Spots Global Cancer Trial Database for hypofractionation
Every month we try and update this database with for hypofractionation cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Ion Irradiation of Sacrococcygeal Chordoma | NCT01811394 | Sacral Chordoma | protons carbon ions | 18 Years - 80 Years | Heidelberg University | |
| SIGNAL During a COVID-19 Pandemic | NCT05037019 | Breast Cancer | Radiation thera... | 50 Years - | Lawson Health Research Institute | |
| Hypofractionated Radiotherapy as Primary Therapy for Prostate Cancer | NCT01921803 | Prostate Cancer | hypofractionati... | 40 Years - 80 Years | University Hospital, Ghent | |
| Hypofractionation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma | NCT06344130 | Astrocytoma Glioma Recurrent Gliob... | Radiation Thera... | 18 Years - 120 Years | National Institutes of Health Clinical Center (CC) | |
| Moderate Hypofractionated Boost to the Prostate With Pelvic RT in High Risk Prostate Cancer | NCT05313815 | Prostate Cancer | Moderate hypofr... | 18 Years - | University Health Network, Toronto | |
| Ion Prostate Irradiation | NCT01641185 | Prostatic Neopl... | radiation | 40 Years - 80 Years | Heidelberg University | |
| Prostate Margin Reduction to Reduce Acute Rectal Toxicity (PROTRACT) | NCT04004858 | Prostate Cancer | External beam r... | 18 Years - | Southlake Regional Health Centre | |
| 5500/20 vs. SABR or Brachytherapy for PRimary OligoMetastatic Prostate Cancer Treatment (PROMPT) | NCT04610372 | Oligometastatic... | Hypofractionate... High dose rate ... Permanent seed ... Stereotactic bo... | 18 Years - | British Columbia Cancer Agency | |
| Safety of IMRT Treatment With Inhomogeneous Dose in Patients With Relapsed High-grade Gliomas. | NCT04610229 | Glioblastoma Mu... Glioblastoma Glioblastoma, A... | Hypofractionati... | 18 Years - | Arcispedale Santa Maria Nuova-IRCCS | |
| Accelerated Hypofractionated Radiotherapy in the Treatment of Malignant Pleural Mesothelioma | NCT03269227 | Malignant Pleur... | Accelerated hyp... | 18 Years - 85 Years | Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori | |
| Safety and Efficacy Study of Dose-escalated Hypofractionated Radiotherapy For Prostate Cancer | NCT01146340 | Prostate Cancer | Hypofractionate... | 18 Years - | Sunnybrook Health Sciences Centre | |
| Hypofractionation And Ultra-Hypofractionation In Adjuvant Radiotherapy For Breast Cancer | NCT04434677 | Breast Cancer | Hypofractionati... ultraHypofracti... | 50 Years - | Alexandria University | |
| Pre-operative Hypofractionated Proton Therapy | NCT05917301 | Soft Tissue Sar... | hypofractionati... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Hypofractionated Radiotherapy for Prostate Cancer | NCT02311049 | Prostate Cancer | Hypofractionati... | 40 Years - 80 Years | University Hospital, Ghent | |
| 2-weeks of Adjuvant Radiotherapy in Patients With Breast Cancer | NCT02460744 | Breast Cancer | Hypofractionati... | 18 Years - 85 Years | PIMERIndia | |
| Hypofractionated Radiotherapy as Primary Therapy for Prostate Cancer | NCT01921803 | Prostate Cancer | hypofractionati... | 40 Years - 80 Years | University Hospital, Ghent | |
| Hypofractionated Radiotherapy in Breast Cancer Patients With Prosthetic Reconstruction | NCT05491395 | Breast Cancer | Hypofractionati... | 18 Years - | Barretos Cancer Hospital | |
| Trial of Ultrahypofractionated Focal Salvage Radiotherapy for Isolated Prostate Bed Recurrence After Radical Prostatectomy | NCT05746806 | Recurrent Prost... | Ultrahypofracti... Androgen depriv... | 18 Years - 100 Years | Insel Gruppe AG, University Hospital Bern | |
| HYPofractionated Adjuvant RadioTherapy in 1 Versus 2 Weeks in High-risk Patients With Breast Cancer (HYPART). | NCT04472845 | Breast Cancer Hypofractionati... Radiotherapy Si... | 1 week RT 2 week RT | 18 Years - | PGIMER | |
| Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma | NCT03422003 | Breast Cancer | Radiation Thera... | 18 Years - | Dana-Farber Cancer Institute | |
| Hypofractionated Radiotherapy for Prostate Cancer | NCT02311049 | Prostate Cancer | Hypofractionati... | 40 Years - 80 Years | University Hospital, Ghent | |
| Ion Irradiation of Sacrococcygeal Chordoma | NCT01811394 | Sacral Chordoma | protons carbon ions | 18 Years - 80 Years | Heidelberg University | |
| MR-based Hypofractionated Adaptive IGRT of Prostate Cancer (M-base HyPro 2.0) | NCT03880851 | Prostate Cancer | Plan adaptation... | 18 Years - | University Hospital Tuebingen | |
| Weekly Single Fraction Hypofractionated Adjuvant Radiotherapy for Early Stage Breast Cancer | NCT04580784 | Breast Cancer Radiotherapy Si... | Weekly hypofrac... | 40 Years - | Kasr El Aini Hospital | |
| Ion Prostate Irradiation | NCT01641185 | Prostatic Neopl... | radiation | 40 Years - 80 Years | Heidelberg University | |
| Stereotactic Precision And Conventional Radiotherapy Evaluation | NCT01920789 | Non-small Cell ... | Stereotactic ra... Conventionally ... | - | Swedish Lung Cancer Study Group | |
| Whole Breast + Lymph Node Irradiation: Prone Compared to Supine Position in 15 or 5 Fractions | NCT03280719 | Breast Neoplasm... Radiotherapy Lymph Node Meta... | Prone Radiother... Acceleration Supine Radiothe... Hypofractionati... | 18 Years - | University Hospital, Ghent | |
| Study of Radiation Fractionation on Patient Outcomes After Breast REConstruction (FABREC) for Invasive Breast Carcinoma | NCT03422003 | Breast Cancer | Radiation Thera... | 18 Years - | Dana-Farber Cancer Institute | |
| Prostate Margin Reduction to Reduce Acute Rectal Toxicity (PROTRACT) | NCT04004858 | Prostate Cancer | External beam r... | 18 Years - | Southlake Regional Health Centre | |
| Pre-operative Hypofractionated Proton Therapy | NCT05917301 | Soft Tissue Sar... | hypofractionati... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| HF-SRT vs. HS-WBRT in Treating Patients With Brain Oligometastases | NCT05807165 | Brain Oligometa... | Hypofractionate... Hippocampus-Spa... | 20 Years - 85 Years | Chang Gung Memorial Hospital | |
| Hypofractionated, Dose Escalation Radiotherapy for High Risk Adenocarcinoma of the Prostate | NCT01444820 | Prostate Cancer | hypofractionati... conventional | 18 Years - | Sir Mortimer B. Davis - Jewish General Hospital | |
| HRQOL in Prostate Cancer Patients Treated With Radiotherapy | NCT05645237 | Prostate Cancer | radiotherapy | - | Erasmus Medical Center | |
| HYpofractionated, Dose-redistributed RAdiotherapy With Protons and Photons in HNSCC | NCT05364411 | Head and Neck S... Hypofractionati... Radiotherapy Proton Therapy Immune System S... | HYpofractionate... conventional fr... | 18 Years - | Erasmus Medical Center | |
| Comparison of the Cosmetic Outcome of Hypofractionated Versus Normofractionated IMRT in Treatment of Breast Cancer | NCT01403779 | Tumors Breast Cancer | intensity modul... | 60 Years - | Universitätsmedizin Mannheim | |
| Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base | NCT05861245 | Chordoma Chondrosarcoma | 5-fraction hipo... | 18 Years - | Quironsalud | |
| HYpofractionated Pelvic Radiotherapy for Advanced Cervical Cancers INeligible for ChemoTherapy | NCT05210270 | Locally Advance... | Hypofractionati... | 18 Years - | University of Santo Tomas Hospital, Philippines | |
| Stereotactic Precision And Conventional Radiotherapy Evaluation | NCT01920789 | Non-small Cell ... | Stereotactic ra... Conventionally ... | - | Swedish Lung Cancer Study Group | |
| Safety and Efficacy Study of Dose-escalated Hypofractionated Radiotherapy For Prostate Cancer | NCT01146340 | Prostate Cancer | Hypofractionate... | 18 Years - | Sunnybrook Health Sciences Centre | |
| A Trial of 15 Fraction vs 25 Fraction Pencil Beam Scanning Proton Radiotherapy After Mastectomy in Patients Requiring Regional Nodal Irradiation | NCT02783690 | Breast Cancer | Hypofractionati... | 18 Years - | Mayo Clinic | |
| Stereotactic Pelvic Adjuvant Radiation Therapy in Cancers of the Uterus II | NCT04890912 | Endometrial Can... | Conventional Fr... Hypofractionati... | 18 Years - | Sunnybrook Health Sciences Centre | |
| Clinical Response and Toxicity of Hypo-fractionated Chemoradiotherapy in Cervix Cancer | NCT04831437 | Cervix Uteri Ca... | Hypofractionate... Standard EBRT | 18 Years - 85 Years | Tehran University of Medical Sciences | |
| Hypofractionation And Ultra-Hypofractionation In Adjuvant Radiotherapy For Breast Cancer | NCT04434677 | Breast Cancer | Hypofractionati... ultraHypofracti... | 50 Years - | Alexandria University | |
| Study of Hypofractionated Proton Beam Radiation Therapy for Prostate Cancer | NCT00831623 | Prostate Cancer | Proton Radiatio... Proton | 18 Years - | Loma Linda University | |
| A Trial of 15 Fraction vs 25 Fraction Pencil Beam Scanning Proton Radiotherapy After Mastectomy in Patients Requiring Regional Nodal Irradiation | NCT02783690 | Breast Cancer | Hypofractionati... | 18 Years - | Mayo Clinic | |
| Advanced Proton Therapy Approaches: a Multicenter High-quality Data Registry | NCT05860361 | Cancer | 18 Years - | European Institute of Oncology | ||
| Advanced Proton Therapy Approaches: a Multicenter High-quality Data Registry | NCT05860361 | Cancer | 18 Years - | European Institute of Oncology | ||
| Early Investigation of High Precision Radiotherapy Prior to Commencing Standard Radiotherapy for Prostate Cancer | NCT02004223 | Prostate Cancer | Dose escalation... | 35 Years - 85 Years | Royal North Shore Hospital | |
| HYpofractionated, Dose-redistributed RAdiotherapy With Protons and Photons in HNSCC | NCT05364411 | Head and Neck S... Hypofractionati... Radiotherapy Proton Therapy Immune System S... | HYpofractionate... conventional fr... | 18 Years - | Erasmus Medical Center | |
| Hypofractionated Radiotherapy in Breast Cancer Patients With Prosthetic Reconstruction | NCT05491395 | Breast Cancer | Hypofractionati... | 18 Years - | Barretos Cancer Hospital | |
| Early Investigation of High Precision Radiotherapy Prior to Commencing Standard Radiotherapy for Prostate Cancer | NCT02004223 | Prostate Cancer | Dose escalation... | 35 Years - 85 Years | Royal North Shore Hospital | |
| 2-weeks of Adjuvant Radiotherapy in Patients With Breast Cancer | NCT02460744 | Breast Cancer | Hypofractionati... | 18 Years - 85 Years | PIMERIndia | |
| HYpofractionated Pelvic Radiotherapy for Advanced Cervical Cancers INeligible for ChemoTherapy | NCT05210270 | Locally Advance... | Hypofractionati... | 18 Years - | University of Santo Tomas Hospital, Philippines | |
| Clinical Response and Toxicity of Hypo-fractionated Chemoradiotherapy in Cervix Cancer | NCT04831437 | Cervix Uteri Ca... | Hypofractionate... Standard EBRT | 18 Years - 85 Years | Tehran University of Medical Sciences | |
| Stereotactic Image-Guided Neoadjuvant Ablative Radiation Then Lumpectomy | NCT02212860 | Early Stage Bre... | Stereotactic Bo... | 50 Years - | Lawson Health Research Institute | |
| Hypofractionation With Simultaneous Integrated Boost for Early Breast Cancer | NCT01948726 | Breast Cancer A... | Hypofractionati... | 18 Years - | University Hospital Schleswig-Holstein | |
| Hypofractionated Adaptive Image-Guided Radiation Therapy for Localized Adenocarcinoma of the Prostate | NCT00809991 | Prostate Cancer | hypofractionati... | 18 Years - 100 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Dose-Escalated Proton Radiation Therapy for High-Risk Prostate Cancer | NCT03624660 | Adenocarcinoma ... | HR-A HR-B | 18 Years - 100 Years | University of Florida | |
| Treatment of High-grade Gliomas Using Hypofractionated Radiation Therapy -a Phase I Clinical Trial | NCT03082846 | Glioma Radiotherapy, I... Maximum Tolerat... | hypofractionate... Temozolomide ch... | 18 Years - 70 Years | The Second Hospital of Hebei Medical University | |
| A Study Comparing Hypofractionated Dose Escalated VMAT to Conventional CCRT in Locally Advanced Head and Neck Cancer | NCT03699969 | Locally Advance... | Hypofractionate... | 18 Years - 70 Years | Cairo University | |
| Study of Hypofractionated Proton Beam Radiation Therapy for Prostate Cancer | NCT00831623 | Prostate Cancer | Proton Radiatio... Proton | 18 Years - | Loma Linda University | |
| Hypofractionated Radiosurgery for Localised Prostate Cancer | NCT02635256 | Prostate Cancer | Hypofractionate... | 60 Years - | University Hospital Schleswig-Holstein | |
| Pre-operative RadiothErapy for Soft Tissue SarcOmas | NCT04617327 | Soft Tissue Sar... | Hypofractionati... | 18 Years - | McGill University Health Centre/Research Institute of the McGill University Health Centre | |
| Ultra Hypofractionnated Radiotherapy With HDR Brachytherapy Boost. | NCT05786742 | Prostate Cancer Radiotherapy Si... Hypofractionati... Brachytherapy Radiotherapy Localized Prost... | grade and compa... | 18 Years - 95 Years | CHU de Quebec-Universite Laval | |
| Safety and Efficacy Study of Dose-escalated Hypofractionated Radiotherapy For Prostate Cancer | NCT01146340 | Prostate Cancer | Hypofractionate... | 18 Years - | Sunnybrook Health Sciences Centre | |
| Postoperative Hypofractionated Intensity-modulated Radiotherapy Endometrial Cancer | NCT05876130 | Endometrial Can... | POHIM_EM | 20 Years - 80 Years | Samsung Medical Center | |
| Safety of IMRT Treatment With Inhomogeneous Dose in Patients With Relapsed High-grade Gliomas. | NCT04610229 | Glioblastoma Mu... Glioblastoma Glioblastoma, A... | Hypofractionati... | 18 Years - | Arcispedale Santa Maria Nuova-IRCCS | |
| Hypofractionated Radiosurgery for Localised Prostate Cancer (HYPOSTAT-II) | NCT03795337 | Prostate Cancer | Hypofractionate... | 60 Years - | University Hospital Schleswig-Holstein | |
| Dose Escalation For INtraprostatic LEsions | NCT05851547 | Prostatic Neopl... | Prostate SBRT w... Triptorelin Inj... | 18 Years - | Ottawa Hospital Research Institute | |
| Pre-operative Hypofractionated Proton Therapy | NCT05917301 | Soft Tissue Sar... | hypofractionati... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| Hypo Versus Conventional Fractionation in Reconstructed-Breast Cancer Mastectomy Patients | NCT05253170 | Breast Cancer Radiotherapy; C... | Hypofractionati... Conventional Fr... | 19 Years - 85 Years | Seoul National University Bundang Hospital | |
| Hypo Versus Conventional Fractionation in Reconstructed-Breast Cancer Mastectomy Patients | NCT05253170 | Breast Cancer Radiotherapy; C... | Hypofractionati... Conventional Fr... | 19 Years - 85 Years | Seoul National University Bundang Hospital | |
| Effectiveness of the SpaceOAR Vue System in Subjects With Prostate Cancer Being Treated With Stereotactic Body Radiotherapy | NCT04905069 | Prostate Cancer | SpaceOAR Vue Sy... | 18 Years - | Boston Scientific Corporation | |
| Comparison of the Cosmetic Outcome of Hypofractionated Versus Normofractionated IMRT in Treatment of Breast Cancer | NCT01403779 | Tumors Breast Cancer | intensity modul... | 60 Years - | Universitätsmedizin Mannheim |
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