Spots Global Cancer Trial Database for metformin hydrochloride
Every month we try and update this database with for metformin hydrochloride cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Metformin and Chemotherapy in Treating Patients With Stage III-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer | NCT02122185 | Brenner Tumor Malignant Ascit... Malignant Pleur... Ovarian Clear C... Ovarian Endomet... Ovarian Mixed E... Ovarian Serous ... Ovarian Undiffe... Recurrent Fallo... Recurrent Ovari... Recurrent Ovari... Recurrent Prima... Stage IIIA Fall... Stage IIIA Ovar... Stage IIIA Ovar... Stage IIIA Prim... Stage IIIB Fall... Stage IIIB Ovar... Stage IIIB Ovar... Stage IIIB Prim... Stage IIIC Fall... Stage IIIC Ovar... Stage IIIC Ovar... Stage IIIC Prim... Stage IV Fallop... Stage IV Ovaria... Stage IV Ovaria... Stage IV Primar... | metformin hydro... placebo Chemotherapy | 18 Years - | University of Chicago | |
| Studying Changes in Breast Density in Patients With Early-Stage Breast Cancer Treated With Metformin Hydrochloride or Placebo on CAN-NCIC-MA.32 | NCT01666171 | Breast Cancer | metformin hydro... clinical observ... diagnostic labo... imaging biomark... medical chart r... digital mammogr... | 18 Years - 74 Years | National Cancer Institute (NCI) | |
| Metformin Hydrochloride, Carboplatin, and Paclitaxel in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer | NCT02050009 | Ovarian Papilla... Ovarian Serous ... Recurrent Fallo... Recurrent Ovari... Recurrent Ovari... Recurrent Prima... | metformin hydro... carboplatin paclitaxel laboratory biom... | 18 Years - | Fox Chase Cancer Center | |
| Metformin Hydrochloride in Preventing Esophageal Cancer in Patients With Barrett Esophagus | NCT01447927 | Barrett Esophag... Esophageal Canc... | metformin hydro... placebo | 18 Years - | National Cancer Institute (NCI) | |
| Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI | NCT01312467 | Adenomatous Pol... Colorectal Canc... Obesity | metformin hydro... | 35 Years - 80 Years | National Cancer Institute (NCI) | |
| Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer | NCT01666730 | Acinar Cell Ade... Duct Cell Adeno... Recurrent Pancr... Stage IV Pancre... | metformin hydro... oxaliplatin leucovorin calc... fluorouracil laboratory biom... | 18 Years - | Case Comprehensive Cancer Center | |
| Trial of Metformin for Colorectal Cancer Risk Reduction for History of Colorectal Adenomas and Elevated BMI | NCT01312467 | Adenomatous Pol... Colorectal Canc... Obesity | metformin hydro... | 35 Years - 80 Years | National Cancer Institute (NCI) | |
| Temozolomide, Memantine Hydrochloride, Mefloquine, and Metformin Hydrochloride in Treating Patients With Glioblastoma Multiforme After Radiation Therapy | NCT01430351 | Glioblastoma Gliosarcoma Supratentorial ... | Mefloquine Memantine Hydro... Metformin Hydro... Temozolomide | 18 Years - | M.D. Anderson Cancer Center | |
| Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML | NCT01849276 | Adult Acute Meg... Adult Acute Min... Adult Acute Mon... Adult Acute Mon... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Erythrole... Adult Pure Eryt... Blastic Phase C... Recurrent Adult... Untreated Adult... | metformin hydro... cytarabine laboratory biom... | 18 Years - | Northwestern University | |
| Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer | NCT01666730 | Acinar Cell Ade... Duct Cell Adeno... Recurrent Pancr... Stage IV Pancre... | metformin hydro... oxaliplatin leucovorin calc... fluorouracil laboratory biom... | 18 Years - | Case Comprehensive Cancer Center | |
| Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse | NCT04758000 | Osteosarcoma Ewing Sarcoma | Metformin Hydro... | 14 Years - | Istituto Ortopedico Rizzoli | |
| Metformin Hydrochloride in Mitigating Side Effects of Radioactive Iodine Treatment in Patients With Differentiated Thyroid Cancer | NCT03109847 | Thyroid | Metformin Hydro... Radioactive Iod... Placebo | 18 Years - 90 Years | Thomas Jefferson University | |
| Metformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma | NCT03829020 | Recurrent Plasm... Refractory Plas... | Bortezomib Metformin Hydro... Nelfinavir Mesy... | 18 Years - | Mayo Clinic | |
| Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer | NCT01905046 | Atypical Ductal... BRCA1 Mutation ... BRCA2 Mutation ... Ductal Breast C... Lobular Breast ... | metformin hydro... placebo | 25 Years - 55 Years | Alliance for Clinical Trials in Oncology | |
| Metformin Hydrochloride and Doxycycline in Treating Patients With Localized Breast or Uterine Cancer | NCT02874430 | Breast Carcinom... Endometrial Cle... Endometrial Ser... Uterine Corpus ... Uterine Corpus ... | Metformin Hydro... Doxycycline | 18 Years - | Thomas Jefferson University | |
| Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome | NCT06256289 | Polycystic Ovar... Non-Alcoholic F... | Canagliflozin 1... Metformin Hydro... | 18 Years - 45 Years | The First Affiliated Hospital of Shanxi Medical University | |
| Gemcitabine Hydrochloride, Paclitaxel Albumin-Stabilized Nanoparticle Formulation, Metformin Hydrochloride, and a Standardized Dietary Supplement in Treating Patients With Pancreatic Cancer That Cannot be Removed by Surgery | NCT02336087 | Pancreatic Aden... Unresectable Pa... Stage III Pancr... Stage IV Pancre... | Gemcitabine Hyd... Paclitaxel Albu... Metformin Hydro... Therapeutic Die... Laboratory Biom... Quality-of-Life... | 18 Years - | City of Hope Medical Center | |
| Efficacy of Canagliflozin Versus Metformin in Women With Polycystic Ovary Syndrome | NCT06256289 | Polycystic Ovar... Non-Alcoholic F... | Canagliflozin 1... Metformin Hydro... | 18 Years - 45 Years | The First Affiliated Hospital of Shanxi Medical University | |
| Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer | NCT01666730 | Acinar Cell Ade... Duct Cell Adeno... Recurrent Pancr... Stage IV Pancre... | metformin hydro... oxaliplatin leucovorin calc... fluorouracil laboratory biom... | 18 Years - | Case Comprehensive Cancer Center | |
| Sintilimab Combined With Metformin in First-Line Chemotherapy Refractory Advanced NSCLC Patients | NCT03874000 | Non Small Cell ... | Sintilimab Metformin Hydro... | 18 Years - 75 Years | Tianjin Medical University Cancer Institute and Hospital | |
| Enzalutamide and Metformin Hydrochloride in Treating Patients With Hormone-Resistant Prostate Cancer | NCT02339168 | Prostate Cancer | Enzalutamide Metformin Hydro... | 18 Years - | University of California, Davis | |
| Probiotic Intervention in PCOS | NCT04593459 | Polycystic Ovar... | Probiotic Metformin Hydro... Probiotic Place... | 18 Years - 45 Years | Medical University of Graz | |
| Probiotic Intervention in PCOS | NCT04593459 | Polycystic Ovar... | Probiotic Metformin Hydro... Probiotic Place... | 18 Years - 45 Years | Medical University of Graz | |
| Metformin Hydrochloride in Affecting Cytokines and Exosomes in Patients With Head and Neck Cancer | NCT03109873 | Larynx Lip Oral Cavity Pharynx | External Beam R... Metformin Hydro... Placebo | 18 Years - 90 Years | Thomas Jefferson University | |
| Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion | NCT02581137 | Erythroplakia Hyperplasia Oral Cavity Car... Oral Leukoplaki... | Laboratory Biom... Metformin Hydro... | 18 Years - | National Cancer Institute (NCI) | |
| Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery | NCT03076281 | Larynx LIP Oral Cavity Pharynx | Metformin Hydro... Doxycycline Metformin +Doxy... | 18 Years - | Thomas Jefferson University | |
| Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery | NCT03048500 | Recurrent Non-S... Stage III Non-S... Stage IIIA Non-... Stage IIIB Non-... Stage IV Non-Sm... | Laboratory Biom... Metformin Hydro... Nivolumab | 18 Years - | Northwestern University | |
| Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery | NCT03076281 | Larynx LIP Oral Cavity Pharynx | Metformin Hydro... Doxycycline Metformin +Doxy... | 18 Years - | Thomas Jefferson University | |
| A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors | NCT05828303 | Advanced Solid ... Metastatic Soli... | TPX-0005 Metformin Hydro... Digoxin Rosuvastatin Ca... | 18 Years - | Turning Point Therapeutics, Inc. | |
| Metformin Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery | NCT01433913 | Adenocarcinoma ... Recurrent Prost... Stage I Prostat... Stage IIA Prost... Stage IIB Prost... | metformin hydro... placebo laboratory biom... | 18 Years - | National Cancer Institute (NCI) | |
| Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer | NCT01905046 | Atypical Ductal... BRCA1 Mutation ... BRCA2 Mutation ... Ductal Breast C... Lobular Breast ... | metformin hydro... placebo | 25 Years - 55 Years | Alliance for Clinical Trials in Oncology | |
| Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia | NCT02948283 | Anemia Fatigue Fever Lymphadenopathy Lymphocytosis Night Sweats Recurrent Chron... Recurrent Plasm... Refractory Chro... Refractory Plas... Splenomegaly Thrombocytopeni... Weight Loss | Laboratory Biom... Metformin Hydro... Pharmacological... Ritonavir Quality-of-Life Questionnaire | 18 Years - | City of Hope Medical Center | |
| Metformin, Nelfinavir, and Bortezomib in Treating Patients With Relapsed and/or Refractory Multiple Myeloma | NCT03829020 | Recurrent Plasm... Refractory Plas... | Bortezomib Metformin Hydro... Nelfinavir Mesy... | 18 Years - | Mayo Clinic | |
| Metformin Hydrochloride in Preventing Breast Cancer in Patients With Atypical Hyperplasia or In Situ Breast Cancer | NCT01905046 | Atypical Ductal... BRCA1 Mutation ... BRCA2 Mutation ... Ductal Breast C... Lobular Breast ... | metformin hydro... placebo | 25 Years - 55 Years | Alliance for Clinical Trials in Oncology | |
| Metformin Hydrochloride in Treating Patients With Pancreatic Cancer That Can be Removed by Surgery | NCT01954732 | Stage IA Pancre... Stage IB Pancre... Stage IIA Pancr... Stage IIB Pancr... | metformin hydro... pharmacological... | 18 Years - | Case Comprehensive Cancer Center | |
| Metformin Plus/Minus Fasting Mimicking Diet to Target the Metabolic Vulnerabilities of LKB1-inactive Lung Adenocarcinoma | NCT03709147 | Advanced LKB1-i... | Metformin Hydro... Cisplatin Carboplatin Pemetrexed Fasting-mimicki... Pembrolizumab | 18 Years - 75 Years | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | |
| Metformin With Standard Taxotere and Prednisone in the Treatment of Castration Resistant Prostate Cancer | NCT01478308 | Prostate Cancer | Metformin hydro... Docetaxel Prednisone | 18 Years - | New Mexico Cancer Care Alliance | |
| A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors | NCT05828303 | Advanced Solid ... Metastatic Soli... | TPX-0005 Metformin Hydro... Digoxin Rosuvastatin Ca... | 18 Years - | Turning Point Therapeutics, Inc. | |
| A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer | NCT01101438 | Breast Cancer | metformin hydro... placebo | 18 Years - 74 Years | Canadian Cancer Trials Group | |
| Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS | NCT05680805 | Polycystic Ovar... Metformin | Metformin Hydro... | 18 Years - 35 Years | Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh |
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