Spots Global Cancer Trial Database for anatomic stage iv breast cancer ajcc v8

Every month we try and update this database with for anatomic stage iv breast cancer ajcc v8 cancer trials from around the world to help patients and their families find trials that might be right for them.
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Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Fluciclovine and PSMA PET/CT for the Classification and Improved Staging of Invasive Lobular Breast Cancer	NCT04750473	Anatomic Stage ... Invasive Breast... Metastatic Brea... Prognostic Stag...	Computed Tomogr... Fluciclovine F1... Gallium Ga 68 G... Positron Emissi...	18 Years -	Emory University
Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer	NCT02453620	Anatomic Stage ... Anatomic Stage ... Breast Adenocar... Invasive Breast... Malignant Solid...	Biopsy Blood Sample Bone Scan Computed Tomogr... Entinostat Ipilimumab Nivolumab Pharmacogenomic... Pharmacological... Positron Emissi...	18 Years -	National Cancer Institute (NCI)
Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast Cancer	NCT03939897	Anatomic Stage ... Metastatic Brea... Metastatic HER2... Metastatic Horm... Recurrent Breas...	Abemaciclib Biopsy Biospecimen Col... Copanlisib Hydr... Diagnostic Imag... Echocardiograph... Fulvestrant Multigated Acqu...	18 Years -	National Cancer Institute (NCI)
Portable Scalp Cooling System for the Improvement of Chemotherapy-Induced Hair Loss in Patients With Metastatic Breast Cancer	NCT05533320	Anatomic Stage ... Metastatic Brea...	Cold Cap Therap... Quality-of-Life... Questionnaire A...	18 Years -	City of Hope Medical Center
Radiation Therapy and M7824 in Treating Patients With Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer	NCT03524170	Anatomic Stage ... Metastatic Brea... Prognostic Stag...	Bintrafusp Alfa Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases	NCT04752267	Anatomic Stage ... Clinical Stage ... Glioma Malignant Brain... Metastatic Brea... Metastatic Colo... Metastatic Kidn... Metastatic Lung... Metastatic Mali... Metastatic Mela... Pathologic Stag... Prognostic Stag... Stage IV Colon ... Stage IV Lung C... Stage IV Renal ... Stage IVA Colon... Stage IVA Lung ... Stage IVB Colon... Stage IVB Lung ... Stage IVC Colon...	Computed Tomogr... 18F-FMAU Multiparametric... Positron Emissi...	18 Years -	University of Southern California
Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer	NCT02453620	Anatomic Stage ... Anatomic Stage ... Breast Adenocar... Invasive Breast... Malignant Solid...	Biopsy Blood Sample Bone Scan Computed Tomogr... Entinostat Ipilimumab Nivolumab Pharmacogenomic... Pharmacological... Positron Emissi...	18 Years -	National Cancer Institute (NCI)
Cryoablation, Atezolizumab/Nab-paclitaxel for Locally Advanced or Metastatic Triple Negative Breast Cancer	NCT04249167	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Locally Advance... Metastatic Trip... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Atezolizumab Cryosurgery Nab-paclitaxel	18 Years -	Mayo Clinic
Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer	NCT04120246	Anatomic Stage ... HER2 Positive B... Metastatic Brea... Refractory Brea...	Alpha-tocophery... Trastuzumab	18 Years -	Veana Therapeutics
Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Patients With Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial	NCT04704661	Advanced Breast... Advanced Colon ... Advanced Colore... Advanced Endome... Advanced Gastri... Advanced Gastro... Advanced Malign... Advanced Saliva... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... HER2-Positive B... Malignant Hepat... Metastatic Brea... Metastatic Gast... Metastatic Mali... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Stage III Colon... Stage III Color... Stage III Major... Stage III Uteri... Stage IIIA Colo... Stage IIIA Colo... Stage IIIA Uter... Stage IIIB Colo... Stage IIIB Colo... Stage IIIB Uter... Stage IIIC Colo... Stage IIIC Colo... Stage IIIC Uter... Stage IIIC1 Ute... Stage IIIC2 Ute... Stage IV Colon ... Stage IV Colore... Stage IV Major ... Stage IV Uterin... Stage IVA Colon... Stage IVA Color... Stage IVA Major... Stage IVA Uteri... Stage IVB Colon... Stage IVB Color... Stage IVB Major... Stage IVB Uteri... Stage IVC Colon... Stage IVC Color... Stage IVC Major... Unresectable Co... Unresectable Ga... Unresectable Ma...	Ceralasertib Trastuzumab Der...	18 Years -	National Cancer Institute (NCI)
Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer	NCT04639245	Anatomic Stage ... Metastatic Lung... Metastatic Mali... Metastatic Trip... Metastatic Urot... Stage IV Lung C...	Atezolizumab Cyclophosphamid... Fludarabine MAGE-A1-specifi... PD1 Inhibitor	18 Years -	Fred Hutchinson Cancer Center
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer	NCT04491942	Advanced Bile D... Advanced Breast... Advanced Cervic... Advanced Endome... Advanced Esopha... Advanced Gastri... Advanced Head a... Advanced Lung N... Advanced Lung S... Advanced Malign... Advanced Ovaria... Advanced Penile... Advanced Pleura... Advanced Urothe... Anatomic Stage ... Anatomic Stage ... Clinical Stage ... Clinical Stage ... Stage III Cervi... Stage III Dista... Stage III Intra... Stage III Lung ... Stage III Ovari... Stage III Penil... Stage III Pleur... Stage IV Cervic... Stage IV Distal... Stage IV Intrah... Stage IV Lung C... Stage IV Ovaria... Stage IV Penile... Stage IV Pleura... Triple-Negative... Unresectable Ur...	Cisplatin Elimusertib Gemcitabine Hyd...	18 Years -	National Cancer Institute (NCI)
Pembrolizumab and Tamoxifen With or Without Vorinostat for the Treatment of Estrogen Receptor Positive Breast Cancer	NCT04190056	Anatomic Stage ... Prognostic Stag...	Pembrolizumab Tamoxifen Vorinostat	18 Years -	University of California, San Francisco
177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer	NCT04529044	Anatomic Stage ... Metastatic Brea... Prognostic Stag... Recurrent Breas...	Lutetium Lu 177...	18 Years - 100 Years	OHSU Knight Cancer Institute
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery	NCT04588246	Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ...	Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Evaluation of Barriers to Cancer Care Delivery and Outcomes for Women of Color With Metastatic Breast Cancer	NCT06206239	Anatomic Stage ... Metastatic Brea...		18 Years -	Thomas Jefferson University
Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors	NCT04771520	Anatomic Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Metastatic Mali... Metastatic Mela... Metastatic Prim... Metastatic Sarc... Pathologic Stag... Pathologic Stag... Pathologic Stag... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Prognostic Stag... Prognostic Stag... Stage IIIC Colo... Stage IIIC Lung... Stage IV Colore... Stage IV Lung C... Stage IVA Color... Stage IVA Lung ... Stage IVB Color... Stage IVB Lung ... Stage IVC Color...	Avapritinib	18 Years -	M.D. Anderson Cancer Center
Olaparib in Combination With Either Durvalumab, Selumetinib, or Capivasertib or Ceralasertib Alone in Treating Patients With Metastatic Triple Negative Breast Cancer	NCT03801369	Anatomic Stage ... Metastatic Trip...	Biopsy Capivasertib Ceralasertib Durvalumab Olaparib Quality-of-Life... Selumetinib	18 Years -	OHSU Knight Cancer Institute
Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast Cancer	NCT04108858	Anatomic Stage ... HER2-Positive B... Metastatic Brea...	Copanlisib Pertuzumab Trastuzumab	18 Years -	National Cancer Institute (NCI)
Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIV	NCT04514484	Advanced Differ... Advanced Head a... Advanced Hepato... Advanced Kaposi... Advanced Lung N... Advanced Lung S... Advanced Malign... Advanced Melano... Advanced Ovaria... Advanced Prosta... Advanced Renal ... Advanced Thyroi... Advanced Triple... Advanced Urothe... Anatomic Stage ... Anatomic Stage ... Castration-Resi... Clinical Stage ... Clinical Stage ... HIV Infection Metastatic Diff... Metastatic Head... Metastatic Hepa... Metastatic Kapo... Metastatic Lung... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Ovar... Metastatic Pros... Metastatic Rena... Metastatic Thyr... Metastatic Trip... Metastatic Urot... Recurrent Diffe... Recurrent Head ... Recurrent Hepat... Recurrent Kapos... Recurrent Lung ... Recurrent Lung ... Recurrent Malig... Recurrent Melan... Recurrent Ovari... Recurrent Prost... Recurrent Renal... Recurrent Thyro... Recurrent Tripl... Recurrent Uroth... Refractory Diff... Stage III Diffe... Stage III Hepat... Stage III Lung ... Stage III Ovari... Stage III Prost... Stage III Renal... Stage III Thyro... Stage IV Differ... Stage IV Hepato... Stage IV Lung C... Stage IV Ovaria... Stage IV Prosta... Stage IV Renal ... Stage IV Thyroi...	Biospecimen Col... Cabozantinib S-... Computed Tomogr... Magnetic Resona... Nivolumab	18 Years -	National Cancer Institute (NCI)
Estradiol in Treating Patients With ER Beta Positive, Triple Negative Locally Advanced or Metastatic Breast Cancer	NCT03941730	Advanced Triple... Anatomic Stage ... Anatomic Stage ... Metastatic Trip... Recurrent Breas...	Biopsy Computed Tomogr... Magnetic Resona... Positron Emissi... Therapeutic Est...	18 Years -	Mayo Clinic
ZN-c3 for the Treatment of Metastatic Triple-Negative Breast Cancer and Advanced Ovarian Cancer	NCT05368506	Advanced Fallop... Advanced Ovaria... Advanced Primar... Anatomic Stage ... Metastatic Trip... Stage III Fallo... Stage III Ovari... Stage III Prima... Stage IV Fallop... Stage IV Ovaria... Stage IV Primar...	Wee1 Inhibitor ...	18 Years -	OHSU Knight Cancer Institute
Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer	NCT03606967	Anatomic Stage ... Invasive Breast... Metastatic Trip...	Biopsy Biospecimen Col... Carboplatin Computed Tomogr... Durvalumab Gemcitabine Hyd... Magnetic Resona... Nab-paclitaxel Personalized Sy... Poly ICLC Tremelimumab	18 Years -	National Cancer Institute (NCI)
Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer	NCT03774472	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Hydroxychloroqu... Letrozole Palbociclib	18 Years -	M.D. Anderson Cancer Center
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery	NCT04588246	Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ...	Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax	NCT05092373	Advanced Breast... Advanced Endome... Advanced Fallop... Advanced Hepato... Advanced Malign... Advanced Malign... Advanced Malign... Advanced Ovaria... Advanced Primar... Advanced Renal ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Malignant Abdom... Malignant Solid... Metastatic Brea... Metastatic Endo... Metastatic Fall... Metastatic Hepa... Metastatic Mali... Metastatic Mali... Metastatic Mali... Metastatic Ovar... Metastatic Prim... Metastatic Rena... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Stage III Fallo... Stage III Hepat... Stage III Ovari... Stage III Prima... Stage III Renal... Stage III Uteri... Stage IIIA Fall... Stage IIIA Hepa... Stage IIIA Ovar... Stage IIIA Prim... Stage IIIA Uter... Stage IIIA1 Fal... Stage IIIA1 Ova... Stage IIIA2 Fal... Stage IIIA2 Ova... Stage IIIB Fall... Stage IIIB Hepa... Stage IIIB Ovar... Stage IIIB Prim... Stage IIIB Uter... Stage IIIC Fall... Stage IIIC Ovar... Stage IIIC Prim... Stage IIIC Uter... Stage IIIC1 Ute... Stage IIIC2 Ute... Stage IV Fallop... Stage IV Hepato... Stage IV Ovaria... Stage IV Primar... Stage IV Renal ... Stage IV Uterin... Stage IVA Fallo... Stage IVA Hepat... Stage IVA Ovari... Stage IVA Prima... Stage IVA Uteri... Stage IVB Fallo... Stage IVB Hepat... Stage IVB Ovari... Stage IVB Prima... Stage IVB Uteri...	Atezolizumab Cabozantinib S-... Nab-paclitaxel Tumor Treating ...	18 Years -	M.D. Anderson Cancer Center
Testing the Addition of Copanlisib to Eribulin for the Treatment of Advanced-Stage Triple Negative Breast Cancer	NCT04345913	Anatomic Stage ... Anatomic Stage ... Metastatic Trip... Unresectable Tr...	Biopsy Biospecimen Col... Computed Tomogr... Copanlisib Hydr... Eribulin Mesyla... Magnetic Resona...	18 Years -	National Cancer Institute (NCI)
INCMGA00012 and Pelareorep for the Treatment of Metastatic Triple Negative Breast Cancer, IRENE Study	NCT04445844	Anatomic Stage ... Locally Advance... Metastatic Trip... Prognostic Stag... Triple-negative...	Pelareorep Quality-of-Life... Questionnaire A... Retifanlimab	18 Years -	Rutgers, The State University of New Jersey
Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer	NCT05422794	Anatomic Stage ... Anatomic Stage ... Locally Advance... Metastatic Trip... Unresectable Tr...	BET Bromodomain... Biopsy Biospecimen Col... Computed Tomogr... Magnetic Resona... Nab-paclitaxel Pembrolizumab	18 Years -	National Cancer Institute (NCI)
Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.	NCT04305834	Anatomic Stage ... Hormone Recepto... Metastatic Brea... Prognostic Stag...	Abemaciclib Questionnaire A...	70 Years -	City of Hope Medical Center
Lorcaserin in Treating Chemotherapy-Induced Peripheral Neuropathy in Patients With Stage I-IV Gastrointestinal or Breast Cancer	NCT04205071	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Chemotherapy-In... Digestive Syste... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Lorcaserin Lorcaserin Hydr... Questionnaire A...	18 Years -	Ohio State University Comprehensive Cancer Center
INCMGA00012 and Pelareorep for the Treatment of Metastatic Triple Negative Breast Cancer, IRENE Study	NCT04445844	Anatomic Stage ... Locally Advance... Metastatic Trip... Prognostic Stag... Triple-negative...	Pelareorep Quality-of-Life... Questionnaire A... Retifanlimab	18 Years -	Rutgers, The State University of New Jersey
Panitumumab and Pembrolizumab in Combination With Neoadjuvant Chemotherapy for the Treatment of Stage III-IV Triple Negative Breast Cancer	NCT05177796	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Breast Inflamma... Invasive Breast... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Triple-Negative...	Carboplatin Cyclophosphamid... Doxorubicin Paclitaxel Panitumumab Pembrolizumab	18 Years -	M.D. Anderson Cancer Center
An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer	NCT06315296	Anatomic Stage ... Metastatic Brea... Metastatic Lung... Metastatic Mali... Stage IV Lung C...	Behavioral Diet... Text Message-Ba... Internet-Based ... Dietary Counsel... Stereotactic Ra... Biospecimen Col... Magnetic Resona... Neurocognitive ... Questionnaire A... Interview Internet-Based ... Stereotactic Ra... Text Message-Ba... Biospecimen Col... Magnetic Resona... Neurocognitive ... Questionnaire A... Interview	18 Years -	Thomas Jefferson University
Radiation Therapy and M7824 in Treating Patients With Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer	NCT03524170	Anatomic Stage ... Metastatic Brea... Prognostic Stag...	Bintrafusp Alfa Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial	NCT05564377	Advanced Malign... Anatomic Stage ... Anatomic Stage ... Locally Advance... Malignant Femal... Metastatic HER2... Metastatic Mali... Recurrent Endom... Recurrent Fallo... Recurrent Malig... Recurrent Malig... Recurrent Ovari... Recurrent Prima... Unresectable HE... Unresectable Ma...	Alpelisib Binimetinib Biopsy Biospecimen Col... Bone Marrow Asp... Bone Scan Computed Tomogr... Echocardiograph... Fluorouracil Fulvestrant Ipatasertib Leucovorin Magnetic Resona... Multigated Acqu... Mutation Carrie... Neratinib Malea... Nilotinib Hydro... Olaparib Oxaliplatin Paclitaxel Palbociclib Panitumumab Positron Emissi... Selumetinib Sul... Sotorasib	-	National Cancer Institute (NCI)
Mobile Health for Adherence in Breast Cancer Patients	NCT06112613	Anatomic Stage ... Breast Carcinom... HER2-Negative B... Hormone Recepto...	Electronic Heal... Health Promotio... Health Telemoni... Interview Patient Navigat... Survey Administ... Text Message-Ba...	18 Years -	Eastern Cooperative Oncology Group
Testing the Addition of Immunotherapy With Hu5F9-G4 (Magrolimab) to the Usual PARP Inhibitor, Olaparib for Treatment of Metastatic or Recurrent Breast or Castrate-Resistant Prostate Cancer With BRCA Mutations	NCT05807126	Anatomic Stage ... Castration-Resi... Stage IVB Prost...	Biopsy Biospecimen Col... Computed Tomogr... Magnetic Resona... Magrolimab Olaparib	18 Years -	National Cancer Institute (NCI)
Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer	NCT03774472	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Hydroxychloroqu... Letrozole Palbociclib	18 Years -	M.D. Anderson Cancer Center
Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial	NCT04756505	Anatomic Stage ... Hormone Recepto... Metastatic Brea... Metastatic HER2... Prognostic Stag...	Bintrafusp Alfa Immunocytokine ... Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer	NCT06324240	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Early Stage Tri... Locally Advance... Metastatic Trip... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Recurrent Breas... Unresectable Tr...	Ipilimumab Pembrolizumab Vaccine Therapy	18 Years -	Emory University
Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones	NCT04090398	Anatomic Stage ... Metastatic HER2... Metastatic Mali...	Biospecimen Col... Bone Scan Computed Tomogr... Electronic Heal... Magnetic Resona... Paclitaxel Radium Ra 223 D... Single Photon E...	18 Years -	National Cancer Institute (NCI)
Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer	NCT04673448	Anatomic Stage ... Anatomic Stage ... BRCA-Associated... BRCA-Associated... Metastatic BRCA... Metastatic Brea... Metastatic Fall... Metastatic Mali... Metastatic Ovar... Metastatic Panc... Metastatic Prim... Prognostic Stag... Prognostic Stag... Stage III Fallo... Stage III Ovari... Stage III Pancr... Stage III Prima... Stage IV Fallop... Stage IV Ovaria... Stage IV Pancre... Stage IV Primar... Unresectable Br... Unresectable Fa... Unresectable Ma... Unresectable Ov... Unresectable Pa... Unresectable Pr...	Dostarlimab Niraparib	18 Years -	University of Washington
PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery	NCT03218826	Advanced Breast... Advanced Malign... Advanced Prosta... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Castration-Resi... Metastatic Brea... Metastatic Mali... Metastatic Pros... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Stage III Prost... Stage IIIA Pros... Stage IIIB Pros... Stage IIIC Pros... Stage IV Prosta... Stage IVA Prost... Stage IVB Prost... Triple-Negative... Unresectable So...	Docetaxel Laboratory Biom... Pharmacological... PI3Kbeta Inhibi...	18 Years -	National Cancer Institute (NCI)
ZN-c3 for the Treatment of Metastatic Triple-Negative Breast Cancer and Advanced Ovarian Cancer	NCT05368506	Advanced Fallop... Advanced Ovaria... Advanced Primar... Anatomic Stage ... Metastatic Trip... Stage III Fallo... Stage III Ovari... Stage III Prima... Stage IV Fallop... Stage IV Ovaria... Stage IV Primar...	Wee1 Inhibitor ...	18 Years -	OHSU Knight Cancer Institute
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study	NCT03707574	Advanced Malign... Advanced Melano... Advanced Renal ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Stage III Color... Stage III Lung ... Stage III Ovari... Stage III Prost... Stage IIIA Colo... Stage IIIA Lung... Stage IIIA Ovar... Stage IIIA Pros... Stage IIIA1 Ova... Stage IIIA2 Ova... Stage IIIB Colo... Stage IIIB Lung... Stage IIIB Ovar... Stage IIIB Pros... Stage IIIC Colo... Stage IIIC Lung... Stage IIIC Ovar... Stage IIIC Pros... Stage IV Colore... Stage IV Lung C... Stage IV Ovaria... Stage IV Prosta... Stage IVA Color... Stage IVA Lung ... Stage IVA Ovari... Stage IVA Prost... Stage IVB Color... Stage IVB Lung ... Stage IVB Ovari... Stage IVB Prost... Stage IVC Color...	Biospecimen Col...	18 Years -	National Cancer Institute (NCI)
Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer	NCT06179303	Anatomic Stage ... Anatomic Stage ... Locally Advance... Locally Advance... Metastatic HER2... Metastatic Horm...	Abemaciclib Anastrozole Biospecimen Col... Computed Tomogr... Diagnostic Imag... Exemestane Fludeoxyglucose... Fluorine F 18 F... Fulvestrant Gonadotropin-re... Letrozole Positron Emissi... Tamoxifen Therapeutic Est...	18 Years -	University of Washington
Ivermectin and Balstilimab for the Treatment of Metastatic Triple Negative Breast Cancer	NCT05318469	Anatomic Stage ... Metastatic Trip...	Ivermectin Balstilmab	18 Years -	Cedars-Sinai Medical Center
Testing the Addition of Radium Therapy (Radium-223 Dichloride) to the Usual Chemotherapy Treatment (Paclitaxel) for Advanced Breast Cancer That Has Spread to the Bones	NCT04090398	Anatomic Stage ... Metastatic HER2... Metastatic Mali...	Biospecimen Col... Bone Scan Computed Tomogr... Electronic Heal... Magnetic Resona... Paclitaxel Radium Ra 223 D... Single Photon E...	18 Years -	National Cancer Institute (NCI)
Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer	NCT03774472	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Hydroxychloroqu... Letrozole Palbociclib	18 Years -	M.D. Anderson Cancer Center
Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer	NCT05746325	Anatomic Stage ... Metastatic Brea... Metastatic Mali...	Digital Photogr... Lumbar Puncture Magnetic Resona... Medical Device ...	18 Years -	Mayo Clinic
Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer	NCT05756166	Anatomic Stage ... Metastatic Trip... Unresectable Tr...	Biopsy Biospecimen Col... Celecoxib Computed Tomogr... Interferon Alph... Magnetic Resona... Pembrolizumab Rintatolimod	18 Years -	Roswell Park Cancer Institute
T-DM1 With or Without Abemaciclib for the Treatment of HER2-Positive Metastatic Breast Cancer	NCT04351230	Anatomic Stage ... HER2 Positive B... Metastatic Brea... Prognostic Stag...	Abemaciclib Trastuzumab Emt...	18 Years -	Academic and Community Cancer Research United
Effects of Ribociclib and Palbociclib on Tumor and Blood Characteristics in Patients With Metastatic Breast Cancer	NCT05244434	Advanced Breast... Advanced HER2-N... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Hormone Recepto... Metastatic Brea... Metastatic HER2... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Best Practice Biopsy Biospecimen Col... Laboratory Biom...	18 Years -	City of Hope Medical Center
Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer	NCT02849496	Anatomic Stage ... Anatomic Stage ... Locally Advance... Locally Advance... Metastatic Brea... Metastatic HER2... Unresectable Br... Unresectable HE...	Atezolizumab Biopsy Biospecimen Col... Bone Marrow Asp... Bone Marrow Bio... Bone Scan Computed Tomogr... Magnetic Resona... Olaparib Positron Emissi... Questionnaire A... X-Ray Imaging	18 Years -	National Cancer Institute (NCI)
Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer	NCT03606967	Anatomic Stage ... Invasive Breast... Metastatic Trip...	Biopsy Biospecimen Col... Carboplatin Computed Tomogr... Durvalumab Gemcitabine Hyd... Magnetic Resona... Nab-paclitaxel Personalized Sy... Poly ICLC Tremelimumab	18 Years -	National Cancer Institute (NCI)
National Cancer Institute "Cancer Moonshot Biobank"	NCT04314401	Acute Myeloid L... Anatomic Stage ... Anatomic Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Lung Non-Small ... Lung Small Cell... Malignant Solid... Metastatic Pros... Multiple Myelom... Stage III Lung ... Stage III Ovari... Stage IV Colore... Stage IV Lung C... Stage IV Ovaria... Stage IV Prosta... Stage IVB Prost...	Biospecimen Col... Medical Chart R...	13 Years -	National Cancer Institute (NCI)
Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial)	NCT05554354	Anatomic Stage ... Metastatic HER2... Metastatic Horm...	Binimetinib Biopsy Biospecimen Col... Bone Scan Computed Tomogr... Echocardiograph... Fulvestrant Magnetic Resona... Multigated Acqu...	18 Years -	National Cancer Institute (NCI)
Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)	NCT05751668	Anatomic Stage ... Chemotherapy-In... Metastatic Brea...	Paclitaxel Monosialotetrah... Questionnaire A... Quality-of-life... Placebo Adminis...	18 Years -	Alliance for Clinical Trials in Oncology
National Cancer Institute "Cancer Moonshot Biobank"	NCT04314401	Acute Myeloid L... Anatomic Stage ... Anatomic Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Lung Non-Small ... Lung Small Cell... Malignant Solid... Metastatic Pros... Multiple Myelom... Stage III Lung ... Stage III Ovari... Stage IV Colore... Stage IV Lung C... Stage IV Ovaria... Stage IV Prosta... Stage IVB Prost...	Biospecimen Col... Medical Chart R...	13 Years -	National Cancer Institute (NCI)
Optimizing Treatment of Stage IV Breast Cancer Through Real-Time Disease Monitoring	NCT04906369	Anatomic Stage ... Metastatic Brea... Prognostic Stag...	Biospecimen Col...	18 Years -	Mayo Clinic
Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast Cancer	NCT04108858	Anatomic Stage ... HER2-Positive B... Metastatic Brea...	Copanlisib Pertuzumab Trastuzumab	18 Years -	National Cancer Institute (NCI)
Topical or Oral Minoxidil for the Treatment of Endocrine Therapy-Induced Alopecia in Patients With Stage I-IV Breast Cancer	NCT05417308	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Endocrine Thera... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Minoxidil Minoxidil Quality-of-Life... Questionnaire A...	18 Years -	Ohio State University Comprehensive Cancer Center
Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the Body	NCT05198843	Anatomic Stage ... Metastatic Trip...	Dasatinib Icosapent Ethyl	18 Years -	National Cancer Institute (NCI)
Ketoconazole Before Surgery in Treating Patients With Recurrent Glioma or Breast Cancer Brain Metastases	NCT03796273	Anatomic Stage ... Astrocytoma Breast Carcinom... Glioma Invasive Breast... Oligodendroglio... Prognostic Stag... Recurrent Gliom...	Best Practice Ketoconazole	18 Years -	Wake Forest University Health Sciences
Olaparib in Combination With Either Durvalumab, Selumetinib, or Capivasertib or Ceralasertib Alone in Treating Patients With Metastatic Triple Negative Breast Cancer	NCT03801369	Anatomic Stage ... Metastatic Trip...	Biopsy Capivasertib Ceralasertib Durvalumab Olaparib Quality-of-Life... Selumetinib	18 Years -	OHSU Knight Cancer Institute
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases	NCT04752267	Anatomic Stage ... Clinical Stage ... Glioma Malignant Brain... Metastatic Brea... Metastatic Colo... Metastatic Kidn... Metastatic Lung... Metastatic Mali... Metastatic Mela... Pathologic Stag... Prognostic Stag... Stage IV Colon ... Stage IV Lung C... Stage IV Renal ... Stage IVA Colon... Stage IVA Lung ... Stage IVB Colon... Stage IVB Lung ... Stage IVC Colon...	Computed Tomogr... 18F-FMAU Multiparametric... Positron Emissi...	18 Years -	University of Southern California
Dendritic Cell-Based Treatment Plus Immunotherapy for the Treatment of Metastatic or Unresectable Triple Negative Breast Cancer	NCT05539365	Anatomic Stage ... Anatomic Stage ... Metastatic Trip... Unresectable Tr...	Alpha-type-1 Po... Biopsy Computed Tomogr... Leukapheresis Pembrolizumab Quality-of-Life...	18 Years -	Roswell Park Cancer Institute
Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel	NCT04862585	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Breast Carcinom... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Cimetidine Dexamethasone Diphenhydramine Famotidine Paclitaxel Quality-of-Life... Ranitidine	18 Years -	Ohio State University Comprehensive Cancer Center
Breast Cancer Vaccine in Combination With Pembrolizumab for Treatment of Persistent, Recurrent, or Metastatic Breast Cancer	NCT04418219	Anatomic Stage ... Metastatic Brea... Prognostic Stag... Recurrent Breas... Refractory Brea...	Cyclophosphamid... Allogeneic GM-C... Pembrolizumab Recombinant Int... Questionnaire A... Quality of Life...	18 Years -	Thomas Jefferson University
Testing an Omega-3 Fatty Acid-Based Anti-Cancer Therapy for Patients With Triple-Negative Inflammatory Breast Cancer That Has Spread to Other Parts of the Body	NCT05198843	Anatomic Stage ... Metastatic Trip...	Dasatinib Icosapent Ethyl	18 Years -	National Cancer Institute (NCI)
TVB-2640 and Trastuzumab With Paclitaxel or Endocrine Therapy for Treatment of HER2 Positive Metastatic Breast Cancer	NCT03179904	Advanced Breast... HER2-Positive B... Anatomic Stage ... Anatomic Stage ... HER2-positive B...	Anastrozole Denifanstat Exemestane Fulvestrant Echocardiograph... Letrozole Paclitaxel Trastuzumab Computed Tomogr... Magnetic Resona... Biospecimen Col... Biopsy	18 Years -	Mayo Clinic
A Study of a New Drug Combination, Copanlisib and Fulvestrant, in Advanced Breast Cancer	NCT03803761	Anatomic Stage ... Metastatic Brea... Metastatic Mali... Prognostic Stag...	Copanlisib Fulvestrant	18 Years -	National Cancer Institute (NCI)
Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel	NCT04862585	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Breast Carcinom... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Cimetidine Dexamethasone Diphenhydramine Famotidine Paclitaxel Quality-of-Life... Ranitidine	18 Years -	Ohio State University Comprehensive Cancer Center
Letrozole and Imatinib Mesylate in Treating Postmenopausal Participants With Estrogen or Progesterone Positive Metastatic Breast Cancer	NCT00338728	Anatomic Stage ... Estrogen Recept... KIT Positive PDGFR Positive Postmenopausal Progesterone Re... Prognostic Stag...	Imatinib Mesyla... Letrozole	-	M.D. Anderson Cancer Center
In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors	NCT04616248	Anatomic Stage ... Metastatic Brea... Prognostic Stag... Unresectable Br... Metastatic Mela... Unresectable Me... Cutaneous Squam... Merkel Cell Car... Soft Tissue Sar... Bone Sarcoma Sarcoma,Soft Ti... Sarcoma of Bone	Anti-CD40 Agoni... Poly ICLC Radiation Thera... Recombinant Flt...	18 Years -	University of Southern California
Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer	NCT05746325	Anatomic Stage ... Metastatic Brea... Metastatic Mali...	Digital Photogr... Lumbar Puncture Magnetic Resona... Medical Device ...	18 Years -	Mayo Clinic
Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial	NCT04756505	Anatomic Stage ... Hormone Recepto... Metastatic Brea... Metastatic HER2... Prognostic Stag...	Bintrafusp Alfa Immunocytokine ... Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Genetic Testing in Predicting Tumor Response in Patients With Stage I-III HER2 Negative Invasive Breast Cancer	NCT01334021	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Invasive Breast... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag...	Biopsy Conventional Su... Genetic Testing	18 Years -	M.D. Anderson Cancer Center
Panitumumab and Pembrolizumab in Combination With Neoadjuvant Chemotherapy for the Treatment of Stage III-IV Triple Negative Breast Cancer	NCT05177796	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Breast Inflamma... Invasive Breast... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Triple-Negative...	Carboplatin Cyclophosphamid... Doxorubicin Paclitaxel Panitumumab Pembrolizumab	18 Years -	M.D. Anderson Cancer Center

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