Oncology Group
Self Collected Sampling in Non-attendees Cervical Cancer Screening: DNA Test and Molecular Triage for HPV Positive WomenNCT03183700
Cervical Cancer
Self sampling d...
Cervical ThinPr...
34 Years - 64 YearsCancer Prevention and Research Institute, Italy
Optimization of Cervical Cancer Screening Among Women Living With HIV in Latin American CountriesNCT06002126
Cervix Cancer
HPV Infection
Cervical High G...
HIV Infections
Xpert HPV
S5 DNA methylat...
25 Years - 65 YearsWeill Medical College of Cornell University
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid TumorsNCT02423057
Neoplasms
Solid Tumors
TdCyd
18 Years - 120 YearsNational Institutes of Health Clinical Center (CC)
Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral CavityNCT05791149
Oral Squamous C...
Maxillo-facial ...
Biomarkers
Saliva
DNA Methylation
Epigenetics
saliva tube
18 Years - Centre Hospitalier Universitaire, Amiens
DNA Methylation and Cancer Prevention: Duration and Intensity of ExerciseNCT02032628
DNA Methylation
Exercise
30 Years - 45 YearsUniversity of Colorado, Boulder
Liquid Biopsy for Early Non-small Lung Cancer DetectionNCT05462795
Non Small-cell ...
Liquid biopsy f...
Liquid biopsy f...
Liquid biopsy f...
Liquid biopsy f...
18 Years - University of Arizona
DNA Mutation Detection in Circulating Tumor DNA and Tissue by mmADPS for Pancreatic CancerNCT05604573
Pancreatic Canc...
cell free DNA i...
18 Years - Seoul National University Hospital
DNA Methylation Biomarkers and Metastasis of Gastric CarcinomaNCT02159339
Gastric Carcino...
- Peking University Cancer Hospital & Institute
Detection of Methylated Reprimo in Plasma for Asymptomatic Gastric CancerNCT01774266
Early Gastric C...
40 Years - 70 YearsPontificia Universidad Catolica de Chile
Development of Free DNA Multi-target Methylated PCR for Auxiliary Diagnosis of Gastric CancerNCT05336058
Stomach Cancer
No intervention
18 Years - Singlera Genomics Inc.
DNA CDO1 and CELF4 Methylation for Endometrial Cancer ScreeningNCT05290922
Endometrial Can...
Cancer Screenin...
DNA Methylation
Testing Accurac...
Cervical Cytolo...
DNA methylation...
18 Years - Peking Union Medical College Hospital
Diet and Nutrition Pilot Study for Chinese Adolescents and Their MothersNCT01517139
Methylation
Body Compositio...
Physical Activi...
Puberty
15 Years - 45 YearsNational Institutes of Health Clinical Center (CC)
Non-Invasive ctDNA Methylation Detection for Lung Nodule PatientsNCT03685669
Lung Nodule
18 Years - Shanghai Chest Hospital
DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct StrictureNCT04568512
Cholangiocarcin...
Biliary Strictu...
DNA Methylation
Brush Cytology
Control
Cholangiocarcin...
18 Years - Mahidol University
Diet and Nutrition Pilot Study for Chinese Adolescents and Their MothersNCT01517139
Methylation
Body Compositio...
Physical Activi...
Puberty
15 Years - 45 YearsNational Institutes of Health Clinical Center (CC)
5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced CancerNCT00359606
Neoplasms
5-Fluoro-2-Deox...
Laboratory Biom...
Pharmacological...
Tetrahydrouridi...
18 Years - City of Hope Medical Center
Stage II/III Colorectal Cancer RecurrenceNCT06314958
Colorectal Canc...
Colorectal Aden...
Colorectal Canc...
Colorectal Canc...
Colorectal Canc...
CENSURE
18 Years - City of Hope Medical Center
Novel Biomarkers in the Neoplastic Progression of Barrett's EsophagusNCT00431756
Barrett Esophag...
Esophageal Neop...
Gastroesophagea...
18 Years - 95 YearsJohns Hopkins University
Exploration of DNA Methylation as a Marker for Early Detection of High Grade Serous Epithelial Ovarian CancerNCT03622385
Epithelial Ovar...
DNA Methylation
18 Years - Baylor Research Institute
Using a Blood Test to Monitor Metastatic Breast Cancer TreatmentNCT05804578
Metastatic Brea...
18 Years - Queen's University
Cell-free DNA Methylation for Endometrial CancerNCT04651738
Endometrial Can...
Liquid Biopsy
DNA Methylation
Cervical Cytolo...
Diagnostic Accu...
Training Set
Validation Set
DNA methylation...
18 Years - Peking Union Medical College Hospital
The Predictive Value of Guangzhou Panel for Recurrence in Early-stage Colorectal CancerNCT03923335
Colorectal Neop...
DNA methylation...
40 Years - 70 YearsSixth Affiliated Hospital, Sun Yat-sen University
Plasma-based Colorectal Cancer Screening Research & DevelopmentNCT04027790
Colo-rectal Can...
Epi proColon
45 Years - 84 YearsEpigenomics, Inc
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