Spots Global Cancer Trial Database for metastatic breast carcinoma

Every month we try and update this database with for metastatic breast carcinoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast Cancer	NCT03939897	Anatomic Stage ... Metastatic Brea... Metastatic HER2... Metastatic Horm... Recurrent Breas...	Abemaciclib Biopsy Biospecimen Col... Copanlisib Hydr... Diagnostic Imag... Echocardiograph... Fulvestrant Multigated Acqu...	18 Years -	National Cancer Institute (NCI)
Portable Scalp Cooling System for the Improvement of Chemotherapy-Induced Hair Loss in Patients With Metastatic Breast Cancer	NCT05533320	Anatomic Stage ... Metastatic Brea...	Cold Cap Therap... Quality-of-Life... Questionnaire A...	18 Years -	City of Hope Medical Center
Radiation Therapy and M7824 in Treating Patients With Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer	NCT03524170	Anatomic Stage ... Metastatic Brea... Prognostic Stag...	Bintrafusp Alfa Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Feasibility of Integrating the Outcomes4Me Smartphone Navigation Application Into the Care Management of Breast Cancer Patients	NCT04262518	Breast Cancer Invasive Breast... Metastatic Brea... Breast Carcinom... Metastatic Brea...	Outcomes4Me Mob...	18 Years -	Outcomes4Me
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors	NCT04541225	Glioma Glioma, Maligna... Glioma, Mixed Glial Cell Tumo... Breast Cancer Breast Carcinom... Cancer of Breas... Cancer of the B... Breast Tumor Malignant Tumor... Advanced Breast... Advanced Breast... Metastatic Brea... Metastatic Brea... Prostate Cancer Prostatic Cance... Cancer of Prost... Cancer of the P... Prostate Neopla... Castrate Resist... Castration-resi... Castration Resi... Glioblastoma Recurrent Gliob...	NUV-422	18 Years -	Nuvation Bio Inc.
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases	NCT04752267	Anatomic Stage ... Clinical Stage ... Glioma Malignant Brain... Metastatic Brea... Metastatic Colo... Metastatic Kidn... Metastatic Lung... Metastatic Mali... Metastatic Mela... Pathologic Stag... Prognostic Stag... Stage IV Colon ... Stage IV Lung C... Stage IV Renal ... Stage IVA Colon... Stage IVA Lung ... Stage IVB Colon... Stage IVB Lung ... Stage IVC Colon...	Computed Tomogr... 18F-FMAU Multiparametric... Positron Emissi...	18 Years -	University of Southern California
Onalespib and Paclitaxel in Treating Patients With Advanced Triple Negative Breast Cancer	NCT02474173	Advanced Breast... Metastatic Brea... Stage III Breas... Stage IIIA Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast... Triple-Negative...	Laboratory Biom... Onalespib Paclitaxel Pharmacological...	18 Years -	National Cancer Institute (NCI)
Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer	NCT04120246	Anatomic Stage ... HER2 Positive B... Metastatic Brea... Refractory Brea...	Alpha-tocophery... Trastuzumab	18 Years -	Veana Therapeutics
Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Patients With Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial	NCT04704661	Advanced Breast... Advanced Colon ... Advanced Colore... Advanced Endome... Advanced Gastri... Advanced Gastro... Advanced Malign... Advanced Saliva... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... HER2-Positive B... Malignant Hepat... Metastatic Brea... Metastatic Gast... Metastatic Mali... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Stage III Colon... Stage III Color... Stage III Major... Stage III Uteri... Stage IIIA Colo... Stage IIIA Colo... Stage IIIA Uter... Stage IIIB Colo... Stage IIIB Colo... Stage IIIB Uter... Stage IIIC Colo... Stage IIIC Colo... Stage IIIC Uter... Stage IIIC1 Ute... Stage IIIC2 Ute... Stage IV Colon ... Stage IV Colore... Stage IV Major ... Stage IV Uterin... Stage IVA Colon... Stage IVA Color... Stage IVA Major... Stage IVA Uteri... Stage IVB Colon... Stage IVB Color... Stage IVB Major... Stage IVB Uteri... Stage IVC Colon... Stage IVC Color... Stage IVC Major... Unresectable Co... Unresectable Ga... Unresectable Ma...	Ceralasertib Trastuzumab Der...	18 Years -	National Cancer Institute (NCI)
Repeatability of 68-GaNOTA-Anti-HER2 VHH1 PET/CT in Breast Carcinoma Patients	NCT03924466	Metastatic Brea... Locally Advance... Cancer of Pancr... Solid Tumor Wit... Salivary Gland ... Gastric Cancer Endometrial Can... Uterine Cancer Non Small Cell ... Biliary Tract C... Cholangiocarcin... Colorectal Canc... Urothelial Carc... Prostate Cancer	68GaNOTA-Anti-H...	18 Years -	Universitair Ziekenhuis Brussel
Fulvestrant With or Without Bortezomib in Patients With Inoperable Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer	NCT01142401	Metastatic Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast...	Bortezomib Fulvestrant Laboratory Biom...	18 Years -	National Cancer Institute (NCI)
177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer	NCT04529044	Anatomic Stage ... Metastatic Brea... Prognostic Stag... Recurrent Breas...	Lutetium Lu 177...	18 Years - 100 Years	OHSU Knight Cancer Institute
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery	NCT04588246	Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ...	Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Evaluation of Barriers to Cancer Care Delivery and Outcomes for Women of Color With Metastatic Breast Cancer	NCT06206239	Anatomic Stage ... Metastatic Brea...		18 Years -	Thomas Jefferson University
Repeatability of 68-GaNOTA-Anti-HER2 VHH1 PET/CT in Breast Carcinoma Patients	NCT03924466	Metastatic Brea... Locally Advance... Cancer of Pancr... Solid Tumor Wit... Salivary Gland ... Gastric Cancer Endometrial Can... Uterine Cancer Non Small Cell ... Biliary Tract C... Cholangiocarcin... Colorectal Canc... Urothelial Carc... Prostate Cancer	68GaNOTA-Anti-H...	18 Years -	Universitair Ziekenhuis Brussel
Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast Cancer	NCT04108858	Anatomic Stage ... HER2-Positive B... Metastatic Brea...	Copanlisib Pertuzumab Trastuzumab	18 Years -	National Cancer Institute (NCI)
The p53 Breast Cancer Trial	NCT02965950	Locally Advance... Metastatic Brea...	Cyclophosphamid...	18 Years -	Haukeland University Hospital
The p53 Breast Cancer Trial	NCT02965950	Locally Advance... Metastatic Brea...	Cyclophosphamid...	18 Years -	Haukeland University Hospital
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery	NCT04588246	Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ...	Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax	NCT05092373	Advanced Breast... Advanced Endome... Advanced Fallop... Advanced Hepato... Advanced Malign... Advanced Malign... Advanced Malign... Advanced Ovaria... Advanced Primar... Advanced Renal ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Malignant Abdom... Malignant Solid... Metastatic Brea... Metastatic Endo... Metastatic Fall... Metastatic Hepa... Metastatic Mali... Metastatic Mali... Metastatic Mali... Metastatic Ovar... Metastatic Prim... Metastatic Rena... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Stage III Fallo... Stage III Hepat... Stage III Ovari... Stage III Prima... Stage III Renal... Stage III Uteri... Stage IIIA Fall... Stage IIIA Hepa... Stage IIIA Ovar... Stage IIIA Prim... Stage IIIA Uter... Stage IIIA1 Fal... Stage IIIA1 Ova... Stage IIIA2 Fal... Stage IIIA2 Ova... Stage IIIB Fall... Stage IIIB Hepa... Stage IIIB Ovar... Stage IIIB Prim... Stage IIIB Uter... Stage IIIC Fall... Stage IIIC Ovar... Stage IIIC Prim... Stage IIIC Uter... Stage IIIC1 Ute... Stage IIIC2 Ute... Stage IV Fallop... Stage IV Hepato... Stage IV Ovaria... Stage IV Primar... Stage IV Renal ... Stage IV Uterin... Stage IVA Fallo... Stage IVA Hepat... Stage IVA Ovari... Stage IVA Prima... Stage IVA Uteri... Stage IVB Fallo... Stage IVB Hepat... Stage IVB Ovari... Stage IVB Prima... Stage IVB Uteri...	Atezolizumab Cabozantinib S-... Nab-paclitaxel Tumor Treating ...	18 Years -	M.D. Anderson Cancer Center
Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.	NCT04305834	Anatomic Stage ... Hormone Recepto... Metastatic Brea... Prognostic Stag...	Abemaciclib Questionnaire A...	70 Years -	City of Hope Medical Center
An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer	NCT06315296	Anatomic Stage ... Metastatic Brea... Metastatic Lung... Metastatic Mali... Stage IV Lung C...	Behavioral Diet... Text Message-Ba... Internet-Based ... Dietary Counsel... Stereotactic Ra... Biospecimen Col... Magnetic Resona... Neurocognitive ... Questionnaire A... Interview Internet-Based ... Stereotactic Ra... Text Message-Ba... Biospecimen Col... Magnetic Resona... Neurocognitive ... Questionnaire A... Interview	18 Years -	Thomas Jefferson University
Radiation Therapy and M7824 in Treating Patients With Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer	NCT03524170	Anatomic Stage ... Metastatic Brea... Prognostic Stag...	Bintrafusp Alfa Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Nab-Paclitaxel in Treating Older Patients With Locally Advanced or Metastatic Breast Cancer	NCT01463072	Locally Advance... Metastatic Brea... Recurrent Breas... Stage III Breas... Stage IIIA Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast...	Laboratory Biom... Nab-paclitaxel Questionnaire A...	65 Years -	City of Hope Medical Center
Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial	NCT04756505	Anatomic Stage ... Hormone Recepto... Metastatic Brea... Metastatic HER2... Prognostic Stag...	Bintrafusp Alfa Immunocytokine ... Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer	NCT04673448	Anatomic Stage ... Anatomic Stage ... BRCA-Associated... BRCA-Associated... Metastatic BRCA... Metastatic Brea... Metastatic Fall... Metastatic Mali... Metastatic Ovar... Metastatic Panc... Metastatic Prim... Prognostic Stag... Prognostic Stag... Stage III Fallo... Stage III Ovari... Stage III Pancr... Stage III Prima... Stage IV Fallop... Stage IV Ovaria... Stage IV Pancre... Stage IV Primar... Unresectable Br... Unresectable Fa... Unresectable Ma... Unresectable Ov... Unresectable Pa... Unresectable Pr...	Dostarlimab Niraparib	18 Years -	University of Washington
Metastatic Breast Carcinoma and Women Sexual Quality of Life	NCT03408769	Metastatic Brea...	Medical questio...	50 Years - 70 Years	Institut de Cancérologie de Lorraine
PI3Kbeta Inhibitor AZD8186 and Docetaxel in Treating Patients Advanced Solid Tumors With PTEN or PIK3CB Mutations That Are Metastatic or Cannot Be Removed by Surgery	NCT03218826	Advanced Breast... Advanced Malign... Advanced Prosta... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Castration-Resi... Metastatic Brea... Metastatic Mali... Metastatic Pros... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Stage III Prost... Stage IIIA Pros... Stage IIIB Pros... Stage IIIC Pros... Stage IV Prosta... Stage IVA Prost... Stage IVB Prost... Triple-Negative... Unresectable So...	Docetaxel Laboratory Biom... Pharmacological... PI3Kbeta Inhibi...	18 Years -	National Cancer Institute (NCI)
Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer	NCT05746325	Anatomic Stage ... Metastatic Brea... Metastatic Mali...	Digital Photogr... Lumbar Puncture Magnetic Resona... Medical Device ...	18 Years -	Mayo Clinic
Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases	NCT02595905	Metastatic BRCA... Metastatic Brea... Metastatic Mali... Metastatic Trip... Recurrent Breas... Stage IV Breast...	Cisplatin Laboratory Biom... Placebo Adminis... Veliparib	18 Years -	National Cancer Institute (NCI)
Feasibility of Integrating the Outcomes4Me Smartphone Navigation Application Into the Care Management of Breast Cancer Patients	NCT04262518	Breast Cancer Invasive Breast... Metastatic Brea... Breast Carcinom... Metastatic Brea...	Outcomes4Me Mob...	18 Years -	Outcomes4Me
T-DM1 With or Without Abemaciclib for the Treatment of HER2-Positive Metastatic Breast Cancer	NCT04351230	Anatomic Stage ... HER2 Positive B... Metastatic Brea... Prognostic Stag...	Abemaciclib Trastuzumab Emt...	18 Years -	Academic and Community Cancer Research United
Testing Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast Cancer	NCT02849496	Anatomic Stage ... Anatomic Stage ... Locally Advance... Locally Advance... Metastatic Brea... Metastatic HER2... Unresectable Br... Unresectable HE...	Atezolizumab Biopsy Biospecimen Col... Bone Marrow Asp... Bone Marrow Bio... Bone Scan Computed Tomogr... Magnetic Resona... Olaparib Positron Emissi... Questionnaire A... X-Ray Imaging	18 Years -	National Cancer Institute (NCI)
Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)	NCT05751668	Anatomic Stage ... Chemotherapy-In... Metastatic Brea...	Paclitaxel Monosialotetrah... Questionnaire A... Quality-of-life... Placebo Adminis...	18 Years -	Alliance for Clinical Trials in Oncology
Apollo Device for Metastatic Breast Cancer (MBC)	NCT04983342	Fatigue Metastatic Brea...	Apollo Armband	18 Years - 100 Years	University of Pittsburgh
Purged Circulating Tumor Cells (CTCs) From Metastatic Breast Cancer	NCT00429182	Breast Cancer Metastatic Brea... Invasive Breast...	Carboplatin Cyclophosphamid... Thiotepa Stem Cell Trans...	18 Years - 55 Years	M.D. Anderson Cancer Center
Optimizing Treatment of Stage IV Breast Cancer Through Real-Time Disease Monitoring	NCT04906369	Anatomic Stage ... Metastatic Brea... Prognostic Stag...	Biospecimen Col...	18 Years -	Mayo Clinic
Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast Cancer	NCT04108858	Anatomic Stage ... HER2-Positive B... Metastatic Brea...	Copanlisib Pertuzumab Trastuzumab	18 Years -	National Cancer Institute (NCI)
A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer	NCT05534438	Oligometastatic... Breast Cancer Metastatic Brea... Metastatic Brea... ER+ Breast Canc... HER2+ Breast Ca...	Stereotactic bo...	18 Years -	Memorial Sloan Kettering Cancer Center
Pembrolizumab, Endocrine Therapy, and Palbociclib in Treating Postmenopausal Patients With Newly Diagnosed Metastatic Stage IV Estrogen Receptor Positive Breast Cancer	NCT02778685	Metastatic Brea... Stage IV Breast...	Fulvestrant Laboratory Biom... Letrozole Palbociclib Pembrolizumab	18 Years -	City of Hope Medical Center
Cyclophosphamide and Veliparib in Treating Patients With Locally Advanced or Metastatic Breast Cancer	NCT01351909	Locally Advance... Metastatic Brea... Recurrent Breas... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast...	Cyclophosphamid... Laboratory Biom... Veliparib	18 Years -	National Cancer Institute (NCI)
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors	NCT04541225	Glioma Glioma, Maligna... Glioma, Mixed Glial Cell Tumo... Breast Cancer Breast Carcinom... Cancer of Breas... Cancer of the B... Breast Tumor Malignant Tumor... Advanced Breast... Advanced Breast... Metastatic Brea... Metastatic Brea... Prostate Cancer Prostatic Cance... Cancer of Prost... Cancer of the P... Prostate Neopla... Castrate Resist... Castration-resi... Castration Resi... Glioblastoma Recurrent Gliob...	NUV-422	18 Years -	Nuvation Bio Inc.
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases	NCT04752267	Anatomic Stage ... Clinical Stage ... Glioma Malignant Brain... Metastatic Brea... Metastatic Colo... Metastatic Kidn... Metastatic Lung... Metastatic Mali... Metastatic Mela... Pathologic Stag... Prognostic Stag... Stage IV Colon ... Stage IV Lung C... Stage IV Renal ... Stage IVA Colon... Stage IVA Lung ... Stage IVB Colon... Stage IVB Lung ... Stage IVC Colon...	Computed Tomogr... 18F-FMAU Multiparametric... Positron Emissi...	18 Years -	University of Southern California
Breast Cancer Vaccine in Combination With Pembrolizumab for Treatment of Persistent, Recurrent, or Metastatic Breast Cancer	NCT04418219	Anatomic Stage ... Metastatic Brea... Prognostic Stag... Recurrent Breas... Refractory Brea...	Cyclophosphamid... Allogeneic GM-C... Pembrolizumab Recombinant Int... Questionnaire A... Quality of Life...	18 Years -	Thomas Jefferson University
A Study of a New Drug Combination, Copanlisib and Fulvestrant, in Advanced Breast Cancer	NCT03803761	Anatomic Stage ... Metastatic Brea... Metastatic Mali... Prognostic Stag...	Copanlisib Fulvestrant	18 Years -	National Cancer Institute (NCI)
In Situ Immunomodulation With CDX-301, Radiation Therapy, CDX-1140 and Poly-ICLC in Patients w/ Unresectable and Metastatic Solid Tumors	NCT04616248	Anatomic Stage ... Metastatic Brea... Prognostic Stag... Unresectable Br... Metastatic Mela... Unresectable Me... Cutaneous Squam... Merkel Cell Car... Soft Tissue Sar... Bone Sarcoma Sarcoma,Soft Ti... Sarcoma of Bone	Anti-CD40 Agoni... Poly ICLC Radiation Thera... Recombinant Flt...	18 Years -	University of Southern California
Tumor Treating Fields for the Treatment of Leptomeningeal Metastases of the Spine in Patients With Breast Cancer	NCT05746325	Anatomic Stage ... Metastatic Brea... Metastatic Mali...	Digital Photogr... Lumbar Puncture Magnetic Resona... Medical Device ...	18 Years -	Mayo Clinic
Immunotherapy (NHS-IL12 & Bintrafusp Alfa) and Radiation Therapy for the Treatment of Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer, the REINA Trial	NCT04756505	Anatomic Stage ... Hormone Recepto... Metastatic Brea... Metastatic HER2... Prognostic Stag...	Bintrafusp Alfa Immunocytokine ... Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Fulvestrant With or Without Bortezomib in Patients With Inoperable Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer	NCT01142401	Metastatic Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast...	Bortezomib Fulvestrant Laboratory Biom...	18 Years -	National Cancer Institute (NCI)
Breast Cancer Pathways Program Impact on Patient Shared Decision Making and Experience in Academic and Community Practice	NCT04297384	Anatomic Stage ... Breast Carcinom... Metastatic Brea... Prognostic Stag... Recurrent Breas...	Informational I... Informational I... Quality-of-Life... Survey Administ...	18 Years -	Roswell Park Cancer Institute
Nab-Paclitaxel in Treating Older Patients With Locally Advanced or Metastatic Breast Cancer	NCT01463072	Locally Advance... Metastatic Brea... Recurrent Breas... Stage III Breas... Stage IIIA Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast...	Laboratory Biom... Nab-paclitaxel Questionnaire A...	65 Years -	City of Hope Medical Center
Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer	NCT04120246	Anatomic Stage ... HER2 Positive B... Metastatic Brea... Refractory Brea...	Alpha-tocophery... Trastuzumab	18 Years -	Veana Therapeutics
A Video Intervention to Improve Patient Understanding of Tumor Genomic Testing in Patients With Metastatic Cancer	NCT05215769	Anatomic Stage ... Metastatic Brea... Metastatic Lung... Metastatic Mali... Prognostic Stag... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Health Educatio... Questionnaire A...	18 Years -	Ohio State University Comprehensive Cancer Center
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery	NCT04588246	Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ...	Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer	NCT03101748	Breast Inflamma... Locally Advance... Metastatic Brea... Stage III Breas... Stage IIIA Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast...	Cyclophosphamid... Doxorubicin Laboratory Biom... Neratinib Paclitaxel Pertuzumab Trastuzumab	18 Years -	M.D. Anderson Cancer Center
Radioembolization of Metastatic Breast Cancer to the Liver as a 2nd/3rd Line Therapy	NCT05315687	Anatomic Stage ... Metastatic Brea... Metastatic Carc... Prognostic Stag...	Y-90 SIR-Sphere... Yttrium-90 Micr... Systemic Therap...	18 Years -	Emory University
An Interactive Time-Restricted Diet Intervention (txt4fasting) for Reducing Neurocognitive Decline and Improving Survival in Patients With Brain Metastases From Breast or Lung Cancer	NCT06315296	Anatomic Stage ... Metastatic Brea... Metastatic Lung... Metastatic Mali... Stage IV Lung C...	Behavioral Diet... Text Message-Ba... Internet-Based ... Dietary Counsel... Stereotactic Ra... Biospecimen Col... Magnetic Resona... Neurocognitive ... Questionnaire A... Interview Internet-Based ... Stereotactic Ra... Text Message-Ba... Biospecimen Col... Magnetic Resona... Neurocognitive ... Questionnaire A... Interview	18 Years -	Thomas Jefferson University
Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations	NCT04550494	Advanced Pancre... Anatomic Stage ... Anatomic Stage ... Castration-Resi... Clinical Stage ... Clinical Stage ... HER2-Positive B... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Metastatic Brea... Metastatic Gast... Metastatic Mali... Metastatic Ovar... Metastatic Panc... Metastatic Pros... Platinum-Sensit... Stage II Pancre... Stage III Ovari... Stage III Pancr... Stage III Prost... Stage IV Ovaria... Stage IV Pancre... Stage IV Prosta...	Biopsy Biospecimen Col... Computed Tomogr... Magnetic Resona... Talazoparib	18 Years -	National Cancer Institute (NCI)
Abexinostat, Palbociclib, and Fulvestrant for the Treatment of Breast or Gynecologic Cancer	NCT04498520	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Hormone Recepto... Locally Advance... Metastatic Brea... Metastatic Endo... Metastatic Fall... Metastatic HER2... Metastatic Mali... Metastatic Ovar... Metastatic Prim... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Recurrent Fallo... Recurrent Ovari... Recurrent Prima... Refractory Brea... Stage IV Fallop... Stage IV Ovaria... Stage IV Primar... Stage IV Uterin... Stage IVA Fallo... Stage IVA Ovari... Stage IVA Prima... Stage IVA Uteri... Stage IVB Fallo... Stage IVB Ovari... Stage IVB Prima... Stage IVB Uteri...	Abexinostat Tos... Fulvestrant Palbociclib	18 Years -	University of California, San Francisco
Optimizing Treatment of Stage IV Breast Cancer Through Real-Time Disease Monitoring	NCT04906369	Anatomic Stage ... Metastatic Brea... Prognostic Stag...	Biospecimen Col...	18 Years -	Mayo Clinic
A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer	NCT05534438	Oligometastatic... Breast Cancer Metastatic Brea... Metastatic Brea... ER+ Breast Canc... HER2+ Breast Ca...	Stereotactic bo...	18 Years -	Memorial Sloan Kettering Cancer Center
The p53 Breast Cancer Trial	NCT02965950	Locally Advance... Metastatic Brea...	Cyclophosphamid...	18 Years -	Haukeland University Hospital
Veliparib With or Without Carboplatin in Treating Patients With Stage III or IV Breast Cancer	NCT01149083	Anatomic Stage ... Anatomic Stage ... Locally Advance... Metastatic Brea... Unresectable Br...	Biopsy Biospecimen Col... Carboplatin Computed Tomogr... Magnetic Resona... Veliparib	18 Years -	National Cancer Institute (NCI)
Clinical Information and Biospecimen Collection From Patients With Recurrent or Stage IV Breast Cancer	NCT03737695	Anatomic Stage ... Invasive Breast... Metastatic Brea... Peritoneal Effu... Recurrent Breas...	Biospecimen Col... Medical Chart R...	18 Years -	Mayo Clinic
An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis	NCT05376878	Anatomic Stage ... Metastatic Brea... Metastatic Mali...	Copper Cu 64-DO... Magnetic Resona... Positron Emissi... Trastuzumab Trastuzumab Der...	18 Years -	City of Hope Medical Center
Clinical Information and Biospecimen Collection From Patients With Recurrent or Stage IV Breast Cancer	NCT03737695	Anatomic Stage ... Invasive Breast... Metastatic Brea... Peritoneal Effu... Recurrent Breas...	Biospecimen Col... Medical Chart R...	18 Years -	Mayo Clinic
Fulvestrant With or Without Bortezomib in Patients With Inoperable Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer	NCT01142401	Metastatic Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast...	Bortezomib Fulvestrant Laboratory Biom...	18 Years -	National Cancer Institute (NCI)
Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival	NCT02364557	Anatomic Stage ... Metastatic Brea... Metastatic Mali... Metastatic Mali... Metastatic Mali... Metastatic Mali... Metastatic Mali... Prognostic Stag... Anatomic Stage ...	Stereotactic Bo... Surgery	18 Years -	NRG Oncology
Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study	NCT04316117	Anatomic Stage ... Hormone Recepto... Metastatic Brea... Prognostic Stag...	Computed Tomogr... Fludeoxyglucose... Positron Emissi...	18 Years -	Eastern Cooperative Oncology Group
Abexinostat, Palbociclib, and Fulvestrant for the Treatment of Breast or Gynecologic Cancer	NCT04498520	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Hormone Recepto... Locally Advance... Metastatic Brea... Metastatic Endo... Metastatic Fall... Metastatic HER2... Metastatic Mali... Metastatic Ovar... Metastatic Prim... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Recurrent Fallo... Recurrent Ovari... Recurrent Prima... Refractory Brea... Stage IV Fallop... Stage IV Ovaria... Stage IV Primar... Stage IV Uterin... Stage IVA Fallo... Stage IVA Ovari... Stage IVA Prima... Stage IVA Uteri... Stage IVB Fallo... Stage IVB Ovari... Stage IVB Prima... Stage IVB Uteri...	Abexinostat Tos... Fulvestrant Palbociclib	18 Years -	University of California, San Francisco
Alpha-TEA and Trastuzumab for the Treatment of Refractory HER2+ Metastatic Breast Cancer	NCT04120246	Anatomic Stage ... HER2 Positive B... Metastatic Brea... Refractory Brea...	Alpha-tocophery... Trastuzumab	18 Years -	Veana Therapeutics
Nab-Paclitaxel in Treating Older Patients With Locally Advanced or Metastatic Breast Cancer	NCT01463072	Locally Advance... Metastatic Brea... Recurrent Breas... Stage III Breas... Stage IIIA Brea... Stage IIIB Brea... Stage IIIC Brea... Stage IV Breast...	Laboratory Biom... Nab-paclitaxel Questionnaire A...	65 Years -	City of Hope Medical Center
177Lu-DOTATATE for the Treatment of Stage IV or Recurrent Breast Cancer	NCT04529044	Anatomic Stage ... Metastatic Brea... Prognostic Stag... Recurrent Breas...	Lutetium Lu 177...	18 Years - 100 Years	OHSU Knight Cancer Institute
A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer	NCT05534438	Oligometastatic... Breast Cancer Metastatic Brea... Metastatic Brea... ER+ Breast Canc... HER2+ Breast Ca...	Stereotactic bo...	18 Years -	Memorial Sloan Kettering Cancer Center

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