Spots Global Cancer Trial Database for stage iv pancreatic cancer ajcc v8

Every month we try and update this database with for stage iv pancreatic cancer ajcc v8 cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer	NCT03816358	Pancreatic Aden... Stage II Pancre... Stage III Pancr... Stage IV Pancre...	Anetumab Ravtan... Biopsy Biospecimen Col... Gemcitabine Hyd... Ipilimumab Nivolumab	18 Years -	National Cancer Institute (NCI)
Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer	NCT05911243	Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Stage II Pancre... Stage III Pancr... Stage IV Pancre...	Acupressure The... Best Practice Biospecimen Col... Questionnaire A...	18 Years - 65 Years	University of Washington
Testing the Addition of Pembrolizumab, an Immunotherapy Cancer Drug to Olaparib Alone as Therapy for Patients With Pancreatic Cancer That Has Spread With Inherited BRCA Mutations	NCT04548752	Metastatic Panc... Pancreatic Aden... Stage IV Pancre...	Biopsy Biospecimen Col... Computed Tomogr... Magnetic Resona... Olaparib Pembrolizumab	18 Years -	National Cancer Institute (NCI)
Binimetinib and Hydroxychloroquine in Treating Patients With KRAS Mutant Metastatic Pancreatic Cancer	NCT04132505	Metastatic Panc... Stage IV Pancre...	Binimetinib Hydroxychloroqu...	18 Years -	M.D. Anderson Cancer Center
SD-101, Nivolumab, and Radiation Therapy in Treating Patients With Chemotherapy-Refractory Metastatic Pancreatic Cancer	NCT04050085	Metastatic Panc... Refractory Panc... Stage IV Pancre...	Nivolumab Radiation Thera... TLR9 Agonist SD...	18 Years -	University of California, Davis
Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer	NCT04887805	Advanced Pancre... Stage II Pancre... Stage IIA Pancr... Stage IIB Pancr... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Lenvatinib Mesy... Pembrolizumab	18 Years -	City of Hope Medical Center
Gemcitabine, Nab-Paclitaxel, and Bosentan for the Treatment of Unresectable Pancreatic Cancer	NCT04158635	Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Bosentan Gemcitabine Nab-paclitaxel Quality-of-Life... Questionnaire A...	18 Years -	City of Hope Medical Center
Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer	NCT06381154	Locally Advance... Metastatic Panc... Stage II Pancre... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Biopsy Biospecimen Col... Computed Tomogr... Endoscopic Ultr... Fluorouracil Irinotecan Leucovorin Lymph Node Biop... Magnetic Resona... Oxaliplatin Pembrolizumab Photodynamic Th... Positron Emissi... Questionnaire A... Verteporfin	18 Years -	Mayo Clinic
Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread	NCT04233866	Metastatic Panc... Stage IV Pancre...	Fluorouracil Gemcitabine Gemcitabine Hyd... Leucovorin Leucovorin Calc... Liposomal Irino... Nab-paclitaxel Quality-of-Life... Questionnaire A...	70 Years -	Eastern Cooperative Oncology Group
Testing the Combination of Anetumab Ravtansine With Either Nivolumab, Nivolumab and Ipilimumab, or Gemcitabine and Nivolumab in Advanced Pancreatic Cancer	NCT03816358	Pancreatic Aden... Stage II Pancre... Stage III Pancr... Stage IV Pancre...	Anetumab Ravtan... Biopsy Biospecimen Col... Gemcitabine Hyd... Ipilimumab Nivolumab	18 Years -	National Cancer Institute (NCI)
Pembrolizumab and PEGPH20 in Treating Patients With Metastatic Pancreatic Cancer	NCT04058964	Metastatic Panc... Stage IV Pancre...	Pegylated Recom... Pembrolizumab	18 Years -	M.D. Anderson Cancer Center
Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors and Lymphomas	NCT05053971	Advanced Lympho... Advanced Malign... Advanced Pancre... B-Cell Non-Hodg... Metastatic Panc... Refractory B-Ce... Refractory Lymp... Refractory Mali... Refractory Panc... Refractory T-Ce... Stage II Pancre... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	BET Bromodomain... Core Biopsy Entinostat	18 Years -	National Cancer Institute (NCI)
Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer	NCT02983578	Advanced Colore... Advanced Lung N... Lung Non-Small ... Mismatch Repair... Refractory Colo... Refractory Lung... Refractory Panc... Stage II Pancre... Stage III Color... Stage III Lung ... Stage III Pancr... Stage IIIA Colo... Stage IIIA Lung... Stage IIIB Colo... Stage IIIB Lung... Stage IIIC Colo... Stage IIIC Lung... Stage IV Colore... Stage IV Lung C... Stage IV Pancre... Stage IVA Color... Stage IVA Lung ... Stage IVB Color... Stage IVB Lung ... Stage IVC Color...	Danvatirsen Durvalumab	18 Years -	M.D. Anderson Cancer Center
Enhanced Outpatient Symptom Management to Reduce Acute Care Visits Due to Chemotherapy-Related Adverse Events	NCT05038254	Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Metastatic Colo... Metastatic Esop... Metastatic Gast... Metastatic Live... Metastatic Mali... Metastatic Mali... Metastatic Mali... Metastatic Panc... Metastatic Rect... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Stage IV Colon ... Stage IV Hepato... Stage IV Pancre... Stage IV Rectal... Stage IV Small ... Stage IVA Colon... Stage IVA Hepat... Stage IVA Recta... Stage IVB Colon... Stage IVB Hepat... Stage IVB Recta... Stage IVC Colon... Stage IVC Recta...	Best Practice Patient Monitor... Questionnaire A...	18 Years -	M.D. Anderson Cancer Center
Pembrolizumab and Pelareorep in Treating Patients With Advanced Pancreatic Cancer	NCT03723915	Pancreatic Aden... Stage III Pancr... Stage IV Pancre...	Pembrolizumab Wild-type Reovi...	18 Years -	Northwestern University
Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas	NCT03925428	Advanced Lympho... Advanced Malign... Ann Arbor Stage... Ann Arbor Stage... Ann Arbor Stage... Ann Arbor Stage... Refractory B-Ce... Refractory Lymp... Refractory Mali... Refractory Panc... Refractory T-Ce... Stage II Pancre... Stage IIA Pancr... Stage IIB Pancr... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Entinostat Molibresib	12 Years -	National Cancer Institute (NCI)
Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial	NCT05554367	Malignant Solid... Ovarian Low Gra... Pancreatic Carc... Stage IV Ovaria... Stage IV Pancre...	Binimetinib Biopsy Biospecimen Col... Bone Scan Computed Tomogr... Magnetic Resona... Palbociclib	18 Years -	National Cancer Institute (NCI)
Niraparib and TSR-042 for the Treatment of BRCA-Mutated Unresectable or Metastatic Breast, Pancreas, Ovary, Fallopian Tube, or Primary Peritoneal Cancer	NCT04673448	Anatomic Stage ... Anatomic Stage ... BRCA-Associated... BRCA-Associated... Metastatic BRCA... Metastatic Brea... Metastatic Fall... Metastatic Mali... Metastatic Ovar... Metastatic Panc... Metastatic Prim... Prognostic Stag... Prognostic Stag... Stage III Fallo... Stage III Ovari... Stage III Pancr... Stage III Prima... Stage IV Fallop... Stage IV Ovaria... Stage IV Pancre... Stage IV Primar... Unresectable Br... Unresectable Fa... Unresectable Ma... Unresectable Ov... Unresectable Pa... Unresectable Pr...	Dostarlimab Niraparib	18 Years -	University of Washington
FL118 for Treating Patients With Advanced Pancreatic Ductal Adenocarcinoma	NCT06206876	Advanced Pancre... Locally Advance... Metastatic Panc... Refractory Panc... Stage II Pancre... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Biopsy Biospecimen Col... Computed Tomogr... DDX5 Degrader F... Magnetic Resona...	18 Years -	Roswell Park Cancer Institute
Niraparib and Dostarlimab for the Treatment of Germline or Somatic BRCA1/2 and PALB2 Mutated Metastatic Pancreatic Cancer	NCT04493060	Metastatic Panc... Stage IV Pancre...	Dostarlimab Niraparib	18 Years -	Mayo Clinic
Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Pancreatic, Colorectal and Non-Small Cell Lung Cancers With KRAS G12V Mutations	NCT06043713	Metastatic Colo... Metastatic Lung... Metastatic Panc... Stage IV Colore... Stage IV Lung C... Stage IV Pancre...	Bendamustine Biopsy Biospecimen Col... Computed Tomogr... Cyclophosphamid... Echocardiograph... Fludarabine Leukapheresis Magnetic Resona... Multigated Acqu... Positron Emissi... T-cell Receptor...	18 Years -	Fred Hutchinson Cancer Center
Binimetinib and Encorafenib for the Treatment of Pancreatic Cancer in Patients With a Somatic BRAF V600E Mutation	NCT04390243	Locally Advance... Metastatic Panc... Recurrent Pancr... Stage III Pancr... Stage IV Pancre...	Binimetinib Encorafenib	18 Years -	Academic and Community Cancer Research United
Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma	NCT06398587	Locally Advance... Metastatic Panc... Stage II Pancre... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Onvansertib Gemcitabine Nab-paclitaxel Electrocardiogr... Magnetic Resona... Positron Emissi... Biospecimen Col... Biospecimen Col... Computed Tomogr...	18 Years -	OHSU Knight Cancer Institute
Disulfiram and Chemotherapy in Treating Patients With Refractory Solid Tumors or Metastatic Pancreatic Cancer	NCT02671890	Metastatic Panc... Refractory Mali... Stage IV Pancre...	Chemotherapy Disulfiram Gemcitabine Hyd... Laboratory Biom...	18 Years -	Mayo Clinic
Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer	NCT04821284	Locally Advance... Metastatic Panc... Stage II Pancre... Stage IIA Pancr... Stage IIB Pancr... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Gemcitabine Hyd... Nab-paclitaxel Fluorouracil Irinotecan Hydr... Leucovorin Calc... Oxaliplatin Perflubutane Mi... Contrast-Enhanc... Quality-of-Life... Computed Tomogr... Magnetic Resona...	18 Years -	Thomas Jefferson University
Feasibility of Auricular Acupressure for Appetite and Weight in Patients With Stage II-IV Gastric, Esophageal, and Pancreatic Cancer	NCT05911243	Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Stage II Pancre... Stage III Pancr... Stage IV Pancre...	Acupressure The... Best Practice Biospecimen Col... Questionnaire A...	18 Years - 65 Years	University of Washington
Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer	NCT01585805	Locally Advance... Metastatic Panc... Stage III Pancr... Stage IV Pancre...	Biopsy Biospecimen Col... Cisplatin Computed Tomogr... Gemcitabine Gemcitabine Hyd... Magnetic Resona... Veliparib	18 Years -	National Cancer Institute (NCI)
Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors	NCT04616534	Advanced Fallop... Advanced Malign... Advanced Ovaria... Advanced Pancre... Advanced Primar... Fallopian Tube ... Metastatic Panc... Ovarian High Gr... Platinum-Resist... Platinum-Resist... Platinum-Resist... Primary Periton... Stage II Pancre... Stage III Fallo... Stage III Ovari... Stage III Pancr... Stage III Prima... Stage IV Fallop... Stage IV Ovaria... Stage IV Pancre... Stage IV Primar... Unresectable Pa...	Biopsy Biospecimen Col... Diagnostic Imag... Elimusertib Gemcitabine	18 Years -	National Cancer Institute (NCI)
CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors	NCT05733000	Advanced Biliar... Advanced Colore... Advanced Gastro... Advanced Lung A... Advanced Malign... Advanced Ovaria... Advanced Pancre... Advanced Urothe... Clinical Stage ... Clinical Stage ... Metastatic Bili... Metastatic Colo... Metastatic Gast... Metastatic Lung... Metastatic Ovar... Metastatic Panc... Metastatic Urot... Refractory Bili... Refractory Colo... Refractory Gast... Refractory Lung... Refractory Ovar... Refractory Panc... Refractory Urot... Stage II Pancre... Stage III Color... Stage III Lung ... Stage III Ovari... Stage III Pancr... Stage IV Colore... Stage IV Lung C... Stage IV Ovaria... Stage IV Pancre...	Biospecimen Col... Computed Tomogr... Devimistat Fluorouracil Gemcitabine Hyd... Hydroxychloroqu... Magnetic Resona...	18 Years -	Northwestern University
Siltuximab and Spartalizumab in Patients With Metastatic Pancreatic Cancer	NCT04191421	Metastatic Panc... Stage IV Pancre...	Siltuximab Spartalizumab	18 Years -	Emory University
Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma	NCT04809766	Metastatic Panc... Stage IV Pancre...	Autologous Meso... Cyclophosphamid... Fludarabine Bendamustine	18 Years -	Fred Hutchinson Cancer Center
Disulfiram and Chemotherapy in Treating Patients With Refractory Solid Tumors or Metastatic Pancreatic Cancer	NCT02671890	Metastatic Panc... Refractory Mali... Stage IV Pancre...	Chemotherapy Disulfiram Gemcitabine Hyd... Laboratory Biom...	18 Years -	Mayo Clinic
A Phase I Study of SOR-C13 in Patients With Advanced Solid Tumors	NCT03784677	Advanced Malign... Refractory Mali... Refractory Ovar... Refractory Panc... Stage II Pancre... Stage IIA Pancr... Stage IIB Pancr... Stage III Ovari... Stage III Pancr... Stage III Prost... Stage IIIA Ovar... Stage IIIA Pros... Stage IIIB Ovar... Stage IIIB Pros... Stage IIIC Ovar... Stage IIIC Pros... Stage IV Ovaria... Stage IV Pancre... Stage IV Prosta... Stage IVA Ovari... Stage IVA Prost... Stage IVB Ovari... Stage IVB Prost...	TRPV6 Calcium C...	18 Years -	M.D. Anderson Cancer Center
Real-Time Monitoring of Chemotherapy Side-Effects in Patients With Gastrointestinal Cancers, RT-CAMSS Study	NCT04449679	Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Stage 0 Colorec... Stage 0 Pancrea... Stage I Colorec... Stage I Pancrea... Stage IA Pancre... Stage IB Pancre... Stage II Colore... Stage II Pancre... Stage IIA Color... Stage IIA Pancr... Stage IIB Color... Stage IIB Pancr... Stage IIC Color... Stage III Color... Stage III Pancr... Stage IIIA Colo... Stage IIIB Colo... Stage IIIC Colo... Stage IV Colore... Stage IV Pancre... Stage IVA Color... Stage IVB Color... Stage IVC Color...	Patient Monitor... Questionnaire A... Consultation	18 Years -	Thomas Jefferson University
Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors	NCT04616534	Advanced Fallop... Advanced Malign... Advanced Ovaria... Advanced Pancre... Advanced Primar... Fallopian Tube ... Metastatic Panc... Ovarian High Gr... Platinum-Resist... Platinum-Resist... Platinum-Resist... Primary Periton... Stage II Pancre... Stage III Fallo... Stage III Ovari... Stage III Pancr... Stage III Prima... Stage IV Fallop... Stage IV Ovaria... Stage IV Pancre... Stage IV Primar... Unresectable Pa...	Biopsy Biospecimen Col... Diagnostic Imag... Elimusertib Gemcitabine	18 Years -	National Cancer Institute (NCI)
Hyperthermic Intraperitoneal Chemotherapy for the Treatment of Pancreatic Cancer and Peritoneal Metastasis	NCT04858009	Metastatic Panc... Stage IV Pancre... Metastatic Mali...	Cisplatin Hyperthermic In... Nab-paclitaxel Computed Tomogr... Magnetic Resona... Positron Emissi...	18 Years - 80 Years	Mayo Clinic
Gemcitabine Hydrochloride and Cisplatin With or Without Veliparib or Veliparib Alone in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer	NCT01585805	Locally Advance... Metastatic Panc... Stage III Pancr... Stage IV Pancre...	Biopsy Biospecimen Col... Cisplatin Computed Tomogr... Gemcitabine Gemcitabine Hyd... Magnetic Resona... Veliparib	18 Years -	National Cancer Institute (NCI)
Binimetinib and Hydroxychloroquine in Treating Patients With KRAS Mutant Metastatic Pancreatic Cancer	NCT04132505	Metastatic Panc... Stage IV Pancre...	Binimetinib Hydroxychloroqu...	18 Years -	M.D. Anderson Cancer Center
Palbociclib and Binimetinib in RAS-Mutant Cancers, A ComboMATCH Treatment Trial	NCT05554367	Malignant Solid... Ovarian Low Gra... Pancreatic Carc... Stage IV Ovaria... Stage IV Pancre...	Binimetinib Biopsy Biospecimen Col... Bone Scan Computed Tomogr... Magnetic Resona... Palbociclib	18 Years -	National Cancer Institute (NCI)
Lenvatinib and Pembrolizumab Maintenance Therapy for the Treatment of Patients of Advanced Unresectable Pancreatic Cancer	NCT04887805	Advanced Pancre... Stage II Pancre... Stage IIA Pancr... Stage IIB Pancr... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Lenvatinib Mesy... Pembrolizumab	18 Years -	City of Hope Medical Center
Calaspargase Pegol-Mnkl and Cobimetinib for the Treatment of Locally Advanced or Metastatic Pancreatic Cancer	NCT05034627	Locally Advance... Metastatic Panc... Stage II Pancre... Stage IIA Pancr... Stage IIB Pancr... Stage III Pancr... Stage IV Pancre...	Biopsy Calaspargase Pe... Cobimetinib	18 Years -	OHSU Knight Cancer Institute
NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer	NCT04539808	Pancreatic Aden... Stage 0 Pancrea... Stage I Pancrea... Stage III Pancr... Stage IV Pancre...	Capecitabine Fluorouracil Irinotecan Hydr... Leucovorin Calc... Losartan Potass... Oxaliplatin Radiation Thera... Resection Diagnostic Imag... Biospecimen Col...	18 Years -	OHSU Knight Cancer Institute
Epacadostat and Pembrolizumab in Treating Participants With Advanced Pancreatic Cancer	NCT03432676	ATM Gene Mutati... Deleterious BRC... Deleterious BRC... Homologous Reco... Pancreatic Duct... Stage II Pancre... Stage IIA Pancr... Stage IIB Pancr... Stage III Pancr... Stage IV Pancre...	Epacadostat Pembrolizumab	18 Years -	M.D. Anderson Cancer Center
Sonoporation and Chemotherapy for the Treatment of Pancreatic Cancer	NCT04821284	Locally Advance... Metastatic Panc... Stage II Pancre... Stage IIA Pancr... Stage IIB Pancr... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Gemcitabine Hyd... Nab-paclitaxel Fluorouracil Irinotecan Hydr... Leucovorin Calc... Oxaliplatin Perflubutane Mi... Contrast-Enhanc... Quality-of-Life... Computed Tomogr... Magnetic Resona...	18 Years -	Thomas Jefferson University
Testing the Addition of an Anti-cancer Drug, Elimusertib (BAY 1895344) ATR Inhibitor, to the Chemotherapy Treatment (Gemcitabine) for Advanced Pancreatic and Ovarian Cancer, and Advanced Solid Tumors	NCT04616534	Advanced Fallop... Advanced Malign... Advanced Ovaria... Advanced Pancre... Advanced Primar... Fallopian Tube ... Metastatic Panc... Ovarian High Gr... Platinum-Resist... Platinum-Resist... Platinum-Resist... Primary Periton... Stage II Pancre... Stage III Fallo... Stage III Ovari... Stage III Pancr... Stage III Prima... Stage IV Fallop... Stage IV Ovaria... Stage IV Pancre... Stage IV Primar... Unresectable Pa...	Biopsy Biospecimen Col... Diagnostic Imag... Elimusertib Gemcitabine	18 Years -	National Cancer Institute (NCI)
CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma	NCT04387071	Locally Advance... Metastatic Panc... Stage IV Pancre... Unresectable Ma...	Agonistic Anti-... VLP-encapsulate...	18 Years -	University of Southern California
iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation	NCT03608631	KRAS NP_004976.... Metastatic Panc... Pancreatic Duct... Stage IV Pancre...	Mesenchymal Str...	18 Years -	M.D. Anderson Cancer Center
Paricalcitol and Hydroxychloroquine in Combination With Gemcitabine and Nab-Paclitaxel for Advanced Pancreatic Cancer	NCT04524702	Advanced Pancre... Metastatic Panc... Stage IV Pancre...	Gemcitabine Hydroxychloroqu... Nab-paclitaxel Paricalcitol	18 Years -	Emory University
CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer	NCT05685602	Metastatic Panc... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Biopsy Biospecimen Col... Computed Tomogr... Emavusertib Gemcitabine Hyd... Magnetic Resona... Nab-paclitaxel Positron Emissi... X-Ray Imaging	18 Years -	National Cancer Institute (NCI)
Pharmacogenomics Testing in Directing the Optimal Use of Supportive Care Medications in Patients With Stage III-IV Cancer	NCT04067960	Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Biliary Tract C... Clinical Stage ... Clinical Stage ... Malignant Brain... Malignant Genit... Malignant Solid... Pancreatobiliar... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Stage III Color... Stage III Ovari... Stage III Pancr... Stage III Prost... Stage IIIA Colo... Stage IIIA Ovar... Stage IIIA Pros... Stage IIIB Colo... Stage IIIB Ovar... Stage IIIB Pros... Stage IIIC Colo... Stage IIIC Ovar... Stage IIIC Pros... Stage IV Colore... Stage IV Ovaria... Stage IV Pancre... Stage IV Prosta... Stage IVA Color... Stage IVA Ovari... Stage IVA Pancr... Stage IVA Prost... Stage IVB Color... Stage IVB Ovari... Stage IVB Pancr... Stage IVB Prost... Stage IVC Color...	Biospecimen Col... Genetic Testing Quality-of-Life... Questionnaire A...	-	Mayo Clinic
CMP-001 and INCAGN01949 for Patients With Stage IV Pancreatic Cancer and Other Cancers Except Melanoma	NCT04387071	Locally Advance... Metastatic Panc... Stage IV Pancre... Unresectable Ma...	Agonistic Anti-... VLP-encapsulate...	18 Years -	University of Southern California
Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread	NCT04233866	Metastatic Panc... Stage IV Pancre...	Fluorouracil Gemcitabine Gemcitabine Hyd... Leucovorin Leucovorin Calc... Liposomal Irino... Nab-paclitaxel Quality-of-Life... Questionnaire A...	70 Years -	Eastern Cooperative Oncology Group
Targeted Pathway Inhibition in Patients With Pancreatic Cancer	NCT04005690	Locally Advance... Metastatic Panc... Stage II Pancre... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Cobimetinib Olaparib Onvansertib Azenosertib	18 Years -	OHSU Knight Cancer Institute
The PLATINUM Trial: Optimizing Chemotherapy for the Second-Line Treatment of Metastatic BRCA1/2 or PALB2-Associated Metastatic Pancreatic Cancer	NCT06115499	Pancreatic Acin... Pancreatic Aden... Pancreatic Aden... Pancreatic Carc... Pancreatic Duct... Pancreatic Squa... Stage IV Pancre...	Nab paclitaxel Gemcitabine Cisplatin Magnetic Resona... Computed Tomogr... Biospecimen Col...	18 Years -	Alliance for Clinical Trials in Oncology
Photoradiation With Verteporfin to Facilitate Immunologic Activity of Pembrolizumab in Unresectable, Locally Advance or Metastatic Pancreatic Cancer	NCT06381154	Locally Advance... Metastatic Panc... Stage II Pancre... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Biopsy Biospecimen Col... Computed Tomogr... Endoscopic Ultr... Fluorouracil Irinotecan Leucovorin Lymph Node Biop... Magnetic Resona... Oxaliplatin Pembrolizumab Photodynamic Th... Positron Emissi... Questionnaire A... Verteporfin	18 Years -	Mayo Clinic
M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery	NCT02595931	Metastatic Colo... Metastatic Lung... Metastatic Mali... Metastatic Panc... Refractory Colo... Refractory Lung... Refractory Mali... Refractory Panc... Stage III Color... Stage III Lung ... Stage III Pancr... Stage IV Colore... Stage IV Lung C... Stage IV Pancre... Unresectable Co... Unresectable Lu... Unresectable Ma... Unresectable Pa...	Berzosertib Biopsy Specimen Biospecimen Col... Computed Tomogr... Irinotecan Hydr...	18 Years -	National Cancer Institute (NCI)
Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations	NCT04550494	Advanced Pancre... Anatomic Stage ... Anatomic Stage ... Castration-Resi... Clinical Stage ... Clinical Stage ... HER2-Positive B... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Metastatic Brea... Metastatic Gast... Metastatic Mali... Metastatic Ovar... Metastatic Panc... Metastatic Pros... Platinum-Sensit... Stage II Pancre... Stage III Ovari... Stage III Pancr... Stage III Prost... Stage IV Ovaria... Stage IV Pancre... Stage IV Prosta...	Biopsy Biospecimen Col... Computed Tomogr... Magnetic Resona... Talazoparib	18 Years -	National Cancer Institute (NCI)
SMMART Adaptive Clinical Treatment (ACT) Trial	NCT05238831	Advanced Breast... Advanced Malign... Advanced Ovaria... Advanced Pancre... Advanced Prosta... Advanced Sarcom... Anatomic Stage ... Anatomic Stage ... Recurrent Adult... Recurrent Breas... Recurrent Ovari... Recurrent Prost... Stage II Pancre... Stage III Ovari... Stage III Pancr... Stage IV Ovaria... Stage IV Pancre...	Alectinib Alpelisib Anastrozole Atezolizumab Bevacizumab Biopsy Biospecimen Col... Capecitabine Carboplatin Cobimetinib Entrectinib Eribulin Fulvestrant Hyaluronidase-z... Irinotecan Letrozole Nab-paclitaxel Niraparib Olaparib Paclitaxel Palbociclib Pertuzumab Quality-of-Life... Trastuzumab Trastuzumab Emt... Vemurafenib Vinorelbine Vismodegib	18 Years -	OHSU Knight Cancer Institute
Ultrasound-Guided Verteporfin Photodynamic Therapy for the Treatment of Unresectable Solid Pancreatic Tumors or Advanced Pancreatic Cancer, VERTPAC-02 Study	NCT03033225	Advanced Pancre... Locally Advance... Metastatic Panc... Pancreatic Neop... Stage II Pancre... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Endoscopic Ultr... Fluorescence Im... Photodynamic Th... Quality-of-Life... Questionnaire A... Verteporfin	18 Years -	Mayo Clinic
Onvansertib in Combination With Gemcitabine and Nab-paclitaxel for the Treatment of Patients With Locally-advanced, Unresectable, or Metastatic Pancreatic Ductal Adenocarcinoma	NCT06398587	Locally Advance... Metastatic Panc... Stage II Pancre... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Onvansertib Gemcitabine Nab-paclitaxel Electrocardiogr... Magnetic Resona... Positron Emissi... Biospecimen Col... Biospecimen Col... Computed Tomogr...	18 Years -	OHSU Knight Cancer Institute
Testing the Addition of an Anti-cancer Drug, BAY 1895344, to Usual Chemotherapy for Advanced Stage Solid Tumors, With a Specific Focus on Patients With Small Cell Lung Cancer, Poorly Differentiated Neuroendocrine Cancer, and Pancreatic Cancer	NCT04514497	Metastatic Lung... Metastatic Mali... Metastatic Neur... Metastatic Panc... Stage III Lung ... Stage III Pancr... Stage IV Lung C... Stage IV Pancre... Unresectable Lu... Unresectable Ma... Unresectable Ne... Unresectable Pa...	Biopsy Biospecimen Col... Computed Tomogr... Elimusertib Irinotecan Hydr... Magnetic Resona... Topotecan Hydro...	18 Years -	National Cancer Institute (NCI)
Targeted Pathway Inhibition in Patients With Pancreatic Cancer	NCT04005690	Locally Advance... Metastatic Panc... Stage II Pancre... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Cobimetinib Olaparib Onvansertib Azenosertib	18 Years -	OHSU Knight Cancer Institute
Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas	NCT03925428	Advanced Lympho... Advanced Malign... Ann Arbor Stage... Ann Arbor Stage... Ann Arbor Stage... Ann Arbor Stage... Refractory B-Ce... Refractory Lymp... Refractory Mali... Refractory Panc... Refractory T-Ce... Stage II Pancre... Stage IIA Pancr... Stage IIB Pancr... Stage III Pancr... Stage IV Pancre... Unresectable Pa...	Entinostat Molibresib	12 Years -	National Cancer Institute (NCI)
Mesothelin-Specific T-Cells (FH-TCR-Tᴍsʟɴ) for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma	NCT04809766	Metastatic Panc... Stage IV Pancre...	Autologous Meso... Cyclophosphamid... Fludarabine Bendamustine	18 Years -	Fred Hutchinson Cancer Center
SD-101, Nivolumab, and Radiation Therapy in Treating Patients With Chemotherapy-Refractory Metastatic Pancreatic Cancer	NCT04050085	Metastatic Panc... Refractory Panc... Stage IV Pancre...	Nivolumab Radiation Thera... TLR9 Agonist SD...	18 Years -	University of California, Davis

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