Spots Global Cancer Trial Database for down syndrome

Every month we try and update this database with for down syndrome cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Neurocognitive and Psychosocial Outcomes in Survivors of Childhood Leukemia With Down Syndrome	NCT02859389	Leukemia Down Syndrome		-	St. Jude Children's Research Hospital
ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016	NCT03286634	Down Syndrome Acute Lymphobla... Childhood Cance...	Daunorubicin Prednisolone Vincristine Epirubicin E-coli L-aspara... 6-Mercaptopurin... Methotrexate Hydrocortisone Cytarabine Cyclophosphamid...	0 Years - 20 Years	National Hospital Organization Nagoya Medical Center
Risk-Adapted Chemotherapy in Treating Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia or Localized B-Lineage Lymphoblastic Lymphoma	NCT01190930	Acute Lymphobla... Adult B Lymphob... Ann Arbor Stage... Ann Arbor Stage... Childhood B Acu... Childhood B Acu... Childhood B Lym... Down Syndrome Hypodiploid B A... Philadelphia Ch...	Cyclophosphamid... Cytarabine Dexamethasone Doxorubicin Hyd... Laboratory Biom... Leucovorin Calc... Mercaptopurine Methotrexate Pegaspargase Quality-of-Life... Questionnaire A... Thioguanine Vincristine Sul...	1 Year - 30 Years	Children's Oncology Group
Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome	NCT02521493	Acute Myeloid L... Down Syndrome Myelodysplastic... Myeloid Leukemi... Myeloproliferat...	Asparaginase Asparaginase Er... Cytarabine Daunorubicin Hy... Etoposide Laboratory Biom... Mitoxantrone Hy... Thioguanine	91 Days - 3 Years	Children's Oncology Group
A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia	NCT03914625	B Acute Lymphob... B Lymphoblastic... Down Syndrome	Asparaginase Er... Blinatumomab Cyclophosphamid... Cytarabine Dexamethasone Doxorubicin Hyd... Leucovorin Calc... Mercaptopurine Mercaptopurine ... Methotrexate Pegaspargase Prednisolone Prednisone Radiation Thera... Radiation Thera... Thioguanine Vincristine Sul...	365 Days - 31 Years	National Cancer Institute (NCI)
Parent and Infant Inter(X)Action Intervention (PIXI)	NCT03836300	Fragile X Syndr... Angelman Syndro... Prader-Willi Sy... Dup15Q Syndrome Duchenne Muscul... Phelan-McDermid... Rett Syndrome Smith Magenis S... Williams Syndro... Turner Syndrome Klinefelter Syn... Chromosome 22q1... Tuberous Sclero... Down Syndrome	Parent-Infant I...	- 99 Years	RTI International
A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia	NCT03914625	B Acute Lymphob... B Lymphoblastic... Down Syndrome	Asparaginase Er... Blinatumomab Cyclophosphamid... Cytarabine Dexamethasone Doxorubicin Hyd... Leucovorin Calc... Mercaptopurine Mercaptopurine ... Methotrexate Pegaspargase Prednisolone Prednisone Radiation Thera... Radiation Thera... Thioguanine Vincristine Sul...	365 Days - 31 Years	National Cancer Institute (NCI)
ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016	NCT03286634	Down Syndrome Acute Lymphobla... Childhood Cance...	Daunorubicin Prednisolone Vincristine Epirubicin E-coli L-aspara... 6-Mercaptopurin... Methotrexate Hydrocortisone Cytarabine Cyclophosphamid...	0 Years - 20 Years	National Hospital Organization Nagoya Medical Center
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)	NCT04546399	Down Syndrome Recurrent B Acu...	3-Dimensional C... Blinatumomab Cyclophosphamid... Cytarabine Dexamethasone Etoposide Hydrocortisone ... Leucovorin Calc... Mercaptopurine Methotrexate Nivolumab Pegaspargase Thioguanine Vincristine Sul...	1 Year - 30 Years	National Cancer Institute (NCI)
Neurocognitive and Psychosocial Outcomes in Survivors of Childhood Leukemia With Down Syndrome	NCT02859389	Leukemia Down Syndrome		-	St. Jude Children's Research Hospital
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia	NCT05702645	B Acute Lymphob... Down Syndrome Myeloid Leukemi...	Biospecimen Col... Clinical Evalua... Questionnaire A... Survey Administ...	6 Years - 39 Years	Children's Oncology Group

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