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Spots Global Cancer Trial Database for berzosertib

Every month we try and update this database with for berzosertib cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)NCT04768296
Small-cell Lung...
Berzosertib
Berzosertib
Topotecan
18 Years - EMD Serono
Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube CancerNCT02627443
Metastatic Fall...
Metastatic Ovar...
Metastatic Prim...
Ovarian Endomet...
Ovarian High Gr...
Platinum-Sensit...
Recurrent Fallo...
Recurrent Ovari...
Recurrent Prima...
Stage IV Fallop...
Stage IV Ovaria...
Stage IV Primar...
Berzosertib
Carboplatin
Gemcitabine Hyd...
Laboratory Biom...
Pharmacological...
18 Years - National Cancer Institute (NCI)
Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck CancerNCT02567422
Head and Neck C...
Head and Neck S...
Stage III Hypop...
Stage III Laryn...
Stage III Oral ...
Stage III Oroph...
Stage III Sinon...
Stage IV Hypoph...
Stage IV Laryng...
Stage IV Oral C...
Stage IV Oropha...
Stage IV Sinona...
Berzosertib
Cisplatin
Computed Tomogr...
Laboratory Biom...
Magnetic Resona...
Positron Emissi...
Radiation Thera...
18 Years - National Cancer Institute (NCI)
Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube CancerNCT02627443
Metastatic Fall...
Metastatic Ovar...
Metastatic Prim...
Ovarian Endomet...
Ovarian High Gr...
Platinum-Sensit...
Recurrent Fallo...
Recurrent Ovari...
Recurrent Prima...
Stage IV Fallop...
Stage IV Ovaria...
Stage IV Primar...
Berzosertib
Carboplatin
Gemcitabine Hyd...
Laboratory Biom...
Pharmacological...
18 Years - National Cancer Institute (NCI)
Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine TumorsNCT02589522
Metastatic Lung...
Metastatic Lung...
Metastatic Lung...
Metastatic Mali...
Stage IV Lung C...
Stage IVA Lung ...
Stage IVB Lung ...
Berzosertib
Quality-of-Life...
Therapeutic Con...
Whole-Brain Rad...
18 Years - National Cancer Institute (NCI)
Gemcitabine Hydrochloride Alone or With M6620 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube CancerNCT02595892
Ovarian Serous ...
Recurrent Fallo...
Recurrent Ovari...
Recurrent Prima...
Berzosertib
Gemcitabine
Gemcitabine Hyd...
18 Years - National Cancer Institute (NCI)
Cisplatin and Gemcitabine Hydrochloride With or Without Berzosertib in Treating Patients With Metastatic Urothelial CancerNCT02567409
Metastatic Blad...
Metastatic Rena...
Metastatic Uret...
Stage IV Bladde...
Berzosertib
Cisplatin
Gemcitabine Hyd...
18 Years - National Cancer Institute (NCI)
Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the LungsNCT03896503
Bladder Small C...
Extensive Stage...
Extrapulmonary ...
Limited Stage L...
Platinum-Resist...
Platinum-Sensit...
Prostate Small ...
Recurrent Lung ...
Berzosertib
Biopsy
Biospecimen Col...
Computed Tomogr...
Topotecan Hydro...
18 Years - National Cancer Institute (NCI)
Gemcitabine Hydrochloride Alone or With M6620 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube CancerNCT02595892
Ovarian Serous ...
Recurrent Fallo...
Recurrent Ovari...
Recurrent Prima...
Berzosertib
Gemcitabine
Gemcitabine Hyd...
18 Years - National Cancer Institute (NCI)
Berzosertib and Irinotecan in Treating Patients With Progressive, Metastatic, or Unresectable TP53 Mutant Gastric or Gastroesophageal Junction CancerNCT03641313
Clinical Stage ...
Clinical Stage ...
Clinical Stage ...
Clinical Stage ...
Metastatic Gast...
Metastatic Gast...
Unresectable Ga...
Unresectable Ga...
Berzosertib
Computed Tomogr...
Endoscopic Biop...
Irinotecan
Magnetic Resona...
18 Years - National Cancer Institute (NCI)
Randomized Trial of Topotecan With M6620, an ATR Kinase Inhibitor, in Small Cell Lung Cancers and Small Cell Cancers Outside of the LungsNCT03896503
Bladder Small C...
Extensive Stage...
Extrapulmonary ...
Limited Stage L...
Platinum-Resist...
Platinum-Sensit...
Prostate Small ...
Recurrent Lung ...
Berzosertib
Biopsy
Biospecimen Col...
Computed Tomogr...
Topotecan Hydro...
18 Years - National Cancer Institute (NCI)
Berzosertib + Topotecan in Relapsed Platinum-Resistant Small-Cell Lung Cancer (DDRiver SCLC 250)NCT04768296
Small-cell Lung...
Berzosertib
Berzosertib
Topotecan
18 Years - EMD Serono
Berzosertib Human Mass Balance Study (DDRiver Solid Tumors 208)NCT05246111
Advanced Solid ...
[14C]M6620
M6620
Topotecan
18 Years - Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid TumorsNCT04266912
Metastatic Mali...
Refractory Mali...
Unresectable Ma...
Avelumab
Berzosertib
18 Years - M.D. Anderson Cancer Center
M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryNCT02595931
Metastatic Colo...
Metastatic Lung...
Metastatic Mali...
Metastatic Panc...
Refractory Colo...
Refractory Lung...
Refractory Mali...
Refractory Panc...
Stage III Color...
Stage III Lung ...
Stage III Pancr...
Stage IV Colore...
Stage IV Lung C...
Stage IV Pancre...
Unresectable Co...
Unresectable Lu...
Unresectable Ma...
Unresectable Pa...
Berzosertib
Biopsy Specimen
Biospecimen Col...
Computed Tomogr...
Irinotecan Hydr...
18 Years - National Cancer Institute (NCI)
Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck CancerNCT02567422
Head and Neck C...
Head and Neck S...
Stage III Hypop...
Stage III Laryn...
Stage III Oral ...
Stage III Oroph...
Stage III Sinon...
Stage IV Hypoph...
Stage IV Laryng...
Stage IV Oral C...
Stage IV Oropha...
Stage IV Sinona...
Berzosertib
Cisplatin
Computed Tomogr...
Laboratory Biom...
Magnetic Resona...
Positron Emissi...
Radiation Thera...
18 Years - National Cancer Institute (NCI)
M6620 and Carboplatin With or Without Docetaxel in Treating Patients With Metastatic Castration-Resistant Prostate CancerNCT03517969
Castration-Resi...
Metastatic Pros...
Stage IV Prosta...
Berzosertib
Carboplatin
Docetaxel
Laboratory Biom...
18 Years - National Cancer Institute (NCI)
Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine TumorsNCT02589522
Metastatic Lung...
Metastatic Lung...
Metastatic Lung...
Metastatic Mali...
Stage IV Lung C...
Stage IVA Lung ...
Stage IVB Lung ...
Berzosertib
Quality-of-Life...
Therapeutic Con...
Whole-Brain Rad...
18 Years - National Cancer Institute (NCI)
Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine TumorsNCT02589522
Metastatic Lung...
Metastatic Lung...
Metastatic Lung...
Metastatic Mali...
Stage IV Lung C...
Stage IVA Lung ...
Stage IVB Lung ...
Berzosertib
Quality-of-Life...
Therapeutic Con...
Whole-Brain Rad...
18 Years - National Cancer Institute (NCI)
Testing the Addition of M6620 (VX-970, Berzosertib) to Usual Chemotherapy and Radiation for Head and Neck CancerNCT02567422
Head and Neck C...
Head and Neck S...
Stage III Hypop...
Stage III Laryn...
Stage III Oral ...
Stage III Oroph...
Stage III Sinon...
Stage IV Hypoph...
Stage IV Laryng...
Stage IV Oral C...
Stage IV Oropha...
Stage IV Sinona...
Berzosertib
Cisplatin
Computed Tomogr...
Laboratory Biom...
Magnetic Resona...
Positron Emissi...
Radiation Thera...
18 Years - National Cancer Institute (NCI)
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