Spots Global Cancer Trial Database for mrna
Every month we try and update this database with for mrna cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| A Phase 1/2 Study to Evaluate OTX-2002 in Patients With Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association With the MYC Oncogene | NCT05497453 | Hepatocellular ... Solid Tumor Hepatocellular ... Hepatocellular ... Hepatocellular ... Liver Cancer Liver, Cancer o... | OTX-2002 Tyrosine kinase... Tyrosine kinase... Checkpoint Inhi... | 18 Years - | Omega Therapeutics | |
| Identify microRNAs in Cachexia in Pancreatic Carcinoma | NCT05275075 | Resectable Panc... | Pancreatic canc... | 18 Years - | University of Oklahoma | |
| Study of IT STX-001 in Patients With Advanced Solid Tumors as Monotherapy or in Combination With Pembrolizumab | NCT06249048 | Advanced Solid ... | STX-001 Keytruda® | 18 Years - | Strand Therapeutics Inc. | |
| Vaccination With Tumor mRNA in Metastatic Melanoma - Fixed Combination Versus Individual Selection of Targeted Antigens | NCT00204516 | Malignant Melan... | mRNA coding for... GM-CSF | 18 Years - 80 Years | University Hospital Tuebingen | |
| Vaccination With Tumor mRNA in Metastatic Melanoma - Fixed Combination Versus Individual Selection of Targeted Antigens | NCT00204516 | Malignant Melan... | mRNA coding for... GM-CSF | 18 Years - 80 Years | University Hospital Tuebingen | |
| Peptide-specific Vaccination in HLA-A*02 Positive Patients With Biochemical Recurrence After Radical Prostatectomy | NCT02452307 | Recurrent Prost... | Peptide vaccine Montanide ISA-5... Granulocyte mac... Imiquimod mRNA Protamin local hyperther... | 45 Years - 80 Years | University Hospital Tuebingen | |
| Feasibility Study of Acute Myelogenous Leukemia mRNA Plus Lysate Loaded Dendritic Cell Vaccines | NCT00514189 | Leukemia | Autologous Dend... | - | M.D. Anderson Cancer Center | |
| A Prospective Study Into the Risk of Colorectal Neoplasms in Individuals With a Family History of Advanced Adenomas (Sibling AN Study) | NCT01593098 | Adenoma CRC | 40 Years - 70 Years | Chinese University of Hong Kong | ||
| Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141 in Patients With Unresectable or Metastatic CLDN18.2-positive Gastric, Pancreatic, Ovarian and Biliary Tract Tumors | NCT04683939 | Solid Tumor Gastric Cancer Gastroesophagea... Esophageal Aden... Pancreatic Canc... Biliary Tract C... Cholangiocarcin... Metastatic Canc... | BNT141 Nab-paclitaxel Gemcitabine | 18 Years - | BioNTech SE | |
| Detection of High Expression Levels of EMT-Transcription Factor mRNAs in Patients With Pancreatic Cancer and Their Diagnostic Potential | NCT04323917 | Pancreatic Canc... | Liquid biopsy | 18 Years - | Istituto Clinico Humanitas | |
| The Role of mRNA-based Urine Test (Xpert Bladder Cancer Monitor) in Predicting the Need for Second Look Biopsy After Transurethral Resection of Non Muscle-invasive Bladder Tumor. | NCT04603612 | Bladder Cancer | Primary TURBT | 18 Years - | Mansoura University | |
| Identification of Molecular Biomarkers for Cancer Target Therapy Efficacy | NCT03724097 | Cancer | RNA sequencing Transcriptome a... target drug wit... target drug wit... non-target drug palliative care | 18 Years - 80 Years | OmicsWay Corp. | |
| Salivary Biomarkers for Non-small Cell Lung Cancer Detection | NCT02294578 | Lung Cancer | 18 Years - | PeriRx | ||
| Local Treatment of Metastatic Melanoma With Autologous Lymphocytes and the Bispecific Antibody rM28 | NCT00204594 | Malignant Melan... | rM28 autologous PBMC... | 18 Years - 75 Years | University Hospital Tuebingen | |
| The Role of mRNA-based Urine Test (Xpert Bladder Cancer Monitor) in Predicting the Need for Second Look Biopsy After Transurethral Resection of Non Muscle-invasive Bladder Tumor. | NCT04603612 | Bladder Cancer | Primary TURBT | 18 Years - | Mansoura University | |
| Molecular Pathway Activation Markers Predicting Efficacy of Trastuzumab Therapy for HER2-positive Breast Cancer | NCT03521245 | HER2-positive B... | RNA sequencing Transcriptome a... Trastuzumab Chemotherapy | 18 Years - 80 Years | OmicsWay Corp. | |
| Intradermal Vaccination With Stabilized Tumor mRNA - a Clinical Phase I/II Trial in Melanoma Patients | NCT00204607 | Malignant Melan... | mRNA GM-CSF s.c. | 18 Years - 75 Years | University Hospital Tuebingen | |
| Feasibility Study of Acute Myelogenous Leukemia mRNA Plus Lysate Loaded Dendritic Cell Vaccines | NCT00514189 | Leukemia | Autologous Dend... | - | M.D. Anderson Cancer Center | |
| Detection of High Expression Levels of EMT-Transcription Factor mRNAs in Patients With Pancreatic Cancer and Their Diagnostic Potential | NCT04323917 | Pancreatic Canc... | Liquid biopsy | 18 Years - | Istituto Clinico Humanitas | |
| Identify microRNAs in Cachexia in Pancreatic Carcinoma | NCT05275075 | Resectable Panc... | Pancreatic canc... | 18 Years - | University of Oklahoma | |
| Role of Novel Urinary Genomic and Metablomic Markers in Diagnosis of Bladder Cancer in Patients With Hematuria | NCT04317261 | Hematuria Bladder Cancer | Xpert Bladder C... | 18 Years - | Mansoura University | |
| "High Levels of EMT-TFs for the Diagnosis of Colorectal Cancer (CRC)" | NCT04323813 | Colorectal Canc... | Liquid biopsy | 18 Years - | Istituto Clinico Humanitas |
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