Spots Global Cancer Trial Database for epigenetics
Every month we try and update this database with for epigenetics cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Epigenetics and Psychoneurologic Symptoms in Women With Breast Cancer | NCT01411943 | Breast Cancer | 21 Years - 81 Years | Virginia Commonwealth University | ||
| FdCyd and THU for Advanced Solid Tumors | NCT01534598 | Neoplasms | FdCyd + THU | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Lung Cancer Diagnosis by Detecting Epigenetic Imprinting Alterations in Bronchoalveolar Lavage | NCT05707585 | Lung Cancer | Quantitative Ch... | 18 Years - 75 Years | The Second Affiliated Hospital of Dalian Medical University | |
| A Phase 1/2 Study to Evaluate OTX-2002 in Patients With Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association With the MYC Oncogene | NCT05497453 | Hepatocellular ... Solid Tumor Hepatocellular ... Hepatocellular ... Hepatocellular ... Liver Cancer Liver, Cancer o... | OTX-2002 Tyrosine kinase... Tyrosine kinase... Checkpoint Inhi... | 18 Years - | Omega Therapeutics | |
| Immune Resistance Interrogation Study | NCT04243720 | Cancer Solid Tumor Metastatic Canc... Immune Resistan... | 18 Years - | University Health Network, Toronto | ||
| A Study of ZEN003694 in Patients With Metastatic Castration-Resistant Prostate Cancer | NCT02705469 | Metastatic Cast... | ZEN003694 | 18 Years - | Zenith Epigenetics | |
| Epigenetics and Psychoneurologic Symptoms in Women With Breast Cancer | NCT01411943 | Breast Cancer | 21 Years - 81 Years | Virginia Commonwealth University | ||
| Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet | NCT04965129 | Lung Cancer | Placebo Fish oil | 20 Years - 90 Years | Universidade Federal do Rio de Janeiro | |
| Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors | NCT02423057 | Neoplasms Solid Tumors | TdCyd | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
| DNA Methylation and Cancer Prevention: Duration and Intensity of Exercise | NCT02032628 | DNA Methylation | Exercise | 30 Years - 45 Years | University of Colorado, Boulder | |
| Methylation Level of SHOX2 in Endobronchial Ultrasound With Real-time Guided Transbronchial Needle Aspiration for Lung Cancer Staging | NCT01653002 | Lung Cancer Wit... | No intervention | 18 Years - 90 Years | University Hospital, Essen | |
| An Early Phase Study of Abraxane Combined With Phenelzine Sulfate in Patients With Metastatic or Advanced Breast Cancer | NCT03505528 | Metastatic Brea... | Nanoparticle al... Phenelzine Sulf... | 18 Years - | EpiAxis Therapeutics | |
| Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity | NCT05791149 | Oral Squamous C... Maxillo-facial ... Biomarkers Saliva DNA Methylation Epigenetics | saliva tube | 18 Years - | Centre Hospitalier Universitaire, Amiens | |
| 5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer | NCT00359606 | Neoplasms | 5-Fluoro-2-Deox... Laboratory Biom... Pharmacological... Tetrahydrouridi... | 18 Years - | City of Hope Medical Center | |
| Offspring Born to Mothers With Polycystic Ovary Syndrome in Guangzhou Cohort Study | NCT03742011 | PCOS Offspring, Adul... Hyperandrogenis... Epigenetics Insulin Resista... Endocrine Disor... Metabolic Distu... | - 18 Years | Guangzhou Women and Children's Medical Center | ||
| Genetic Testing in Upper Tract Urothelial Carcinoma (UTUC): the Epicheck Study | NCT04702347 | Urologic Cancer Urologic Neopla... | Urine biomarker | 18 Years - | Fundacio Puigvert | |
| RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Doublet Regimens (QUADRUPLE THREAT) | NCT02489903 | Small Cell Carc... Carcinoma, Non-... Neuroendocrine ... Ovarian Epithel... | RRx-001 Cisplatin Etoposide Carboplatin Irinotecan Vinorelbine Doxil Gemcitabine Taxane Paclitaxel Nab-Paclitaxel Pemetrexed | 18 Years - | EpicentRx, Inc. | |
| Lung Cancer Diagnosis by Detecting Epigenetic Imprinting Alterations in Bronchoalveolar Lavage | NCT05707585 | Lung Cancer | Quantitative Ch... | 18 Years - 75 Years | The Second Affiliated Hospital of Dalian Medical University | |
| Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies | NCT03682029 | Myelodysplastic... Chronic Myelomo... Cytopenia | Vitamin C (asco... Placebo | 18 Years - | Rigshospitalet, Denmark | |
| Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies | NCT03682029 | Myelodysplastic... Chronic Myelomo... Cytopenia | Vitamin C (asco... Placebo | 18 Years - | Rigshospitalet, Denmark | |
| Biomarkers for Breast Cancer Risk in African American Women | NCT01736306 | Breast Cancer | 10 Years - 50 Years | National Institutes of Health Clinical Center (CC) | ||
| Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet | NCT04965129 | Lung Cancer | Placebo Fish oil | 20 Years - 90 Years | Universidade Federal do Rio de Janeiro | |
| Epigenetic Changes in Hepatocellular Carcinoma Developed After Direct Acting Antiviral Therapy for Chronic Hepatitis C | NCT04220151 | Hepatocellular ... | DNA methylation | 20 Years - 75 Years | Assiut University | |
| Study to Assess the Efficacy and Safety of the Epigenetic Modifying Effects of CC-486 (Oral Azacitidine) in Combination With Fulvestrant | NCT02374099 | Breast Neoplasm... | CC-486 Fulvestrant | 18 Years - | Celgene | |
| Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors | NCT02423057 | Neoplasms Solid Tumors | TdCyd | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
| Epigenetic Biomarkers in the Saliva for the Diagnosis of Squamous Cells Carcinoma of the Oral Cavity | NCT05791149 | Oral Squamous C... Maxillo-facial ... Biomarkers Saliva DNA Methylation Epigenetics | saliva tube | 18 Years - | Centre Hospitalier Universitaire, Amiens | |
| DNA Methylation and Cancer Prevention: Duration and Intensity of Exercise | NCT02032628 | DNA Methylation | Exercise | 30 Years - 45 Years | University of Colorado, Boulder | |
| Proteomic-Based Profiling of Lymphomas: Chromatin Proteomics; Composition and Modification of Histone and Non-Histone Chromosomal Proteins | NCT01563874 | Lymphoma Lymphoid Hyperp... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| Ascorbic Acid Levels in MDS, AML, and CMML Patients | NCT03526666 | Myelodysplastic... Acute Myeloid L... Chronic Myelomo... MDS AML CMML | Peripheral bloo... | 18 Years - | Van Andel Research Institute | |
| Biomarkers for Breast Cancer Risk in African American Women | NCT01736306 | Breast Cancer | 10 Years - 50 Years | National Institutes of Health Clinical Center (CC) | ||
| Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies | NCT03682029 | Myelodysplastic... Chronic Myelomo... Cytopenia | Vitamin C (asco... Placebo | 18 Years - | Rigshospitalet, Denmark | |
| Supplementation of n-3 PUFA in the Modulation of Lean Mass in Patients With Lung Cancer Receiving a High-protein Diet | NCT04965129 | Lung Cancer | Placebo Fish oil | 20 Years - 90 Years | Universidade Federal do Rio de Janeiro | |
| Genetic Testing in Upper Tract Urothelial Carcinoma (UTUC): the Epicheck Study | NCT04702347 | Urologic Cancer Urologic Neopla... | Urine biomarker | 18 Years - | Fundacio Puigvert | |
| A Multi-omics Study of Metastatic Prostate Cancer (MOSMPCA) | NCT04660617 | Prostate Cancer... | 40 Years - | West China Hospital | ||
| Multi-Omic Assessment of Squamous Cell Cancers Receiving Systemic Therapy | NCT03712566 | Cancer Esophagus Squam... Squamous Cell C... Anal Canal Squa... Metastatic Canc... | 18 Years - | University Health Network, Toronto | ||
| 5-Fluoro-2'-Deoxcyctidine and Tetrahydrouridine to Treat Patients With Advanced Cancer | NCT00359606 | Neoplasms | 5-Fluoro-2-Deox... Laboratory Biom... Pharmacological... Tetrahydrouridi... | 18 Years - | City of Hope Medical Center | |
| Study to Assess the Efficacy and Safety of the Epigenetic Modifying Effects of CC-486 (Oral Azacitidine) in Combination With Fulvestrant | NCT02374099 | Breast Neoplasm... | CC-486 Fulvestrant | 18 Years - | Celgene | |
| Proteomic-Based Profiling of Lymphomas: Chromatin Proteomics; Composition and Modification of Histone and Non-Histone Chromosomal Proteins | NCT01563874 | Lymphoma Lymphoid Hyperp... | 18 Years - | National Institutes of Health Clinical Center (CC) | ||
| An Early Phase Study of Abraxane Combined With Phenelzine Sulfate in Patients With Metastatic or Advanced Breast Cancer | NCT03505528 | Metastatic Brea... | Nanoparticle al... Phenelzine Sulf... | 18 Years - | EpiAxis Therapeutics |
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