Spots Global Cancer Trial Database for enzyme inhibitors
Every month we try and update this database with for enzyme inhibitors cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto | NCT05874921 | Urothelial Carc... Urothelial Carc... Urothelial Carc... Urothelial Carc... Urothelial Canc... Urothelial Carc... Carcinoma, Tran... Transitional Ce... | Jelmyto (mitomy... | 18 Years - | UroGen Pharma Ltd. | |
| A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement | NCT04543188 | Malignant Melan... Carcinoma, Non-... Brain Neoplasms... Brain Neoplasms Malignant Neopl... | PF-07284890 Binimetinib Midazolam | 16 Years - | Pfizer | |
| A Phase 1b/2 Study in Asian Subjects With Non-Small Cell Lung Cancer | NCT01039948 | Carcinoma, Non-... Lung Neoplasms Lung Cancer Respiratory Tra... | AV-299 + gefiti... Gefitinib | 18 Years - | AVEO Pharmaceuticals, Inc. | |
| A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma | NCT03150862 | Brain and Centr... | Pamiparib TMZ Radiation | 18 Years - | BeiGene | |
| Savolitinib vs. Sunitinib in MET-driven PRCC. | NCT03091192 | Carcinoma Carcinoma, Rena... Kidney Neoplasm... Urologic Neopla... Kidney Diseases Neoplasms by Si... Enzyme Inhibito... Protein Kinase ... | Savolitinib Sunitinib | 18 Years - 130 Years | AstraZeneca | |
| Study of Azacitidine in Adult Taiwanese Subjects With Higher-Risk Myelodysplastic Syndromes (MDS) | NCT01201811 | Myelodysplastic... | Azacitidine | 18 Years - | Celgene | |
| An Extended Feasibility Phase I/II Study of Methylenetetrahydrofolate (Arfolitixorin) and Pemetrexed Single Agent, Given as Neoadjuvant Treatment in Patients With Resectable Rectal Cancer | NCT01397305 | Rectal Cancer | [6R] 5,10-methy... Pemetrexed | 18 Years - | Isofol Medical AB | |
| Prospective Observational Study Of Patients With Polycythemia Vera In US Clinical Practices (REVEAL) | NCT02252159 | MPN (Myeloproli... | 18 Years - | Incyte Corporation | ||
| Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC) | NCT01009593 | Hepatocellular ... Hepatocellular ... Carcinoma, Hepa... Liver Diseases Neoplasms by Hi... Digestive Syste... Carcinoma Liver Neoplasms Neoplasms Neoplasms by Si... Digestive Syste... Adenocarcinoma Neoplasms, Glan... | ABT-869 Sorafenib | 18 Years - | Abbott | |
| Hydroxychloroquine Sulfate Alleviates Persistent Proteinuria in IgA Nephropathy | NCT02765594 | Primary IgA Nep... | Hydroxychloroqu... Valsartan | 18 Years - 60 Years | Peking Union Medical College Hospital | |
| A Study of KX2-391 With Paclitaxel in Patients With Solid Tumors | NCT01764087 | Unspecified Adu... Gastric Cancer Breast Cancer | KX2-391 and Pac... | 20 Years - | Hanmi Pharmaceutical Company Limited | |
| Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC) | NCT01009593 | Hepatocellular ... Hepatocellular ... Carcinoma, Hepa... Liver Diseases Neoplasms by Hi... Digestive Syste... Carcinoma Liver Neoplasms Neoplasms Neoplasms by Si... Digestive Syste... Adenocarcinoma Neoplasms, Glan... | ABT-869 Sorafenib | 18 Years - | Abbott | |
| SU5416 in Patients With AIDS-Related Kaposi's Sarcoma Who Have Not Responded to Treatment | NCT00005931 | Sarcoma, Kaposi HIV Infections | SU5416 | 18 Years - | NIH AIDS Clinical Trials Information Service | |
| Study of Vorinostat (MK-0683) or Placebo, in Combination With Bortezomib in Participants With Multiple Myeloma (MK-0683-088 AMN) | NCT00773747 | Multiple Myelom... | Vorinostat bortezomib placebo to vori... | 18 Years - | Merck Sharp & Dohme LLC | |
| A Phase 1b/2 Study in Asian Subjects With Non-Small Cell Lung Cancer | NCT01039948 | Carcinoma, Non-... Lung Neoplasms Lung Cancer Respiratory Tra... | AV-299 + gefiti... Gefitinib | 18 Years - | AVEO Pharmaceuticals, Inc. | |
| Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer | NCT00838578 | Colorectal Canc... | KRN330 Irinotecan | 18 Years - | Kyowa Kirin Co., Ltd. | |
| Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA | NCT01550510 | Stage IV Colore... | Ascorbic Acid Irinotecan | 18 Years - | Thomas Jefferson University | |
| A Prospective Open Label Comparative Dose Ranging Study Evaluating the Effect of Pre-TURBT Intravesical Instillation of Mitomycin C (MMC) Mixed With TC-3 Gel in Patients With Non Muscle Invasive Bladder Cancer (NMIBC) | NCT01799499 | Non Muscle Inva... | TC-3 hydrogel TC-3 hydrogel TC-3 hydrogel | 21 Years - | UroGen Pharma Ltd. | |
| Drug Interaction Study of Apixaban With Cyclosporine and Tacrolimus | NCT03083782 | Venous Thromboe... Pharmacokinetic... Healthy | Apixaban alone Cyclosporine Tacrolimus Apixaban Apixaban | 18 Years - 55 Years | Thomas Jefferson University | |
| A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients With Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma | NCT05494866 | CYP3A Inhibitor Advanced Stage ... Pancreatic Canc... Pancreatic Aden... Pancreatic Neop... | Cobicistat Oral... Gemcitabin Nab paclitaxel | 18 Years - | German Cancer Research Center | |
| A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients With Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma | NCT05494866 | CYP3A Inhibitor Advanced Stage ... Pancreatic Canc... Pancreatic Aden... Pancreatic Neop... | Cobicistat Oral... Gemcitabin Nab paclitaxel | 18 Years - | German Cancer Research Center | |
| An Open Label Study of Postmenopausal Women With Oestrogen Receptor Positive Locally Advanced or Metastatic Breast Cancer Treated With Everolimus (RAD001) With Exemestane, With Exploratory Epigenetic Marker Analysis | NCT01743560 | Oestrogen Recep... | RAD001 Exemestane | 18 Years - | Novartis | |
| Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA | NCT01550510 | Stage IV Colore... | Ascorbic Acid Irinotecan | 18 Years - | Thomas Jefferson University |
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