Spots Global Cancer Trial Database for metastatic malignant neoplasm in the leptomeninges

Every month we try and update this database with for metastatic malignant neoplasm in the leptomeninges cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Trotabresib in Combination With Vinorelbine and Radiation Therapy for the Treatment of HER2+ Breast Cancer With Central Nervous System or Leptomeningeal Metastasis	NCT06137651	Breast Carcinom... Metastatic Mali... Metastatic Mali...	Biospecimen Col... Computed Tomogr... Magnetic Resona... Radiation Thera... Resection Trotabresib Vinorelbine	18 Years -	Northwestern University
Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer	NCT05746325	Anatomic Stage ... Metastatic Brea... Metastatic Mali...	Digital Photogr... Lumbar Puncture Magnetic Resona... Medical Device ...	18 Years -	Mayo Clinic
Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer	NCT05746325	Anatomic Stage ... Metastatic Brea... Metastatic Mali...	Digital Photogr... Lumbar Puncture Magnetic Resona... Medical Device ...	18 Years -	Mayo Clinic
Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers	NCT04460937	Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Distal Esophagu... Gastric Cardia ... Metastatic Esop... Metastatic Esop... Metastatic Gast... Metastatic Mali... Metastatic Mali... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Unresectable Es... Unresectable Es... Unresectable Es... Unresectable Ga...	Adavosertib Radiation Thera...	18 Years -	National Cancer Institute (NCI)
HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases	NCT03696030	Malignant Neopl... Metastatic Mali... Metastatic Mali... Breast Cancer HER2-positive B...	Chimeric Antige...	18 Years - 75 Years	City of Hope Medical Center

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