Spots Global Cancer Trial Database for stage iva lung cancer ajcc v8

Every month we try and update this database with for stage iva lung cancer ajcc v8 cancer trials from around the world to help patients and their families find trials that might be right for them.
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We do not endorse or review these studies in any way.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Adaptive Radiation Planning for the Reduction of Radiation-Induced Toxicity in Patients With Stage II-IV Non-small Cell Lung Cancer	NCT04751747	Locally Advance... Metastatic Lung... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Unresectable Lu...	Computed Tomogr... Contrast Agent	18 Years -	Rutgers, The State University of New Jersey
Poziotinib and Ramucirumab for the Treatment of EGFR Exon 20 Mutant Stage IV Non-small Cell Lung Cancer	NCT05045404	Metastatic Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Poziotinib Hydr... 1429757-68-5, H...	18 Years -	M.D. Anderson Cancer Center
EMB-01 in Combination With Osimertinib in Patients With EGFR Mutant Lung Cancer	NCT05498389	Metastatic Lung... Advanced Lung N... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... EGFR Mutation-R...	EMB-01 Osimertinib	18 Years -	Shanghai EpimAb Biotherapeutics Co., Ltd.
Local Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer	NCT03707938	Advanced Lung C... ALK Gene Rearra... Lung Non-Small ... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Brigatinib Local Consolida...	18 Years -	M.D. Anderson Cancer Center
Testing the Combination of MLN4924 (Pevonedistat), Carboplatin, and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) Who Have Previously Been Treated With Immunotherapy	NCT03965689	Metastatic Lung... Metastatic Lung... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Unresectable Lu... Unresectable Lu...	Carboplatin Paclitaxel Pevonedistat	18 Years -	National Cancer Institute (NCI)
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases	NCT04752267	Anatomic Stage ... Clinical Stage ... Glioma Malignant Brain... Metastatic Brea... Metastatic Colo... Metastatic Kidn... Metastatic Lung... Metastatic Mali... Metastatic Mela... Pathologic Stag... Prognostic Stag... Stage IV Colon ... Stage IV Lung C... Stage IV Renal ... Stage IVA Colon... Stage IVA Lung ... Stage IVB Colon... Stage IVB Lung ... Stage IVC Colon...	Computed Tomogr... 18F-FMAU Multiparametric... Positron Emissi...	18 Years -	University of Southern California
Single Fraction Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Non-small Cell Lung Cancer	NCT04073745	Lung Non-Small ... Positive Surgic... Resected Mass Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Quality-of-Life... Questionnaire A... Stereotactic Bo...	18 Years -	Roswell Park Cancer Institute
Supportive Care Intervention (ROAR-LCT) for Patients With Stage IIIA, IIIB, and IV Lung Cancer, ROAR-LCT Trial	NCT05339022	Advanced Lung N... Advanced Lung S... Extensive Stage... Stage IIIA Lung... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Unresectable Lu... Unresectable Lu...	Best Practice Exercise Interv... Physical Therap... Quality-of-Life... Questionnaire A... Relaxation Ther...	60 Years -	Ohio State University Comprehensive Cancer Center
Aurora Kinase Inhibitor LY3295668 in Combination With Osimertinib for the Treatment of Advanced or Metastatic EGFR-Mutant Non-squamous Non-small Cell Lung Cancer	NCT05017025	Advanced Lung N... Metastatic Lung... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Aurora A Kinase... Osimertinib	18 Years -	M.D. Anderson Cancer Center
4D PET/CT in Diagnosing Participants With Lung and Colorectal Cancer With Liver and Lung Metastasis	NCT00862680	Metastatic Mali... Metastatic Mali... Stage IV Colore... Stage IV Lung C... Stage IVA Color... Stage IVA Lung ... Stage IVB Color... Stage IVB Lung ... Stage IVC Color...	4-Dimensional C... 4D PET Scan	18 Years -	M.D. Anderson Cancer Center
Genetics and Shared Decision Making in Improving Care for Patients With Stage IVA-C Non-small Cell Lung Cancer	NCT03944265	Activating ALK ... Activating EGFR... Activating ROS1... Health Care Pro... Lung Non-Small ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Counseling Questionnaire A... Medical Chart R...	18 Years -	Thomas Jefferson University
Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced Malignancies	NCT02419495	Advanced Malign... Clinical Stage ... Clinical Stage ... Fallopian Tube ... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Ovarian Carcino... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Primary Periton... Stage III Lung ... Stage III Renal... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ... Triple-Negative... Unresectable Lu... Unresectable Me... Unresectable Re...	Capecitabine Carboplatin Cyclophosphamid... Doxorubicin Eribulin Fluorouracil Ipilimumab Irinotecan Hydr... Leucovorin Calc... Nivolumab Olaparib Oxaliplatin Paclitaxel Pembrolizumab Pemetrexed Selinexor Topotecan	18 Years -	M.D. Anderson Cancer Center
A Biobehavioral/Cognitive Treatment for Stress, Depression, and Anxiety in Patients With Stage IV Lung Cancer	NCT05342571	Advanced Lung C... Metastatic Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Behavioral, Psy... Biospecimen Col... Electronic Heal... Informational I... Survey Administ...	18 Years -	Ohio State University Comprehensive Cancer Center
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability	NCT04804644	Metastatic Lung... Metastatic Mali... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Memantine Hydro... Neurocognitive ... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery	NCT04588246	Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ...	Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies	NCT03590054	Stage III Cutan... Stage IV Cutane... Locally Advance... Locally Advance... Metastatic Head... Metastatic Mali... Metastatic Mela... Metastatic Urot... Non-Small Cell ... Stage IB Lung C... Stage III Cutan... Stage III Lung ... Stage III Urete... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Cutane... Stage IV Lung C... Stage IV Ureter... Stage IVA Lung ... Stage IVB Lung ...	Abexinostat Pembrolizumab	18 Years -	University of California, San Francisco
Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)	NCT04625647	Lung Adenocarci... Lung Non-Small ... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Sotorasib	18 Years -	SWOG Cancer Research Network
Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors	NCT04771520	Anatomic Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Metastatic Mali... Metastatic Mela... Metastatic Prim... Metastatic Sarc... Pathologic Stag... Pathologic Stag... Pathologic Stag... Postneoadjuvant... Postneoadjuvant... Postneoadjuvant... Prognostic Stag... Prognostic Stag... Stage IIIC Colo... Stage IIIC Lung... Stage IV Colore... Stage IV Lung C... Stage IVA Color... Stage IVA Lung ... Stage IVB Color... Stage IVB Lung ... Stage IVC Color...	Avapritinib	18 Years -	M.D. Anderson Cancer Center
Ramucirumab and Pembrolizumab for the Treatment of EGFR Mutant Recurrent or Metastatic Non-small Cell Lung Cancer	NCT04120454	Metastatic Lung... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Pembrolizumab Ramucirumab	18 Years -	Ohio State University Comprehensive Cancer Center
Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study	NCT04430725	Lung Non-Small ... Metastatic Colo... Metastatic Sarc... Stage I Lung Ca... Stage IA1 Lung ... Stage IA2 Lung ... Stage IA3 Lung ... Stage IB Lung C... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Colore... Stage IV Lung C... Stage IVA Color... Stage IVA Lung ... Stage IVB Color... Stage IVB Lung ... Stage IVC Color...	Computed Tomogr... Microwave Ablat... Questionnaire A... Wedge Excision	18 Years -	M.D. Anderson Cancer Center
Testing the Use of Targeted Treatment for RET Positive Advanced Non-small Cell Lung Cancer	NCT05364645	Lung Non-Small ... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Carboplatin Pemetrexed Selpercatinib	18 Years -	SWOG Cancer Research Network
Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer	NCT03737994	Lung Non-Squamo... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Alectinib Brigatinib Carboplatin Ceritinib Cisplatin Crizotinib Ensartinib Lorlatinib Pemetrexed	18 Years -	National Cancer Institute (NCI)
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery	NCT04588246	Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ...	Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Hypofractionated Radiation Therapy After Durvalumab and Chemotherapy for the Treatment of Stage IV Extensive Stage Small Cell Lung Cancer, CASPIAN-RT Trial	NCT05161533	Extensive Stage... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Carboplatin Cisplatin Durvalumab Etoposide Hypofractionate... Quality-of-Life... Questionnaire A...	18 Years -	University of Washington
Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal Cancer	NCT02983578	Advanced Colore... Advanced Lung N... Lung Non-Small ... Mismatch Repair... Refractory Colo... Refractory Lung... Refractory Panc... Stage II Pancre... Stage III Color... Stage III Lung ... Stage III Pancr... Stage IIIA Colo... Stage IIIA Lung... Stage IIIB Colo... Stage IIIB Lung... Stage IIIC Colo... Stage IIIC Lung... Stage IV Colore... Stage IV Lung C... Stage IV Pancre... Stage IVA Color... Stage IVA Lung ... Stage IVB Color... Stage IVB Lung ... Stage IVC Color...	Danvatirsen Durvalumab	18 Years -	M.D. Anderson Cancer Center
Resiliency Among Older Adults Receiving Lung Cancer Treatment	NCT04229381	Advanced Lung C... Extensive Stage... Stage IIIA Lung... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Unresectable Lu... Unresectable Lu...	Physical Therap... Quality-of-Life... Questionnaire A... Relaxation Ther...	60 Years -	Ohio State University Comprehensive Cancer Center
Subcutaneous Atezolizumab for the Treatment of Non-small Cell Lung Cancer	NCT05340309	Lung Non-Small ... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Atezolizumab an... Survey Administ...	18 Years -	University of Southern California
Dyadic Yoga Intervention in Improving Physical Performance and Quality of Life in Patients With Stage I-IV Non-small Cell Lung or Esophageal Cancer Undergoing Radiotherapy and Their Caregivers	NCT03948100	Esophageal Carc... Lung Non-Small ... Stage I Lung Ca... Stage IA1 Lung ... Stage IA2 Lung ... Stage IA3 Lung ... Stage IB Lung C... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Educational Int... Quality-of-Life... Questionnaire A... Yoga	18 Years -	M.D. Anderson Cancer Center
Low-Dose Interleukin-2 and Pembrolizumab for the Treatment of Stage IV Non-Small Cell Lung Cancer	NCT05493566	Lung Non-Small ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Aldesleukin Pembrolizumab	18 Years -	Emory University
Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study	NCT03707574	Advanced Malign... Advanced Melano... Advanced Renal ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Anatomic Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Prognostic Stag... Stage III Color... Stage III Lung ... Stage III Ovari... Stage III Prost... Stage IIIA Colo... Stage IIIA Lung... Stage IIIA Ovar... Stage IIIA Pros... Stage IIIA1 Ova... Stage IIIA2 Ova... Stage IIIB Colo... Stage IIIB Lung... Stage IIIB Ovar... Stage IIIB Pros... Stage IIIC Colo... Stage IIIC Lung... Stage IIIC Ovar... Stage IIIC Pros... Stage IV Colore... Stage IV Lung C... Stage IV Ovaria... Stage IV Prosta... Stage IVA Color... Stage IVA Lung ... Stage IVA Ovari... Stage IVA Prost... Stage IVB Color... Stage IVB Lung ... Stage IVB Ovari... Stage IVB Prost... Stage IVC Color...	Biospecimen Col...	18 Years -	National Cancer Institute (NCI)
PBF-1129 and Nivolumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer	NCT05234307	Metastatic Lung... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Adenosine A2B R... Biospecimen Col... Nivolumab	18 Years -	Ohio State University Comprehensive Cancer Center
Local Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer	NCT03707938	Advanced Lung C... ALK Gene Rearra... Lung Non-Small ... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Brigatinib Local Consolida...	18 Years -	M.D. Anderson Cancer Center
Necitumumab and Trastuzumab in Combination With Osimertinib for the Treatment of Refractory Epidermal Growth Factor Receptor (EGFR)-Mutated Stage IV Non-small Cell Lung Cancer	NCT04285671	Metastatic Lung... Refractory Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Necitumumab Osimertinib Quality-of-Life... Questionnaire A... Trastuzumab	18 Years -	Jonsson Comprehensive Cancer Center
Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer	NCT04479306	Recurrent Lung ... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Alisertib Osimertinib Sapanisertib	18 Years -	M.D. Anderson Cancer Center
Geriatric and Quality of Life Assessments in Older Patients With Non-metastatic or Metastatic Head and Neck or Lung Cancer Undergoing Surgery or Chemoradiation and Their Caregivers	NCT03902535	Caregiver Head and Neck C... Lung Carcinoma Metastatic Head... Metastatic Lung... Stage 0 Lung Ca... Stage I Lung Ca... Stage IA1 Lung ... Stage IA2 Lung ... Stage IA3 Lung ... Stage IB Lung C... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Comprehensive G... Quality-of-Life... Questionnaire A...	21 Years -	City of Hope Medical Center
Local Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer	NCT03707938	Advanced Lung C... ALK Gene Rearra... Lung Non-Small ... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Brigatinib Local Consolida...	18 Years -	M.D. Anderson Cancer Center
Remote Monitoring With Health-Coaching for Lifestyle Changes in Patients With Lung Cancer Related Fatigue	NCT05407038	Advanced Lung N... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Exercise Counse... Exercise Interv... Internet-Based ... Interview Medical Device ... Questionnaire A...	18 Years -	Mayo Clinic
Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer	NCT04919382	Extensive Stage... Metastatic Lung... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Atezolizumab Temozolomide	18 Years -	Big Ten Cancer Research Consortium
Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors	NCT02589522	Metastatic Lung... Metastatic Lung... Metastatic Lung... Metastatic Mali... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Berzosertib Quality-of-Life... Therapeutic Con... Whole-Brain Rad...	18 Years -	National Cancer Institute (NCI)
Tocilizumab, Ipilimumab, and Nivolumab for the Treatment of Advanced Melanoma, Non-Small Cell Lung Cancer, or Urothelial Carcinoma	NCT04940299	Clinical Stage ... Clinical Stage ... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Malignant Solid... Metastatic Blad... Metastatic Blad... Metastatic Lung... Metastatic Mela... Metastatic Rena... Metastatic Uret... Metastatic Uret... Metastatic Uret... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Stage III Bladd... Stage III Lung ... Stage III Renal... Stage III Urete... Stage III Ureth... Stage IIIA Blad... Stage IIIA Lung... Stage IIIB Blad... Stage IIIB Lung... Stage IIIC Lung... Stage IV Bladde... Stage IV Lung C... Stage IV Renal ... Stage IV Ureter... Stage IV Urethr... Stage IVA Lung ... Stage IVB Lung ... Unresectable Me...	Ipilimumab Nivolumab Tocilizumab	18 Years -	M.D. Anderson Cancer Center
Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis	NCT04516070	Metastatic Lung... Metastatic Mali... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Questionnaire A... Stereotactic Ra...	18 Years -	M.D. Anderson Cancer Center
Phase 2 DoceRamPem for Patients With Metastatic or Recurrent NSCLC Who Progressed on Platinum-Doublet and PD-1/PD-L1 Blockade	NCT04340882	Metastatic Non-... Recurrent Non-S... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Docetaxel Pembrolizumab Ramucirumab	18 Years -	Emory University
Tumor Treating Fields (TTFields) Therapy to Manage Brain Metastases in Small Cell Lung Cancer	NCT03995667	Extensive Stage... Limited Stage L... Stage I Lung Ca... Stage IA1 Lung ... Stage IA2 Lung ... Stage IA3 Lung ... Stage IB Lung C... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Questionnaire A... Tumor Treating ...	22 Years -	OHSU Knight Cancer Institute
Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors	NCT05334329	Advanced Lung N... Metastatic Lung... Recurrent Lung ... Refractory Lung... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Antineoplastic ... Atezolizumab Biospecimen Col... Cyclophosphamid... Fludarabine	18 Years -	City of Hope Medical Center
4D PET/CT in Diagnosing Participants With Lung and Colorectal Cancer With Liver and Lung Metastasis	NCT00862680	Metastatic Mali... Metastatic Mali... Stage IV Colore... Stage IV Lung C... Stage IVA Color... Stage IVA Lung ... Stage IVB Color... Stage IVB Lung ... Stage IVC Color...	4-Dimensional C... 4D PET Scan	18 Years -	M.D. Anderson Cancer Center
Tumor Treating Fields (TTFields) Therapy to Manage Brain Metastases in Small Cell Lung Cancer	NCT03995667	Extensive Stage... Limited Stage L... Stage I Lung Ca... Stage IA1 Lung ... Stage IA2 Lung ... Stage IA3 Lung ... Stage IB Lung C... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Questionnaire A... Tumor Treating ...	22 Years -	OHSU Knight Cancer Institute
A Biobehavioral/Cognitive Treatment for Stress, Depression, and Anxiety in Patients With Stage IV Lung Cancer	NCT05342571	Advanced Lung C... Metastatic Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Behavioral, Psy... Biospecimen Col... Electronic Heal... Informational I... Survey Administ...	18 Years -	Ohio State University Comprehensive Cancer Center
Bintrafusp Alfa With Chemotherapy for Tyrosine Kinase Inhibitor-Resistant EGFR-Mutant Non-small Cell Lung Cancer	NCT04971187	Locally Advance... Metastatic Lung... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Unresectable Lu...	Bintrafusp Alfa Pemetrexed Carboplatin Cisplatin	18 Years -	M.D. Anderson Cancer Center
Brigatinib and Bevacizumab for the Treatment of ALK-Rearranged Locally Advanced, Metastatic, or Recurrent NSCLC	NCT04227028	Locally Advance... Metastatic Lung... Recurrent Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Bevacizumab Brigatinib	18 Years -	City of Hope Medical Center
Role of Gut Microbiome and Fecal Transplant on Medication-Induced GI Complications in Patients With Cancer	NCT03819296	Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Colitis Lung Non-Small ... Malignant Genit... Malignant Solid... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Stage 0 Lung Ca... Stage I Lung Ca... Stage IA1 Lung ... Stage IA2 Lung ... Stage IA3 Lung ... Stage IB Lung C... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Best Practice Biospecimen Col... Endoscopic Proc... Fecal Microbiot... Infliximab Laboratory Biom... Prednisone Vedolizumab	18 Years -	M.D. Anderson Cancer Center
EMB-01 in Combination With Osimertinib in Patients With EGFR Mutant Lung Cancer	NCT05498389	Metastatic Lung... Advanced Lung N... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... EGFR Mutation-R...	EMB-01 Osimertinib	18 Years -	Shanghai EpimAb Biotherapeutics Co., Ltd.
Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial	NCT04728230	Extensive Stage... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Carboplatin Durvalumab Etoposide Olaparib Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Platinum-Based Chemotherapy and Durvalumab for the Treatment of Stage IIIB or IV Non-small Cell Lung Cancer	NCT04262869	Lung Non-Small ... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Carboplatin Durvalumab Paclitaxel Pemetrexed	18 Years -	Emory University
Testing of TAK228 (MLN0128, Sapanisertib) Plus Docetaxel to the Usual Standard of Care for Advanced Squamous Cell Lung Cancer (A Lung-MAP Treatment Trial)	NCT04267913	Lung Squamous C... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Dexamethasone Docetaxel Ramucirumab Sapanisertib	-	SWOG Cancer Research Network
Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies	NCT04902040	Advanced Bladde... Advanced Lung N... Advanced Malign... Advanced Melano... Advanced Merkel... Advanced Renal ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Stage III Bladd... Stage III Lung ... Stage III Renal... Stage IIIA Blad... Stage IIIA Lung... Stage IIIB Blad... Stage IIIB Lung... Stage IIIC Lung... Stage IV Bladde... Stage IV Lung C... Stage IV Renal ... Stage IVA Bladd... Stage IVA Lung ... Stage IVB Bladd... Stage IVB Lung ...	Atezolizumab Avelumab Durvalumab Nivolumab Pembrolizumab Plinabulin Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial	NCT04728230	Extensive Stage... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Carboplatin Durvalumab Etoposide Olaparib Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases	NCT04752267	Anatomic Stage ... Clinical Stage ... Glioma Malignant Brain... Metastatic Brea... Metastatic Colo... Metastatic Kidn... Metastatic Lung... Metastatic Mali... Metastatic Mela... Pathologic Stag... Prognostic Stag... Stage IV Colon ... Stage IV Lung C... Stage IV Renal ... Stage IVA Colon... Stage IVA Lung ... Stage IVB Colon... Stage IVB Lung ... Stage IVC Colon...	Computed Tomogr... 18F-FMAU Multiparametric... Positron Emissi...	18 Years -	University of Southern California
Supportive Care Intervention (ROAR-LCT) for Patients With Stage IIIA, IIIB, and IV Lung Cancer, ROAR-LCT Trial	NCT05339022	Advanced Lung N... Advanced Lung S... Extensive Stage... Stage IIIA Lung... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Unresectable Lu... Unresectable Lu...	Best Practice Exercise Interv... Physical Therap... Quality-of-Life... Questionnaire A... Relaxation Ther...	60 Years -	Ohio State University Comprehensive Cancer Center
Genetics and Shared Decision Making in Improving Care for Patients With Stage IVA-C Non-small Cell Lung Cancer	NCT03944265	Activating ALK ... Activating EGFR... Activating ROS1... Health Care Pro... Lung Non-Small ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Counseling Questionnaire A... Medical Chart R...	18 Years -	Thomas Jefferson University
Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted Antibodies	NCT04902040	Advanced Bladde... Advanced Lung N... Advanced Malign... Advanced Melano... Advanced Merkel... Advanced Renal ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Clinical Stage ... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Pathologic Stag... Stage III Bladd... Stage III Lung ... Stage III Renal... Stage IIIA Blad... Stage IIIA Lung... Stage IIIB Blad... Stage IIIB Lung... Stage IIIC Lung... Stage IV Bladde... Stage IV Lung C... Stage IV Renal ... Stage IVA Bladd... Stage IVA Lung ... Stage IVB Bladd... Stage IVB Lung ...	Atezolizumab Avelumab Durvalumab Nivolumab Pembrolizumab Plinabulin Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability	NCT04804644	Metastatic Lung... Metastatic Mali... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Memantine Hydro... Neurocognitive ... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial	NCT04728230	Extensive Stage... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Carboplatin Durvalumab Etoposide Olaparib Radiation Thera...	18 Years -	M.D. Anderson Cancer Center
Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME Study	NCT05022394	Lung Non-Small ... Recurrent Lung ... Stage I Lung Ca... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Nivolumab Sapanisertib	18 Years -	M.D. Anderson Cancer Center
Hypofractionated Radiation Therapy After Durvalumab and Chemotherapy for the Treatment of Stage IV Extensive Stage Small Cell Lung Cancer, CASPIAN-RT Trial	NCT05161533	Extensive Stage... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Carboplatin Cisplatin Durvalumab Etoposide Hypofractionate... Quality-of-Life... Questionnaire A...	18 Years -	University of Washington
Poziotinib and Ramucirumab for the Treatment of EGFR Exon 20 Mutant Stage IV Non-small Cell Lung Cancer	NCT05045404	Metastatic Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Poziotinib Hydr... 1429757-68-5, H...	18 Years -	M.D. Anderson Cancer Center
Online Psychosocial Intervention in Improving Social Well-Being and Support in Women With Stage I-IV Non-small Cell Lung Cancer Undergoing Treatment	NCT03731585	Non-Small Cell ... Stage I Lung Ca... Stage IA1 Lung ... Stage IA2 Lung ... Stage IA3 Lung ... Stage IB Lung C... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Behavioral Inte... Educational Int... Questionnaire A... Support Group T...	18 Years -	M.D. Anderson Cancer Center
Supportive Care Intervention (ROAR-LCT) for Patients With Stage IIIA, IIIB, and IV Lung Cancer, ROAR-LCT Trial	NCT05339022	Advanced Lung N... Advanced Lung S... Extensive Stage... Stage IIIA Lung... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Unresectable Lu... Unresectable Lu...	Best Practice Exercise Interv... Physical Therap... Quality-of-Life... Questionnaire A... Relaxation Ther...	60 Years -	Ohio State University Comprehensive Cancer Center
Evaluating Modifiable Biomarkers for the Prediction of Immunotherapy Response and Toxicity	NCT04954885	Lung Non-Squamo... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Biospecimen Col... Physical Perfor... Physical Perfor... Questionnaire A...	18 Years -	Ohio State University Comprehensive Cancer Center
Resiliency Among Older Adults Receiving Lung Cancer Treatment	NCT04229381	Advanced Lung C... Extensive Stage... Stage IIIA Lung... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ... Unresectable Lu... Unresectable Lu...	Physical Therap... Quality-of-Life... Questionnaire A... Relaxation Ther...	60 Years -	Ohio State University Comprehensive Cancer Center
Family Caregivers in Underserved Populations Providing Complex Cancer Care	NCT05213078	Malignant Femal... Stage 0 Lung Ca... Stage I Lung Ca... Stage IA1 Lung ... Stage IA2 Lung ... Stage IA3 Lung ... Stage IB Lung C... Stage II Lung C... Stage IIA Lung ... Stage IIB Lung ... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Educational Int... Quality-of-Life... Questionnaire A...	18 Years -	City of Hope Medical Center
A Video Intervention to Improve Patient Understanding of Tumor Genomic Testing in Patients With Metastatic Cancer	NCT05215769	Anatomic Stage ... Metastatic Brea... Metastatic Lung... Metastatic Mali... Prognostic Stag... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Health Educatio... Questionnaire A...	18 Years -	Ohio State University Comprehensive Cancer Center
Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery	NCT04588246	Anatomic Stage ... Metastatic Brea... Metastatic Dige... Metastatic Lung... Metastatic Mali... Metastatic Mela... Metastatic Rena... Prognostic Stag... Recurrent Brain... Stage IV Lung C... Stage IV Renal ... Stage IVA Lung ... Stage IVB Lung ...	Memantine Quality-of-Life... Questionnaire A... Stereotactic Ra... Whole-Brain Rad...	18 Years -	NRG Oncology
Testing the Effects of MK-3475 (Pembrolizumab) With or Without the Usual Chemotherapy Treatment for Patients 70 Years of Age and Older With Advanced Non-small Cell Lung Cancer	NCT04533451	Metastatic Lung... Metastatic Lung... Recurrent Lung ... Recurrent Lung ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Pembrolizumab Pemetrexed Carboplatin Comprehensive G... Questionnaire A... Quality-of-Life...	70 Years -	Alliance for Clinical Trials in Oncology
Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors	NCT05334329	Advanced Lung N... Metastatic Lung... Recurrent Lung ... Refractory Lung... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Antineoplastic ... Atezolizumab Biospecimen Col... Cyclophosphamid... Fludarabine	18 Years -	City of Hope Medical Center
Osimertinib in Combination With Alisertib or Sapanisertib for the Treatment of Osimertinib-Resistant EGFR Mutant Stage IIIB or IV Non-Small Cell Lung Cancer	NCT04479306	Recurrent Lung ... Stage IIIB Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Alisertib Osimertinib Sapanisertib	18 Years -	M.D. Anderson Cancer Center
CCL21-Gene Modified Dendritic Cell Vaccine and Pembrolizumab in Treating Patients With Stage IV Non-small Cell Lung Cancer	NCT03546361	Lung Non-Small ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Autologous Dend... Pembrolizumab	18 Years -	Jonsson Comprehensive Cancer Center
Bronchoscopic Laser Ablation of Peripheral Lung Tumors	NCT03707925	Lung Carcinoid ... Lung Non-Small ... Metastatic Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Cone-Beam Compu... Conventional Su... Laser Ablation	18 Years -	M.D. Anderson Cancer Center
CCL21-Gene Modified Dendritic Cell Vaccine and Pembrolizumab in Treating Patients With Stage IV Non-small Cell Lung Cancer	NCT03546361	Lung Non-Small ... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Autologous Dend... Pembrolizumab	18 Years -	Jonsson Comprehensive Cancer Center
A Nurse-Led Intervention for Fear of Progression in Advanced Cancer	NCT04819997	Advanced Lung C... Metastatic Mali... Stage III Lung ... Stage IIIA Lung... Stage IIIB Lung... Stage IIIC Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Educational Int...	-	City of Hope Medical Center
Poziotinib and Ramucirumab for the Treatment of EGFR Exon 20 Mutant Stage IV Non-small Cell Lung Cancer	NCT05045404	Metastatic Lung... Stage IV Lung C... Stage IVA Lung ... Stage IVB Lung ...	Poziotinib Hydr... 1429757-68-5, H...	18 Years -	M.D. Anderson Cancer Center

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