Spots Global Cancer Trial Database for whole brain radiotherapy
Every month we try and update this database with for whole brain radiotherapy cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Evaluation of Repeated Whole Brain Radiotherapy Versus Best Supportive Care for Multiple Brain Metastases. | NCT03288272 | Brain Metastasa... | Whole Brain Rad... Best Supportive... | 18 Years - | Technical University of Munich | |
| Bevacizumab, Etoposide and Cisplatin Followed by Whole Brain Radiotherapy in Breast Cancer With Brain Metastases | NCT02185352 | Breast Cancer Brain Metastase... | BEEP regimen | 20 Years - 75 Years | National Taiwan University Hospital | |
| A Trial Comparing Radiosurgery With Surgery for Solitary Brain Metastases | NCT00124761 | Neoplasm Metast... Brain Neoplasm | Surgery + WBRT Radiosurgery + ... | 18 Years - | Royal Adelaide Hospital | |
| Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer | NCT03002532 | Breast Cancer M... Brain Metastase... | whole brain rad... | 18 Years - 75 Years | Affiliated Hospital to Academy of Military Medical Sciences | |
| New Combination of Chemoimmunotherapy for Systemic B-cell Lymphoma With Central Nervous System Involvement | NCT02329080 | Diffuse Large B... | Methotrexate Rituximab Cytarabine Thiotepa liposomial cyta... Etoposide Ifosfamide Carmustine whole brain rad... | 18 Years - 70 Years | International Extranodal Lymphoma Study Group (IELSG) | |
| Icotinib Combined With WBRT For NSCLC Patients With Brain Metastases and EGFR Mutation | NCT01516983 | Non-small Cell ... Brain Metastase... | icotinib Whole brain rad... | 18 Years - 75 Years | Betta Pharmaceuticals Co., Ltd. | |
| Hypofractionated Stereotactic Radiation Therapy of Brain Metastases: Evaluation of Whole-brain Radiotherapy | NCT02913534 | Brain Metastasi... | whole brain rad... | 18 Years - | Institut de Cancérologie de Lorraine | |
| EGFR-TKI Concurrent With/Without WBRT in Brain Metastasis From NSCLC | NCT02714010 | Non-Small Cell ... | EGFR-TKI whole brain rad... | 18 Years - 75 Years | Sun Yat-sen University | |
| WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER) | NCT04891471 | Neurocognitive ... Quality of Life Activities of D... | Stereotactic Ra... Whole Brain Irr... | 18 Years - | Mediterranean Institute of Oncology | |
| Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases | NCT00807170 | Non-small Cell ... | ZD6474 (Vandeta... Whole Brain Rad... ZD6474 ZD6474 | 18 Years - | Sanofi | |
| Neurocognitive Outcome of Conformal WBRT w/wo Hippocampal Avoidance for Brain Metastases | NCT02393131 | Metastatic Mali... | Hippocampal avo... Conformal WBRT | 20 Years - | National Taiwan University Hospital | |
| Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT | NCT04452084 | Brain Metastase... | HA-WBRT HA-SIB-WBRT | 21 Years - 80 Years | National Cancer Centre, Singapore | |
| Whole Brain Radiotherapy (WBRT) Versus Stereotactic Radiosurgery (SRS) for 4 Upto 10 Brain Metastases | NCT02353000 | Neoplasm Metast... | Stereotactic Ra... Whole Brain Rad... | 18 Years - | Maastricht Radiation Oncology | |
| New Combination of Chemoimmunotherapy for Systemic B-cell Lymphoma With Central Nervous System Involvement | NCT02329080 | Diffuse Large B... | Methotrexate Rituximab Cytarabine Thiotepa liposomial cyta... Etoposide Ifosfamide Carmustine whole brain rad... | 18 Years - 70 Years | International Extranodal Lymphoma Study Group (IELSG) | |
| Whole Brain Radiotherapy Following Local Treatment of Intracranial Metastases of Melanoma | NCT01503827 | Metastatic Mela... | WBRT | 18 Years - | Melanoma and Skin Cancer Trials Limited | |
| Neural Stem Cell Preserving Brain Radiation Therapy & Stereotactic Radiosurgery in Patients With 1-6 Brain Metastases | NCT00581113 | Lung Cancer Breast Cancer Prostate Cancer | Radiotherapy | 18 Years - | Virginia Commonwealth University | |
| Avelumab With Radiotherapy in Patients With Leptomeningeal Disease | NCT03719768 | Leptomeningeal ... Leptomeningeal ... | Avelumab Whole Brain Rad... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases | NCT00807170 | Non-small Cell ... | ZD6474 (Vandeta... Whole Brain Rad... ZD6474 ZD6474 | 18 Years - | Sanofi | |
| Avelumab With Radiotherapy in Patients With Leptomeningeal Disease | NCT03719768 | Leptomeningeal ... Leptomeningeal ... | Avelumab Whole Brain Rad... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Assess the Efficacy of Whole Brain Radiation Therapy in Lung Cancer Patients With Brain Metastasis | NCT01363557 | EGFR-mutated Lu... Brain Metastasi... | whole brain rad... Gefitinib (IRES... | 18 Years - | Assistance Publique - Hôpitaux de Paris | |
| Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis. | NCT00854867 | Solid Tumour Ne... Brain Metastase... | Whole Brain Rad... Whole brain rad... | 18 Years - | Mundipharma Research Limited | |
| The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases? | NCT05378633 | Brain Metastase... Nsclc | SRS Whole Brain Rad... | 18 Years - | University Hospital Heidelberg | |
| Assess the Efficacy of Whole Brain Radiation Therapy in Lung Cancer Patients With Brain Metastasis | NCT01363557 | EGFR-mutated Lu... Brain Metastasi... | whole brain rad... Gefitinib (IRES... | 18 Years - | Assistance Publique - Hôpitaux de Paris | |
| Stereotactic Radiosurgery vs Whole Brain Radiotherapy in Breast Cancer With Brain Oligometastasis | NCT05144867 | Breast Cancer Brain Metastase... Stereotactic Ra... Whole Brain Rad... | Stereotactic Ra... | 18 Years - 75 Years | PGIMER | |
| Evaluation of Repeated Whole Brain Radiotherapy Versus Best Supportive Care for Multiple Brain Metastases. | NCT03288272 | Brain Metastasa... | Whole Brain Rad... Best Supportive... | 18 Years - | Technical University of Munich | |
| Avelumab With Radiotherapy in Patients With Leptomeningeal Disease | NCT03719768 | Leptomeningeal ... Leptomeningeal ... | Avelumab Whole Brain Rad... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Whole-Brain Radiotherapy (WBRT) Versus WBRT and Integrated Boost Using Helical Tomotherapy for Multiple Brain Metastases | NCT00876759 | Brain Metastase... | whole brain rad... whole brain rad... | 18 Years - | University Hospital, Essen | |
| Stereotactic Radiosurgery vs Whole Brain Radiotherapy in Breast Cancer With Brain Oligometastasis | NCT05144867 | Breast Cancer Brain Metastase... Stereotactic Ra... Whole Brain Rad... | Stereotactic Ra... | 18 Years - 75 Years | PGIMER | |
| Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis. | NCT00854867 | Solid Tumour Ne... Brain Metastase... | Whole Brain Rad... Whole brain rad... | 18 Years - | Mundipharma Research Limited | |
| Investigating the Efficacy of Hair Sparing Radiotherapy Treatment to the Whole Brain. | NCT02213536 | Metastatic Brai... | VMAT (Volumetri... | 18 Years - | HCA International Limited | |
| Hypofractionated Stereotactic Radiation Therapy of Brain Metastases: Evaluation of Whole-brain Radiotherapy | NCT02913534 | Brain Metastasi... | whole brain rad... | 18 Years - | Institut de Cancérologie de Lorraine | |
| Safety and Tolerability of Low-Dose Temozolomide During Whole Brain Radiation in Patients With Cerebral Metastases From Non-Small-Cell Lung Cancer (Study P04071)(TERMINATED) | NCT00266812 | Carcinoma, Non-... | Temozolomide an... Whole brain rad... | 18 Years - | Merck Sharp & Dohme LLC | |
| Study to Demonstrate the Safety of WBR Administered at the Same Time as Intrathecal Liposomal Cytarabine (DepoCyte®) Versus Intrathecal Liposomal Cytarabine (DepoCyte®) Administered After WBR for the Treatment of Solid Tumour Neoplastic Meningitis in Patients With or Without Brain Metastasis. | NCT00854867 | Solid Tumour Ne... Brain Metastase... | Whole Brain Rad... Whole brain rad... | 18 Years - | Mundipharma Research Limited | |
| Investigating the Efficacy of Hair Sparing Radiotherapy Treatment to the Whole Brain. | NCT02213536 | Metastatic Brai... | VMAT (Volumetri... | 18 Years - | HCA International Limited |
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